• Alpha-adrenergic agonists are a class of sympathomimetic agents that selectively stimulates alpha adrenergic receptors. (wikipedia.org)
  • Alpha 2 receptors are associated with sympatholytic properties. (wikipedia.org)
  • Nonspecific agonists act as agonists at both alpha-1 and alpha-2 receptors. (wikipedia.org)
  • ergotamine etilefrine indanidine mephentermine metaraminol methoxamine mivazerol naphazoline norfenefrine octopamine phenylpropanolamine propylhexedrine rilmenidine romifidine synephrine talipexole Alpha-adrenergic agonists, more specifically the auto receptors of alpha 2 neurons, are used in the treatment of glaucoma by decreasing the production of aqueous fluid by the ciliary bodies of the eye and also by increasing uveoscleral outflow. (wikipedia.org)
  • Naloxone is a potent antagonist at the mu opioid receptors and produces opioid withdrawal signs and symptoms in individuals physically dependent on full opioid agonists when administered parenterally. (medscape.com)
  • Compounds that bind to and activate ADRENERGIC ALPHA-2 RECEPTORS. (rush.edu)
  • beta-Adrenergic receptors showed little or no change in any region. (duke.edu)
  • Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (ebi.ac.uk)
  • An agent that selectively binds to and activates alpha -adrenergic receptors. (ebi.ac.uk)
  • What are the 4 basic categories of adrenergic receptors? (brainscape.com)
  • What type of receptor are adrenergic receptors? (brainscape.com)
  • What are the 4 main factors that can alter the degree to which an adrenergic receptors respond to a stimulus? (brainscape.com)
  • When the active metabolites of kratom bind to these receptors, they cause vasoconstriction, papillary constriction, and constriction of smooth muscles in the genitourinary tract. (kratom.org)
  • Thus, because kratom and tamsulosin have opposite effects mediated by the alpha-adrenergic receptors, they will become ineffective if combined. (kratom.org)
  • The drug mainly acts on alpha-1 adrenergic receptors. (kratom.org)
  • Kratom and tamsulosin act via alpha-adrenergic receptors. (kratom.org)
  • The drug acts by blocking alpha-1 adrenergic receptors in the genitourinary tract's and relaxing the muscles, especially the bladder's detrusor muscles and prostatic muscles, allowing easy passage of urine through the urethra. (kratom.org)
  • Clenbuterol specifically targets the B2 adrenergic receptor while ephedrine non-selectively targets the alpha and beta adrenergic receptors. (tineb.org)
  • Agonist-induced changes in the properties of beta-adrenergic receptors on intact S49 lymphoma cells. (aspetjournals.org)
  • Osei-Owusu P, Scrogin KE: Buspirone raises blood pressure through activation of sympathetic nervous system and by direct activation of alpha1-adrenergic receptors after severe hemorrhage. (arlen.com.br)
  • It binds to alpha-adrenergic receptors in the nasal mucosa. (drugbank.com)
  • [1] Recently for opioid and alpha 2 -adrenergic receptors, a peripheral analgesia was demonstrated. (asahq.org)
  • This is a first-generation antihistamine with anticholinergic effects that binds to H1 receptors in the CNS and the body. (medscape.com)
  • It competitively blocks histamine from binding to H1 receptors. (medscape.com)
  • 2 Agonism of beta-1 and beta-2 adrenergic receptors causes the alpha subunit of G-protein coupled receptors to exchange GMP for GTP, activating them, and allowing the alpha subunit to dissociate from the beta and gamma subunits. (drugbank.com)
  • Agonism of beta-1 adrenergic receptors lead to increased strength of contractility, conduction of nerve impulses, speed of relaxation, and rate in the heart. (drugbank.com)
  • Agonism of beta-2 adrenergic receptors leads to glycogenolysis in the liver, 5 glucagon release from the pancreas, and activation of the renin-angiotensin-aldosterone system. (drugbank.com)
  • In the alveoli, agonism of beta-2 adrenergic receptors, activates similar pathways to the heart, however the end result is regulation of sodium channels, the cystic fibrosis transmembrane conductance regulator (CFTR), and sodium potassium ATPase. (drugbank.com)
  • 10 Agonism of beta-2 adrenergic receptors can also increase chloride ion transport across CFTR. (drugbank.com)
  • Regulatory proteins that down-regulate phosphorylated G-protein membrane receptors, including rod and cone photoreceptors and adrenergic receptors. (lookformedical.com)
  • A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). (lookformedical.com)
  • The adrenergic beta-2 receptors are more sensitive to EPINEPHRINE than to NOREPINEPHRINE and have a high affinity for the agonist TERBUTALINE. (lookformedical.com)
  • A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS and a variety of other G-PROTEIN-COUPLED RECEPTORS. (lookformedical.com)
  • A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. (lookformedical.com)
  • Accordingly, Prazosin is a selective inhibitor of the alpha1 subtype of alpha adrenergic receptors. (pharmacycode.com)
  • There are many adrenergic receptors. (basicmedicalkey.com)
  • The four main receptors are alpha 1 , alpha 2 , beta 1 , and beta 2 , which mediate the major responses described in Table 15.1 and illustrated in Fig. 15.1 . (basicmedicalkey.com)
  • The alpha-adrenergic receptors are located in the blood vessels, eyes, bladder, and prostate. (basicmedicalkey.com)
  • The alpha 2 receptors are located in the postganglionic sympathetic nerve endings. (basicmedicalkey.com)
  • The beta 2 receptors are found mostly in the smooth muscles of the lung and GI tract, the liver, and the uterine muscle. (basicmedicalkey.com)
  • Other adrenergic receptors are dopaminergic and are located in the renal, mesenteric, coronary, and cerebral arteries. (basicmedicalkey.com)
  • FIG. 15.1 Effects of activation of alpha 1 , alpha 2 , beta 1 , and beta 2 receptors. (basicmedicalkey.com)
  • These pits are the entry route for macromolecules bound by cell surface receptors. (lookformedical.com)
  • Endosomes internalize macromolecules bound by receptors on the cell surface. (lookformedical.com)
  • Heart failure (HF) is characterized by markedly elevated levels of catecholamines that bind to adrenergic receptors (ARs) in the heart. (unc.edu)
  • Other medications, which are relatively selective for β 2 -adrenergic receptors, retain the benefits in management of asthma and COPD, while limiting adverse effects mediated by β 1 -adrenergic receptor activation. (pharmacology2000.com)
  • At higher doses β 2 -selective adrenergic agonists are still able to activate β 1 -receptors, again emphasizing the role of drug concentration in drug specificity. (pharmacology2000.com)
  • Approaches to targeting β 2 -pulmonary adrenergic receptors involves not only drug design but also drug delivery. (pharmacology2000.com)
  • For example, administration of drug by aerosol targets β 2 pulmonary receptors, while limiting systemic drug. (pharmacology2000.com)
  • These effects are largely mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 and 2 (CB1 and CB2)[A32585,A32824]. (rcsb.org)
  • The primary psychoactive component of Cannabis, delta 9-tetrahydrocannabinol (Δ9-THC), demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors. (rcsb.org)
  • Clenbuterol works by stimulating beta-2 receptors, which are found in the muscles and fatty tissues of the body, precision gear works clenbuterol. (koffemaniya.ru)
  • Selectively blocks beta1-adrenergic receptors with little or no effect on beta2-receptors. (medscape.com)
  • When released into the bloodstream, epinephrine binds to multiple receptors and has numerous effects throughout the body. (the-medical-dictionary.com)
  • Chordin like-1 (CHRDL1) is an antagonist of bone morphogenetic proteins (BMPs) that acts through binding BMPs and blocking their interaction with BMP receptors. (bvsalud.org)
  • It belongs to a class of drugs called beta-2 agonists, which work by stimulating the beta-2 receptors in the body. (alcafricanos.com)
  • Clenbuterol works by binding to the beta-2 receptors in the body, which then stimulates the sympathetic nervous system. (alcafricanos.com)
  • The use of clenbuterol along with T3 can produce an additive lipolytic effect: T3 increases the number of receptors, while clenbuterol binds to the receptors activating HSL and increasing lipolysis. (xoivotv.info)
  • A imidazole derivative that is an agonist of ADRENERGIC ALPHA-2 RECEPTORS. (drugcentral.org)
  • According to the companies' statement, pupillary dilation is controlled primarily by radial iris dilator muscles, which are activated by alpha-1 adrenergic receptors. (healthiscure.com)
  • Phentolamine binds to the receptors on radial iris dilator muscles surrounding the pupil to reduce pupil diameter. (healthiscure.com)
  • It has a role as a bronchodilator agent, a beta-adrenergic agonist and a sympathomimetic agent. (kimiamahvand.ir)
  • Contents hide 1 #1 - Clenbuterol is a very powerful sympathomimetic drug 2 #2 - Clenbuterol will only be effective if you are very lean 3 #3 - Clenbuterol will make you jittery and wired 4 #4 - Start with a very low dose of Clen and increase until you reach a tolerable dose 5 #5 - Be aware of the side effects. (vira-design.ir)
  • Summary(written by Danielle Lovisone) As a sympathomimetic and Beta-2 agonist, clenbuterol have several deleterious effects on the human body. (com.bo)
  • The high potency of Ro 25-1553 extends to studies on isolated, histamine-contracted, human bronchial smooth muscle, where Ro 25-1553 exhibits a 390-fold enhancement over native VIP and is more potent than other bronchodilating drugs, such as the beta 2-adrenoceptor agonists isoproterenol and salbutamol. (aspetjournals.org)
  • There were no significant changes in SERCA2a expression in the isoproterenol group, although 2 of 5 hearts expressed only 50% of the mean control level Studies have found that it can protect neurons from oxidative stress and inflammation, both of which are believed to contribute to the degeneration of dopamine-producing cells in PD, clenbuterol leginfo. (kimiamahvand.ir)
  • Between 2 and 20 wk of age, these mice develop four chamber cardiac dilatation, decreased systolic and diastolic left ventricular function, and attenuated contractile responses to the beta-adrenergic agonist, isoproterenol. (nih.gov)
  • When comparing the non-selective adrenergic agonist isoproterenol to albuterol, at doses that produce comparable bronchodilation, albuterol will exhibit substantially less cardiac stimulation. (pharmacology2000.com)
  • Partial opioid agonist and potent antagonist, is a potent analgesic that can be administered once a day to block withdrawal symptoms. (medscape.com)
  • Buprenorphine is a semisynthetic narcotic mixed agonist-antagonist analgesic. (medscape.com)
  • Tamsulosin is an alpha-1 receptor antagonist [ 2 ]. (kratom.org)
  • Tissue heterogeneity of calcium channel antagonist binding sites labeled by [3H]nitrendipine. (aspetjournals.org)
  • AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 an. (targetmol.com)
  • AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIA. (targetmol.com)
  • In the MIRA-2 and MIRA-3 trials, a total of 553 subjects aged 12 to 80 years, who had mydriasis induced by instillation of phenylephrine or tropicamide or a combination of hydroxyamphetamine hydrobromide and tropicamide (Paremyd) were randomized. (ocuphire.com)
  • In the human prostate, Prazosin antagonizes phenylephrine (alpha1 agonist)-induced contractions, in vitro , and binds with high affinity to the alpha1c adrenoceptor, which is thought to be the predominant functional type in the prostate. (pharmacycode.com)
  • Studies in normal human subjects have shown that Prazosin competitively antagonized the pressor effects of phenylephrine (an alpha1 agonist) and the systolic pressor effect of norepinephrine. (pharmacycode.com)
  • The α1B mediates cardiac hypertrophy induced by non-selective α1-AR agonists like phenylephrine. (unc.edu)
  • Prodrug metabolized to desglymidodrine, a selective alpha1-adrenoreceptor agonist. (medscape.com)
  • Scholars@Duke publication: Fetal terbutaline exposure causes selective postnatal increases in cerebellar alpha-adrenergic receptor binding. (duke.edu)
  • Despite the absence of body or brain growth impairment, selective increases were seen postnatally in cerebellar alpha 1- and alpha 2-receptor subtypes, whereas the same receptor populations were decreased by small amounts in cerebral cortex and midbrain + brainstem. (duke.edu)
  • What is the result of selective binding? (brainscape.com)
  • What is the degree of selective binding dependent on? (brainscape.com)
  • Characterization of the selective inhibition of the delta subclass of opioid binding sites by alcohols. (aspetjournals.org)
  • Isoprenaline is a catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. (drugbank.com)
  • Isoprenaline is a non-selective beta adrenergic receptor agonist used in a number of indications for the heart, as well as bronchospasm in anesthesia. (drugbank.com)
  • Isoprenaline is a non-selective beta adrenergic receptor agonist. (drugbank.com)
  • We recently showed that an oral selective α1A agonist drug, dabuzalgron, preserves ATP content and mitochondrial function in mouse HF models. (unc.edu)
  • Previously, descriptions of pharmacological effects associated with 'non-selective' β-adrenergic receptor agonists used to manage pulmonary diseases such as asthma or COPD necessarily include unwanted side effects often due to β 1 adrenergic receptor activation. (pharmacology2000.com)
  • The premise of β 2 -agonist-mediated receptor activation (applying also to 'non-selective' β-receptor agonists) is based on both smooth muscle relaxation and reduced airway resistance. (pharmacology2000.com)
  • is a commonly used selective β 2 -adrenergic receptor agonist that may be administered either orally or by inhalation. (pharmacology2000.com)
  • Selective FP prostanoid receptor agonist believed to reduce IOP by increasing uveoscleral outflow. (medscape.com)
  • Description Clenbuterol is a substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2- (tert-butylamino)-1-hydroxyethyl group. (kimiamahvand.ir)
  • https://fitunit.net/clenbuterol-fotos-clenbuterol-efecto-mujeres/ Clenbuterol is a chemical called a beta-2-adrenergic agonist. (kimiamahvand.ir)
  • Clenbuterol is a beta2-agonist drug which acts as a bronchodilator and decongestant to assist with breathing in asthmatics and those with other breathing conditions. (kimiamahvand.ir)
  • Clenbuterol is a chemical called a beta-2-adrenergic agonist. (koffemaniya.ru)
  • Clenbuterol is a popular beta-2 agonist drug that is primarily used as a bronchodilator to treat asthma. (alcafricanos.com)
  • Published: 24 May 2022 Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein Joseph R. Ephedrine is a stimulant that activates the sympathetic nervous system. (com.bo)
  • Looking for a reliable source for clenbuterol - Page 2. (com.bo)
  • Clenbuterol is a β 2 agonist with some structural and pharmacological similarities to epinephrine and salbutamol, but its effects are more potent and longer-lasting as a stimulant and thermogenic drug. (com.bo)
  • Clenbuterol is a well-known beta-2 adrenergic receptor agonist that is used in animal research. (com.bo)
  • The activation of α1 stimulates the membrane bound enzyme phospholipase C, and activation of α2 inhibits the enzyme adenylate cyclase. (wikipedia.org)
  • Inhibits beta-adrenergic input. (medscape.com)
  • LCL161, a SMAC mimetic, effectivity binds to and inhibits multiple IAPs (i.e. (targetmol.com)
  • Alpha-adrenergic agonists have the opposite function of alpha blockers. (wikipedia.org)
  • Two uses for opioid analgesics are as follows: (1) Oral substitution therapy or maintenance therapy or opioid agonist therapy (OAT) refers to substitution of an oral opioid for injected heroin, with the goal of reducing harmful behaviors associated with heroin use. (medscape.com)
  • 2) Detoxification, or controlled withdrawal with the goal of abstinence, is based on the principle of cross-tolerance in which one opioid is replaced with another and then slowly withdrawn. (medscape.com)
  • Also a preferred agent for opioid agonist maintenance. (medscape.com)
  • Discrimination of three types of opioid binding sites in rat brain in vivo. (aspetjournals.org)
  • Epinephrine is used as a drug to promote peripheral vascular resistance via alpha-stimulated vasoconstriction in cardiac arrest and other cardiac disrhythmias resulting in diminished or absent cardiac output, such that blood is shunted to the body's core. (the-medical-dictionary.com)
  • When two drugs that require the same CYP enzymes are taken simultaneously, they compete to bind to such enzymes. (kratom.org)
  • Belonging to the azaspirodecanedione drug class, 2 buspirone is a serotonin 5-HT 1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. (arlen.com.br)
  • An in vitro study indicated that buspirone did not displace highly protein-bound drugs such as phenytoin, warfarin, and propranolol from plasma protein, and that buspirone may displace digoxin. (arlen.com.br)
  • Smart Drugs 2. (hedweb.com)
  • Short-acting β 2 -adrenergic agonists administered by inhalation represent drugs of choice for management of acute asthma presentations and for prevention of exercise-induced bronchospastic reactions. (pharmacology2000.com)
  • Time-dependent changes in the affinity of the receptor for agonists. (aspetjournals.org)
  • Alpha blocker Adrenergic agonist Beta-adrenergic agonist Declerck I, Himpens B, Droogmans G, Casteels R (September 1990). (wikipedia.org)
  • A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. (ebi.ac.uk)
  • Side effects of pharmacologically-induced mydriasis include sensitivity to light (photophobia) 2 and blurred vision 2 , which may make it difficult to read, work and drive. (ocuphire.com)
  • With what little I have left of the 2-aminoindan, I might try either a direct halogenation, or electrophilic substitution, to get that halogen onto the 5-position, weather it will have empathogenic, psychedelic or pure stimulant effects, I am not yet sure, but, will have to be tried at some time in the future. (erowid.org)
  • Contributor: Travis Barlock MD Educational Pearls: Alcohol binds the GABA receptor, which produces an inhibitory response, hence the "depressive" effects of ethanol beverages. (emergencymedicalminute.org)
  • Tachycardia and tremor are the most common acute adverse effects of inhaled beta agonists and are dose-related. (msdmanuals.com)
  • The reduction of the stress response caused by alpha 2 agonists were theorised to be beneficial peri operatively by reducing cardiac complications, however this has shown not to be clinically effective as there was no reduction in cardiac events or mortality but there was an increased incidence of hypotension and bradycardia. (wikipedia.org)
  • It is a beta-2 (beta 2) agonist prescribed overseas as a bronchodilator, but not approved for use in this country. (kimiamahvand.ir)
  • It is also used as a bronchodilator for asthma if specific beta-2-adrenergic agonists are unavailable or ineffective. (the-medical-dictionary.com)
  • The regional and subtype selectivity are compatible with primary deficits in the development of noradrenergic projections to the cerebellum identified in previous studies and provide further evidence that therapeutic use of beta-adrenergic agonists may produce neurobehavioral teratology. (duke.edu)
  • The present study focuses on tizanidine, an α 2 noradrenergic (NE) agonist, which is incompletely studied, but is thought to act to depress dorsal horn interneuron excitability [ 14 ]. (biomedcentral.com)
  • In the current study, pregnant rats were given 10 mg/kg of terbutaline on gestational days 17, 18 and 19 and adrenergic receptor binding capabilities examined in brain regions of the offspring. (duke.edu)
  • Dexmedetomidine, an alpha 2 agonist, has been used to manage symptoms of delirium in pediatric patients and is gaining popularity in treatment for pediatric patients with severe anticholinergic toxidrome [ 5 , 6 ]. (hindawi.com)
  • The mechanism of action of xylazine is similar to dexmedetomidine (Precedex), an alpha-2 adrenergic receptor agonist. (emergencymedicalminute.org)
  • Ocuphire Pharma and Viatris Announce FDA Approval of RYZUMVI™ (Phentolamine Ophthalmic Solution) 0.75% Eye Drops for the Treatment of Pharmacologically-Induced Mydriasis Produced by Adrenergic Agonists (e.g. (ocuphire.com)
  • In the U.S., an estimated 100 million comprehensive eye exams take place each year that involve pharmacologically-induced mydriasis (or dilation) of the pupils 1 , which can last up 24 hours 2 . (ocuphire.com)
  • Pharmacologically-induced mydriasis can last up to 24 hours in adults and children 2 . (ocuphire.com)
  • Xylometazoline Oxymetazoline Apraclonidine[citation needed] Cirazoline Epinephrine The following agents are also listed as agonists by MeSH. (wikipedia.org)
  • Empi, Inc., has announced FDA approval of a Lidocaine HCl 2% and Epinephrine 1:100,000 solution for use with the company's Action Patch Iontophoresis System for the iontophoretic induction of local analgesia during superficial dermatologic procedures such as venupuncture, shave removals, and punch biopsies. (the-medical-dictionary.com)
  • Tizanidine is a central alpha-2-adrenergic agonist indicated for the management of spasticity. (nih.gov)
  • Additional therapeutic benefits associated with β-adrenergic receptor agonists likely include reduced pulmonary mast cell leukotriene and histamine release, reduced microvascular permeability, phospholipase A 2 inhibition and increased mucociliary activity. (pharmacology2000.com)
  • Combination of long-acting β-adrenergic receptor agonists with anti-inflammatory agents represents a strongly endorsed therapeutic approach. (pharmacology2000.com)
  • Cough and cold medicines should be used with caution in children younger than 2 years because serious adverse reactions and fatalities have occurred with over-the-counter preparations. (medscape.com)
  • Tamsulosin is an alpha-adrenergic blocker used to treat benign prostatic hyperplasia and ureteric stones. (kratom.org)
  • Prazosin is an alpha-adrenergic blocking agent used to treat hypertension and benign prostatic hyperplasia. (pharmacycode.com)
  • They believe that our cognitive architecture has been so fine-honed by natural selection that any tinkering with such a wonderfully all-adaptive suite of mechanisms is bound to do more harm than good. (hedweb.com)
  • They act on one or more adrenergic receptor sites located in the effector cells of muscles such as the heart, bronchiole walls, gastrointestinal (GI) tract, urinary bladder, and ciliary muscles of the eye. (basicmedicalkey.com)
  • This observation illustrates the relatively weaker albuterol β 1 -receptor activating property compared to its effect at β 2 receptor sites. (pharmacology2000.com)
  • Beta2-adrenergic receptor agonists and beta agonists relax bronchial smooth muscle, decrease mast cell degranulation and histamine release, inhibit microvascular leakage into the airways, and increase mucociliary clearance. (msdmanuals.com)
  • Isoprenaline is 68.8 ± 1.2% protein bound in plasma, mainly to serum albumin. (drugbank.com)
  • Arrestin quenches G-protein activation by binding to phosphorylated photolyzed rhodopsin. (lookformedical.com)
  • Although it is highly homologous to G-PROTEIN-COUPLED RECEPTOR KINASE 2, it is not considered to play an essential role in regulating myocardial contractile response. (lookformedical.com)
  • They have been primarily found as components of ADAPTOR PROTEIN COMPLEX 2. (lookformedical.com)
  • They preferentially bind and release hydrophobic peptides by an ATP-dependent process and are involved in post-translational PROTEIN TRANSLOCATION. (lookformedical.com)
  • SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains(IC50 value of 1.39 nM) and. (targetmol.com)
  • Mechanistic explorations revealed that CHRDL1 is directly bound to insulin-like growth factor binding protein 3 (IGFBP3) and attenuated the degradation of the latter. (bvsalud.org)
  • An overall aim of our research is to study the regulation and function of protein phosphorylation cascades with relevance to type 2 diabetes, with a particular focus on adipose tissue, since this tissue is involved in the pathogenesis of diabetes. (lu.se)
  • The proteins synthesized by parotid acinar cells are stored in large secretory granules whose composition includes α-amylase, leucine-rich parotid secretory protein (PSP), and proline-rich proteins (PRPs), in addition to multiple minor components 2-3 related to digestive and protective functions. (bvsalud.org)
  • α1 agonist: stimulates phospholipase C activity. (wikipedia.org)
  • Cells were transfected with the early B-cell factor-2 (EBF2) to activate progenitor cell differentiation and gauged the tumorigenic potentials of the derived cell subsets. (amegroups.org)