• The different imp alpha proteins exhibit substantial sequence divergence and do not appear to be simply redundant in function. (nih.gov)
  • Disruption of the IMA10 gene encoding an imp alpha-like protein that accumulates in dividing micronuclei results in nuclear division defects and lethality. (nih.gov)
  • Additionally, it reveals that karyopherins could be good candidates as potential DGF predictive clinical biomarkers and targets for pharmacological interventions in renal transplantation. (biomedcentral.com)