• After pretreatment with a subconvulsant dose of allylglycine (180-200 mg/kg), lysergic acid diethylamide, 0.1 mg/kg, retained the capacity to block myoclonic responses to IPS, and ergocornine 1 mg/kg reduced such responses. (springer.com)
  • We studied the effects of chronic (7 day) infusions of GABA (100 and 20 micrograms/microliter, 10 microliter/h) applied in different cerebral structures of baboons made photosensitive by a subconvulsant dose of allylglycine. (statescale.cf)
  • These were prepared via key intermediates containing internal allylglycine and allyltyrosine residues for subsequent ring closing metathesis reactions. (edu.au)
  • This was prepared via key intermediates containing an internal allylglycine and an allyl-substituted binaphthyl unit for a subsequent ring-closing metathesis reaction. (edu.au)
  • Horton, R. W., Meldrum, B. S.: Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase. (springer.com)
  • This synthesis could also be completed for glutamic acid to obtain homo-allylglycine as well. (virginia.edu)
  • Rats were fitted with femoral arterial and venous catheters and implanted with Alzet pumps infusing the GABA synthesis inhibitor L-allylglycine into the DMH. (elsevier.com)
  • Este efecto fue similar al observado agregando al medio agonistas GABA-A y B. Conclusiones: la activación peripuberal del sistema GABAérgico frena el eje reprodutor, produciendo un retraso en el desarrollo. (bvsalud.org)
  • Esto podría atribuirse a la existencia, en esta etapa, de interrelaciones fisiológicas entre los aminoácidos que regulan la secreción de GnRH (GABA, glutamato, taurina). (bvsalud.org)
  • Allylglycine is known to induce seizures in animals studies, presumably due to this GDC-inhibiting activity. (wikipedia.org)
  • This paper describes a concise synthesis of spiropyrrolidines and spiropiperidines which employs a ruthenium-alkylidene-catalysed cross-metathesis reaction of enantiopure N -protected allylglycine with methylenecycloalkanes. (andrearobinsongroup.com)
  • In contrast, chymotrypsin was able to use allylglycine ethyl ester (DL-AgOEt) as the acyl acceptor in the synthesis of Cbz-L-Phe-L-AgOEt, but was not able to synthesize Cbz-L-Ag-L-PheNH2. (denypage.info)
  • Allylglycine is a glycine derivative. (wikipedia.org)
  • Unsaturated α-amino acids in homochiral form were obtained using the Ramberg-Bäcklund reaction as the key step.117 The method is illustrated by the conversion of methionine into allylglycine (as its Boc, tert-butyl ester derivative) in optically enriched form (Scheme 78). (booncafe.com)
  • Stimuli-Responsivity of Secondary Structures of Glycopolypeptides Derived from Poly(L-glutamate-co-allylglycine). (mpg.de)
  • Swelling behavior of chemically cross-linked poly(N-IPAAm-allylglycine) hydrogels: Effects of NaCl and pH. (uni-kl.de)
  • In her previous role as senior scientist at the University of Leuven, Belgium, Dr. Esguerra and collaborators (in both industry and academia) generated a pharmacoresistant seizure model in both mice and zebrafish using the proconvulsant allylglycine. (uio.no)