Alzheimer DiseaseNeurofibrilstau ProteinsPlaque, AtheroscleroticAmyloid beta-PeptidesDental PlaqueTauopathiesBrainAmyloid beta-Protein PrecursorDementiaNeuropil ThreadsAmyloidViral Plaque AssayApolipoprotein E4Neurofibrillary TanglesPlaque, AmyloidApolipoproteins ECognition DisordersMice, TransgenicAmyloid Precursor Protein SecretasesHippocampusAtrophyNeuronsNerve DegenerationLewy Body DiseaseDisease Models, AnimalPeptide FragmentsNeuropsychological TestsCerebral Amyloid AngiopathyCerebral CortexAgingDementia, VascularImmunohistochemistryPresenilin-1Brain ChemistryDental Plaque IndexMild Cognitive ImpairmentDiffuse Neurofibrillary Tangles with CalcificationNeurodegenerative DiseasesLewy BodiesAtherosclerosisPhosphorylationMagnetic Resonance ImagingDisease ProgressionGliosisMemory DisordersCognitionCarotid Artery DiseasesAmyloidogenic ProteinsCyclin-Dependent Kinase 5Mental Status ScheduleRupture, SpontaneousArteriosclerosisNerve Tissue ProteinsDown SyndromeAspartic Acid EndopeptidasesAniline CompoundsCarotid StenosisPresenilinsUltrasonography, InterventionalPick Disease of the BrainCarotid ArteriesCongo RedTemporal LobeMicrotubule-Associated ProteinsBiological MarkersPostmortem ChangesAge of OnsetPositron-Emission TomographyMutationInclusion BodiesSupranuclear Palsy, ProgressiveEntorhinal CortexPresenilin-2Coronary Artery DiseaseMicrogliaThiazolesMicroscopy, ElectronSeverity of Illness IndexAutopsyLongitudinal StudiesNeurofilament ProteinsGuamIntermediate FilamentsRisk FactorsAngioscopyCaspase 6Alzheimer VaccinesBoxingMolecular Sequence DataHemolytic Plaque TechniqueSolubilityCholinesterase InhibitorsTime FactorsFrontal LobeMemantineMaze LearningImage Processing, Computer-AssistedGenotypeImmunoenzyme Techniques