• Arginine has only comparatively recently emerged as an intriguing amino acid in animal metabolism. (karelsavry.us)
  • In the urea cycle (Fig. 4.2), the metabolism of arginine, ornithine, citrulline and argini-nosuccinate is linked in a pathway that enables mammals to dispose of excess N from amino acids that cannot be used for anabolic purposes. (karelsavry.us)
  • Abscisic Acid is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism. (adooq.cn)
  • Remnants of the urea cycle may also be found in birds and reptiles, despite their reliance on uric acid as the major route of disposal of waste N. Thus arginase is found in the liver and kidney of birds, with higher activity in the latter organ. (karelsavry.us)
  • Lesinurad is a selective uric acid re-absorption inhibitor (SURI) and is also a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. (adooq.cn)
  • N-formylmethionine (which is often the initial amino acid of proteins in bacteria, mitochondria, and chloroplasts) is generally considered as a form of methionine rather than as a separate proteinogenic amino acid. (wikipedia.org)
  • These are all L-stereoisomers ("left-handed" isomers), although a few D-amino acids ("right-handed") occur in bacterial envelopes, as a neuromodulator (D-serine), and in some antibiotics. (wikipedia.org)
  • Considering its biochemical properties of inactivating various enzymes that require either bivalent metallic ions or PLP as cofactors, mimosine may have a role in plant defense, and based on its chemical composition, it may serve as a reservoir of carbon and nitrogen for survival and growth under nutrient-limiting conditions. (plantphysiol.org)
  • Inhibition of cyclin D1 expression or induction of cyclin-dependent kinase inhibitor p21WAF1 expression was found in mimosine-treated lung cancer cells. (spandidos-publications.com)
  • GSK2330672 is a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor. (adooq.cn)
  • These are structural analogues of certain nutritionally important amino acids. (karelsavry.us)
  • Many important proteinogenic and non-proteinogenic amino acids have biological functions. (wikipedia.org)
  • Because of their biological significance, amino acids are important in nutrition and are commonly used in nutritional supplements, fertilizers, and food technology. (wikipedia.org)
  • In the form of proteins, amino acid residues form the second-largest component (water is the largest) of human muscles and other tissues. (wikipedia.org)
  • The last of the 20 common amino acids to be discovered was threonine in 1935 by William Cumming Rose, who also determined the essential amino acids and established the minimum daily requirements of all amino acids for optimal growth. (wikipedia.org)
  • 175-6 °C.[citation needed] Mimosine arrests dividing cells in the late G1 phase by inhibiting DNA replication initiation. (wikipedia.org)
  • Vitamin analysis yielded ascorbic acid 13.5 mg/100g, thiamine 0.60, riboflavin 1.10, and niacin 0.40. (stuartxchange.com)
  • Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. (wikipedia.org)
  • Synthesis de novo , acquisition by salvage and interconversion of purines and pyrimidines represent the fundamental requirements for their eventual assembly into nucleic acids as nucleotides and the deployment of their derivatives in other biochemical pathways. (pubmedcentralcanada.ca)