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MonobactamsAnti-Bacterial Agentsbeta-LactamasesCeftazidimeMicrobial Sensitivity Testsbeta-LactamsCephalosporinsPseudomonas aeruginosaPseudomonas Infectionsbeta-Lactam ResistanceCefoperazoneGram-Negative BacteriaKlebsiella pneumoniaeEnterobacterAmikacinAzlocillinImipenemEnterobacteriaceaeEnterobacteriaceae InfectionsCephalosporinaseTobramycinPiperacillinIsoelectric FocusingDrug Resistance, MicrobialCefotaximeClavulanic AcidSkin Diseases, BacterialKlebsiella InfectionsCarbapenemsThienamycinsKlebsiellaCitrobacterAzabicyclo CompoundsEscherichia coliAmdinocillinSerratia marcescensCephalosporin ResistanceCefoxitinSerratia InfectionsGentamicinsEnterobacter cloacaeDrug Resistance, Multiple, BacterialDrug Resistance, BacterialBacterial InfectionsTicarcillinKineticsCystic FibrosisHalf-LifeCefuroximeDrug Therapy, CombinationProteus vulgarisGram-Negative Aerobic BacteriaPenicillinsBacteriaGram-Positive BacteriaVancomycinClavulanic AcidsAcinetobacterAminoglycosidesKanamycinConjugation, GeneticProteus mirabilisLactamsSalmonella paratyphi APlasmidsHydrolysisMuramoylpentapeptide CarboxypeptidaseDNA, BacterialPenicillanic AcidGram-Negative Bacterial InfectionsPenicillin-Binding ProteinsBacteria, AerobicChromatography, High Pressure LiquidCiprofloxacinHexosyltransferasesParatyphoid FeverSulbactamFecesBileBacterial ProteinsAcinetobacter baumanniiInfusions, ParenteralPeptidyl TransferasesEscherichia coli InfectionsColistinDrug SynergismMolecular Sequence DataRabbitsMeningitis, HaemophilusBacteria, AnaerobicInjections, IntramuscularAztreonamAmpicillinMacaca fascicularisMinocyclineIntegronsDrug StabilityPenicillinaseAdministration, InhalationEndocarditis, Bacterial
AzactamBeta-lactam antiReactionsAntibioticAntibioticsCephalosporinsInjectionRashCeftazidimeAvibactamAnaphylaxisRhinitisPenicillin-allergicPatientsImipenemInfectionsCefoxitinBacterialAllergyProteusAntagonismDrugsCaystonClindamycinInfectionPseudomonasPregnancyPneumoniaIngredientsAdverseTreatmentAcceptableMedical
Azactam4
  • Aztreonam, sold under the brand name Azactam among others, is an antibiotic used primarily to treat infections caused by gram-negative bacteria such as Pseudomonas aeruginosa. (wikipedia.org)
  • Aztreonam is poorly absorbed when given orally, so it must be administered as an intravenous or intramuscular injection (trade name Azactam), or inhaled (trade name Cayston) using an ultrasonic nebulizer. (wikipedia.org)
  • AZACTAM ® (aztreonam for injection, USP) delivers proven efficacy in the management of certain Gram-negative infections. (bmscustomerconnect.com)
  • AZACTAM ® (aztreonam for injection, USP) should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. (bmscustomerconnect.com)
Beta-lactam anti8
  • Because of the unfused beta-lactam ring there is somewhat lower cross-reactivity between aztreonam and many other beta-lactam antibiotics, and it may be safe to administer aztreonam to many patients with hypersensitivity (allergies) to penicillins and nearly all cephalosporins. (wikipedia.org)
  • There is a much lower risk of cross-sensitivity between aztreonam and other beta-lactam antibiotics than within other beta-lactam antibiotics. (wikipedia.org)
  • Certain antibiotics (eg, cefoxitin, imipenem) may induce high levels of beta-lactamase in vitro in some Gram-negative aerobes such as Enterobacter and Pseudomonas species, resulting in antagonism to many beta-lactam antibiotics including aztreonam. (pfizermedicalinformation.com)
  • Aztreonam is commonly used to treat people who are allergic to some beta-lactam antibiotics and is used in combination with other antibiotics to treat certain antibiotic-resistant bacteria. (msdmanuals.com)
  • Like the other beta-lactam antibiotics, aztreonam works by preventing bacteria from forming this cell wall, resulting in death of the bacteria. (msdmanuals.com)
  • ERIPOD 50MG DRY SYRUP should be avoided if you are allergic to cefpodoxime or to the cephalosporin group of antibiotics (such as cefuroxime, cefixime) or if you had experienced immediate or severe hypersensitivity reaction (anaphylaxis) to penicillin or other beta-lactam antibiotics (such as aztreonam). (netmeds.com)
  • Aztreonam Aztreonam is the only antibiotic in an antibiotic class called monobactams, which are a subclass of beta-lactam antibiotics (antibiotics that have a chemical structure called a beta-lactam ring). (merckmanuals.com)
  • Because of a beta-lactam ring in their structure, they are called beta-lactam antibiotics, along with these other medications, cephalosporins, carbapenems, and aztreonam. (picmonic.com)
Reactions5
  • Serious side effects include Clostridium difficile infection and allergic reactions including anaphylaxis. (wikipedia.org)
  • The allergic reactions included a serious rash and skin conditions such as StevensJohnson syndrome a life threatening rash that causes painful blisters. (njacs.org)
  • Palpable purpura also can produce transient ventilatory depression may have allergic or other unpredictable reactions to aztreonam because aztreonam and ceftazidime have a concave appearance and jump-start their endogenous development. (elastizell.com)
  • Severe allergic reactions have been reported following administration of aztreonam for injection to patients with no known history of exposure to aztreonam. (caystonhcp.com)
  • Severe allergic reactions. (cayston.com)
Antibiotic3
  • The combination antibiotic consists of aztreonam, a monobactam β-lactam and avibactam, a broad-spectrum β-lactamase inhibitor. (empr.com)
  • The investigational antibiotic combination aztreonam-avibactam was found to be effective for treating serious bacterial infections caused by Gram-negative bacteria, according to findings from two phase 3 studies. (empr.com)
  • NCT03580044 ) studies were conducted to evaluate the efficacy and safety of the novel antibiotic combination, which consists of a monobactam β-lactam (aztreonam) and a broad-spectrum β-lactamase inhibitor (avibactam). (empr.com)
Antibiotics6
  • The newer generation cephalosporin antibiotics have different R1-side chains making the cross-reactivity low and likelihood of allergic reaction even lower compared to some of the first generation agents and penicillin. (ebmconsult.com)
  • Necrotizing pneumonia was diagnosed, and the patient was started on broad-spectrum antibiotics (aztreonam and clindamycin) to cover all Gram-positive and Gram-negative organisms, pending the outcome of the sputum and blood cultures. (rcjournal.com)
  • These in vitro findings suggest that such beta-lactamase inducing antibiotics not be used concurrently with aztreonam. (pfizermedicalinformation.com)
  • Some people are allergic to certain antibiotics. (merckmanuals.com)
  • Aztreonam is in a class of medications called monobactam antibiotics. (alvislabs.com)
  • We believe these data demonstrate that [aztreonam-avibactam], if approved, could be an important treatment option for patients with life-threatening bacterial infections that are resistant to almost all currently available antibiotics," said James Rusnak, Senior Vice President and Chief Development Officer, Internal Medicine, Anti-Infectives and Hospital, Pfizer. (empr.com)
Cephalosporins2
Injection9
  • tell your doctor and pharmacist if you are allergic to chloramphenicol injection or any other medications. (medlineplus.gov)
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of Aztreonam for Injection, USP and other antibacterial drugs, aztreonam for injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. (pfizermedicalinformation.com)
  • Aztreonam for Injection is indicated for adjunctive therapy to surgery in the management of infections caused by susceptible organisms, including abscesses, infections complicating hollow viscus perforations, cutaneous infections, and infections of serous surfaces. (pfizermedicalinformation.com)
  • Aztreonam for Injection is effective against most of the commonly encountered Gram-negative aerobic pathogens seen in general surgery. (pfizermedicalinformation.com)
  • Concurrent initial therapy with other antimicrobial agents and aztreonam for injection is recommended before the causative organism(s) is known in seriously ill patients who are also at risk of having an infection due to Gram-positive aerobic pathogens. (pfizermedicalinformation.com)
  • Aztreonam for Injection may be administered intravenously or by intramuscular injection. (pfizermedicalinformation.com)
  • Manufacturer of a wide range of products which include aztreonam injection 500 mg, aztreonam 1gm injection and aztrack 250mg azetreonam. (alvislabs.com)
  • Aztreonam injection is used to treat certain infections that are caused by bacteria, including respiratory tract (including pneumonia and bronchitis), urinary tract, blood, skin, gynecological, and abdominal (stomach area) infections, that are caused by bacteria. (alvislabs.com)
  • Aztreonam injection also may be used before, during, and sometimes for a brief period after surgery in order to prevent the patient from getting an infection. (alvislabs.com)
Rash3
  • In addition, allergic reaction with facial rash, facial swelling, and throat tightness was reported with CAYSTON in clinical trials. (caystonhcp.com)
  • An allergic reaction can range from a rash to anaphylaxis. (picmonic.com)
  • Stop your treatment with CAYSTON and call your healthcare provider right away if you have any symptoms of an allergic reaction, including rash or swelling of your face, or throat tightness. (cayston.com)
Ceftazidime3
Avibactam8
  • The combination of aztreonam and avibactam are in phase 3 clinical trails. (wikipedia.org)
  • The combination of aztreonam and avibactam has demonstrated to be active against 80% of MBL isolates reaching a clinical infection resolution in 80% of MBL-infected patients. (wikipedia.org)
  • Study participants were randomly assigned to receive aztreonam-avibactam ± metronidazole or meropenem ± colistin. (empr.com)
  • The clinical cure rates in the intention-to-treat analysis sets were reported to be 76.4% (95% CI, 70.3-81.8) and 45.9% (95% CI, 34.9-57.3) among patients with cIAI and HAP/VAP treated with aztreonam-avibactam ± metronidazole, respectively. (empr.com)
  • Among cIAI patients, the all-cause mortality rates were 1.9% with aztreonam-avibactam ± metronidazole vs 2.9% with meropenem ± colistin. (empr.com)
  • Among those with HAP/VAP, the all-cause mortality rates were 10.8% and 19.4% in the aztreonam-avibactam ± metronidazole and meropenem ± colistin groups, respectively. (empr.com)
  • These findings were further supported by results from the ASSEMBLE study, which included 15 adult patients and compared aztreonam-avibactam to best available therapy. (empr.com)
  • Findings from REVIST and ASSEMBLE will form the basis of the regulatory submission for aztreonam-avibactam. (empr.com)
Anaphylaxis1
  • Anaphylaxis - Epinephrine auto-injectors (EpiPen's) are used for emergency situations of allergic reaction or anaphylaxis. (leftseat.com)
Rhinitis3
  • NAR should be distinguished from those rhinitis patients with an allergic reaction confined to the nasal mucosa, also called entopy or local allergic rhinitis (LAR). (influscience.eu)
  • The use of a mask is recommended for conditions such as allergic rhinitis. (selfdecode.com)
  • Corticosteroids are usually indicated in the following conditions EXCEPT: A. Herpes simplex of the eye B. Status asthmaticus C. Severe allergic rhinitis D. Nephrotic syndrome E. Adrenal insufficiency 22. (kupdf.net)
Penicillin-allergic1
Patients3
  • The changing R1-side chains lowers the cross-reactivity and further lowers the chance for an allergic reaction in patients with reported penicillin allergy. (ebmconsult.com)
  • CAYSTON is contraindicated in patients with a known allergy to aztreonam. (caystonhcp.com)
  • Erythromycin, a macrolide, is an acceptable alternative to penicillin for patients who have bacterial infections and are allergic to penicillin. (easynotecards.com)
Imipenem1
Infections1
Cefoxitin1
Bacterial1
  • Aztreonam inhibits cell wall synthesis by blocking peptidoglycan crosslinking to cause bacterial death. (wikipedia.org)
Allergy1
Proteus1
Antagonism3
  • aztreonam decreases effects of BCG vaccine live by pharmacodynamic antagonism. (medscape.com)
  • aztreonam decreases effects of microbiota oral by pharmacodynamic antagonism. (medscape.com)
  • aztreonam decreases effects of typhoid vaccine live by pharmacodynamic antagonism. (medscape.com)
Drugs1
  • Which of the following drugs should a provider prescribe for a patient who has streptococcal pharyngitis and is allergic to penicillin? (easynotecards.com)
Cayston2
  • If an allergic reaction occurs, stop administration of CAYSTON and initiate treatment as appropriate. (caystonhcp.com)
  • Do not take CAYSTON if you are allergic to aztreonam, or any of the ingredients in CAYSTON. (cayston.com)
Clindamycin1
  • The diagnosis was revised to necrotizing pneumonia due to GCBHS, and treatment with intravenous aztreonam and clindamycin were continued. (rcjournal.com)
Infection1
  • Aztreonam, while your infection is healing, read more. (njacs.org)
Pseudomonas1
Pregnancy1
  • Aztreonam should be taken during pregnancy only when the benefits of treatment outweigh the risks. (msdmanuals.com)
Pneumonia1
  • Since the patient was allergic to penicillin, intravenous levofloxacin was initiated for treatment of the pneumonia. (rcjournal.com)
Ingredients1
  • Do not use ventolin HFA if you are allergic to albuterol sulfate or any of the ingredients in ventolin HFA. (njacs.org)
Adverse1
  • I asked because I know for a fact that her wife is allergic to cats Finally, it is new that the fine T reports for UTIs way of adverse health works may be warned because of bacteria demanded to use misuse. (dagoddess.com)
Treatment1
  • Data from both trials also showed that the combination treatment was well tolerated and had a similar safety profile to aztreonam alone . (empr.com)
Acceptable1
Medical1
  • Aztreonam was approved for medical use in the United States in 1986. (wikipedia.org)