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  • biopsy
  • A diagnosis of Waldenström's macroglobulinemia depends on a significant monoclonal IgM spike evident in blood tests and malignant cells consistent with the disease in bone marrow biopsy samples. (wikipedia.org)
  • Diagnosis is typically made by blood tests or bone marrow biopsy. (wikipedia.org)
  • malignant
  • Allogeneic BMT is also curable therapy for non-malignant diseases that affect blood cells, including aplastic anemia and other autoimmune disorders, as well as inherited diseases such as hemoglobinopathies and immunodeficiencies. (oncologynurseadvisor.com)
  • 1 Frequent neurological sequelae in the early period after allogeneic BMT include encephalopathy, cerebrovascular accidents, central nervous system (CNS) infections, and recurrence of the malignant disease. (ahajournals.org)
  • Lymphocytes
  • von Boehmer, H., Hudson, L. and Sprent, J.: Collaboration of histo-incompatible T and B lymphocytes using cells from tetraparental bone manow chimeras. (wikipedia.org)
  • von Boehmer, H. and Haaso W.: Cytotoxic T lymphocytes recognize allogeneic toleruted, TNP-conjugated cells. (wikipedia.org)
  • cancers
  • Myelodysplastic syndromes (MDS) are a group of cancers in which immature blood cells in the bone marrow do not mature and therefore do not become healthy blood cells. (wikipedia.org)
  • stem cell
  • When this mutation occurs in a hematopoietic stem cell in the bone marrow, all of the cells it produces will also have the defect. (wikipedia.org)
  • In recognition of his research accomplishments and leadership in moving basic science discoveries in stem cell biology into the clinic, he was elected President of the International Society of Cellular Therapy (1995-1997), Treasurer of the Foundation for the Accreditation of Cellular Therapy (1995-2002) and President of the American Society of Blood and Marrow Transplantation (1999-2000). (wikipedia.org)
  • transplants
  • Globally, pioneering experimental studies in the surgical technique of human organ transplantation were made in the early 1900s by the French surgeon Alexis Carrel, and successful transplants starting spreading worldwide after the Second World War. (wikipedia.org)
  • cells
  • Bone marrow is the place for the production of the hematopoietic cells which differentiate in to three groups: red blood cells, white blood cells and platelets. (omicsonline.org)
  • Hematopoietic stem cells (HSCs) are very rare cells, representing approximately one in 100,000 bone marrow (BM) cells in the adult. (omicsonline.org)
  • Bone marrow aspirate revealed 24% plasma cells with abnormal morphology. (wiley.com)
  • In this study, we investigated the feasibility and safety of intravenous transplantation of allogeneic bone marrow mesenchymal stem cells (MSCs) for femoral head repair, and observed the migration and distribution of MSCs in hosts. (medsci.org)
  • Researchers have transplanted the bone marrow stem cells into the necrotic femoral heads, and results show bone marrow stem cells can remove vascular lesions and promote angiogenesis in necrotic femoral heads, accompanied by significant improvement of blood circulation in the necrotic femoral head and surrounding tissues [ 4 ]. (medsci.org)
  • The crowding that results from such cells makes the bone marrow unable to produce healthy blood cells. (wikipedia.org)
  • In Gunther's disease, porphyrins are accumulated in the teeth and bones and an increased amount are seen in the plasma, bone marrow, feces, red blood cells, and urine. (wikipedia.org)
  • Some types have an increase in immature blood cells, called blasts, in the bone marrow or blood. (wikipedia.org)
  • The types of MDS are based on specific changes in the blood cells and bone marrow. (wikipedia.org)
  • The outlook depends on the type of cells affected, the number of blasts in the bone marrow or blood, and the changes present in the chromosomes of the affected cells. (wikipedia.org)
  • Methods
  • Diagnostic methods include blood analysis, bone marrow aspirate for cytochemical, immunological and cytogeneticalanalysis, and cerebrospinal fluid (CSF) investigations. (wikipedia.org)
  • 2002
  • In 2002, doctors at Xijing Hospital of the Fourth Military Medical University described three cases of living related liver transplantation. (wikipedia.org)
  • liver
  • In rabbits, at 6 w after intravenous transplantation, GFP labeled MSCs were noted in the lungs, liver, bone marrow and normal and necrotic femoral heads of rabbits, and the number of MSCs in bone marrow was higher than that in the, femoral head, liver and lungs. (medsci.org)
  • studies
  • As a physician-scientist, van den Brink studies allogeneic bone marrow transplantation both in the clinic and the laboratory. (wikipedia.org)
  • Working under the supervision of Bruce (AACR Award), and in association with Till and McCulloch and a vibrant group of graduate students and post-doctoral fellows, Eaves completed his PhD in Medical Biophysics at the University of Toronto with a thesis entitled Studies on the Control of Murine Bone Marrow Function (1974). (wikipedia.org)