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  • epithelial
  • Within the fibrous tissue there is an ameloblastoma comprising fragments of a peripherally pallisaded and focally basaloid appearing epithelial lining of columnar cells with hyperchromatic nuclei with focal areas demonstrating reverse polarity along the basal layer of epithelium. (radiopaedia.org)
  • Jaws
  • I. A. Small and C. A. Waldron, "Ameloblastoma of the Jaws," Journal of Oral and Maxillofacial Surgeryand Pathology , vol. 8, pp. 281-297, 1995. (hindawi.com)
  • enucleation
  • While chemotherapy, radiation therapy, curettage and liquid nitrogen have been effective in some cases of ameloblastoma, surgical resection or enucleation remains the most definitive treatment for this condition. (wikipedia.org)
  • mutation
  • It is a driver mutation in a proportion of certain diagnoses, including melanoma, hairy cell leukemia, papillary thyroid carcinoma, colorectal cancer, non-small-cell lung cancer, Langerhans cell histiocytosis, and ameloblastoma. (wikipedia.org)
  • Treatment
  • Tan S, Pollack JR, Kaplan MJ, Colevas AD, West RB (2016) BRAF inhibitor treatment of primary BRAF-mutant ameloblastoma with pathologic assessment of response. (springer.com)
  • Heikinheimo K, Kurppa KJ, Elenius K (2015) Novel targets for the treatment of ameloblastoma. (springer.com)
  • In a detailed study of 345 patients, chemotherapy and radiation therapy seemed to be contraindicated for the treatment of ameloblastomas. (wikipedia.org)