Alpha-adrenergic agonists are a class of sympathomimetic agents that selectively stimulates alpha adrenergic receptors. (wikipedia.org)
Alpha 2 receptors are associated with sympatholytic properties. (wikipedia.org)
Nonspecific agonists act as agonists at both alpha-1 and alpha-2 receptors. (wikipedia.org)
ergotamine etilefrine indanidine mephentermine metaraminol methoxamine mivazerol naphazoline norfenefrine octopamine phenylpropanolamine propylhexedrine rilmenidine romifidine synephrine talipexole Alpha-adrenergic agonists, more specifically the auto receptors of alpha 2 neurons, are used in the treatment of glaucoma by decreasing the production of aqueous fluid by the ciliary bodies of the eye and also by increasing uveoscleral outflow. (wikipedia.org)
It binds to alpha-adrenergic receptors in the nasal mucosa. (drugbank.com)
The four main receptors are alpha 1 , alpha 2 , beta 1 , and beta 2 , which mediate the major responses described in Table 15.1 and illustrated in Fig. 15.1 . (basicmedicalkey.com)
FIG. 15.1 Effects of activation of alpha 1 , alpha 2 , beta 1 , and beta 2 receptors. (basicmedicalkey.com)
It achieves this by promoting the action of alpha adrenergic receptors present in these areas. (lybrate.com)
Both drugs are direct agonists on effector cells, and their actions differ mainly in the ratio of their effectiveness in stimulating alpha and beta2-receptors. (web.app)
These medications act on the alpha-adrenergic receptors in the arterioles of the nasal mucosa. (pipelinepharma.com)
It is a sympathomimetic catecholamine that works with both alpha and beta-adrenergic receptors. (aclsonline.us)
Smaller doses primarily work on beta receptors, while larger doses are more selective for alpha receptors. (aclsonline.us)
1 Efferent sympathetic signals regulate BP, heart rate and cardiac output through beta (β)-adrenergic receptors, and regulate peripheral resistance by vasoconstriction through alpha (α)-adrenergic receptors. (icrjournal.com)
In the kidney, sodium and water retention is stimulated by activation of β-adrenergic receptors in the proximal tubules. (icrjournal.com)
In addition to causing vasoconstriction, experimental data from animal studies show that sumatriptan also activates 5-HT 1 receptors on peripheral terminals of the trigeminal nerve innervating cranial blood vessels. (nih.gov)
Epinephrine4
Alpha adrenoreceptor ligands mimic the action of epinephrine and norepinephrine signaling in the heart, smooth muscle and central nervous system, with norepinephrine being the highest affinity. (wikipedia.org)
The drop induces systemic vasoconstriction to reduce blood flow in the nasal passage and conjunctiva. (lybrate.com)
This activates the adrenal system to result in systemic vasoconstriction which subsequently decreases the blood flow in the nasal passage. (pipelinepharma.com)
It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. (uams.edu)
When stimulated, alpha adrenergic receptor sites in the arteries will constrict arteries making their lumens narrower. (truman.edu)
The vascular 5-HT 1 receptor subtype that sumatriptan activates is present on cranial arteries in both dog and primate, on the human basilar artery, and in the vasculature of human dura mater and mediates vasoconstriction. (nih.gov)
Agonists and antagonists1
Intravenous (IV) adrenergic agonists and antagonists are high-alert medications because they can cause significant harm to a patient in the event of a medication error. (basicmedicalkey.com)
Peripheral1
Antihypertensive medications that either reduce the levels of plasma testosterone (male sex hormone), increase estrogen (female sex hormone), or cause peripheral vasoconstriction can cause erectile dysfunction. (dibesity.com)
However, now comes my confusion, by causing vasoconstriction, yes, we increase pressure, but we decrease blood flow, so how does it increase venous return and also the stroke volume? (stackexchange.com)
Arterial vasoconstriction makes increased venous return make sense, the tube is tighter so more gets through to the other end. (stackexchange.com)
Distribution of adrenergic receptor subtypes and adrenergic receptor number are important factors in organ or cellular responses to adrenergic input. (pharmacology2000.com)
Blockade2
There was resolution of symptoms, absence of new infarctions, and improvement in vessel caliber after adequate alpha-adrenergic receptor blockade for the management of pheochromocytoma. (stanfordhealthcare.org)
Alpha-adrenergic receptor blockade can reverse cerebral vasoconstriction and prevent further cerebral ischemia and infarctions. (stanfordhealthcare.org)
Drugs2
This chapter discusses two groups of drugs that affect the sympathetic nervous system-adrenergic agonists, or sympathomimetics , and adrenergic antagonists, also called adrenergic blockers or sympatholytics -along with their dosages and uses. (basicmedicalkey.com)
Drugs with beta 2 -adrenergic properties include isoproterenol and dobutamine. (truman.edu)
Hypotension1
The reduction of the stress response caused by alpha 2 agonists were theorised to be beneficial peri operatively by reducing cardiac complications, however this has shown not to be clinically effective as there was no reduction in cardiac events or mortality but there was an increased incidence of hypotension and bradycardia. (wikipedia.org)
4. After administration of adrenaline, it shows a powerful vasoconstriction action with the help of alpha- adrenergic stimulation. (nursingpaperexperts.com)
Isoproterenol1
Isoproterenol with limited activity at alpha recetors has little effect. (pharmacology2000.com)
Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), d-alpha-Tocopherol is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. (medindex.am)
Effector cells1
They act on one or more adrenergic receptor sites located in the effector cells of muscles such as the heart, bronchiole walls, gastrointestinal (GI) tract, urinary bladder, and ciliary muscles of the eye. (basicmedicalkey.com)
Vivo1
Verapamil/nitroglycerin was effective for at least 2 h in vitro, but did not prevent vasoconstriction after 2 h in vivo. (ox.ac.uk)
Prevent1
To prevent sloughing and necrosis in areas in which extravasation has taken place, the area should be infiltrated as soon as possible with 10 mL to 15 mL of saline solution containing from 5 mg to 10 mg of an adrenergic blocking agent. (nih.gov)