• We investigated the anti-inflammatory potentials of a safe, common dietary flavonoid component, quercetin, for its ability to modulate the production and gene expression of the proinflammatory cytokine tumor necrosis factor alpha (TNF-α) by human peripheral blood mononuclear cells (PBMC). (asm.org)
  • The QUANTUM-1 Study was supported by the National Heart Lung and Blood Institute, the Office of Rare Diseases through the Rare Lung Disease Clinical Research Network (1 U54 RR019498-01, Trapnell PI), and the Alpha-1 Foundation. (copdfoundation.org)
  • Alpha particles quickly lose kinetic energy within a short distance of their source. (enotes.com)
  • In general, external alpha radiation is not harmful since alpha particles are effectively shielded by a few centimeters of air, a piece of paper, or the thin layer of dead skin cells. (enotes.com)
  • If substances emitting alpha particles are ingested, inhaled, injected or introduced through the skin, then it could result in a measurable dose through their ionising effect which eventually changes the polarity of parts of the cells in your body. (enotes.com)
  • But many alpha sources also are accompanied by beta-emitting radio daughters, and alpha emission is also accompanied by gamma photon emission. (enotes.com)
  • What are alpha, beta, and gamma radiation?Explain briefly! (enotes.com)
  • 1. A process for oligomerizing an alpha-olefin which comprises contacting a transition metal halide and an organic halide with an alpha-olefin and thereafter an alkyl aluminum compound in a reaction zone, the mole ratio of the active halogen to aluminum being from 2.5 to 25, and oligomerizing said alpha-olefin to form oligomers having a molecular weight of from about 500 to 5000. (google.com)
  • A. " Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid {alpha}-synuclein fibrils ," by Francesco Simone Ruggeri, Fabrizio Benedetti, Tuomas P. J. Knowles, Hilal A. Lashuel, Sergey Sekatskii, and Giovanni Dietler (Vol. 115 No. 28, July 10, 2018, p. 7230-7235). (wisc.edu)
  • Alpha-1 antitrypsin (AAT) is a protein that protects the lungs. (medlineplus.gov)
  • Alpha fetoprotein (AFP) is a protein produced by the liver and yolk sac of a developing baby during pregnancy. (medlineplus.gov)
  • G protein alpha transducin was purified from bovine retinal extracts more than three decades ago. (springer.com)
  • Only this form is bound by the liver transport protein called alpha-tocopherol transport protein, which carries it to the site where it is incorporated into lipoproteins and carried to other parts of the body. (news-medical.net)
  • The function of alpha tocopherol is as a fat-soluble antioxidant, which breaks the chain of oxidation reactions which are propagating down a cell membrane or plasma protein by means of newly produced free radicals. (news-medical.net)
  • Alpha fetoprotein (AFP) is a protein found in human blood . (everything2.com)
  • Interferon alpha-1/13 is a protein that in humans is encoded by the IFNA1 gene . (rug.nl)
  • Despite considerable evidence linking alpha-synuclein with membranes in vitro, it has proven difficult to demonstrate membrane association of the protein in vivo. (nih.gov)
  • To address the dynamics of the protein in live cells, we have used photobleaching and found that alpha-synuclein exhibits high mobility, although distinctly less than an entirely soluble protein. (nih.gov)
  • The most abundant plasma protein found in the human fetus is alpha-fetoprotein (AFP). (medicinenet.com)
  • It is a genetic defect in the production of a protective protein called alpha-1 antitrypsin, which is made in the liver and circulates in the bloodstream. (scientificamerican.com)
  • 1992) Biochemistry 31, 8619-has been transformed into a functionally homogeneous protein whose properties closely approximate those of normal hemoglobin A. Both of the alpha and beta chains of this hemoglobin contain a valine-methionine substitution at position 1 in order to accommodate the difference in specificity of the protein-processing enzymes of procaryotes. (rcsb.org)
  • Microsoft's Bing is stepping up its assault on Google with bevy of new features available Wednesday that include the addition of Wolfram Alpha search results , enhanced previews of Web sites within results, improved presentation of weather forecasts, and limited Facebook integration. (pcworld.com)
  • As a much-hyped entrant into the knowledge search market, Wolfram Alpha has not escaped comparisons to Google and speculation about whether it could steal some of the search giant's massive market share. (latimes.com)
  • But as rough as it may seem now, Wolfram Alpha looks to be the leading edge of a newer, smarter crop of search engines. (latimes.com)
  • Let's take a look at some weird and wonderful uses for the Wolfram Alpha search engine. (makeuseof.com)
  • These are by no means the only awesome/stupid uses for the Wolfram Alpha search engine. (makeuseof.com)
  • Alpha-1 antitrypsin deficiency (AAT deficiency) is an inherited condition that raises your risk for lung and liver disease. (medlineplus.gov)
  • 5-Alpha-reductase deficiency ( 5-ARD ) is an autosomal recessive intersex condition caused by a mutation of the 5-alpha reductase type 2 gene . (princeton.edu)
  • 5-Alpha-reductase deficiency-2 is biochemically characterized by low to low-normal levels of testosterone and decreased levels of 5α-DHT, creating a higher testosterone/DHT ratio. (princeton.edu)
  • The form used in the human body is alpha tocopherol, and this form is necessary to treat vitamin E deficiency. (news-medical.net)
  • WHEREAS , Alpha-1 Antitrypsin Deficiency (Alpha-1) is one of the most common serious hereditary disorders in the world and can result in life-threatening liver disease in children and adults or lung disease in adults. (michigan.gov)
  • Alpha-1 proteinase inhibitor (Prolastin-C) is a prescription medicine used to treat alpha-1 antitrypsin (AAT) deficiency. (medicinenet.com)
  • There is no cure for AAT deficiency but alpha-1 proteinase inhibitor can help patients manage their condition. (medicinenet.com)
  • What Is Alpha-1 Antitrypsin Deficiency Disorder? (scientificamerican.com)
  • According to Ian Halperin, an investigative journalist who is writing an unauthorized biography of the singer, Jackson, 50, has been fighting the genetically inherited disorder alpha-1 antitrypsin deficiency for several years. (scientificamerican.com)
  • If Jackson has alpha-1 antitrypsin deficiency, it means he cannot protect his lungs from his body's own defenses against bacteria. (scientificamerican.com)
  • The star's older brother Jermaine told Fox News that the singer is not doing well, but on Monday a Jackson rep issued a statement dismissing the alpha-1 antitrypsin deficiency reports as 'total fabrication. (scientificamerican.com)
  • To find out more about the condition, we spoke with James Stoller , a pulmonary critical care doctor at the Cleveland Clinic who has studied alpha-1 antitrypsin deficiency for more than 20 years. (scientificamerican.com)
  • The gastrointestinal bleeding may be unrelated to alpha-1 antitrypsin deficiency, but to the extent that the deficiency is associated with liver and lung disease, one could develop stomach bleeding. (scientificamerican.com)
  • 5-alpha-reductase type 2 deficiency (5-ARD) is an autosomal recessive sex-limited condition resulting in the inability to convert testosterone to the more physiologically active dihydrotestosterone (DHT). (medscape.com)
  • Because DHT is required for the normal masculinization of the external genitalia in utero, genetic males with 5-alpha-reductase type 2 deficiency are born with ambiguous genitalia (ie. (medscape.com)
  • Patients with 5-alpha-reductase type 2 deficiency classically present with striking ambiguity of the genitalia, with a clitoral-like phallus, bifid scrotum, pseudovaginal perineoscrotal hypospadias, and a rudimentary prostate. (medscape.com)
  • The root cause of this disorder is a deficiency in the 5-alpha-reductase type 2 isoenzyme, which transforms testosterone to DHT. (medscape.com)
  • [ 3 ] As with most single enzyme disorders, 5-alpha-reductase type 2 deficiency is autosomal recessive and sex limited because it only causes a clinically significant disorder in genetic males, with very subtle phenotypic changes in homozygous females. (medscape.com)
  • Biochemical effects of 5-alpha-reductase type 2 deficiency in testosterone biosynthesis. (medscape.com)
  • Lack of expression of this gene clinically correlates with the symptoms of 5-alpha-reductase type 2 deficiency. (medscape.com)
  • Linkage analysis has demonstrated that the type 1 enzyme is unrelated to the clinical syndrome of 5-alpha-reductase type 2 deficiency. (medscape.com)
  • Interestingly, partial virilization of males with 5-alpha-reductase type 2 deficiency occurs at puberty and may be attributable to the rise in type 1 enzyme activity or expression at that time. (medscape.com)
  • More than 60 different mutations of the gene for 5-alpha-reductase type 2 have been reported in people with clinical and biochemical evidence of the enzyme deficiency. (medscape.com)
  • ATLANTA -- The Arthritis Foundation today named Alpha Omicron Pi Fraternity (AOII) as the national sponsor of the 2014 Jingle Bell Run/Walk for Arthritis. (arthritis.org)
  • Alpha Omicron Pi was founded in 1897 at Barnard College of Columbia University in New York City. (arthritis.org)
  • Alpha Omicron Pi is an international women's fraternity promoting friendship for a lifetime, inspiring academic excellence and lifelong learning, and developing leadership skills through service to the Fraternity and community. (arthritis.org)
  • To learn more about Alpha Omicron Pi, visit the Fraternity website at www.alphaomicronpi.org , or find AOII online on Facebook and Twitter . (arthritis.org)
  • Alpha-gal allergy is diagnosed by an allergist, or other healthcare provider, through a detailed patient history, physical examination, and a blood test that looks for specific antibodies (IgE antibodies) to alpha-gal. (cdc.gov)
  • The present invention refers to recombinant antibodies of human origin specific for the C5 component of the activated complement and characterised by the ability to inhibit the conversion of the C5 alpha chain to C5a and C5b. (google.com)
  • When alpha-gal enters the body, via a tick bite or otherwise, the immune system produces antibodies to fight the molecule. (medicalnewstoday.com)
  • It remains unclear exactly what substance in the tick's saliva causes the development of alpha-gal antibodies. (medicalnewstoday.com)
  • To determine if alpha-gal antibodies are present in the body, a blood test may be recommended by a doctor. (medicalnewstoday.com)
  • This regulation establishes a tolerance for residues of alpha-cypermethrin in or on food Start Printed Page 73211 commodities/feed commodities in food/feed handling establishments. (federalregister.gov)
  • Although the structures of alphaV1M and HbA, which have been determined by X-ray crystallography, are virtually indistinguishable except at the N-terminal residues, that of alpha+M indicates the displacement of a solvent molecule, possibly a chloride ion, from arginine 141alpha. (rcsb.org)
  • Alpha-gal (galactose-α-1,3-galactose) is a sugar molecule found in most mammals (except in people, apes, and monkeys). (cdc.gov)
  • An alpha-gal allergy is an allergy to the alpha-gal sugar molecule. (cdc.gov)
  • The term alpha-gal is short for galactose-alpha-1, 3-galactose, a carbohydrate molecule that can cause an allergic reaction in people with an alpha-gal allergy. (medicalnewstoday.com)
  • The immune system of people with an alpha-gal allergy treats the alpha-gal molecule in meat as a physical threat to the body. (medicalnewstoday.com)
  • High doses of alpha tocopherol (2000 IU/day) may cause bleeding manifestations in individuals on anticoagulants by interfering with the vitamin K- mediated coagulation cascade. (news-medical.net)
  • Standard Fama-French and Carhart models produce economically and statistically significant nonzero alphas, even for passive benchmark indices such as the S&P 500 and Russell 2000. (nber.org)
  • Alpha provides information about structural and electrophysiological characteristics of individual types of neurons. (wolframalpha.com)
  • The behavior of alpha-synuclein in neurons. (nih.gov)
  • Buildd statistics at https://buildd.debian.org/stats/graph-quarter-big.png and https://buildd.debian.org/stats/graph2-quarter-big.png are also heading the wrong way, and a recent thread on debian-alpha shows that eglibc 2.10 currently fails its testsuite. (debian.org)
  • Retrieved on August 23, 2019 from https://www.news-medical.net/news/20100406/PerkinElmer-expands-No-Wash-ALPHA-Technology-portfolio.aspx. (news-medical.net)
  • [ 1 ] As DHT is a far more potent androgen than testosterone alone, virilisation in those lacking DHT may be absent or reduced compared to males with functional 5-alpha reductase. (princeton.edu)
  • Studies in some primates have shown that some female reproductive strategies , such as cryptic female mate choice , specifically enable reproduction with males other than the alpha male. (everything2.com)
  • The term "alpha" has been used to denote position in social hierarchy, examples being "alpha males" or pack leaders. (wikipedia.org)
  • A useful coefficient for assessing internal consistency is Cronbach's alpha. (bmj.com)
  • Coefficient alpha and the internal structure of tests. (bmj.com)
  • Alpha also stands for thermal expansion coefficient of a compound in physical chemistry. (wikipedia.org)
  • Because it is based on the 3rd generation Prius, the Alpha it is very aerodynamic, with a coefficient of drag (CD) of 0.29. (treehugger.com)
  • L-Alpha glycerylphosphorylcholine ( alpha-GPC , choline alfoscerate ) is a natural choline compound found in the brain. (wikipedia.org)
  • Alpha-olefins are oligomerized at high yields and rapid reaction rates by using a catalyst system comprising titanium halide, an organic halide and a trialkylaluminum compound. (google.com)
  • For people accessing alpha-GPC daily it is advisable to separate a month's supply from excess and storing the excess as best as possible. (wikipedia.org)
  • Allergic reactions typically occur after people eat meat from mammals that have alpha-gal or are exposed to products made from mammals. (cdc.gov)
  • One-Alpha drops contain sorbitol and are not suitable for people with rare hereditary problems of fructose intolerance. (netdoctor.co.uk)
  • Flomax may be no more effective than other alpha-blockers, but the manufacturing company spends more than $100 million marketing it to consumers, so it is often the only BPH drug many people know about. (medicalnewstoday.com)
  • Most people discover they have an alpha-gal allergy after eating red meat. (medicalnewstoday.com)
  • So, people with an alpha-gal allergy do not always associate the reaction with what they have eaten. (medicalnewstoday.com)
  • PerkinElmer, Inc., a global leader focused on the health and safety of people and the environment, today announced the expansion of its 'No Wash' ALPHA (Amplified Luminescent Proximity Homogeneous Assay) Technology portfolio. (news-medical.net)
  • No. 4,041,098, oligomerizes straight chain olefins by forming a first feed containing a low molecular weight alpha-olefin and a soluble aluminum alkyl halide and a second feed containing alpha-olefin and an organic halide. (google.com)
  • 4. The process of claim 1 wherein the alpha-olefin contains from 3 to 14 carbon atoms. (google.com)
  • 8. The process of claim 6 wherein the polymer is a copolymer obtained from alpha-olefins which contain about 6 to about 16 carbon atoms. (google.es)
  • 13. The process of claim 11 wherein the alpha-olefins contain the average carbon sum of from 8 to 12 carbon atoms. (google.es)
  • 18. The process of claim 11 wherein at least one of the alpha-olefins contains from 6 to about 16 carbon atoms. (google.es)
  • 24. The process of claim 22 wherein the alpha-olefin contains from about 6 to about 16 carbon atoms. (google.es)
  • 31. The process of claim 22 wherein the polymer is a copolymer and provided further that at least one alpha-olefin used to obtain the copolymer contains from about 6 to about 16 carbon atoms. (google.es)
  • 1. Know the capital investment required Examine the operating costs & raw materials consumption Alpha-Cyclodextrin is a polysaccharide and a multifunctional, soluble dietary fiber marketed for use as a fiber ingredient, an odor or flavor masking agent, and for emulsification applications. (slideshare.net)
  • For a 10-page description of our methodology, visit www.intratec.us/reports/industrial-processes-economics Reports Focused on Alpha-Cyclodextrin Production Economics ECONOMICS OF ALPHA-CYCLODEXTRIN PRODUCTION FROM CORN (ALPHA-CYCLODEXTRIN E11A) This report presents the economics of alpha-Cyclodextrin production from corn in the USA, using a solvent process. (slideshare.net)
  • Different from the report 'Alpha-Cyclodextrin E11A', the process examined in this report is a non-solvent process. (slideshare.net)
  • 1. A process for preparing a liquid polymer comprising contacting at least one alpha-olefin with a catalyst system comprising at least one secondary organo halide and a Lewis acid catalyst in the presence of a halogenated solvent under polymerization conditions thereby obtaining the liquid polymer. (google.es)
  • 11. A process for preparing an alpha-olefin copolymer comprising contacting at least two alpha-olefins with a catalyst system comprising a secondary organo halide and a Lewis acid catalyst under polymerization conditions employing a halogenated solvent thereby obtaining the alpha-olefin copolymer. (google.es)
  • 22. A process for preparing a polymer comprising contacting at least one alpha-olefin with a catalyst system comprising a secondary organo halide and a Lewis acid catalyst in the presence of a halogenated aprotic solvent at a temperature of about -15 C. to about 25 C. (google.es)
  • Allergy researcher Thomas Platts-Mills of the University of Virginia started studying the alpha-gal reaction in 2002 after discovering an allergic reaction to the cancer drug cetuximab. (medicalnewstoday.com)
  • WHEREAS , Alpha-1 originates in the liver and can lead to liver failure at any time in life. (michigan.gov)
  • WHEREAS , Alpha-1 is widely under diagnosed and misdiagnosed. (michigan.gov)
  • Gamma radiation is electromagnetic radiation, whereas alpha and beta radiation are forms of particulate radiation. (answers.com)
  • The equilibria of oxygen binding to alphaV1M and HbA are similar whereas alpha+M exhibits a significantly higher oxygen affinity. (rcsb.org)
  • Latin / IPA alpha Mathematical / Technical alpha Chambers concise dictionary p.30 Allied Publishers, 2004 ISBN 9798186062363 Retrieved 2017-02-06 Alpha - Definition and More from the Free Merriam-Webster Dictionary Herbert Weir Smyth. (wikipedia.org)
  • This document contains the release notes for FreeBSD 4.5-RELEASE on the Alpha/AXP hardware platform. (freebsd.org)
  • The machine dependent code has been corrected to allow FreeBSD to run on Alphaserver 2100 and 2100A machines based on EV5 Alpha processors. (freebsd.org)
  • This article gives some brief instructions on installing FreeBSD/alpha 5.4-RELEASE, with particular emphasis given to obtaining a FreeBSD distribution. (freebsd.org)
  • You will need a dedicated disk for FreeBSD/alpha. (freebsd.org)
  • However, wealth is not the only alpha male trait that is still in vogue . (everything2.com)
  • The 5-alpha-reductase type 2 isoenzyme is expressed in external genital tissues early in gestation, making its action necessary for the development of normal male external genital anatomy in the fetus. (medscape.com)
  • Flomax is one of a group of drugs called alpha-1 blockers that can help urine flow more easily. (medicalnewstoday.com)
  • Alternative alpha-blockers are available. (medicalnewstoday.com)
  • Other alpha-blockers work in much the same way as Flomax. (medicalnewstoday.com)
  • Both drugs are nonselective alpha-1 blockers, which means they can lower a person's blood pressure. (medicalnewstoday.com)
  • Selective alpha-blockers, such as Flomax, can also lower blood pressure but not quite as much as nonselective alpha-blockers. (medicalnewstoday.com)
  • Alpha-blockers are not the only option for treating BPH. (medicalnewstoday.com)
  • For example, alpha-blockers combined with drugs for an overactive bladder may be more effective. (medicalnewstoday.com)
  • Alpha blockers are drugs used to lower blood pressure. (heart.org)
  • Alpha blockers also lower blood pressure and reduce stress on the heart by slowing the heart rhythm and lessening the force of the heartbeat. (heart.org)
  • These drugs are also called alpha-adrenergic antagonists, alpha-adrenergic blocking agents and alpha-adrenergic blockers. (heart.org)
  • We find that these alphas arise primarily from the disproportionate weight the Fama-French factors place on small value stocks, which have performed well, and from the CRSP value-weighted market index, which is historically a downward-biased benchmark for U.S. stocks. (nber.org)
  • You don't want to be rushed while you're trying to find your alpha state of mind, particularly if it's your first time. (wikihow.com)
  • To find the alpha state of mind, you need to be focused on your meditations. (wikihow.com)
  • Proper storage methods need to be used with alpha-GPC and include removing all air from the container, double bagging with plastic bags rated for chemicals (less likely to leak air), and storing bulk/excess inside the freezer. (wikipedia.org)
  • Tocopherols are found in almost all plant seeds, the best sources of alpha-tocopherol include plant seeds such as almonds, sunflower seeds and hazelnuts. (news-medical.net)
  • If we reach this goal, we will include an extended bestiary of mutant monsters that can be used in both Mutant: Genlab Alpha and Mutant: Year Zero . (kickstarter.com)
  • Letters that arose from alpha include the Latin A and the Cyrillic letter А. (wikipedia.org)
  • The 28 new offerings include 9 AlphaScreen® SureFire ® and 19 AlphaLISA® 'No-Wash' immunoassay kits, bringing the combined number of ALPHA-based kits to 174 assays. (news-medical.net)
  • Alpha Chi Sigma is a co-ed professional fraternity specializing in the chemical sciences. (umich.edu)
  • Natural vitamin E includes four tocopherols, called alpha, beta, gamma and delta tocopherol respectively. (news-medical.net)
  • The Alpha Beta chapter at the University of Michigan was founded in 1916 and continues to uphold the traditions of our founding brothers. (umich.edu)
  • There are 2 main types of thalassemia: alpha and beta. (hopkinsmedicine.org)
  • Gamma comes as a result of alpha or beta. (answers.com)
  • Gammas covers a bigger area than beta and alpha and is in that way more dangerous, but if you ever get alpha radiation inside of you, that is very dangerous. (answers.com)
  • Of alpha, beta and gamma radiation, gamma radiation has the greater ability to penetrate either shielding or living tissue. (answers.com)
  • The penetration issue aside, a contact source that is an alpha emitter can do more tissue damage than beta or gamma radiation. (answers.com)
  • Alpha and beta radiation are particulate radiation. (answers.com)
  • Your brain begins to emit alpha waves instead of beta, which is what you emit when you're fully awake. (wikihow.com)
  • Despite extensive purification, functional homogeneity of the E. coli expressed hemoglobin was achieved only by the complete disassembly of the hemoglobin into its component alpha and beta globins and their reassembly in the presence of hemin. (rcsb.org)
  • 1988 ). It serves as the non-signaling alpha-receptor of the multifunctional cytokine IL-6 and is expressed in a cell-type-specific manner. (springer.com)
  • Alpha Ebot is to implement a software to interact with robots, this software using the bluetooth BLE protocol to transmit control command, implementation and robot interaction, let robot singing and dancing, tai chi, etc. (apple.com)
  • Which drugs or supplements interact with alpha-1-proteinase inhibitor-injection? (medicinenet.com)
  • It is hypothesized that rising testosterone levels at the start of puberty (around age twelve) are able to generate sufficient levels of DHT either by the action of 5-alpha-reductase type 1 (active in the adult liver, non-genital skin and some brain areas) or through the expression of low levels of 5-alpha-reductase type 2 in the testes. (princeton.edu)
  • You have a greater risk of having a child with the most severe type, alpha thalassemia major. (hopkinsmedicine.org)
  • This condition causes mild to severe anemia, based on the type of alpha thalassemia that is inherited. (uhhospitals.org)
  • The type I IFNs bind to the interferon alpha receptor (IFNAR), which consists of two subunits, IFNAR1 (α-subunit) and IFNAR2 (β-subunit). (rug.nl)
  • In adulthood, the 5-alpha-reductase type 2 isoenzyme is expressed in high levels in the prostate, genital skin, epididymis, seminal vesicle, and liver. (medscape.com)
  • Greek alpha / Coptic alfa For accented Greek characters, see Greek diacritics: Computer encoding. (wikipedia.org)
  • The Alpha Sigma Nu Jesuit Book Awards , established in 1979, recognize outstanding publishing achievement at Jesuit colleges and universities. (bc.edu)
  • Studies have investigated the efficacy of alpha-GPC for cognitive disorders including stroke and Alzheimer's disease . (wikipedia.org)
  • Due to the lack of conclusive safety data, alpha-1 proteinase inhibitor should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. (medicinenet.com)
  • Alpha-tocopherol esters in supplements are chiefly succinate and acetate, and these are converted to alpha-tocopherol in the intestine before absorption. (news-medical.net)
  • Alpha-gal allergy is chiefly spread by the bite of the Lone Star tick, so named for the marking on its back. (medicalnewstoday.com)
  • Alpha-gal can be found in products made from mammals (including some medications, cosmetics, vaccines, gelatin, and milk products). (cdc.gov)
  • In English, the noun "alpha" is used as a synonym for "beginning", or "first" (in a series), reflecting its Greek roots. (wikipedia.org)