• Diseases of the central nervous system, including Parkinson's, Alzheimer's, and amyotrophic lateral sclerosis (ALS), are included in the scope of work. (genengnews.com)
  • It is also targeting diseases of the central nervous system, such as Parkinson's, Alzheimer's and Amyotrophic Lateral Sclerosis (ALS). (pmlive.com)
  • These disorders, which include Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis and stroke, cause loss of neural tissue and functional impairment. (ca.gov)
  • Because of the neurotropism of Lyme disease, speculative websites and articles and even peer-reviewed journals have purported causal associations between Lyme disease and several neurodegenerative disorders, including Alzheimer disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and Parkinson disease ( 6 - 11 ). (cdc.gov)
  • Although the function of AEG‑1 has been demonstrated in neurological disorders, such as Alzheimer's disease and amyotrophic lateral sclerosis, the underlying mechanism of neuronal AEG‑1 function remains unclear. (spandidos-publications.com)
  • These alterations have been described in neurodegenerative pathologies such as Alzheimer s and Parkinson s disease, amyotrophic lateral sclerosis and transmissible spongiform encephalopaties. (lu.se)
  • Additionally, the dysfunction of glial cells induces all kinds of pathologies in the nervous system like Alzheimer's and Parkinson's disease, epilepsy and multiple sclerosis. (edu.sa)
  • Here, the latest insights into the function of Wnt signalling in the adult nervous system and therapeutic opportunities for neurodegenerative diseases such as Alzheimer's and Parkinson's disease are discussed. (nih.gov)
  • Working with the university's Office of Technology Commercialization, he's filed a patent application for the worm model for testing of neurodegenerative diseases such as Alzheimer's and Parkinson's. (neurosciencenews.com)
  • Yes, age-associated diseases such as cancer and cardiovascular disease are clearly bad, but the most devastating of these involve the nervous system-diseases like Alzheimer's and Parkinson's. (sentientdevelopments.com)
  • He has joined Juan Gonzalez, MD , at HPG-Neurology and diagnoses and treats issues related to the brain, spinal cord, nerves and muscles, including the treatment of Alzheimer's and Parkinson's disease, seizure disorders, and strokes. (hamiltonhealth.com)
  • A structural component of brain cells, tau has also been linked to Alzheimer's and Parkinson's diseases. (medlineplus.gov)
  • Alzheimer's, Parkinson's, and Huntington's diseases). (wikipedia.org)
  • Possible treatment for Alzheimer's disease and other neurodegenerative diseases ( Parkinson's disease , Huntington's disease , etc. (iptq.com)
  • The mis-folding of protein is considered to be the cause of many degenerative diseases that affect the nervous system, including Alzheimer's, Parkinson's and Huntington's disease. (nutraingredients.com)
  • According to the lab: "These imaging agents are used for diagnosing early-stage neurological disorders and assessing disease progression, as well as monitoring the therapeutic efficacy of treatment for CNS (central nervous system) disorders including Alzheimer's disease, Parkinson's disease, Huntington's disease, and schizophrenia. (owu.edu)
  • In addition, AEG-1 as a key modulator regulates aberrant cellular processes within the central nervous system (CNS), where it is involved in neurological diseases such as Huntington's chorea, migraine and HIV-induced neurological disorders ( 7-9 ). (spandidos-publications.com)
  • MINNEAPOLIS - A drug that would be the first to target the cause of Huntington's disease (HD) is effective and safe when tested in mice and monkeys, according to data released today that will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016. (eurekalert.org)
  • Huntington's disease is a rare, hereditary disease that causes uncontrolled movements, loss of intellectual abilities, emotional problems and eventually death. (eurekalert.org)
  • The new drug, called IONIS-HTTRx, is an antisense drug that acts as a "gene silencer" to inhibit the production of huntingtin protein in people with Huntington's disease. (eurekalert.org)
  • Earlier studies in mouse models of Huntington's disease showed that treatment with antisense drugs delays disease progression and results in sustained reversal of the disease phenotype. (eurekalert.org)
  • The ongoing clinical study is supported by Ionis Pharmaceuticals and is part of Ionis' collaboration with Roche to develop antisense drugs to treat Huntington's disease. (eurekalert.org)
  • Learn more about Huntington's disease at http://www.aan.com/patients . (eurekalert.org)
  • To check flow of blood to the brain, which can help doctors to trace and treat nervous system problems like Parkinson's disease, Alzheimer's disease, Huntington's disease, transient ischemic attack (TIA), stroke, schizophrenia, multiple sclerosis and amyotrophic sclerosis (ALS). (medicalhealthtests.com)
  • And I've spent my life looking at cel therapies and other therapeutic approaches to two diseases, Parkinson's disease and Huntington's disease. (lu.se)
  • Supported by this facility, we have in the past year successfully developed a process for the production of functional dopaminergic neurons from hESCs that are suitable for potential clinical uses, e.g., in treating Parkinson's disease (Parkinson's disease is caused by the death of dopaminergic neurons). (ca.gov)
  • Central nervous system diseases, also known as central nervous system disorders, are a group of neurological disorders that affect the structure or function of the brain or spinal cord, which collectively form the central nervous system (CNS). (wikipedia.org)
  • Johns Hopkins Medicine: "Overview of Nervous System Disorders. (webmd.com)
  • Historically, disorders of taste and smell have been difficult to diagnose and treat, often because of a lack of knowledge and understanding of these senses and their disease states. (medscape.com)
  • Agid is both a medical doctor and a scientist, and his laboratory is devoted to the treatment of patients with neurodegenerative disorders such as Alzheimer's or Parkinson's disease. (edu.sa)
  • A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, migraine, multiple sclerosis, concussion, Parkinson's disease and epilepsy. (eurekalert.org)
  • Help diagnose a variety of neurological problems - from headaches and dizziness to seizure disorders, strokes, degenerative brain disease and sleep disorders. (jccc.edu)
  • Know how to analyze and monitor the nervous system in patients with epilepsy, Parkinson's disease, Alzheimer's disease, and seizure disorders. (jccc.edu)
  • This scan is mainly used in the determination of the nervous system disorders as in Alzheimer's disease and Parkinson's disease. (differencebetween.net)
  • We hypothesized that, if there is a link between B. burgdorferi infection and subsequent development of Alzheimer disease, ALS, MS, or Parkinson disease, the geographic distribution of these neurodegenerative disorders should correlate with that of Lyme disease. (cdc.gov)
  • To determine if such a correlation exists, we compared the distribution of confirmed cases of Lyme disease in the United States with the distribution of deaths due to these 4 neurodegenerative disorders. (cdc.gov)
  • We used the Moran's I test for spatial autocorrelation to assess geographic clustering of state incidence rates of Lyme disease and of death rates for the 4 neurologic disorders by using ArcGIS 10.1 (ESRI, Redlands, CA, USA). (cdc.gov)
  • This also includes the potentially disease-causing proteins that collect in the cells of patients with neurodegenerative disorders - for example, beta amyloids that agglomerate to form long fibrils in the nerve cells of Alzheimer's patients. (tum.de)
  • Heat shock proteins are also associated with other nervous system disorders like Parkinson's disease and multiple sclerosis. (tum.de)
  • Thus, we invite investigators to contribute brief and original articles on neurodegenerative diseases via multiple bioactivities and the potential therapeutic effects of medicinal herbs on these disorders. (hindawi.com)
  • Tetra Therapeutics , a Shionogi Group Company, is a clinical-stage biotechnology company focused on developing a portfolio of therapeutic products for people suffering from Fragile X syndrome, Alzheimer's disease, traumatic brain injury, and other brain disorders. (fragilex.org)
  • Our work with MJFF underscores our unwavering commitment to delivering new medications for neurological disorders characterized by deposits of misfolded proteins, including both Parkinson's and Alzheimer's diseases. (anavex.com)
  • On the other hand, long-term inflammation of the brain is a condition factored in as the main cause of central nervous system disorders like Parkinson's and Alzheimer's disease. (mbtitoday.org)
  • It is dedicated to diseases of the brain and nervous system, such as Alzheimer's, Parkinson's, and ALS, which are associated with dementia, movement disorders and other serious health impairments. (dzne.de)
  • Overview of Movement Disorders Every body movement, from raising a hand to smiling, involves a complex interaction between the central nervous system (brain and spinal cord), nerves, and muscles. (msdmanuals.com)
  • Neurological disorders affecting the central and peripheral nervous system, most frequently reported in primary care include headache, epilepsy, cerebro-vascular disorders, neuropathies, infectious disorders, Alzheimer's disease and other forms of dementia, and Parkinson's disease. (who.int)
  • It has been studied in pathologies such as Alzheimer's disease, Parkinson's disease, and convulsive disorders. (bvsalud.org)
  • The nervous system wracked with tertiary syphilis, causing dementia and paralysis. (iptq.com)
  • Age-related dementia constitutes a major subset of neurodegenerative disease. (hindawi.com)
  • Alzheimer's disease (AD) is the most prevalent clinical form of dementia in aging populations, and 43% of individuals aged ≥ 85 years are thought to have AD in the United States. (hindawi.com)
  • Dementia is not a specific disease but is rather a general term for the impaired ability to remember, think, or make decisions that interferes with doing everyday activities. (roche.com)
  • Advances in biomarker testing, a growing number of dementia-inclusive communities, and open clinical trials for conditions like Alzheimer's disease are transforming future outlooks. (roche.com)
  • Available from: URL: http://www.cdc.gov/pcd/ ture this additional dementia data and ensure a repre- issues/2004/jan/03_0011.htm sentative system. (cdc.gov)
  • Prevalence of dementia is expected to increase three- to DOH) Alzheimer's Disease and Other Dementias Registry four-fold in the next 50 years. (cdc.gov)
  • Completeness may be itself as well as the health-related event under surveil- undermined when hospitals and nursing homes fail to lance (dementia), and gathering evidence on the perform- report data, and hospital charts do not record dementia ance of the surveillance system. (cdc.gov)
  • cians, and other stakeholders, a bill establishing the Hospitals and nursing homes document dementia and Alzheimer's Disease and Other Dementias Registry comorbidities more effectively among frail individuals and became law in 1986. (cdc.gov)
  • Neuroscientists are not only fascinated by this astonishing speed, but they also recognize that disturbing the speed of synaptic transmission has deleterious consequences on brain function and can lead to various diseases of the nervous system including schizophrenia, depression, Parkinson's disease, epilepsy and Alzheimer's disease. (sciencedaily.com)
  • Dedicates $1.5 billion to fund research and therapy for Alzheimer's, Parkinson's, stroke, epilepsy, and other brain and central nervous system diseases and conditions. (fremontbusiness.com)
  • Within this group, epilepsy is refractory in up to 40 % of patients, who have shown para el control de síntomas refractarios en a decrease in the frequency of seizures with the concomitant use of cannabidiol and conventional antiepileptics, with mild síndromes convulsivos side effects such as diarrhea and drowsiness. (bvsalud.org)
  • As a potential platform drug and the Company's lead therapeutic, ANAVEX 2-73 targets misfolded proteins central to many neurodegenerative diseases, including Parkinson's and Alzheimer's. (anavex.com)
  • Our system provides a path to a scalable Good Manufacture Practice (GMP)-applicable process of generation of dopaminergic neurons from hESCs for therapeutic applications, and a ready source of large numbers of neurons for potential drug screening applications. (ca.gov)
  • Blocking the release or activation of extracellular HMGB1 has been proposed as a promising therapeutic target for inflammatory diseases. (frontiersin.org)
  • Maltol has potential as a new neuroprotective therapeutic agent for oxidative stress-related ocular diseases, including glaucoma. (molvis.org)
  • Further investigation into this exciting field promises to shed insights into the mechanisms of health and disease and provide new therapeutic options. (medscape.com)
  • We standardized the Lyme disease incidence rates and neurodegenerative disease death rates to the 2000 US population by using 10-year age groups ( http://www.census.gov/2000census/data/ ). (cdc.gov)
  • The United Nations population projections have estimated a worldwide population of 400 million individuals aged ≥ 80 years by 2050 to have a neurodegenerative disease. (hindawi.com)
  • However, while misfolded protein aggregation clearly plays a role in neurodegenerative disease, this is evidently only a signature of neuronal damage and additional causative factors remain to be discerned. (hindawi.com)
  • Astrocyte elevated gene‑1 (AEG‑1) is a key regulatory factor of progression in multiple types of tumor and neurodegenerative disease development. (spandidos-publications.com)
  • In AST, AEG-1 causes glutamatergic excitotoxicity by downregulating the activity of the excitatory amino acid transporter 2 (EAAT2) promoter, leading to neuronal cell death in glioma-induced neurodegenerative disease ( 10 ). (spandidos-publications.com)
  • As the disease progresses and dopaminergic neurons continue to be lost, these drugs eventually become less effective at treating the symptoms. (anavex.com)
  • The central nervous system (CNS) is a complex, sophisticated network of neurons that includes our brain and spinal cord. (roche.com)
  • Yeah, the idea is based on the possibility to replace the lost dopamine neurons with new cel s that would take over the function from the cel s that are lost to the disease. (lu.se)
  • Reactive glial cells secrete a wide variety of signaling molecules in response to neuronal perturbations and thus play a crucial role in the progression and regulation of central nervous system (CNS) injury. (cdc.gov)
  • This narrative article aims to determine the use of cannabidiol for the control of Current therapy for advanced diseases is refractory neurological symptoms in patients oriented towards symptom control rather with seizure syndromes and neurode- than halting their progression. (bvsalud.org)
  • METHOD: Both genetic and functional alterations in mitochondria can lead to errors that trigger programmed cell death, which in turn give rise to a number of diseases that affect the nervous system. (lu.se)
  • Early symptoms of the disease include shaking, rigidity, and slowness of movement. (neurosciencenews.com)
  • Right now we only have treatments that work on the symptoms of the disease. (eurekalert.org)
  • Current Parkinson's treatments are only effective in managing symptoms of the disease, mainly through the use of levodopa and dopamine agonists. (anavex.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • Age-adjusted death rates of Alzheimer disease, ALS, MS, and Parkinson disease during the same time period were obtained from the CDC WONDER (Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research) database ( http://wonder.cdc.gov/WelcomeT.html ). (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • The National Center for Chronic Disease Prevention and Health Promotion at the Centers for Disease Control and Prevention funds the agency's largest investment in Indian Country, Good Health and Wellness in Indian Country. (cdc.gov)
  • This program identified approaches useful for the Centers for Disease Control and Prevention, other federal agencies, or other organizations working with American Indians and Alaska Natives. (cdc.gov)
  • This project aimed at increasing and assessing awareness of risk, symptoms, and recommended screenings and prevention activities in underserved women, through unique collaboration between the Centers for Disease Control and Prevention's (CDC) Inside Knowledge (IK) campaign, which was designed to educate women about gynecologic cancer, and the CDC's national network of organizations to reduce cancer-related disparities. (cdc.gov)
  • Oxygen radicals are also implicated in cardiovascular disease and in age-related nerve cell damage. (i-sis.org.uk)
  • Ross and Kasum [5] listed studies that support a protective effect of flavonoids in cardiovascular disease and cancer but indicated that other studies showed no effect and a few studies suggested potential harm. (i-sis.org.uk)
  • Background: Understanding and addressing cardiovascular disease (CVD) risk has implications for maternal and child health outcomes. (cdc.gov)
  • Problems with the body's immune system can lead to tumors. (wikipedia.org)
  • Inflammation is a natural process that occurs when the body's immune system responds to injury or infection. (wlnaturalhealth.com)
  • In addition to working with partners to develop novel first-in-class medicines, Bactevo is also developing breakthrough medicines for the treatment of diseases that involve defects in mitochondrial function, such as MELAS and LHON. (pmlive.com)
  • Oxidative stress is known to involve in the pathogenesis and development of many diseases in the central nervous system. (purdue.edu)
  • An autoimmune disorder is a condition where in the immune system attacks and destroys healthy body tissue. (wikipedia.org)
  • In this dissertation, we also indicated that acrolein could induce hypersensitivity to pain stimuli and involved in the neuropathic pain post neurotrauma or accompanying with an autoimmune demyelinated disease Multiple Sclerosis. (purdue.edu)
  • MS is an autoimmune disease that affects the central nervous system. (medlineplus.gov)
  • Scientific evidence and research supporting CBD oil's anti-inflammatory properties, as well as its potential applications for arthritis, inflammatory bowel disease, skin conditions, and neuroinflammation. (wlnaturalhealth.com)
  • The mechanism of CBD oil in reducing inflammation, including its interaction with the endocannabinoid system and inhibition of inflammatory cytokines and pathways. (wlnaturalhealth.com)
  • Chronic inflammation is characterized by a persistent immune response that can lead to tissue damage and contribute to the development of various diseases, including arthritis, inflammatory bowel disease, and cardiovascular conditions. (wlnaturalhealth.com)
  • To understand how CBD oil can potentially reduce inflammation, we must explore its interaction with the endocannabinoid system (ECS). (wlnaturalhealth.com)
  • When Mechoulam and colleagues isolated THC in 1964, they made it possible to further understand the complex nature of the endocannabinoid system. (medscape.com)
  • In the 21st century, new discoveries of other endocannabinoids, their site distributions, and roles are deepening our understanding of the endocannabinoid system. (medscape.com)
  • However, Wanker and his team explained that it remains to be seen whether O4 can also be effective against small amounts of misfolded proteins in the brains of Alzheimer's patients, and whether the accelerated formation of larger plaques can indeed reduce the signs and symptoms of Alzheimer's disease in humans. (nutraingredients.com)
  • It's the loss of dopamine-producing cells in the brain that causes Parkinson's disease in humans. (neurosciencenews.com)
  • Pierce-Shimomura says that although humans have a vastly more complex nervous system than the worms, the two species share an "ancient and conserved" genetic structure to their dopaminergic systems. (neurosciencenews.com)
  • It is assumed, they noted, that small mis-folded protein aggregates - that are the precursors to larger mature plaques - are toxic to nerve cells, thus leading to the destruction of nerve cells and a decline in cognitive and/or central nervous functioning. (nutraingredients.com)
  • Disturbingly, many cognitive changes occur even in the absence of specific age-related neurodegenerative diseases. (sentientdevelopments.com)
  • Age-associated cognitive decline is currently costing the healthcare system a third of a trillion dollars per year. (sentientdevelopments.com)
  • The diagnosis of central nervous system disease is largely based on clinical symptoms and cognitive testing. (roche.com)
  • From informing lifestyle changes that could help to slow the decline in cognitive functions to optimizing treatment, biomarker testing is opening new opportunities for people with CNS disease. (roche.com)
  • 1992. Auditory event-related potential (P300) in relation to peripheral nerve conduction in workers exposed to lead, zinc, and copper: Effects of lead on cognitive function and central nervous system. (cdc.gov)
  • Transglutaminase is bad for the ocular system. (naturalpedia.com)
  • Transglutaminase is bad for the nervous, cardiovascular, and ocular systems. (naturalpedia.com)
  • Infectious diseases are transmitted in several ways. (wikipedia.org)
  • The study was funded by the National Institute of Allergy and Infectious Diseases. (medlineplus.gov)
  • The study was funded in part by the National Institute of Allergy and Infectious Diseases and the National Institute of Mental Health. (medlineplus.gov)
  • Generally, an infection is a disease that is caused by the invasion of a microorganism or virus. (wikipedia.org)
  • Central nervous system infection resulting in early neurologic Lyme disease, and more rarely late neurologic Lyme disease, is well documented ( 4 , 5 ). (cdc.gov)
  • Multiple signaling pathways constitute the molecular basis of the effects of genetic variation, lifestyle, and environmental factors including trauma and infection in neurodegenerative diseases. (hindawi.com)
  • In a story very similar to the discovery of opiate receptors in the brain, cannabinoid receptors have been discovered along with their endogenous cannabinoids, representing the largest neurotransmitter system in the brain and immune system. (greenmedinfo.com)
  • It seemed likely that something similar was happening with THC and the cannabinoid receptors in the brain and the immune system. (greenmedinfo.com)
  • This review highlights the research focusing on the direct interaction between the immune system and the toxicant- or occupational injury-induced gliosis. (cdc.gov)
  • Running multiple assays in parallel, it harnesses next-generation synthetic bio-space libraries, identifies disease networks, and targets and deploys chem- and bioinformatics for knowledge mapping to create and advance in vivo -ready therapeutics while simultaneously performing ADME-Tox (absorption, distribution, metabolism, excretion, and toxicity) lead profiling. (genengnews.com)
  • We award the Hertie Prize and various grants to individuals, associations, and initiatives in the field of multiple sclerosis and other nervous system diseases. (ghst.de)
  • For over 30 years, the Hertie Foundation has been recognizing people and groups demonstrating exceptional dedication and creativity in the areas of multiple sclerosis and neurodegenerative diseases (e.g. (ghst.de)
  • Acrolein has been demonstrated to be involved in many central nervous system diseases, such as neurotrauma, Multiple Sclerosis, Alzheimer's disease, Parkinson's disease, etc. (purdue.edu)
  • In many papers, the pathological effects of neurodegenerative diseases are a result of altered activity in multiple pathways. (hindawi.com)
  • Others are finding ways to improve the quality of life for patients with serious diseases such as multiple sclerosis and diabetes. (medlineplus.gov)
  • Dialogue with tribal members and leaders helped shape the program, and unlike previous programs that funded a small number of tribes to work on specific diseases, this program funds multiple tribal entities to reach widely into Indian Country. (cdc.gov)
  • This project is focused on the development and validation of using positron emission tomography (PET) radiopharmaceuticals to quantify receptors, enzymes, and transporters in the nervous system," Mai said, "with an aim to develop biomarkers with radioactive chains to diagnose neurodegenerative diseases. (owu.edu)
  • The study may also provide further evidence for the involvement of sigma-1 receptors in potentially disease-modifying therapies for Parkinson's disease. (anavex.com)
  • A yes vote on this measure would authorize the state to purchase these bonds, increasing funding for stem cell research on treatments for cancer, Alzheimer's and dozens of other diseases. (capradio.org)
  • Anavex Life Sciences Corp is working to develop novel small molecule treatments for some of the most challenging central nervous system (CNS) diseases facing society today, including Alzheimer's, Parkinson's, Rett syndrome, and other rare diseases. (fragilex.org)
  • Companies that receive funding from MJFF have scientifically compelling plans that hold obvious potential to impact our understanding of Parkinson's and ultimately the development of improved treatments for people with the disease. (anavex.com)
  • The research team explained that such diseases develop in a multistep process whereby proteins misfold and accumulate into large plaques. (nutraingredients.com)
  • In Alzheimer's disease proteins clump together to long fibrils causing the death of nerve cells. (tum.de)
  • If the precise mechanisms by which these heat shock proteins hook up to their disease-causing counterparts were known, scientists could deploy this knowledge to develop agents utilizing these mechanisms to fight disease. (tum.de)
  • The absence of a positive correlation between the geographic distribution of Lyme disease and the distribution of deaths due to Alzheimer disease, ALS, MS, and Parkinson disease provides further evidence that Lyme disease is not associated with the development of these neurodegenerative conditions. (cdc.gov)
  • Lyme disease cases are most commonly reported from the Northeast, mid-Atlantic, and upper Midwest regions of the United States ( 3 ). (cdc.gov)
  • Parkinson disease commonly begins between the ages of 50 and 79. (msdmanuals.com)
  • That is a prejudice that they MUST overcome because we're not in a position to always look our very best or to feel our very best, or to be pleasing to the eye because we have suffered terrible debilitating diseases and injuries. (chrisreevehomepage.com)
  • Addiction is a disorder of the brain's reward system which arises through transcriptional and epigenetic mechanisms and occurs over time from chronically high levels of exposure to an addictive stimulus (e.g., morphine, cocaine, sexual intercourse, gambling, etc. (wikipedia.org)
  • ADHD is an organic disorder of the nervous system. (wikipedia.org)
  • Parkinson's disease is a chronic and progressive neurological disorder that is characterized by well-known motor symptoms including tremors, stiffness of limbs, slowness of movements, and difficulties with posture and balance, as well as by non-motor symptoms. (anavex.com)
  • It is the second most common neurological disorder and approximately one million people in the United States, and from four to six million people worldwide, live with this disease. (anavex.com)
  • For example, if you step on something sharp, the nerves in your foot send a message from neuron to neuron to your central nervous system that says, Hey, this hurts . (webmd.com)
  • U.S. National Library of Medicine: "Nerves," "Nervous System. (webmd.com)
  • We offer women's health services to meet your specific needs such as disease screenings, mental health treatment, recovery from military sexual trauma, maternity care and female-specific medical equipment. (va.gov)
  • Is it possible that IPT might be able to reverse the protein conformation changes of prion diseases such as bovine spongiform encephalopathy and Creutzfeldt-Jakob disease? (iptq.com)
  • Now research has suggested the compound may reduce the abundance small amyloid protein aggregates that are considered to be toxic and cause neuronal dysfunction and memory impairment in Alzheimer's disease. (nutraingredients.com)
  • The mutation results in the production of a disease-causing huntingtin protein. (eurekalert.org)
  • In monkeys, dose-dependent reductions in HTT mRNA and Htt protein throughout the central nervous system were observed after intrathecal administration of an antisense drug. (eurekalert.org)
  • Reports of confirmed Lyme disease cases submitted to the National Notifiable Diseases Surveillance System during 2001-2010 ( 2 ) were used to calculate state-specific, age-adjusted incidence rates of Lyme disease. (cdc.gov)
  • Preventing Chronic Disease [serial online] 2004 Jan [ date need to redesign the current surveillance system to cap- cited ]. (cdc.gov)
  • One of the promising features of IPT is its reported effectiveness in treatment of numerous nervous system diseases. (iptq.com)
  • Senses of smell and taste returned, vertigo and tinnitus eliminated, and hearing and sight improved, by treatment of circulatory and other systems. (iptq.com)
  • Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. (tum.de)
  • Owing to the financial, societal, and personal impact of these diseases, etiologies, prevention, and treatment have become the major focus of basic and clinical research. (hindawi.com)
  • It is very exciting to have the possibility of a treatment that could alter the course of this devastating disease," said clinical study principal investigator Blair R. Leavitt, MD, of the University of British Columbia in Vancouver. (eurekalert.org)
  • Anavex Life Sciences Corp. ("Anavex" or the "Company") (OTCQX: AVXL), a clinical-stage biopharmaceutical company developing drug candidates to treat Alzheimer's disease, other central nervous system (CNS) diseases, pain, and various types of cancer, today announced that it has been awarded a research grant from The Michael J. Fox Foundation for Parkinson's Research (MJFF) to develop ANAVEX 2-73 for the treatment of Parkinson's disease. (anavex.com)
  • 1998. Zinc acetate treatment in Wilson's disease. (cdc.gov)
  • by contributing institutions or for the use of any information through the EurekAlert system. (eurekalert.org)
  • Bactevo is using TIME internally to develop its lead programs in mitochondrial disease. (genengnews.com)
  • To advance this work, the company also is collaborating with researchers at the Wellcome Trust Centre for Mitochondrial Research, a leading center for basic mitochondrial disease research and patient care. (genengnews.com)
  • But the problem is that mice, like many other organisms, do not die from general old age, but from very specific diseases," says Ehninger. (dzne.de)
  • NECTAR - the network for European CNS transplantation and restoration was founded over 25 years ago with the aim of bringing together European groups who share the common goal of protecting, repairing, and restoring the central nervous system from damage caused by degenerative disease or injury. (lu.se)
  • Characteristics of patients misdiagnosed with Alzheimer's disease and their medication use: an analysis of the NACC-UDS database. (roche.com)
  • The MJFF grant is expected to fully fund a preclinical study on the effect of ANAVEX 2-73 in a Parkinson's disease animal model, which seeks to provide a solid dataset that will justify moving forward to clinical development in Parkinson's. (anavex.com)
  • If successful, this study will accelerate the translation of preclinical findings into the very first clinical trial of ANAVEX 2-73 as a potential disease-modifying therapy for Parkinson's disease," said Angela Cenci, MD, PhD, and Professor at Lund University, where the study will be conducted. (anavex.com)
  • It is currently undergoing a Phase 2a clinical trial for Alzheimer's disease. (anavex.com)
  • These include occurrence, frequency, incidence, cause, effect and prog- indices of frequency and severity of disease, disparities or nosis of Alzheimer's disease' and maintain this informa- inequities, costs, preventability, potential clinical course in tion for research purposes (2). (cdc.gov)
  • Associations between Lyme disease and certain neurodegenerative diseases have been proposed, but supportive evidence for an association is lacking. (cdc.gov)
  • however, an inverse correlation was detected between Lyme disease and Alzheimer disease. (cdc.gov)
  • Lyme disease is a complex, multisystem tickborne illness caused by the spirochete Borrelia burgdorferi ( 1 ). (cdc.gov)
  • Researchers have critically evaluated these proposed biologic associations between Lyme disease and Alzheimer disease, ALS, MS, and Parkinson disease, but none have found evidence of an association ( 12 - 21 ). (cdc.gov)
  • We compared Lyme disease incidence rates in each state with death rates for Alzheimer disease, ALS, MS, and Parkinson disease. (cdc.gov)
  • VA Mountain Home Healthcare System offers a wide range of health, support, and facility services for Veterans in a 41-county area of northeastern Tennessee, western Virginia, and southern Kentucky. (va.gov)