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  • amyloid beta
  • For example, a vaccine might target amyloid beta, a believed precursor to tau, which exists in the brain throughout one's life but only becomes toxic with the onset of Alzheimer's. (bigthink.com)
  • However, if the amyloid beta has benefits in its non-toxic form that scientists have yet to discover, a vaccine against it could trigger a host of other problems. (bigthink.com)
  • The vaccine works by stimulating the activity of microglial cells, the body's natural nervous system defenders, which are able to attack and prevent the proliferation of amyloid beta, the toxic plaque molecules that form in the brain and largely are responsible for the progression of Alzheimer's. (everydayhealth.com)
  • vaccination
  • It would be great if at that time of birth or very short afterward if there were a vaccine, an active vaccination that will protect us," says Dr. Arancio. (bigthink.com)
  • Childhood vaccination has saved many lives, yet lots more has to be done to increase awareness and eliminate myths regarding vaccines. (medindia.net)
  • vaccinate
  • This study suggests that we can immunize patients with early stages of AD with our anti-AB vaccine and, if it progresses, then vaccinate with our anti-tau vaccine," says Dr. Michael Agadjanyan, Professor and Head of Immunology at the Institute for Molecular Medicine and faculty at the Institute for Memory Impairments and Neurological Disorders, UCI, and one of the senior authors of the study. (marketwired.com)
  • study
  • The vaccine used in that study activated certain white blood cells (T cells), which started to attack the body's own brain tissue. (psychcentral.com)
  • The results obtained indicate that the vaccine is well tolerated and that a portion of patients developed a sufficient immunological response to AN-1792 to warrant the initiation of the additional study. (prohealth.com)
  • In the phase I study, the vaccine demonstrated a good safety and tolerability profile and produced an immune response in a high percentage of patients. (biospectrumindia.com)
  • The next step after this Phase 1 safety trial should be a larger test, possibly with modifications of the dose, to see if the vaccine works, says the study. (medicalxpress.com)
  • adverse
  • 2. Unlike drugs, the Big Pharma manufacturers are not legally obligated to pay out for damages resulting from the adverse effects of vaccines. (sott.net)
  • The vaccine court establishment will only award payouts in cases involving serious adverse reactions from vaccines. (sott.net)
  • inflammation
  • Rivest says other vaccines in research stage have been ineffective, and one was found to cause inflammation of the brain. (everydayhealth.com)
  • WASHINGTON (AP) - The maker of a highly touted experimental Alzheimer's vaccine has ended development of the compound after 15 patients suffered serious brain inflammation. (sddt.com)
  • development
  • The vaccine appears to have a preventative effect - slowing the development of further tangles rather than clearing existing ones - but the exact mechanism involved is not yet understood," he says. (australasianscience.com.au)
  • advantages
  • While this treatment stands to bring in blockbuster drug revenue, there are other advantages for Big Pharma which could lead to much exploitation and manipulation for those receiving the vaccine, as will be explained later. (sott.net)
  • Before looking at those R&D sources, let's consider the advantages of having an Alzheimer's vaccine from Big Pharma's point of view. (sott.net)
  • An Alzheimer's vaccine will have a number of advantages for Big Pharma. (sott.net)