• Enamelysin cuts (cleaves) other proteins involved in enamel formation, such as amelogenin and ameloblastin, into smaller pieces. (medlineplus.gov)
  • The Dynamic Interactions of a Multitargeting Domain in Ameloblastin Protein with Amelogenin and Membrane. (bvsalud.org)
  • Amelogenesis imperfecta is due to the malfunction of the proteins in the enamel: ameloblastin, enamelin, tuftelin and amelogenin. (intelligentdental.com)
  • Ameloblast differentiation in these cultures was investigated by analysis of the mRNA and/or protein expression of ameloblastin and amelogenin. (elsevierpure.com)
  • The proteins responsible for amelogenesis imperfecta are enamelin, ameloblastin, amelogenin and tuftelin. (medicinelearners.com)
  • Amelogenin (AMELX) ve ameloblastin (AMBN) emaye oluşumu için çok önemlidir ve bu proteinlerin üretimindeki kesintiler emaye kusurlarına neden olabilir. (atlas.edu.tr)
  • The enamel protein matrix consists of unique enamel proteins such as amelogenin, ameloblastin, and enamelin, which are secreted by highly specialized cells called ameloblasts. (tamu.edu)
  • In addition to it, the other reasons might include a mutation in genes coding for certain proteins like enamelin ameloblastin, and amelogenin can result in altered or improper formation of enamel. (dentadigest.com)
  • Ameloblastin (abbreviated AMBN and also known as Sheathlin or Amelin) is an enamel matrix protein that in humans is encoded by the AMBN gene. (wikipedia.org)
  • The enamel matrix protein Ameloblastin (Ambn) has critical physiological functions, including regulation of mineral formation, cell differentiation , and cell -matrix adhesion. (bvsalud.org)
  • Background: Ameloblastin (AMBN) is a secreted matrix protein that is critical for the formation of dental enamel and is enamel-specific with respect to its essential functions. (ozgene.com)
  • 4q13.3) encodes a glycine, leucine, and proline-rich enamel matrix protein called ameloblastin, a second most abundant protein expressed during amelogenesis. (biomedcentral.com)
  • Ameloblastin cleavage products are found in the sheath space between rod and interrod enamel, while intact ameloblastin accumulates on the enamel rods. (wikipedia.org)
  • Ameloblastin is generally implicated in enamel development, but may also have a role in root development. (wikipedia.org)
  • Ameloblastin-rich enamel matrix favors short and randomly oriented apatite crystals. (rochester.edu)
  • Ameloblastin helps in the growth of a crystalline enameloid layer consisting of randomly oriented short enamel crystals. (wikipedia.org)
  • Conclusions: Ameloblastin is critical for the initiation of enamel ribbon formation, and its absence results in pathological mineralization within the enamel organ epithelia. (ozgene.com)
  • Moreover, histological analysis of incisor from knockout mice showed decreased ameloblastin and expedited KLK4 expression in the ameloblasts. (njit.edu)
  • Enamelysin cuts (cleaves) other proteins involved in enamel formation, such as amelogenin and ameloblastin, into smaller pieces. (medlineplus.gov)
  • 3. Tracking endogenous amelogenin and ameloblastin in vivo. (nih.gov)
  • 15. N-terminal region of human ameloblastin synthetic peptide promotes bone formation. (nih.gov)
  • 17. Bioinformatic analysis and molecular modelling of human ameloblastin suggest a two-domain intrinsically unstructured calcium-binding protein. (nih.gov)
  • 20. Intrinsically disordered enamel matrix protein ameloblastin forms ribbon-like supramolecular structures via an N-terminal segment encoded by exon 5. (nih.gov)
  • 2. Ameloblastin, an Extracellular Matrix Protein, Affects Long Bone Growth and Mineralization. (nih.gov)
  • 1. Ameloblastin as a putative marker of specific bone compartments. (nih.gov)
  • We conclude that MMP-20 processes ameloblastin in vitro and in vivo. (nih.gov)
  • 11. Ameloblastin upstream region contains structural elements regulating transcriptional activity in a stromal cell line derived from bone marrow. (nih.gov)
  • 4. The ameloblastin extracellular matrix molecule enhances bone fracture resistance and promotes rapid bone fracture healing. (nih.gov)
  • 9. Ameloblastin expression during craniofacial bone formation in rats. (nih.gov)
  • Ameloblastin helps in the growth of a crystalline enameloid layer consisting of randomly oriented short enamel crystals. (wikipedia.org)
  • 10. Critical role of heparin binding domains of ameloblastin for dental epithelium cell adhesion and ameloblastoma proliferation. (nih.gov)