• Four analgesic drugs (morphine, levorphan, alphaprodine, dihydrocodeine) and 2 analgesic-antagonists (nalorphine, levallorphan) were studied for their effects on intestinal motility in vitro and in vivo . (aspetjournals.org)
  • 3) Dihydrocodeine and alphaprodine exhibited approximately [unknown] the intestinal spasmogenic potency of morphine. (aspetjournals.org)
  • Betaprodine is some five times more potent than alphaprodine, but is metabolized more rapidly, and only alphaprodine was developed for medicinal use. (wikipedia.org)
  • [1] Betaprodine is some 5x more potent than alphaprodine, [2] but is metabolised more rapidly, and only alphaprodine was developed for medicinal use. (chemeurope.com)
  • Alphaprodine was sold under several brand names, mainly Nisentil and Prisilidine. (wikipedia.org)
  • 21 CFR, 1308.11 (betaprodine) and 1308.12 (alphaprodine). (drugfuture.com)
  • There are two isomers of the trans form of prodine, alphaprodine and betaprodine. (wikipedia.org)
  • Both exhibit optical isomerism and alphaprodine and betaprodine are racemates. (wikipedia.org)
  • Betaprodine produces more euphoria and side effects than alphaprodine at all dose levels, and it was found that 5 to 10 mg of betaprodine is equivalent to 25 to 40 mg of alphaprodine. (wikipedia.org)
  • There are two isomers of prodine, Alphaprodine and Betaprodine. (chemeurope.com)
  • Beckett AH, Walker J. The configuration of alphaprodine and betaprodine. (chemeurope.com)
  • other somewhat more distant relatives include alphaprodine and piritramide. (metakraft.de)
  • Also, the drug is a distant relative of alphaprodine and piritramide. (rehabnear.me)
  • Fung DL, Asling JH, Eisele JH, Martucci R. A comparison of alphaprodine and meperidine pharmacokinetics. (chemeurope.com)
  • Tests in rats showed alphaprodine to be 97% the strength of morphine via the subcutaneous route and 140% the strength of methadone orally. (wikipedia.org)
  • Alphaprodine has a duration of action of 1 to 2 hours and 40 to 60 mg is equal to 10 mg of morphine via the subcutaneous route. (wikipedia.org)