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Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationMass SpectrometrySpectrometry, Mass, Electrospray IonizationTandem Mass SpectrometryPhenindioneChromatography, LiquidLasersChromatography, High Pressure LiquidProteomicsGentisatesElectrophoresis, Gel, Two-DimensionalMolecular Sequence DataGas Chromatography-Mass SpectrometryProteomeSocieties, MedicalAmino Acid SequencePeptide MappingProtein Array AnalysisPeptidesCarbohydrate SequenceCoumaric AcidsSpectrometry, Mass, Secondary IonReproducibility of ResultsSensitivity and SpecificitySpectrometry, Mass, Fast Atom BombardmentAnalytic Sample Preparation MethodsOligosaccharidesTrypsinIndicators and ReagentsPeptide FragmentsPolysaccharidesCalibrationMolecular StructureAtmospheric PressureIonsProteinsExtracellular MatrixFourier AnalysisMolecular WeightAfrican AmericansCarbohydrate ConformationMicrochemistrySocieties, ScientificGlycosylationElectrophoresis, Polyacrylamide GelMedical OncologyReference StandardsHydrolysisAir IonizationTrifluoroacetic AcidChromatography, Thin LayerCattleBiological MarkersElectrophoresis, CapillaryIsotope LabelingBlood ProteinsMagnetic Resonance SpectroscopyDeuteriumTime FactorsSequence AnalysisComplex MixturesSiliconMolecular ImagingCyclotronsNanotechnologyBacterial ProteinsProtein BindingRecombinant ProteinsTumor Markers, BiologicalUnited StatesProtein Processing, Post-TranslationalBacteriological TechniquesHydroxybenzoatesSpecimen HandlingGlycosphingolipidsGasesSocietiesCME-CarbodiimideAlgorithmsMycologyHydroxybenzoate EthersGlycomicsGlycopeptidesBinding SitesTwo-Dimensional Difference Gel ElectrophoresisBase SequenceBrachyuraGoldSpectrophotometry, UltravioletSequence Analysis, ProteinBrain ChemistrySequence Homology, Amino AcidModels, MolecularAdsorptionLasers, Solid-StateModels, ChemicalIsomerismLipid AHydrogen-Ion ConcentrationCysteine
RAPID COMMUNICATIOIdentified by MALDI-TOF mass spectrometrySecondary Ion Mass SpeInternational Journal of MMALDI Mass SpectrometryImaging Mass SpectrometryProteinsSpectroscopy2023SpectrometerProceedingsDetectionPeptidesHPLCIsolatesSpatial distributionYeastMethodsPeptide2022RRNAYeastsExperimentalProtein complexesSpectraMolecular massReactionInsightsStructuralQuadrupoleChemical SocietyAnalysisPolymerDetectorPublicationSpeciesIdentificationTimeSystemAssociationAbstract
RAPID COMMUNICATIO1
  • Chunchi Lin, Wei-Ting Hung, Chung-Hsuan Chen , Jim-Min Fang and Wen-Bin Yang, 2010, "A new naphthimidazole derivative for saccharide labeling with enhanced sensitivity in mass spectrometry detection", RAPID COMMUNICATIONS IN MASS SPECTROMETRY , 24(1), 85-94. (sinica.edu.tw)
Identified by MALDI-TOF mass spectrometry1
  • The yeasts were identified by MALDI-TOF mass spectrometry (MS). For all isolates, we performed phospholipases and proteinases assays, in vitro adherence to buccal epithelial cells (BEC), minimum inhibitory concentration of antifungal drugs and determined the cytokine profile by Cytometric Bead Array flow citometry assay. (biomedcentral.com)
Secondary Ion Mass Spe1
  • In the interest of more thoroughly understanding the relationship between sample preparation technique and spectra quality produced in Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry, we have investigated details of the Electrospray (ES) process of sample preparation by observing sample morphology with Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM) and Matrix-Enhanced Secondary Ion Mass Spectrometry (MESIMS). (nist.gov)
International Journal of M2
  • International Journal of Mass Spectrometry and Ion Processes. (wisc.edu)
  • Wang, Y.-S., 2010, "Ionizing nonvolatile samples using laser desorption-proton-transfer reaction with cluster reagent ions", International Journal of Mass Spectrometry , 291 (1-2), 61-66. (sinica.edu.tw)
MALDI Mass Spectrometry4
  • Here, we have investigated the suitability of Lys-N proteolysis for use with MALDI mass spectrometry to characterize the yeast Arp2 complex and E. coli PAP I protein interactions. (princeton.edu)
  • Overall, this Lys-N/guanidination integrative approach is applicable for functional proteomic studies utilizing MALDI mass spectrometry analysis, as it provides an effective and economical mean for relative quantification of proteins in conjunction with increased sensitivity of detection and fragmentation efficiency. (princeton.edu)
  • this was followed by MALDI mass spectrometry (MS), which showed the presence of six or fewer resolved protein components above 20 kDa in each RP-HPLC fraction, giving a total of 93 MS resolved peaks. (unboundmedicine.com)
  • After sampling a nearly microscopic piece of the leather, the chemists process it with matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to determine the unique distribution of certain peptide masses in collagen. (acs.org)
Imaging Mass Spectrometry1
  • Herein, we reported a novel method to display the in situ spatial distribution of label-free monodispersed type III rotaxane dendrimers (RDs) G1 (first generation, size ∼1.5 nm) and G2 (second generation, size ∼5 nm) that were explored as potential drug vehicles in spleen tissue by using matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-MSI). (edu.hk)
Proteins7
Spectroscopy2
  • The team plans to work closely with EMSL researchers over the next two years to utilize advanced methodologies such as Matrix Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS), Energy Dispersive X-ray Spectroscopy (EDS), and X-ray Computed Tomography (XCT). (rebeccalybrand.com)
  • Structural analysis of phototransformed C-60 by vibrational and mass spectroscopy. (mpg.de)
20231
  • Cassie and Maddie were able to attend the 2023 Soil Science Society of America International Annual Meeting, located in St. Louis, Missouri! (rebeccalybrand.com)
Spectrometer8
  • The system is built for and tested on ultrafleXtreme MALDI-TOF/TOF mass spectrometer. (cabbi.bio)
  • A variety of mass spectrometer types, including magnetic sector, quadrupole, time-of-flight, and ion trap, have and will continue to deepen our understanding of the formation and evolution of exploration targets like the surfaces and atmospheres of planets and their moons. (frontiersin.org)
  • Peptide maps of tryptic digests of HPLC fractions were obtained from a tandem quadrupole time-of-flight mass spectrometer (MALDI QqTOF MS) and were submitted to the ProFound search engine. (unboundmedicine.com)
  • Single quadrupole mass spectrometer is used for fragment spectra for volatile compounds. (coremarketplace.org)
  • Mass spectrometer that is designed for automated protein identification and characterization, biomarker detection, oligonucleotide quality control, and SNP genotyping. (coremarketplace.org)
  • Benchtop Q-Tof mass spectrometer for small molecule accurate mass determination (HRMS), intact protein analysis, and peptide mapping. (coremarketplace.org)
  • Tandem Mass Spectrometry is a technique that utilizes more than one mass selective stage in a mass spectrometer. (coremarketplace.org)
  • Synapt G2 Mass Spectrometry (MS) system is a hybrid, quadrapole/orthogonal acceleration, time-of-flight (oa-TOF) mass spectrometer controlled by MassLynx software. (coremarketplace.org)
Proceedings4
  • Proceedings of the National Academy of Sciences of the United States of America. (wisc.edu)
  • Giudicessi SL, Salum ML, Martínez-Ceron MC, Cascone O. Erra-Balsells R. Camperi SA En: Peptides 2015 Proceedings of the Twenty-Fourth American Peptide Symposium 131-133. (conicet.gov.ar)
  • Cascone O One-Bead- En: Peptides 2015 Proceedings of the Twenty-Fourth American Peptide Symposium131-133. (conicet.gov.ar)
  • Proceedings of the National Academy of Sciences of the United States of America , 107(37), 16125-16130. (sinica.edu.tw)
Detection4
  • Modern flight-capable mass spectrometers, in combination with various sample processing, separation, and ionization techniques enable sensitive detection of chemical biosignatures. (frontiersin.org)
  • Here, we delve into the search for extraterrestrial chemical and morphological biosignatures and examine several possible approaches to agnostic life detection using mass spectrometry. (frontiersin.org)
  • Recent improvement in sample preparation for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and MALDI-MS/MS provides an alternative approach for in situ drug detection. (johnshopkins.edu)
  • The identity of the drugs was further confirmed by MS/MS. Careful matrix selection and tissue preparation allows for the successful detection of drugs and the mapping of their relative abundance across various regions of the brain. (johnshopkins.edu)
Peptides1
HPLC1
Isolates2
  • Sixteen isolates were identified by DNA sequencing and 39 by matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry. (cdc.gov)
  • We evaluated Bruker Biotyper (version 2.0) matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (MS) for the identification of 305 clinical isolates of staphylococci, streptococci, and related genera by comparing direct colony testing with preparatory extraction. (elsevierpure.com)
Spatial distribution1
  • Mass spectrometry imaging (MSI) has been used to study the spatial distribution of lipid C═C location isomers in tissue sections. (edu.hk)
Yeast2
  • Environmental or physiologic parameters including the availability of oxygen, different nutrients, yeast cell density, or growth phase revealed small differences in the peptide mass fingerprint. (asbcnet.org)
  • The status of a spoilage yeast performing fermentation or respiration could be precisely differentiated along these small differences (biomarkers) in the mass spectrum. (asbcnet.org)
Methods4
  • The stoichiometry and structure of the newly formed metal quinolinolate-fullerene complexes were established from various spectroscopic methods including matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and computational density functional theory studies. (ewha.ac.kr)
  • Comparison of phenotypic methods and matrix-assisted laser desorption ionisation time-of-flight mass spectrometry for the identification of aero-tolerant Actinomyces spp. (medscape.com)
  • Time-of-Flight Mass Spectrometry," won in the category of Laboratory and Methods. (cdc.gov)
  • Comparison of Different Methods for the Determination of the Molecular Mass and Molecular Mass Distribution of Poly(ethylmethylsiloxane). (mpg.de)
Peptide3
  • American Peptide Society. (conicet.gov.ar)
  • Matrix assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) could deliver discriminative peptide mass fingerprints within minutes and could thus be a rapid and reliable tool for the identification and differentiation of beverage spoiling yeasts. (asbcnet.org)
  • To verify claims of human epidermal bindings, Kirby and his colleagues use peptide mass fingerprinting. (acs.org)
20221
  • According to the American Cancer Society, there were about 54,000 new cases of and about 11,230 deaths from oral cavity or oropharyngeal cancer in 2022. (medscape.com)
RRNA3
  • S. halichoeri tests positive for Lancefield group B antigen, like S. agalactiae , but can be identified with matrix-assisted laser desorption/ionization time of flight mass spectrometry or partial 16S rRNA sequencing. (cdc.gov)
  • We used 3 different approaches: biochemical testing, matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry, and 16S ribosomal RNA (rRNA) gene sequencing. (medscape.com)
  • A concordant identification of P. multocida was observed using biochemical testing, mass spectrometry, and 16S rRNA gene sequencing. (medscape.com)
Yeasts1
  • Currently she is working on her Ph.D. thesis on the ability to detect beverage spoiling yeasts using MALDI-TOF mass spectrometry at Technische Universität München under the supervision of Rudi F. Vogel at the Chair of Technische Mikrobiologie in Weihenstephan. (asbcnet.org)
Experimental2
  • Experimental results indicated that the trans-2-[3-(4-tert-butylphenyl)-2-methyl-2-propenylidene]malononitrile (DCTB) matrix exhibited the best performance for monodispersed type III RDs G1 and G2. (edu.hk)
  • Herein, we established an on-tissue charge-switching Paternò-Büchi (PB) derivatization method using 3-acetylpyridine (3-AP) as a reaction reagent, which can be used to detect and assign C═C location of glycerophospholipids (GPLs) as well as neutral lipids, such as fatty acids (FAs), under the same experimental workflow using matrix-assisted laser desorption/ionization (MALDI)-MSI. (edu.hk)
Protein complexes1
Spectra1
  • MALDI matrixes were applied directly to 14-μm brain cryosections and spectra acquired. (johnshopkins.edu)
Molecular mass1
  • Our investigations demonstrate improvements in the precision of MALDI average molecular mass measurements attributed to use of the ES sample preparation technique. (nist.gov)
Reaction1
  • The effects that working variables have on the kinetics of the reaction, such as temperature, feed ratio, molar mass of the polymer and the introduction of an amorphous block in the polymer structure, have been investigated. (unav.edu)
Insights2
  • E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A) . Biochemistry , 41 (50), 15025-1535. (uea.ac.uk)
  • For the past fifty years of space exploration, mass spectrometry has provided unique chemical and physical insights on the characteristics of other planetary bodies in the Solar System. (frontiersin.org)
Structural2
  • AXE STRUCTURAL**- Le progrès des connaissances dans ce domaine nécessite de lever des verrous analytiques en particulier pour la caractérisation structurale et le séquençage de séquences glucidiques bioactives, dont les méthodes font aujourd'hui encore défaut. (hal.science)
  • Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry Nature Communications, 13(), 5884. (coremarketplace.org)
Quadrupole1
  • Combines quadrupole, ion trap, and Orbitrap mass analysis into Tribrid architecture to provide depth of analysis. (coremarketplace.org)
Chemical Society3
  • Journal of the American Chemical Society. (wisc.edu)
  • Presented at the 68th Southeast Regional Meeting of the American Chemical Society, Columbia, SC. (ncsu.edu)
  • Journal of the American Chemical Society , 130 (50), 16959-16967. (ewha.ac.kr)
Analysis3
  • macroMS: Image-Guided Analysis of Random Objects by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. (cabbi.bio)
  • The American Hospital Association (the "AHA") has not reviewed, and is not responsible for, the completeness or accuracy of any information contained in this material, nor was the AHA or any of its affiliates, involved in the preparation of this material, or the analysis of information provided in the material. (cms.gov)
  • Quantitative analysis of broad molecular weight distributions obtained by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry. (mpg.de)
Polymer2
  • The molar mass of the polymer does not modify the typical channel-like arrangement of packed PPRs but the conversion into crystalline PPR diminishes when using PEG1000 instead of PEG400. (unav.edu)
  • Why does matrix-assisted laser desorption/ionization time-of-flight mass spectrometry give incorrect results for broad polymer distributions? (mpg.de)
Detector1
Publication1
  • No portion of the American Hospital Association (AHA) copyrighted materials contained within this publication may be copied without the express written consent of the AHA. (cms.gov)
Species1
  • MALDI-TOF mass spectrometry can be used to identify species of mycobacteria, like those that cause tuberculosis. (cdc.gov)
Identification3
  • Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. (medscape.com)
  • Still a core of mass peaks remained constant under all tested conditions enabling reliable identification. (asbcnet.org)
  • Cleancatch, unpreserved urine samples from children aged 216Dx, and positive urine samples in media were processed for direct bacterial identification by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry. (childrensmercy.org)
Time3
  • A rapid matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for single-plasmid tracking in an outbreak of carbapenem-resistant Enterobacteriaceae. (nih.gov)
  • Here, we demonstrate that real-time, direct tracking of a single plasmid in a bacterial strain responsible for an outbreak is possible using a commercial matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) system. (nih.gov)
  • In the current study, we used matrix-assisted laser desorption ionization time of flight mass spectrometry to identify pasteurized bovine milk-associated mesophilic and psychrotrophic bacteria. (huji.ac.il)
System1
  • An important impetus for the continuing exploration of Mars, Europa, Enceladus, Titan, and Venus involves assessing the habitability of solar system bodies and, ultimately, the search for life-a monumental effort that can be advanced by mass spectrometry. (frontiersin.org)
Association2
  • and/or making any commercial use of UB‐04 Manual or any portion thereof, including the codes and/or descriptions, is only authorized with an express license from the American Hospital Association. (cms.gov)
  • In the United States, according to the 2015-2016 American Pet Products Association (APPA) National Pet Owners Survey, 65% of United States (US) households own a pet, which translates to approximately 77.8 million pet dogs and 85.8 million pet cats. (medscape.com)
Abstract1