• We tried multiple times previously to create monoclonal and polyclonal antibodies to claudin-2 and MLCK1. (bicellscientific.com)
  • The polyclonal antibody you generated for KIAA0408 is stunning! (bicellscientific.com)
  • Catenin, beta [Polyclonal] Antibody (cGMP). (enquirebio.com)
  • imgenex, 770 antibody to dnmt3b ( clone 52a1018 1:200 ) 771 bcl 6 anti body conc 772 cdk 4 anti body conc 773 gata2 antibody conc 774 mdm2 antibody conc 775 pck1 conc 776 sf 1 conc 777 bob 1 conc 778 pit 1 conc 779 antigap43 antibody 780 anti eber associated protein antibody, polyclonal 781 brilliant cresyl blue 782 phospho. (tendersindelhi.com)
  • Polyclonal Antibody Branched chain a-keto acid dehydrogenase kinase (BCKD)ab. (clonagen.com)
  • The following product was used in this experiment: PPAR gamma-2 Polyclonal Antibody from Thermo Fisher Scientific, catalog # PA1-824, RRID AB_2166200. (thermofisher.com)
  • The following product was used in this experiment: Dystroglycan Polyclonal Antibody from Thermo Fisher Scientific, catalog # 11017-1-AP. (thermofisher.com)
  • Rabbit polyclonal antibodies (pAb) were used for preparing a gold-pAb conjugate, and the rGroEL-specific mouse monoclonal antibody was used as the antigen detection reagent at the ICT test line. (jsce-ip.com)
  • Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. (abcam.com)
  • Actin binding domains present in duplicate at the N-termini of spectrin-like proteins (including dystrophin, alpha-actinin). (embl.de)
  • Dystrophin is an important cytoskeletal protein which belongs to the β-Spectrin/α-actinin. (iit.edu)
  • These include spectrin alpha and beta subunits [ ( PUBMED:12672815 ) ( PUBMED:15062087 ) ], alpha-actinin [ ( PUBMED:10481917 ) ] and dystrophin. (embl.de)
  • The same repeats are also present in alpha-actinin, dystrophin and utrophin. (embl.de)
  • The α-actinins are 100 kD rod shaped proteins that form head-to-tail homodimers [ 18 ]. (biomedcentral.com)
  • There are four human α-actinin (ACTN1-4) family members, encoding closely related actin crosslinking proteins. (biomedcentral.com)
  • A number of actin-binding proteins, including spectrin, alpha-actinin and fimbrin, contain a 250 amino acid stretch called the actin binding domain (ABD). (embl.de)
  • Click on each link to view available results for O60934 antibodies, publications, images and proteins matching your search term. (antibodyreview.com)
  • Sequence alignments and phylogenetic trees of these domains allow us to interpret the evolutionary relationship between these proteins, concluding that spectrin evolved from alpha-actinin by an elongation process that included two duplications of a block of seven repeats. (embl.de)
  • The low fre- and EPEC, the proteins that mediate this attachment are quency of antibodies to Stx1 (in 12% of Mexican and in encoded in a chromosomal pathogenicity island called the 22% of U.S. samples) suggests that the rare appearance of "locus of enterocyte effacement" (LEE) (3). (cdc.gov)
  • Application: Serological studies of influenza A virus, immunogen for antibody production. (researchd.com)
  • anti nf kb p65 antibody 783 anti stat6 antibody 784 anti cd 19 antibody 785 anti cd 38 antibody 786 anti pten ab 787 anti ck9 antibody 788 anti gh antibody 789 anti lh beta antibody 790 anti tsh alpha antibody 791 anti fsh alpha antibody 792 anti hpv antibody 793 anti ebv nuclear antigen ab 794 anti ebv latent memb. (tendersindelhi.com)
  • This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. (thermofisher.com)
  • Mouse monoclonal antibody raised against full length native of rabbit troponin T. (abnova.com)
  • Recombinant goat monoclonal antibody raised against rabbit IgG Fab. (abnova.com)
  • Recombinant goat monoclonal antibody raised against rabbit IgG Fc. (abnova.com)
  • Serology performed in samples of both toxicity studies showed significant and substantial anti-VLP-specific antibody titers for rNV-2v vaccines administered via the IM or SC route www.joplink.net/rabbit-antibodies , as well as relevant NoV blocking antibody responses. (jsce-ip.com)
  • The presence of C. burnetii DNA in swabs and the tick H. lusitanicum was determined by PCR and serum antibodies by ELISA. (jsce-ip.com)
  • Alderete, working with co-author Hermes Chan from the company MedMira, used the diagnostic platform of the company for his finger-prick test to detect for antibody to the target protein. (worldhealth.net)
  • I am strongly inclined to generate monoclonal antibody for this protein too and we should think about patenting it. (bicellscientific.com)
  • protein 795 anti cd 163 796 anti gap43 antibody 797 anti lin28 antibody ( preferably thermoscientific ) 798 xl iso ( 17q ) 799 brilliant cresyl blue 800 fecal occult blood test ( fobt ) , kit 801 phospho. (tendersindelhi.com)
  • By Western blot, this antibody detects an ~56 kDa protein representing PPAR gamma 2 from NIH-3T3 cell lysate. (thermofisher.com)
  • The yeast surface display technique was used to effectively screen and select the yeast scFv clones containing the monospecific antibody against our target spliced variant D14 (15"16") 17 protein and D2:3. (iit.edu)
  • In vitro binding assays have suggested that talin and -actinin may associate directly with 1 integrin (Horwitz et al. (ppbhg.org)
  • U.S. are exposed to attaching/effacing enteropathogens merized actin, -actinin, talin, and ezrin (2). (cdc.gov)
  • PPAR alpha is expressed mainly in skeletal muscle, heart, liver, and kidney and is thought to regulate many genes involved in the beta-oxidation of fatty acids. (thermofisher.com)
  • Mutations in the Alpha-actinin-4 gene (ACTN4) cause a rare form of familial focal segmental glomerulosclerosis in humans. (biomedcentral.com)
  • α-Actinin monomers contain three distinct domains: an N-terminal actin binding domain (ABD), four spectrin-like repeats (SRs), and a C-terminal EF hands (calmodulin like domain). (biomedcentral.com)
  • Alpha-actinin and spectrin structures: an unfolding family story. (embl.de)
  • The newly described crystallographic structures of two consecutive homologous repeats of human alpha-actinin, a member of the spectrin superfamily, shed new light on alpha-actinin interchain binding properties. (embl.de)
  • Here I present evidence that interchain binding at the tail end of the spectrin molecule is likely to occur via a mechanism similar to that observed for alpha-actinin. (embl.de)
  • Alpha-actinin and spectrin have common structural domains. (embl.de)
  • The alpha- and beta-subunits of spectrin are made of repeated homologous units of 106 residues. (embl.de)
  • In the recently reported partial sequence of the chicken non-muscle alpha-actinin, a repetitive sequence homologous to the internal repeat in spectrin occurs several times. (embl.de)
  • Both spectrin and alpha-actinin are components of the cytoskeletal network, the integrity of which is based on multiple and complex interactions. (embl.de)
  • We suggest that the shared domain structure indicates common structural principles or interactions of spectrin and alpha-actinin and reflects their common evolution. (embl.de)
  • In either pre-nephritic NZB/W F1 or BALB/c mice the shot of anti-dsDNA antibodies would bring about immediate (cross-reactive) or indirect (chromatin-mediated) binding to mesangial cells [8 9 10 Prior studies also have confirmed that anti-dsDNA isolated from LN sufferers could bind to individual mesangial cells and its own binding activity correlated with disease activity [11]. (gasyblog.com)
  • A range of anti-dsDNA binding goals on mesangial cells continues to be proposed plus they consist of annexin II α-actinin laminin or heparin sulphate [9 12 13 14 Within this framework the binding activity of anti-dsDNA to annexin II carefully links with disease activity in individual LN and glomerular annexin II appearance co-localizes with IgG and C3 debris and correlates with intensity of nephritis [9]. (gasyblog.com)
  • Anti-α-actinin antibodies produced by Epstein-Barr pathogen change of lymphocytes isolated from SLE sufferers would cross-react with α-actinin and these cross-reacting antibodies could bind to mesangial cells and isolated glomeruli [13]. (gasyblog.com)
  • Furthermore alpha-actinin 4 and a splice variant of α-actinin 1 are both extremely portrayed in mesangial cells isolated from MRL/lpr mice and these observations recommended that upregulated α-actinin appearance may influence the level of immunoglobulin deposition in the pathogenesis of LN [14]. (gasyblog.com)
  • Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial is an enzyme that in humans is encoded by the SUCLG1 gene. (wikipedia.org)
  • This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. (wikipedia.org)
  • In the dephosphorylated structure, a phosphate ion works in coordination with a histidine residue in the active site and the two alpha helices, one contributed by each subunit of the alphabeta-dimer to stabilize the structure. (wikipedia.org)
  • Your ARL13B antibody works beautifully! (bicellscientific.com)
  • 7. F, G IMCD3 cells were starved for 24 h to induce ciliation and immunostained for (F) Filamin A and Arl13b or Obeticholic Acid (G) alpha\actinin and acetylated tubulin. (crispr-reagents.com)
  • We could further confirm this in human hTERT\RPE1 cells, an immortalized cell line derived from human retinal pigmental epithelial cells which has been widely used for cilia research (Fig EV1A), and STED microscopy showed alpha\actinin as two distinct puncta at the ciliary base (Fig EV1B). (crispr-reagents.com)
  • Anti-BCL-2 antibodies were in the IgG type as well as titers varied coming from 1:1,Thousand for you to 1:A hundred,000 with maximum titers ahead of remedy and minimizing little by little in the course of remission. (assayway.com)
  • Similar to COVID‑19 and pregnancy tests, the results are displayed in a window with a dot appearing if the antibody is present, indicating infection. (worldhealth.net)
  • Anti-GFAP antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. (bicellscientific.com)
  • In the nervous system, synemin was found to associate with ruffled membranes of reactive astrocytes and to also co-localize with α-actinin, suggesting a role in cell motility [ 15 ]. (biomedcentral.com)
  • As detailed in this study, the new test requires only a drop of blood to detect an antibody specific to trich. (worldhealth.net)
  • This antibody does not detect PPAR alpha or PPAR delta. (thermofisher.com)
  • Nucleosomes may also be important intra-renal goals of autoantibodies and the increased loss of intra-renal nuclease would promote nucleosome deposition and therefore the advancement and binding of autoantibodies [15 16 The current presence of circulating chromatin fragments is certainly very important to glomerular mesangial matrix deposition of anti-dsDNA antibody-containing immune system complexes in murine LN [10]. (gasyblog.com)
  • The lesions are char- orrhagic Escherichia coli (EHEC) in milk of 123 women acterized by localized destruction of brush border from the United States and Mexico to determine whether regional differences existed in the frequency of antibodies microvilli and intimate adhesion of the bacterium to the to these surface antigens. (cdc.gov)
  • One of the alpha helices contains amino acids, the modification of which result in conformational changes that accommodate either the bound phosphoryl group or the free phosphate ion. (wikipedia.org)
  • It comprises of an amino terminal domain, alpha helical coiled structure COOH domain, central rod region with 24 STRs and four proline rich hinge regions. (iit.edu)
  • Cultured chicken embryonic cardiomyocyte transfected with GFP control vector in the nucleus, stained with alpha-actinin at the Z-lines in red and Tropomodulin1 (at the pointed ends of the actin filame. (ucsd.edu)
  • FFPE-specific recognition antibodies are made against the same epitope sequence with novel cross-linking and stabilizing technique to lock the conformational state of epitope in a folded state similar to aldehyde induced fixation. (bicellscientific.com)
  • Western blot-specific recognition antibodies are made against the same epitope sequence with novel denaturing and stabilizing technique to prevent the natural folding of epitope in order to lock its conformation in unfolded state. (bicellscientific.com)
  • our data imply that, in the kidney, loss of tensin leads to alpha-Boswellic acid a weakening, rather than a severing, of focal adhesion. (ppbhg.org)
  • Most interestingly, in the more mildly affected regions, immunogold labeling with antibodies against p130cas displayed both large (not shown) and small (shown) clusters alpha-Boswellic acid of gold particles at the base of the basal lateral labyrinth (Fig. (ppbhg.org)
  • Cultured chicken embryonic cardiomyocyte fixed and stained for alpha-actinin using a monoclonal antibody and Alexa-546 as a secondary fluorescent antibody. (cellimagelibrary.org)
  • The alpha and beta subunits are homologous with approximately 30% identity. (embl.de)
  • PPAR gamma 2, like several other nuclear hormone receptors, heterodimerizes with retinoic X receptor (RXR) alpha to form a transcriptionally competent complex. (thermofisher.com)
  • A common nonsense mutation results in alpha-actinin-3 deficiency in the general population. (krisallys.com)
  • Mouse monoclonal antibody raised against native myosin. (abnova.com)
  • Mouse monoclonal antibody raised against macrophage/monocyte. (abnova.com)
  • Elevated anti-α-actinin antibodies titres are discovered ahead of or at disease starting point in LN sufferers in comparison to energetic or inactive lupus sufferers who didn't have proof nephritis [12]. (gasyblog.com)
  • Although these studies warrant independent confirmation, they support the notion that apoptotic cells could harbor the immunogens responsible for antinuclear antibody formation. (biomedcentral.com)
  • Confocal (left panel) and STED (right panel) imaging of RPE1 cells stained with antibodies directed against alpha\actinin and acetylated tubulin. (crispr-reagents.com)
  • As a result of this work we are pleased to now offer this antibody in purified format. (abcam.com)