• Secretion signals have been mapped in several Yop proteins to sequences encoding the amino-terminal 15 amino acid residues ( 11 ). (pnas.org)
  • The calculated molar ratios of the amino acids and the percentages of the N- or C-terminal amino acid residues of the supposed dimers are compatible with those actually found in the sacculus polymer. (nih.gov)
  • Elucidation of the amino acid sequence of fructose-1,6-bis-phosphate aldolase from rabbit muscle has made it possible to assign the positions of the functional groups known to play specific roles in the catalytic activity, and also to locate the buried, exposed, and active site cysteine residues. (uniprot.org)
  • sequence of 164 amino acid residues in the NH2-terminal BrCN peptide. (uniprot.org)
  • In addition, free energy analysis shows polymorphic residues tend to be populated by energetically unfavorable amino acids. (nih.gov)
  • The polymorphic residues and types of amino acids that populate these sites appear to be conserved between two geographically disparate African parasite populations. (nih.gov)
  • The isolation, compositions, and sequences of cyanogen bromide peptides, ranging in size from 3 to 44 residues, have previously been reported (ELZINGA, M. (1971) Biochemistry 10, 224-229, and other papers in the present series). (eurekamag.com)
  • Finally, the position of CB-14 in the actin sequence as residues 120 to 123 was established by isolation of a chymotryptic overlap peptide. (eurekamag.com)
  • The complete sequence of the 374 residues of actin is presented. (eurekamag.com)
  • The NH2-terminal 98 amino acid residues of the murine histocompatibility antigen H-2Db were assigned using radiochemical methodology. (eurekamag.com)
  • The amino acid sequence was obtained from the sequences of 3 CNBr peptides, CN-E, CN-D and CN-B, which comprise residues 1-5, 6-52 and 53-98, respectively. (eurekamag.com)
  • The sequence analysis indicates a length of 48 amino acid residues. (uni-wuerzburg.de)
  • Respond with an integer expressing the number of bases or amino acid residues. (bitlaw.com)
  • Protein tertiary structure can be partly characterized via each amino acid's contact number measuring how residues are spatially arranged. (biomedcentral.com)
  • Here, we seek to use protein contact number to assist with the tertiary fold prediction of novel proteins for which an accurate functional relationship between a protein's primary sequence and its residues' contact numbers must be determined. (biomedcentral.com)
  • Peptide sequence, or amino acid sequence, is the order in which amino acid residues, connected by peptide bonds, lie in the chain in peptides and proteins. (soscholar.com)
  • Since each protein molecule consists of a long chain of amino acid residues, linked to each other by peptide bonds, the hydrolytic cleavage of all peptide bonds is a prerequisite for the quantitative determination of the amino acid residues. (britannica.com)
  • To obtain information about the sequence of the amino acid residues in the protein, the protein is degraded stepwise, one amino acid being split off in each step. (britannica.com)
  • We generated a synthetic peptide (SP-26), corresponding to the amino acid residues 53-78 of bovine P 2 protein, which induced severe clinical and pathological characteristics of experimental autoimmune neuritis (EAN) in Lewis rats. (elsevier.com)
  • The sequence of the last 24 residues of the B-chain is consistent with that previously published (Aird, S.D., Kaiser, I.I., Lewis, R.V. and Kruggel, W.G. (1985) Biochemistry 24, 7054-7058), except at position 20, where Edman degradation gave glycine and mass spectrometry gave glutamic acid. (scripps.edu)
  • ab259418 is a heterodimeric glycoprotein consisting of disulfide-linked p40 and p35 subunits (503 total amino acid residues). (abcam.com)
  • The traditional approach to selective labeling yields only the chemical shifts of the particular amino acid being selected and does not help in establishing a link between adjacent residues along the polypeptide chain, which is important for sequential assignments. (iisc.ernet.in)
  • This leads to the assignment of a tri-peptide segment from the knowledge of the amino acid types of residues: i - 1, i and i + 1, thereby speeding up the sequential assignment process. (iisc.ernet.in)
  • The complete amino acid sequence of prolactin (PRL) from an amphibian species, the bullfrog (Rana catesbeiana), has been determined and conserved residues and domains were analyzed by sequence comparison of PRLs from 15 species of five major vertebrate classes. (elsevier.com)
  • The bullfrog PRL consists of 197 amino acid residues with three disulfide linkages formed between residues 4-11, 58-172, and 189-197. (elsevier.com)
  • Proteins ( / ˈ p r oʊ ˌ t iː n z / or / ˈ p r oʊ t i . ɪ n z / ) are large biomolecules , or macromolecules , consisting of one or more long chains of amino acid residues . (wikipedia.org)
  • A linear chain of amino acid residues is called a polypeptide . (wikipedia.org)
  • The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. (wikipedia.org)
  • The sequence of amino acid residues in a protein is defined by the sequence of a gene , which is encoded in the genetic code . (wikipedia.org)
  • This includes the complete sequence of the amino-terminal cryptic fragment of 290 residues comprising the von Willebrand factor-binding domain. (elsevier.com)
  • The determined sequence of the α chain of glycoprotein Ib contains a region (residues 29-193) with seven repeats, which is indication of gene duplication and is highly homologous to human leucine-rich α 2 -glycoprotein. (elsevier.com)
  • Cardiac calsequestrin contains 391 amino acid residues plus a 19-residue amino-terminal signal sequence. (elsevier.com)
  • The photoaffinity probe 3-(trifluoromethyl)-3-(m-[ 125 I]iodophenyl)diazirine was used to localize the Ca 2+ -regulated hydrophobic site to amino acid residues 192-223. (elsevier.com)
  • First, it has a 31-amino acid extension at its carboxyl terminus (residues 361-391), which contains 71% acidic residues and a second glycosylation site. (elsevier.com)
  • In previous studies, the primary structure of the alpha-chain (Mr = 5,710) was shown to be homologous to the alpha-chain of the lectin from Pisum sativum, the Vicia cracca glucose-specific lectin, and a region in the middle of the concanavalin A sequence (residues 70-121). (scripps.edu)
  • The complete amino acid sequence of the beta-chain (Mr = 17,572) has been determined from 11 tryptic peptides, 4 peptides derived by chemical cleavage of the beta-chain at its three tryptophan residues, 11 peptides obtained after digestion with Staphylococcus aureus protease, and 5 tryptic peptides from the succinylated polypeptide chain. (scripps.edu)
  • The deduced amino acid sequence shows 498 residues which includes conserved motif for sucrose isomerisation {sup 325}RLDRD{sup 329} and 97% identical to palI gene from Klebsiella sp. (osti.gov)
  • There are two main methods used to find the amino acid sequences of proteins. (news-medical.net)
  • The hydrolysis is typically carried out by heating a sample of the protein to over 100 ° C in hydrochloric acid for an extended period of time (at least 24 hours), allowing more time for proteins with bulky hydrophobic groups. (news-medical.net)
  • Amino acids are those L-amino acids commonly found in naturally occurring proteins and are listed in WIPO Standard ST.25 (1998), Appendix 2, Table 3. (uspto.gov)
  • Previously, no consensus signal sequence for translocation has been identified among TTSS effector proteins. (pnas.org)
  • In this work, seven proteins, termed Salmonella -translocated effectors (STE), are described that contain conserved amino acid sequences that direct translocation by TTSS in Salmonella typhimurium . (pnas.org)
  • Unlike proteins exported by the general secretory pathway, TTSS effector proteins are not proteolytically cleaved and have not previously been identified by conserved amino acid sequence motifs within their secretion/translocation signals ( 1 ). (pnas.org)
  • Data largely accumulated from the study of the TTSS-translocated Yop proteins of Yersinia indicate that the TTSS machinery recognizes effector proteins by two signals in their amino termini: a secretion signal and a translocation signal ( 11 ). (pnas.org)
  • Proteins can only leave the ER after this sequence has been cleaved off. (wikipedia.org)
  • The transportation mechanism of proteins containing the KDEL signal sequence is facilitated by KDEL receptors attached to COPII and COPI vesicles. (wikipedia.org)
  • Nonidentities among amino acid sequences of glycoprotein precursors and amino acid sequences of nucleocapsid proteins of Ocozocoautla de Espinosa virus strain AV B1030026, Mexico, and 8 arenaviruses from South America * % Amino acid sequence nonidentity Virus OCEV AMAV CHPV CPXV GTOV JUNV MACV SABV TCRV OCEV -- 43. (thefreedictionary.com)
  • If such preservation is far more frequent than paleontologists have expected, discerning the amino acid sequences in ancient proteins "has enormous potential" for revealing evolutionary relationships among ancient creatures, he adds. (thefreedictionary.com)
  • The simple fact that proteins are built from 20 amino acids while DNA only contains four different bases, means that the 'signal-to-noise ratio' in protein sequence alignments is much better than in alignments of DNA. (nih.gov)
  • Taken together with the generally higher rate of synonymous mutations over non-synonymous ones, this means that the phylogenetic signal disappears much more rapidly from DNA sequences than from the encoded proteins. (nih.gov)
  • In order to apply a powerful pattern recognition algorithm to predict functional sites in proteins, amino acids cannot be used directly as inputs since they are non-numerical variables. (igi-global.com)
  • In another aspect the present invention provides for isolated, recombinant DXPS proteins, such as the proteins having the sequences set forth in SEQ ID NO:4, SEQ ID NO:6 and SEQ ID NO:8. (osti.gov)
  • This phenomenon appears contradictory in that the information in the two overlaid amino acid sequences is strongly interdependent, yet each of the two proteins has evolved to its own well-defined function. (springer.com)
  • Such a degeneracy is familiar from homologous proteins where a given biological function is implemented by many different amino acid sequences. (springer.com)
  • Pillars Article: Evidence for Amino Acid Sequence Differences among Proteins Resembling the L-chain Subunits of Immunoglobulins. (jimmunol.org)
  • Interestingly, this 15-amino acid transactivation sequence is well conserved in NFAT family proteins, although the sequences contiguous to the carboxyl-terminal regions of the NFAT family are much less conserved. (jimmunol.org)
  • The search for genes encoding cytoplasmic components of NFAT, collectively termed NFAT family proteins, led to the isolation of four distinct cDNAs that shared sequence similarities. (jimmunol.org)
  • The existence of this characteristic Rel similarity domain allowed us to divide NFAT family proteins into three distinct regions: an amino-terminal region, a carboxyl-terminal region, and a middle region containing the Rel similarity domain. (jimmunol.org)
  • The amino-terminal region shows significant, albeit weak, sequence similarity among NFAT family proteins and is characterized by the presence of three perfect repeats for NFAT1(NFATp), NFATc, and NFATx and one for NFAT3, containing the sequence SPXXSPXXSPXXXXX(D,E)(D,E), referred to as SP boxes ( 10 ). (jimmunol.org)
  • Amino acid sequences are further limited to those listed in 37 CFR 1.822(b) , which incorporates by reference WIPO Standard ST.25 (1998), Appendix 2, Table 3 (see MPEP § 2422 ), and those L-amino acids that are commonly found in naturally occurring proteins. (bitlaw.com)
  • NA, a type II transmembrane glycoprotein, possesses an enzyme activity that removes sialic acid from host cell glycocongugates as well as newly synthesized viral proteins. (asm.org)
  • Proteins are made up of a sequence of 20 amino acids. (gleekguide.com)
  • Proteins are computationally designed from the level of amino acids to the level of a functional protein complex. (gleekguide.com)
  • How is the elaborate three-dimensional structure of proteins attained, and how is the three-dimensional structure related to the one-dimensional amino acid sequence information? (gleekguide.com)
  • Methods are provided for using the fused gene to produce labeled, chemically modified proteins in vivo and to isolate a protein knowing only the nucleotide sequence of the gene encoding the protein. (patents.com)
  • Sequences of amino acids come into the picture, when you study the structure of peptide chains and proteins. (biologywise.com)
  • Just as 26 letters of the alphabet combine together to form various words, the more than hundred known amino acids combine to form proteins. (biologywise.com)
  • Among them, there are 20 essential amino acids that form all the proteins in the human body. (biologywise.com)
  • Branched chain amino acids form all the proteins of the human body. (biologywise.com)
  • Proteins and peptide chains are created through the formation of peptide bonds between different amino acids. (biologywise.com)
  • With the exception of a few small proteins (peptides) that occur in bacteria , the amino acids that occur in proteins are l- amino acids. (britannica.com)
  • The abundance of hydroxyproline is noteworthy because this amino acid isn't found in other proteins. (cheapbroncosjersey.com)
  • 18 amino acidsVital Proteins collagen contains 18 amino acids, including 8 out of 9 essential amino acids. (cheapbroncosjersey.com)
  • Collagen is a fibrous protein that is particularly high in 3 amino acids (glycine, proline, and hydroxyproline) that help make up the connective tissues in your body, and can be found in animal proteins like eggs, chicken, bone broth, and dairy. (cheapbroncosjersey.com)
  • Proteins are built from a set of only twenty amino acids, each of which has a unique side chain. (cheapbroncosjersey.com)
  • Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. (antibody-antibodies.com)
  • Sequence specific resonance assignment constitutes an important step towards high-resolution structure determination of proteins by NMR and is aided by selective identification and assignment of amino acid types. (iisc.ernet.in)
  • Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes , and which usually results in protein folding into a specific three-dimensional structure that determines its activity. (wikipedia.org)
  • Like other biological macromolecules such as polysaccharides and nucleic acids , proteins are essential parts of organisms and participate in virtually every process within cells . (wikipedia.org)
  • In animals, proteins are needed in the diet to provide the essential amino acids that cannot be synthesized . (wikipedia.org)
  • Most proteins consist of linear polymers built from series of up to 20 different L -α- amino acids . (wikipedia.org)
  • Edman degradation allows the sequence of amino acids in the protein to be discovered with Edman sequencers, which are currently able to sequence peptides up to about 50 amino acids in length. (news-medical.net)
  • The manual sequencing of the tryptic peptic from the alpha and beta chains of dog hemoglobin is described, including evidence for the existence of two alphaT-13 peptides and thus 2 alpha chains, one with threonine and one with alanine at position 130. (nih.gov)
  • The amino acid sequence of the peptide subunits of the peptide moiety of the sacculus polymer (pseudomurein) of Methanobacterium thermoautotrophicum was elucidated by analysing overlapping peptides obtained from partial acid hydrolsates of isolated sacculi. (nih.gov)
  • The isolation of one of the CNBr peptides (CB-14) was complicated by the presence of a Met-Thr bond that was only partially split under standard conditions for cyanogen bromide cleavage in formic acid. (eurekamag.com)
  • CB-14 is a tetrapeptide, Thr-Gln-Ile-Hse, and this sequence completes the characterization of the actin cyanogen bromide peptides. (eurekamag.com)
  • The amino acid sequence of CN-E was determined directly while the sequences of CN-D and CN-B were determined by NH2-terminal sequence analyses and sequence determinations of peptides produced by thrombin, staphylococcal V8 protease, and trypsin cleavage. (eurekamag.com)
  • Alignment of the CNBr peptides was accomplished by NH2-terminal sequence analysis of the H-2Db papain fragment (CN-E to CN-D) and by analyzing peptides from a tryptic digest of the intact H-2Db molecule. (eurekamag.com)
  • Besides allowing input in the format of peptides and MSA, Seq2Logo accepts input as Blast sequence profiles, providing easy access for non-expert end-users to characterize and identify functionally conserved/variable amino acids in any given protein of interest. (dtu.dk)
  • All but two of these sera bound peptides located between positions 236 and 327 in the 907 amino acids of the gp340 polypeptide chain. (microbiologyresearch.org)
  • After purification by chromatographic procedures, these fragments have been used as a source for tryptic and chymotryptic peptides, Thirty-three major tryptic and twenty-two major chymotryptic peptides were purified in nanomole amounts and their amino acid compositions determined. (umn.edu)
  • These peptides were aligned by using the amino-terminal sequence of the intact protein and the sequences of selected arginyl and lysyl cleavage products. (elsevier.com)
  • Gentaur antibody-antibodies.com The Marketplace for Antibodies : Amino acid sequence of cyanogen bromide peptides from the amino-terminal region of chick skicollagen. (antibody-antibodies.com)
  • APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. (antibody-antibodies.com)
  • Peptides: JNK1_3 (c-Jun amino-terminal kinase 1_3) Protein Length:12-25 amino acids. (antibody-antibodies.com)
  • Peptides: EAAT3(Excitatory amino acid transporters 3) Protein Length:12-25 amino acids. (antibody-antibodies.com)
  • The influence of peptide sequence and Leu chirality in linear and cyclic peptides containing 3-[2-(9-anthryl)benzoxazol-5-yl]alanine on interaction with β-cyclodextrin were studied using fluorescence and NMR spectroscopy. (edu.pl)
  • Secondary and tertiary protein structure is highly dependent upon amino-acid sequence in the POLYPEPTIDE CHAIN , which affects the bonding together of the molecule. (thefreedictionary.com)
  • The corresponding amino acid which is brought by the tRNA reacts chemically in the ribosome to form the peptide bond in the forming polypeptide chain of protein. (biology-online.org)
  • The primary structure of this protein is in full agreement with the predicted amino acid sequence of the putative polypeptide encoded by the mitochondrial aap1 gene recently discovered in Saccharomyces cerevisiae. (uni-wuerzburg.de)
  • Moreover, this protein shows 5011/o homology with the amino acid sequence of a putative polypeptide encoded by an unidentified reading frame also discovered near the mitochondrial ATPase subunit 6 genein Aspergillus nidulans. (uni-wuerzburg.de)
  • 1. An isolated nucleic acid comprising a nucleotide sequence encoding a S. epidermis polypeptide selected from the group consisting of SEQ ID NO: 2992, SEQ ID NO: 3209, SEQ ID NO: 4536, SEQ ID NO: 4728, SEQ ID NO: 4737, SEQ ID NO: 5089, SEQ ID NO: 5172, SEQ ID NO: 5318, and SEQ ID NO: 5510. (patents.com)
  • 5. An isolated nucleic acid comprising a nucleotide sequence encoding a S. epidermis polypeptide or fragment thereof, said nucleic acid selected from the group consisting of SEQ ID NO: 155, SEQ ID NO: 372, SEQ ID NO: 1699, SEQ ID NO: 1891, SEQ ID NO: 1900, SEQ ID NO: 2252, SEQ ID NO: 2335, SEQ ID NO: 2481, and SEQ ID NO: 2673. (patents.com)
  • These amino acids link together to form a polypeptide chain, and then folds into a three dimensional structure. (gleekguide.com)
  • The nucleic acid sequence of the gene and the amino acid sequence of the polypeptide have been determined. (patents.com)
  • Submit Comment for If all 18 nucleotides in a particular sequence are translated, how many amino acids would be in the polypeptide? (biology-questions-and-answers.com)
  • Sera from recipients of fragments from the amino-terminal half of the polypeptide chain bound gp340 in Western blot assays and ELISA but were not virus-neutralizing. (microbiologyresearch.org)
  • Human Aldolase-A protein ALDOA Human Recombinant fused to 20 amino acid His Tag at N-terminal produced in E.coli is a single, non-glycosylated, polypeptide chain containing 384 amino acids (1-364 a.a. (antibody-antibodies.com)
  • AFAP1 Human Recombinant produced in E. coli is a single polypeptide chain containing 360 amino acids (250-588) and having a molecular mass of 39.2 kDa. (prospecbio.com)
  • TNNT2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 305 amino acids (1-285 a.a.) and having a molecular mass of 36.4 kDa. (prospecbio.com)
  • PRMT1 Human Recombinant (a.a. 1-353) fused with His-MBP tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 750 amino acids and having a molecular mass of 84 kDa. (prospecbio.com)
  • Analysis of all these fragments provided data that allowed determination of the continuous sequence corresponding to approximately half of the α-chain polypeptide. (elsevier.com)
  • 7) For those nucleotide sequences that are circular in configuration, the enumeration method set forth in paragraph (c)(6) of this section remains applicable with the exception that the designation of the first base of the nucleotide sequence may be made at the option of the applicant. (uspto.gov)
  • In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2 or 4, or the nucleotide sequence set forth in SEQ ID NO:1 or 3, as well as variants thereof. (thefreedictionary.com)
  • The limit of four or more amino acids was established for consistency with limits in place for industry database collections whereas the limit of ten or more nucleotides, while lower than certain industry database limits, was established to encompass those nucleotide sequences to which the smallest probe will bind in a stable manner. (bitlaw.com)
  • Nucleotide sequences are further limited to those that can be represented by the symbols set forth in 37 CFR 1.822(b), which incorporates by reference WIPO Standard ST.25 (1998), Appendix 2, Table 1 (see MPEP § 2422 ). (bitlaw.com)
  • Lane W, Galat A, Harding M, Schreiber S. Complete amino acid sequence of the FK506 and rapamycin binding protein, FKBP, isolated from calf thymus. (labome.org)
  • The complete amino acid sequence of this protein was determined by automated solid phase Edman degradation of the whole protein and of fragments The purification and the amino acid sequence of a proteolipid translated on ribosomes in yeast mitochondria is reported. (uni-wuerzburg.de)
  • The complete amino acid sequence of this protein was determined by automated solid phase Edman degradation of the whole protein and of fragments obtained after cleavage with cyanogen bromide. (uni-wuerzburg.de)
  • Complete Amino Acid Sequence of a Papain-Solubilized Human Histocompatibility Antigen, HLA-B7. (umn.edu)
  • The complete amino acid sequence of aequorin has been determined. (elsevier.com)
  • cDNA cloning was used to deduce the complete amino acid sequence of canine cardiac calsequestrin, the principal Ca 2+ -binding protein of cardiac junctional sarcoplasmic reticulum. (elsevier.com)
  • The subunit structure and complete amino acid sequence of the lectin extracted from Lens culinaris (LcL) seeds was determined. (scripps.edu)
  • As a part of the overall strategy for determining the complete covalent structure of the papain-solubilized portion of the heavy chain of the human histocompatibility antigen H.LA-B7, the protein was dissected into various fragments by a combination of partial acid hydrolysis and cyanogen bromide cleavage. (umn.edu)
  • They provide the basis for the formal alignment of the acid cleavage and cyanogen bromide fragments of the molecule as well as the source material for the elucidation of the primary structure of the HLA-B7 heavy chain. (umn.edu)
  • The purification and the amino acid sequence of a proteolipid translated on ribosomes in yeast mitochondria is reported. (uni-wuerzburg.de)
  • Isolation, purification, and amino acid sequence of lactobin A, one of the two bacteriocins produced by Lactobacillus amylovorus LMG p-13139. (ugent.be)
  • Isolation, purification, and amino ac. (ugent.be)
  • Purification, characterization and sequence analyses of the extracellular giant hemoglobin from Oligobrachia mashikoi. (semanticscholar.org)
  • Determine the composition and terminal amino acids of each chain. (news-medical.net)
  • The unordered composition of an amino acid is often useful information when attempting to determine the ordered sequence of the protein. (news-medical.net)
  • Hi, A request was made a week or two ago for software which will take the amino aci d composition of a peptide fragment and find the location of the peptide in a larger amino acid sequence. (bio.net)
  • Sequence logos are a graphical representation of the information content stored in a multiple sequence alignment (MSA) and provide a compact and highly intuitive representation of the position-specific amino acid composition of binding motifs, active sites, etc. in biological sequences. (dtu.dk)
  • Including additional information about sequence weight and amino acid composition further improves prediction accuracies significantly with the correlation coefficient reaching 0.73. (biomedcentral.com)
  • 3) The bases in the coding parts of a nucleotide sequence shall be listed as triplets (codons). (uspto.gov)
  • The amino acids corresponding to the codons in the coding parts of a nucleotide sequence shall be typed immediately below the corresponding codons. (uspto.gov)
  • 4) A nucleotide sequence shall be listed with a maximum of 16 codons or 60 bases per line, with a space provided between each codon or group of 10 bases. (uspto.gov)
  • Riley M. Nucleotide sequence of the Xdh region in Drosophila pseudoobscura and an analysis of the evolution of synonymous codons. (labome.org)
  • The RNA chain has only the codons, not the amino acids. (biology-online.org)
  • 3/05/2018 · The 3 d the nucleotide sequence of a gene, through medium mrna, is translated into amino acid protein by rules that are known as codons in an mrna molecule do not directly recognize acids they. (gleekguide.com)
  • This mRNA code has a sequence of codons, which provides the order of assembling various amino acids together. (biologywise.com)
  • The enumeration method for amino acid sequences that is set forth in this section remains applicable for amino acid sequences that are circular in configuration, with the exception that the designation of the first amino acid of the sequence may be made at the option of the applicant. (uspto.gov)
  • a) Nucleotide and/or amino acid sequences as used in §§ 1.821 through 1.825 are interpreted to mean an unbranched sequence of four or more amino acids or an unbranched sequence of ten or more nucleotides. (uspto.gov)
  • Sequences with fewer than four specifically defined nucleotides or amino acids are specifically excluded from this section. (uspto.gov)
  • Where a codon spans an intron, the amino acid symbol shall be typed below the portion of the codon containing two nucleotides. (uspto.gov)
  • This definition sets forth limits, in terms of numbers of amino acids and/or numbers of nucleotides, at or above which compliance with the sequence rules is required. (bitlaw.com)
  • The Office does not want to exclude linkages of the type commonly found in naturally occurring nucleotides, e.g., eukaryotic end capped sequences. (bitlaw.com)
  • 9. A probe comprising a nucleotide sequence consisting of at least 40 nucleotides of a nucleotide sequence selected from the group consisting of SEQ ID NO: 155, SEQ ID NO: 372, SEQ ID NO: 1699, SEQ ID NO: 1891, SEQ ID NO: 1900, SEQ ID NO: 2252, SEQ ID NO: 2335, SEQ ID NO: 2481, and SEQ ID NO: 2673. (patents.com)
  • Here we investigate the sequence conservation and evolution of all the metazoan remaining genes for EAA pathways. (mdpi.com)
  • High sequence conservation in the paraphyletic group Plant-Fungi was identified for these two genes using a newly developed Python algorithm. (mdpi.com)
  • Selective pressure analysis of ALS and BHMT protein sequences showed higher non-synonymous mutation ratios in comparisons between metazoans/fungi and metazoans/plants, supporting the hypothesis that these two genes have undergone non-ToL evolution in animals. (mdpi.com)
  • I. General organization of the locus and sequence comparisons of genes s15 and s19 in evolutionary distant species. (labome.org)
  • These data demonstrate that the 15-amino acid sequence of NFATx1 is a major transactivation sequence required for induction of genes by NFATx1 in T cells and possibly regulates NFAT activity through tissue-specific alternative splicing. (jimmunol.org)
  • As a result, one of the most powerful approaches for gaining insight into genome sequences is based simply on amino acid sequence comparisons between new, uncharacterized amino acid sequences predicted from genome DNA sequences, and amino acid sequences of known function. (thefreedictionary.com)
  • Then other molecules in the cell, the transfer molecules (tRNA), bring corresponding amino acids to match each codon (a three letter code on the RNA chain). (biology-online.org)
  • The tRNA molecules have to bring a corresponding amino acid to match each codon on the RNA chain. (biology-online.org)
  • Allelic variation of the DRB1 DNA sequence can result in 3rd HVR amino acid sequences that differ for overall 3rd HVR charge and can impact the steric interaction between HLA molecules and T cells. (biomedcentral.com)
  • They are carbon compounds, made from an amine group (-NH 2 ), carboxylic acid group (-COOH), and a chain of carbon molecules of varying types. (biologywise.com)
  • Protein molecules are made of strings of amino acids in a particular order. (cheapbroncosjersey.com)
  • In other aspects, replicable recombinant cloning vehicles are provided which code for plant 1-deoxyxylulose-5-phosphate synthases, or for a base sequence sufficiently complementary to at least a portion of 1-deoxyxylulose-5-phosphate synthase DNA or RNA to enable hybridization therewith. (osti.gov)
  • In yet other aspects, modified host cells are provided that have been transformed, transfected, infected and/or injected with a recombinant cloning vehicle and/or DNA sequence encoding a plant 1-deoxyxylulose-5-phosphate synthase. (osti.gov)
  • 2. A recombinant expression vector comprising the nucleic acid of claim 1 operably linked to a transcription regulatory element. (patents.com)
  • The short CT contains six highly conserved amino acids ( 7 ) with no known function(s) in virus biology. (asm.org)
  • Firstly, hydrolysis of a known quantity of the protein should break it up into the amino acid monomers. (news-medical.net)
  • Hydrolysis is most frequently accomplished by boiling the protein with concentrated hydrochloric acid . (britannica.com)
  • and (iii) building a multiple DNA alignment by 'reverse translation' of the aligned protein sequences. (nih.gov)
  • B) Structure-based sequence alignment of family 3a CBDs. (asm.org)
  • A structure-based alignment of selected CBD sequences is shown in Fig. 1B . (asm.org)
  • Many software packages for sequence alignment and the construction of evolutionary trees have implemented their own standard of saving and reading sequence alignments. (mybiosoftware.com)
  • This letter system was defined by the IUPAC and IUBMB in 1983, and is as follows: K-Lysine D-Aspartic acid E-Glutamic acid L-Leucine Therefore, the KDEL sequence in three letter code is: Lys-Asp-Glu-Leu. (wikipedia.org)
  • The abbreviation HDEL follows the same notation as KDEL: H-Histidine D-Aspartic acid E-Glutamic acid L-Leucine Three letter code is: His-Asp-Glu-Leu. (wikipedia.org)
  • abstract = "Three Lactococcus lactis strains with the ability to secrete various amino acids (leucine, isoleucine, methionine, valine, glutamic acid, and histidine) were sequenced in order to identify the mechanisms involved in the secretion. (rug.nl)
  • It is helpful to know which amino acid is at the N-terminus of the protein both for ordering of the peptide fragments into the whole chain and to reduce the impact of impurities that commonly occur in the first round of Edman degradation. (news-medical.net)
  • Use the fragments to determine amino acid sequence. (news-medical.net)
  • The amino acid sequences of the Fd fragments of two human pathological immunoglobulins of the immunoglobulin G1 class are reported. (biochemj.org)
  • If a nucleotide sequence contains both DNA and RNA fragments, the type shall be "DNA. (bitlaw.com)
  • wherein the amino acid sequences of the coupled-fragments comprise a T-helper epitope and peptide fragments corresponding to the respective extracellular domains of the receptor. (freepatentsonline.com)
  • the order in which AMINO ACIDS are placed along a protein molecule (see PRIMARY STRUCTURE ). (thefreedictionary.com)
  • The method provides a complex comprising a polymerase enzyme, a target nucleic acid molecule, and a primer, wherein the complex is immobilized on a support Fluorescent label is attached to a terminal phosphate group of the nucleotide or nucleotide analog. (osti.gov)
  • This represents the 1st extensive, continuous sequence information for a histocompatibility antigen encoded by the H-2D locus and allows comparison with the recently determined amino acid sequence of the H-2Kb molecule. (eurekamag.com)
  • 1. An isolated DNA molecule encoding streptavidin and comprising the nucleic acid coding sequence set forth in FIG. 3. (patents.com)
  • Whether presented sequence molecule is DNA, RNA, or PRT (protein). (bitlaw.com)
  • However, the β1 chain of the HLA-DR molecule encoded by HLA-DRB1 is characterized by three regions of amino acid sequence hypervariability and the third hypervariable region (3rd HVR) is thought to be the most important site for T-cell recognition [ 4 ]. (biomedcentral.com)
  • The recipe or the code for creation of any protein is encoded in the DNA (Deoxyribonucleic Acid) molecule. (biologywise.com)
  • Nucleic Acids Research , 40 (W1), W281-W287. (dtu.dk)
  • Such a cleavage is essential for viral infectivity because in the acidic pH of the endosome it exposes a membrane fusion peptide at the amino terminus of the HA2 subunit required for membrane fusion ( 26 ). (asm.org)
  • These signals are insensitive to frameshift mutations ( 12 ), suggesting that the recognized signal lies within the mRNA sequence. (pnas.org)
  • From the strand of mRNA, that is transported in the cytoplasm, tRNA (transfer RNA) carry the information about the sequence, to a ribosome site for protein assembly. (biologywise.com)
  • This study aimed to obtain the complete cDNA coding sequences of aqp1 and aqp3 from the gills of Protopterus annectens , and to determine their branchial mRNA and protein expression levels during the induction, maintenance and arousal phases of aestivation. (frontiersin.org)
  • Second, its mRNA contains a second open reading frame with the capacity to code for a 111-amino acid protein. (elsevier.com)
  • These results show that although the sequences of NA CT and TMD per se are not absolutely essential for the virus life cycle, specific amino acid sequences play a critical role in providing structural stability, enzyme activity, and lipid raft association of NA. (asm.org)
  • An alternative approach is the method of amino acid selective `unlabeling' or reverse labeling, which involves selective unlabeling of specific amino acid types against a uniformly C-13/N-15 labeled background. (iisc.ernet.in)
  • DNA sequence analysis of the p20K cDNA predicted a novel protein distantly related to alpha 2 mu-globulin and plasma retinol-binding protein. (labome.org)
  • This protein sequence agrees completely with that deduced from the cDNA sequence reported by Lopez et al. (elsevier.com)
  • Specifically defined" means those amino acids other than "Xaa" and those nucleotide bases other than "n" defined in accordance with the World Intellectual Property Organization (WIPO) Handbook on Industrial Property Information and Documentation, Standard ST.25: Standard for the Presentation of Nucleotide and Amino Acid Sequence Listings in Patent Applications (1998), including Tables 1 through 6 in Appendix 2, herein incorporated by reference. (uspto.gov)
  • Modifications, e.g. , methylated bases, may be described as set forth in WIPO Standard ST.25 (1998), Appendix 2, Table 2, but shall not be shown explicitly in the nucleotide sequence. (uspto.gov)
  • 1) A nucleotide sequence shall be listed using the lower-case letter for representing the one-letter code for the nucleotide bases set forth in WIPO Standard ST.25 (1998), Appendix 2, Table 1. (uspto.gov)
  • 2) The bases in a nucleotide sequence (including introns) shall be listed in groups of 10 bases except in the coding parts of the sequence. (uspto.gov)
  • Leftover bases, fewer than 10 in number, at the end of noncoding parts of a sequence shall be grouped together and separated from adjacent groups of 10 or 3 bases by a space. (uspto.gov)
  • 6) The enumeration of nucleotide bases shall start at the first base of the sequence with number 1. (uspto.gov)
  • three bases provide the code for each amino acid. (thefreedictionary.com)
  • Using the single-letter code, plug in the amino acids you wish to locate and Sequencher will find and highlight the bases within the sequence that code for those amino acids. (genecodes.com)
  • Sequencher can easily go to the next set of bases that comply with the search by selecting the Find Next button in the Find Amino Acids window. (genecodes.com)
  • In aqueous solutions they are dipolar ions (zwitterions, or hybrid ions) that react with strong acids or bases in a way that leads to the neutralization of the negatively or positively charged ends, respectively. (britannica.com)
  • Because of their reactions with strong acids and strong bases, the amino acids act as buffers-stabilizers of hydrogen ion (H + ) or hydroxide ion (OH − ) concentrations. (britannica.com)
  • As a result, each of the amino acids, except glycine, can exist in two different spatial, or geometric, arrangements (i.e., isomers ), which are mirror images akin to right and left hands. (britannica.com)
  • In fact, glycine is frequently used as a buffer in the pH range from 1 to 3 (acid solutions) and from 9 to 12 (basic solutions). (britannica.com)
  • In acid solutions, glycine has a positive charge and therefore migrates to the cathode (negative electrode of a direct-current electrical circuit with terminals in the solution). (britannica.com)
  • Most of the monoamino acids (i.e., those with only one amino group) have isoelectric points similar to that of glycine. (britannica.com)
  • It is characterized by the predominance of glycine, proline and hydroxyproline, which represent about 50% of the total amino acid content. (cheapbroncosjersey.com)
  • There are three amino acids important for collagen synthesis: proline, lysine, and glycine," says registered dietitian and beauty expert Katey Davidson, MScFN, RD. (cheapbroncosjersey.com)
  • The triple-helical structure of collagen arises from an unusual abundance of three amino acids: glycine, proline, and hydroxyproline. (cheapbroncosjersey.com)
  • abstract = "Seq2Logo is a web-based sequence logo generator. (dtu.dk)
  • The Cycle 1 results indicate that the N-terminal amino acid residue is D (aspartic acid). (shimadzu.com)
  • The existence of heavy chain variable region subgroups is also deduced, from a comparison of these two sequences with those of another γ 1 chain, Eu, a μ chain, Ou, and the partial sequence of a fourth γ 1 chain, Ste. Carbohydrate has been found to be linked to an aspartic acid residue in the variable region of one of the γ 1 chains, Cor. (biochemj.org)
  • Any peptide or protein that can be expressed as a sequence using the symbols in WIPO Standard ST.25 (1998), Appendix 2, Table 3 in conjunction with a description in the Feature section to describe, for example, modified linkages, cross links and end caps, non-peptidyl bonds, etc., is embraced by this definition. (uspto.gov)
  • With regard to amino acid sequences, the use of the terms "peptide or protein" implies, however, that the amino acids in a given sequence are linked by at least three consecutive peptide bonds. (bitlaw.com)
  • Protein primary structure is the linear sequence of amino acids in a peptide or protein. (cheapbroncosjersey.com)
  • The algorithm I used is a bit complicated, but just in case you're curious: since the gene is expressed as a surface protein antibodies can sense, it's considered as a string of amino acids. (stephan-zielinski.com)
  • The HA protein, a type I transmembrane protein, is responsible for binding to the cell surface sialic acid (the receptor), eliciting neutralizing antibodies, and mediating virus entry into the cell by fusion of the viral membrane with the endosomal membrane ( 46 ). (asm.org)
  • Amino acid sequence of rabbit muscle aldolase and the structure of the active center. (uniprot.org)
  • To investigate the role of amino acid sequences of the CT and TMD on the virus life cycle, we systematically mutagenized the entire CT and TMD of NA by converting two to five contiguous amino acids to alanine. (asm.org)
  • In bacteria, d -alanine and some other d -amino acids have been found as components of gramicidin and bacitracin. (britannica.com)
  • By the processes of TRANSCRIPTION and TRANSLATION the DNA -base sequence is mirrored in the amino-acid sequence, there generally being COLINEARITY between DNA and protein in PROKARYOTES . (thefreedictionary.com)
  • The protein primary structure conventionally begins at the amino-terminal (N) end and continues until the carboxyl-terminal (C) end. (news-medical.net)
  • The sequence of a protein is usually notated as a string of letters, according to the order of the amino acids from the amino-terminal to the carboxyl-terminal of the protein. (news-medical.net)
  • Here we provide evidence showing that 15 amino acids in the carboxyl-terminal end of NFATx1 are required for its maximum transactivation activity in Jurkat T cells. (jimmunol.org)
  • Finally, in contrast to the middle and the amino-terminal regions, little is known about the carboxyl-terminal region, which shows no significant sequence similarities. (jimmunol.org)
  • Their sequence is created through the bonding of the carboxyl group of one amino acid, with the amino group of another. (biologywise.com)
  • The sequence is generally reported from the N-terminal end containing free amino group to the C-terminal end containing free carboxyl group. (soscholar.com)
  • By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end. (cheapbroncosjersey.com)
  • All proteinogenic amino acids possess common structural features, including an α-carbon to which an amino group, a carboxyl group, and a variable side chain are bonded . (wikipedia.org)
  • Other than that, rare/non proteinaceous amino acids, modified amino acids (hydroxylysine, hydroxyproline etc.) are present at specific sequence points to add to the framework of the tertiary and quarternary structure of the protein. (gleekguide.com)
  • The structure of a protein may be directly sequenced or inferred from the sequence of DNA. (news-medical.net)
  • KDEL is a target peptide sequence in mammals and plants located on the C-terminal end of the amino acid structure of a protein. (wikipedia.org)
  • HDEL is a target peptide sequence in plants and yeasts located on the C-terminal end of the amino acid structure of a protein. (wikipedia.org)
  • Peptide sequence is often called protein sequence if it represents the primary structure of a protein. (soscholar.com)
  • Scoring protein sequence alignments II PAM1 matrix: answers question, "if 1% of the amino acids in a sequence change, at what rates would each amino acid be substituted for each other one? (gleekguide.com)
  • Scoring protein sequence alignments II Substitution matrices PAM (Accepted Point Mutation, but "PAM" easier to say than "APM") matrix PAM1 matrix: answers question, "if 1% of the amino. (gleekguide.com)
  • Using protein local sequences with multiple sequence alignments (PSI-BLAST profiles), we demonstrate a correlation coefficient between predicted and observed contact numbers of 0.70, which outperforms previously achieved accuracies. (biomedcentral.com)
  • ForCon is a user-friendly software tool for the conversion of nucleic acid and amino acid sequence alignments. (mybiosoftware.com)
  • ForCon : a software tool for the conversion of sequence alignments. (mybiosoftware.com)
  • Those amino acid sequences containing D-amino acids are not intended to be embraced by this definition. (uspto.gov)
  • 37 CFR 1.821(a)(1) and 37 CFR 1.821(a)(2) present further definitions for those nucleotide and amino acid sequences that are intended to be embraced by the sequence rules. (bitlaw.com)
  • The mechanism by which TTSS recognize a diverse array of effectors with no apparent consensus signal sequence remains elusive. (pnas.org)
  • What mechanism is responsible for the sequencing of amino acids? (physicsforums.com)
  • What mechanism is responsible for sequencing of amino acid? (biology-online.org)
  • In addition, we also made two chimeric NA by replacing the CT proximal one-third amino acids of the NA TMD [NA(1T2N)NA] and the entire NA TMD (NATRNA) with that of human transferrin receptor (TR) (a type II transmembrane glycoprotein). (asm.org)
  • We report the amino acid sequence of a 299-residue segment from the α chain of the human platelet membrane glycoprotein Ib. (elsevier.com)
  • 37 CFR 1.821 Nucleotide and/or amino acid sequence disclosures in patent applications. (uspto.gov)
  • b) Patent applications which contain disclosures of nucleotide and/or amino acid sequences, in accordance with the definition in paragraph (a) of this section, shall, with regard to the manner in which the nucleotide and/or amino acid sequences are presented and described, conform exclusively to the requirements of §§ 1.821 through 1.825 . (uspto.gov)
  • 37 CFR 1.821(a) presents a definition for "nucleotide and/or amino acid sequences. (bitlaw.com)
  • The requirement for compliance in 37 CFR 1.821(c) is directed to "disclosures of nucleotide and/or amino acid sequences. (bitlaw.com)
  • All sequence information, whether claimed or not, that meets the length thresholds in 37 CFR 1.821(a) is subject to the rules. (bitlaw.com)
  • 1) If the "Sequence Listing" required by § 1.821(c) is submitted on paper: The "Sequence Listing," setting forth the nucleotide and/or amino acid sequence and associated information in accordance with paragraph (b) of this section, must begin on a new page and must be titled "Sequence Listing. (bitlaw.com)
  • 2) If the "Sequence Listing" required by § 1.821(c) is submitted on compact disc: The "Sequence Listing" must be submitted on a compact disc in compliance with § 1.52(e) . (bitlaw.com)
  • The presentation of the "Sequence Listing" and other materials on compact disc under § 1.821(c) does not substitute for the Computer Readable Form that must be submitted on disk, compact disc, or tape in accordance with § 1.824 . (bitlaw.com)
  • The preceding steps should be repeated with a different fragment pattern so that the overall protein sequence can be reconstructed with minimal errors. (news-medical.net)
  • 1. The assumed specifically active fragment of bovine fibrinopeptide B with the amino acid sequence 15-21 and the fragment 12-21 containing the tripeptide residue Asp 12 -Arg 13 -Pro 14 have been synthesized. (springer.com)
  • 9. The antigenic conjugate as claimed in claim 5, wherein the amino acid sequence of the coupled-fragment is SEQ ID NO. 5, SEQ ID NO. 6, SEQ ID NO. 7 or a combination thereof. (freepatentsonline.com)
  • The 5'-most c-abl promoter contains several sequence motifs that are highly conserved between mouse and man. (labome.org)
  • Sequences from Malawi (GenBank Accession numbers: JN634586- JN634642) were accessed from a previously published study from our group. (nih.gov)
  • The Gambian pfcsp sequences (GenBank Accession numbers: JX885511-JX885521) derive from 55 participants in a clinical trial in the year 2000 [20], [21], and were generated by di-deoxy fluorescent capillary sequencing at The London School of Hygiene & Tropical Medicine (LSHTM). (nih.gov)
  • Amino acids with side chains that are neither aromatic not aliphatic control the piano and organ: the nine non-hydrophobics the piano, and the four hydrophobics the organ. (stephan-zielinski.com)
  • The three amino acids with aliphatic side chains control the low synthesizer, while the four with aromatics control the percussion. (stephan-zielinski.com)
  • Charged amino acid side chains can form ionic bonds, and polar amino acids are capable of forming hydrogen bonds. (cheapbroncosjersey.com)
  • A substitution of cytosine for guanine, also located in VD 1, resulted in Gln instead of Glu at amino acid position 117, as found in genotype B and strain 6BC (numbering according to the ompA amino acid sequence of the C. (thefreedictionary.com)
  • There are two main steps to determine the frequency of amino acids in a process known as amino acid analysis. (news-medical.net)
  • Their analysis of the protein also showed that the amino acid sequence in this region shares some important characteristics with the active agent of bee venom, which works by forming holes in membranes. (thefreedictionary.com)
  • The probability that an amino acid in an ancestral sequence is correctly reconstructed by the likelihood analysis ranged from 91.3 to 98.7% for the four ancestral sequences. (genetics.org)
  • Using the information from these parasite populations, structural analysis reveals that polymorphic amino acids within TH2 and TH3 colocalize to one side of the protein, surround, but do not involve, the hydrophobic pocket in CS, and predominately involve charge switches. (nih.gov)
  • This analysis employs the Edman method (sequential cleaving of amino acids from the N-terminal of the protein to determine the amino acid sequence), which is the most reliable method for determining amino acid sequences. (shimadzu.com)
  • The PPSQ-31A/33A Protein Sequencer System automates the Edman reaction, HPLC separation and detection, and data analysis to determine the amino acid sequence from the N-terminal. (shimadzu.com)
  • Analysis to the 21st residue reveals the sequence from the N-terminal to be: Asp-Val-Val-Met-Thr-Gln-Thr-Pro-Leu-Thr-Leu-Ser-Val-Thr-Ile-Gly-Gln-Pro-Ala-Ser-Ile. (shimadzu.com)
  • In turn, each residue's contact number can be partially predicted from primary amino acid sequence, assisting tertiary fold analysis from sequence data. (biomedcentral.com)
  • Analysis was conducted according to DRβ1 3rd HVR sequence, charge, and parental inheritance. (biomedcentral.com)
  • When subjected to sequence analysis using tandem mass spectrometry, pyroglutamate was found at the amino-terminal end, even though earlier attempts to de-block with pyroglutamate aminopeptidase were unsuccessful. (scripps.edu)
  • Although this bacterium is unable to degrade cellulose, the sequence analysis of its genome revealed the presence of a large cellulosomal gene cluster ( 12 ). (asm.org)