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  • asparagine
  • In 1806, French chemists Louis-Nicolas Vauquelin and Pierre Jean Robiquet isolated a compound in asparagus that was subsequently named asparagine, the first amino acid to be discovered. (wikipedia.org)
  • The conversion of aspartate into either the storage amino acid asparagine or aspartate family amino acids may be subject to a coordinated, reciprocal metabolic control, and this biochemical branch point is a part of a larger, coordinated regulatory mechanism of nitrogen and carbon storage and utilization. (wikipedia.org)
  • Chen H, Pan YX, Dudenhausen EE, Kilberg MS. Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized histone acetylation. (wikipedia.org)
  • Enzymes
  • The metabolic regulation of expression of an Arabidopsis thaliana aspartate kinase/homoserine dehydrogenase (AK/HSD) gene, which encodes two linked key enzymes in the biosynthetic pathway of aspartate family amino acids has been studied. (wikipedia.org)
  • Membrane transporters Transcription factors from the basic region/leucine zipper (bZIP) superfamily Growth factors Metabolic enzymes PCAF is recruited specifically to the CHOP amino acid response element (AARE) to enhance the ATF4 transcriptional activity. (wikipedia.org)
  • The enzymes vary considerably in structure although they all perform the same type of reaction by binding ATP, one specific amino acid and its corresponding tRNA. (wikipedia.org)
  • racemization
  • When an organism dies, control over the configuration of the amino acids ceases, and the ratio of D to L moves from a value near 0 towards an equilibrium value near 1, a process called racemization. (wikipedia.org)
  • The rate at which racemization proceeds depends on the type of amino acid and on the average temperature, humidity, acidity (pH), and other characteristics of the enclosing matrix. (wikipedia.org)
  • These are important for amino acid dating because racemization occurs much faster in warm, wet conditions compared to cold, dry conditions. (wikipedia.org)
  • Data from the geochronological analysis of amino acid racemization has been building for thirty-five years. (wikipedia.org)
  • Verification of radiocarbon and other dating techniques by amino acid racemization and vice versa has occurred. (wikipedia.org)
  • Amino acid racemization also has a role in tissue and protein degradation studies, particularly useful in developing museum preservation methods. (wikipedia.org)
  • Therefore the contribution of amino acid racemization (AAR) to understanding past climate changes is twofold: it can be used either as a geochronological tool, to reconstruct the timing of major climatic events, or (less commonly) as a paleothermometer in the case of. (springer.com)
  • Low-latitude glacial cooling in the Southern Hemisphere from amino-acid racemization in emu eggshells. (springer.com)
  • Collins M., Demarchi B. (2015) Amino Acid Racemization, Paleoclimate. (springer.com)
  • codons
  • These atypical amino acids are particularly common in organelles such as mitochondria and are encoded in variants of the standard genetic code , such as amber codons . (conservapedia.com)