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  • retrospective
  • In this retrospective national study, we have reviewed the outcome after HSCT in Sweden for adult Ph-positive ALL between 2000 and 2009. (diva-portal.org)
  • vivo
  • We produced an endothelium-targeted soluble Notch ligand, the Delta-Serrate-Lag-2 (DSL) domain of human Delta-like 1 fused with a RGD motif (hD1R), and tested the effects of this protein on human umbilical cord blood hematopoietic stem and progenitor cell (UCB-HSPC) ex vivo and in vivo. (biomedcentral.com)
  • Two- or three-antigen mismatched related HSCT without ex vivo T-cell depletion has been investigated in Japan using a variety of strategies including in vivo T-cell depletion using anti-thymocyte globulin or alemtuzumab, and its safety has become close to that of HLA-matched HSCT. (go.jp)
  • systemic
  • The data provided in the NDA submission demonstrate that orBecĀ® may provide a higher rate of survival when compared with the current standard of care, and a lowered exposure to systemic corticosteroids following allogeneic transplantation. (marketwired.com)
  • transfusion
  • Treatment of thrombopathy requires, first of all symptomatic measures: haemostatic glues, desmopressin and the blood transfusion which must be only reserved for the difficult gestures or for the high hemorrhagic risk. (omicsonline.org)
  • immune system
  • HSCs are characterized by their unique ability to self-renew and give rise to the entirety of the blood and immune system throughout the lifetime of an individual. (omicsonline.org)
  • Allo-HSCT is associated with a more severe derangement of the immune system than auto-HSCT. (springer.com)
  • chronic
  • In chronic myeloid leukemia (CML), HSCT which is once the mainstay for cure is now largely supplemented by molecularly targeted therapy. (omicsonline.org)
  • Chronic myeloid Leukemia is one of the most common types of blood cancer. (medindia.net)
  • recover
  • Watch the recorded webinar to hear Linda Peltier, research associate at McGill University, discuss how new compliance regulations impact public cord blood banks, why the current operational model must be modified, and ways to recover cord blood and tissue components for a better operational cost. (mediware.com)
  • This presentation discusses ways to recover cord blood and tissue components for a better operational cost. (mediware.com)
  • McGill's bank was able to recover more than 85% of units rejected by the public bank and calculated that making available cord blood plasma for MSC culture could double the revenue of the bank. (mediware.com)
  • initially
  • Lucarelli and his colleagues at Pesaro initially pioneered HSCT in thalassemia and described a standard 'Pesaro' risk stratification scheme based on liver size by physical examination, fibrosis detected on liver biopsy, and chelation history. (clinicaltrials.gov)