Allergic lung inflammation. Medical search. Frequent questions

To test this hypothesis, the frequency of metastasis to the lung as a function of allergic pulmonary inflammation was assessed following the i.v. injection of B16-F10 melanoma cells in mice. (elsevierpure.com)
Thus, our data show that allergic respiratory inflammation may represent a risk factor for the development of lung metastases and suggest that amelioration of the pulmonary inflammation associated with asthma will have a direct and immediate benefit to the 7% to 8% of breast cancer patients with this lung disease. (elsevierpure.com)
She continued her interest in allergens, looking at the roles for cells and molecules involved in pulmonary inflammation. (wikipedia.org)
Pulmonary exposure to NQ dose-dependently aggravated antigen-related airway inflammation, as characterised by infiltration of eosinophils and lymphocytes around the airways and an increase in goblet cells in the bronchial epithelium. (ersjournals.com)
DEP have been correlated to lung cancer, pulmonary fibrosis, chronic alveolitis 1 and oedematous changes 2 . (ersjournals.com)
While primary care providers can diagnose and treat asthma, consultation with a specialist, such as an allergist or pulmonary or lung specialist, may be necessary. (healthywomen.org)
Pulmonary or lung function testing is essential to making the proper diagnosis. (healthywomen.org)
Here, we mechanistically investigated pulmonary inflammation and lung function decline after inhalation co-exposure and individual exposures to ozone (O(3)) and ultrafine carbon black (CB). (cdc.gov)

Stop using STELARA ® and get medical help right away if you have any symptoms of a serious allergic reaction such as: feeling faint, swelling of your face, eyelids, tongue, or throat, chest tightness, or skin rash. (healthgrades.com)
ever had an allergic reaction to STELARA ® or any of its ingredients. (healthgrades.com)
3. Asthma attacks can be caused by a person coming into contact with something their asthma is sensitive to, called an "allergen", which causes an allergic reaction in the form of asthma symptoms. (funtrivia.com)
It is characterized by inflammation and constriction of the airways in reaction to allergens or irritants that are inhaled into the lungs, making it difficult to breathe. (cdc.gov)
Allergic rhinitis usually presents in early childhood and is caused by an immunoglobulin E (IgE)-mediated reaction to various indoor and outdoor allergens. (medscape.com)
In the case of allergic rhinitis, the reaction takes place in the nasal passages. (medscape.com)
The reaction is the same for all allergic reactions. (medscape.com)
These therapies can also cause a severe, sometimes fatal, allergic reaction in people sensitive to certain ingredients in the treatment. (medlineplus.gov)
Fungus was found in his blood and lungs, with such severe inflammation suggesting an allergic reaction to it, he said. (sky.com)
Eating particular foods before exercising may bring on an allergic reaction. (healthline.com)
The allergic reaction can cause airways to inflame, to the point of closing up and blocking airflow to the lungs. (healthline.com)
It injects epinephrine into your system to slow the allergic reaction. (healthline.com)
The auto-injector isn't a cure in itself, it just slows the allergic reaction, so be sure to go to the hospital immediately after using it. (healthline.com)
When the body is combating to an allergic reaction by something like in case of skin allergy that results in symptoms of eczema. (planetayurveda.com)
B. An allergic or unexpected reaction. (jotform.com)
Anaphylaxis Anaphylaxis is an acute, potentially life-threatening, IgE-mediated allergic reaction that occurs in previously sensitized people when they are reexposed to the sensitizing antigen. (msdmanuals.com)

She established the Lung Immunology Group on the South Kensington campus of Imperial College London to study immune mechanisms in infectious and allergic lung inflammation and remodelling. (rbht.nhs.uk)
Dr Boyton is head of the Lung Immunology Group in the section of infectious disease and immunity, department of medicine, Imperial College London. (rbht.nhs.uk)
Prof. Rosemary Boyton is Head of Lung Immunology, Adult Infectious Disease, Department of Infectious Disease, Faculty of Medicine. (imperial.ac.uk)
Prof. Boyton works on the molecular immunology of infectious, allergic and autoimmune inflammation through patient based studies and TCR, HLA class II, lung targeted, inducible (Cre/Lox) and reporter transgenic models. (imperial.ac.uk)

There are other factors which can trigger asthma attacks, which are described as being "irritant" to the airways rather than causing a true allergic response. (funtrivia.com)
Asthma is a chronic lung condition in which patients have inflammation and tightening of the airways . (springfieldclinic.com)
Asthma is caused by inflamed airways, which makes them sensitive to inhaled particles, generating more inflammation. (mariasfarmcountrykitchen.com)
While these medications are often necessary, I like to explore more holistic approaches to controlling inflammation and decreasing the airways' sensitivity to inhaled particles. (mariasfarmcountrykitchen.com)
Asthma is a lung condition that makes the primary airways-known as the bronchi-in the lungs swollen and inflamed all of the time. (healthywomen.org)
Asthma is a lung condition that results in the large and small airways-known as the bronchi and bronchiole-in the lungs becoming swollen and inflamed. (healthywomen.org)
The airways can swell as a result of inflammation made worse by an elevated number of a type of white blood cells known as eosinophils, which are markers for severe asthma. (healthywomen.org)
In people exposed to tobacco smoke or other inhaled irritants the movement of the small hairs is reduced, mucus production increases, lung cleansing is diminished, and the airways narrow. (healthy.net)

The history of the patient with allergic rhinitis is usually straightforward, but at times may have a complex set of symptoms. (medscape.com)
No laboratory studies are needed in allergic rhinitis if the patient has a straightforward history. (medscape.com)
The history of the patient with allergic rhinitis may be straightforward or may include a complex set of symptoms. (medscape.com)
Perform a full examination to detect other diseases, such as adenoidal hypertrophy, asthma, eczema, and cystic fibrosis, which occur in children in connection with allergic rhinitis. (medscape.com)
In general, imaging studies are not needed in pediatric allergic rhinitis unless sinusitis is suspected. (medscape.com)
Co-morbidities of asthma include sinusitis, nasal polyposis, gastro-esophageal reflux disease (GERD) and allergic rhinitis. (medscape.com)

Also, DEP have been implicated to modulate allergic reactions 3 , 4 . (ersjournals.com)
1-4) ROS react with cells initiating chain reactions that result in tissue damage causing inflammation, spasm, pain and disease. (life-enthusiast.com)
It helps to reduce allergic, inflammatory, histaminic reactions congestion and secretions. (planetayurveda.com)
Green tea is very much helpful in allergic reactions that are caused by pollen,dust, pet dander, certain forms of chemicals. (planetayurveda.com)
Green tea inhibits the production of chemicals that are involved in formation of allergic reactions. (planetayurveda.com)
If severe, allergic reactions might cause more serious respiratory (lung) or cardiovascular (heart) problems which may require treatment. (jotform.com)
Allergic (including atopic) and other hypersensitivity disorders are inappropriate or exaggerated immune reactions to foreign antigens. (msdmanuals.com)
and Enterococcus faecalis ) and pathologic growth around the prosthetic joint ( 15 ), aseptic implant loosening results from chronic inflammation caused by activation of resident immune cells in contact with implant wear debris or allergic reactions to metal ions derived from implant materials ( 16 ). (cdc.gov)

However, people with weakened immune systems or lung diseases are at a higher risk of developing health problems due to Aspergillus . (cdc.gov)
These studies suggest that quinones may be key compounds in the enhancing effects of DEP on allergic airway diseases. (ersjournals.com)
Dysbiosis in gut microbiota has been implicated in several lung diseases, including allergy, asthma and cystic fibrosis. (frontiersin.org)
The bi-directional cross-talk between gut and lung (termed as Gut-Lung axis) is best exemplified by intestinal disturbances observed in lung diseases. (frontiersin.org)
In this review, we focus on the recent developments related to influence of diet on this "Gut-Lung axis" as well as discuss the impact of different types of diet on gut microbiota and how they influence lung immunity as well as lung diseases. (frontiersin.org)
A Tale of Two Cases in Allergic Diseases: How Will You Treat These Patients With Asthma and Chronic Spontaneous Urticaria? (medscape.com)
which in turn promotes T helper lymphocyte Th2 responses and stimulates the formulation of immunoglobulin E. As dietary fat intake patterns have changed over the past few decades, with an increase in saturated and omega-6 fat consumption, and a reduction in polyunsaturated omega-3 fat intake, this may be an important factor in the increasing prevalence of asthma and possibly other allergic diseases. (ispub.com)
These cells can participate in inflammatory responses by releasing mediators that attract or activate other cells, contributing to the pathogenesis of allergic and non-allergic diseases. (mdpi.com)
The researchers say the combination could be a potentially dangerous food source for some patients with heart disease, arthritis, asthma and other allergic and auto-immune diseases that are particularly vulnerable to an 'exaggerated inflammatory response. (news-medical.net)

Acute allergic inflammation of the lungs. (nih.gov)
Acute local anaphylactic inflammation of the lungs. (nih.gov)
These results indicate that antigen-specific Th1 cells may not protect or prevent Th2-mediated allergic disease, but rather may cause acute lung pathology. (jci.org)
Acute dry coughs may also be due to inhaled irritants or from a blood clot passing into the lungs. (healthy.net)
Allergic Conjunctivitis Allergic conjunctivitis is an acute, intermittent, or chronic conjunctival inflammation usually caused by airborne allergens. (msdmanuals.com)
We provided evidence of interactive outcomes after air pollution constituent co-exposure and identified a key mechanistic pathway that can potentially explain epidemiological observation of lung function decline after an acute peak of air pollution. (cdc.gov)

Lloyd studies the lung cells of children who suffer from asthma and severe wheeze. (wikipedia.org)
Highly specialized biologic medications that target specific types of airway inflammation are available for those with severe disease. (springfieldclinic.com)
Surprisingly, Th1 cells did not attenuate Th2 cell-induced airway hyperreactivity and inflammation in either SCID mice or in OVA-immunized immunocompetent BALB/c mice, but rather caused severe airway inflammation. (jci.org)

Occurs when Aspergillus causes inflammation in the lungs and allergy symptoms such as coughing and wheezing, but doesn't cause an infection. (cdc.gov)
Occurs when Aspergillus causes inflammation in the sinuses and symptoms of a sinus infection (drainage, stuffiness, headache) but doesn't cause an infection. (cdc.gov)
Occurs when Aspergillus infection causes cavities in the lungs, and can be a long-term (3 months or more) condition. (cdc.gov)
Fig. 3: Phagocytosis function of newly formed resident lung alveolar macrophages is altered locally by secondary inflammatory mediators released during infection. (nature.com)
However, if the linings of the sinuses have been breached by infection or irritants in the environment, then the IL-25 can access the underlying tissue, resulting in recruitment of additional immune cells and local inflammation. (sciencedaily.com)
aspergillus infection of the lung. (rbht.nhs.uk)
She is also a principal investigator in the Centre for Respiratory Infection , which is funded by the Wellcome Trust, and the Medical Research Council & Asthma UK Centre for Allergic Mechanisms of Asthma . (rbht.nhs.uk)
Prof. Boyton has specialist clinical expertise in lung infection (including Streptococcus pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa, non-tuberculous mycobacteria (NTM), Aspergillus fumigatus ), bronchiectasis and host immunity to infection. (imperial.ac.uk)
Inflammation from irritants or infection can increase respiratory fluid production and the number of immune defense cells, and leading to excessive sputum production. (healthy.net)
Sputum colored with pus is indicative of a secondary bacterial infection, although a yellowish sputum may be caused by an allergic response. (healthy.net)
10% of patients mainly because of prosthetic joint infection caused by bacteria or aseptic implant loosening caused by chronic inflammation. (cdc.gov)
Within weeks, infection spreads to other tissues and organs, most commonly the kidney, liver, spleen, lung, and brain, depending on the species-specific interaction with the host ( 8 ). (cdc.gov)
10% of those patients because of implant failure caused mainly by prosthetic joint infection and aseptic implant loosening from inflammation ( 13 , 14 ). (cdc.gov)

The prevalence of asthma and allergic sensitization was 4 and 6 times lower in the Amish population, with higher median endotoxin levels in house dust. (medscape.com)

The current authors have previously demonstrated that diesel exhaust particles (DEP) enhance antigen-related airway inflammation in mice. (ersjournals.com)
The current authors investigated the effects of naphthoquinone (NQ), one of the extractable chemical compounds of DEP, on antigen-related airway inflammation, local expression of cytokine proteins, and antigen-specific immunoglobulin (Ig) production in mice. (ersjournals.com)
The current authors have recently demonstrated that extracted organic chemicals from DEP, rather than residual carbonaceous nuclei of DEP after extraction, predominantly enhance antigen-related airway inflammation in mice 17 . (ersjournals.com)
More recently, it has also been demonstrated that PQ aggravates antigen-related airway inflammation in mice, and that PQ also has adjuvant activity for antigen-specific Igs 25 . (ersjournals.com)
Glyphosate differentially affects allergic immune response across generations in mice. (ufz.de)
OVA-TCR transgenic Th cells migrate to the lungs of recipient mice. (jci.org)
Four days after adoptive transfer of OVA-specific Th cell lines (2.5 × 10 6 cells per mouse), mice were sacrificed and lung tissue was embedded in OCT compound. (jci.org)
2016. Dietary Enrichment with 20% Fish Oil Decreases Mucus Production and the Inflammatory Response in Mice with Ovalbumin-Induced Allergic Lung Inflammation. . (oregonstate.edu)
Recent findings show that encountered in the workplace include toluene diisocya- sensitized mice develop airway hyperreactivity and inflammation, nate (TDI), diphenyl-methane diisocyanate and hexam- reflective of human disease. (cdc.gov)
Environmentally/occupationally relevant lung deposition levels in mice were achieved after inhalation of stable aerosols with similar aerodynamic and mass median distributions. (cdc.gov)

New target molecules and mediators as well animal model, diisocyanate, diphenyl-methane diisocyanate, as new therapeutic approaches for allergic asthma have hexamethylene diisocyanate, murine model, occupational been identified using animal models. (cdc.gov)

Fortunately, there are great asthma treatments, including daily preventative inhalers, that target inflammation as well as rescue inhalers that relieve sudden symptoms. (springfieldclinic.com)
There are many botanicals that can help us reduce airway inflammation and thus control asthma symptoms. (mariasfarmcountrykitchen.com)
If anaphylaxis is suspected, sample collection should take place 15 minutes to 3 hours after onset of allergic signs and symptoms. (medscape.com)

One variety, Cordyceps sinensis, has been shown to reduce airway inflammation and hypersensitivity in animals. (mariasfarmcountrykitchen.com)
EPA is a substrate for the generation of less active prostanoids and leukotrienes than arachidonic acid, thereby potentially acting to reduce airway inflammation and bronchoconstriction 7 . (ispub.com)

In addition, cells in the lungs can produce mucus in response to triggers. (healthywomen.org)
This mucus coating is an important defense mechanism, since it collects and moves waste matter and inhaled particles away from the lungs. (healthy.net)

She is part of the Asthma UK Centre in Allergic Mechanisms of Asthma. (wikipedia.org)
Dr Boyton is the postgraduate director for the prestigious four-year Masters/PhD training programme of the Medical Research Council & Asthma UK Centre for Allergic Mechanisms of Asthma. (rbht.nhs.uk)
Prof. Boyton is a Principal Investigator in the MRC & Asthma UK centre in Allergic Mechanisms of Asthma . (imperial.ac.uk)

More recently an experimental clinical study in mild asthma suggests bronchial allergic inflammation is related to a diet deficient in polyunsaturated fatty acids 14 . (ispub.com)
Asthma is a clinical syndrome characterized by episodic reversible airway obstruction, increased bronchial reactivity, and airway inflammation. (medscape.com)

The current authors have recently shown that PQ induces recruitment of inflammatory cells, such as eosinophils and neutrophils, into the lung with the lung expression of pro-inflammatory molecules such as interleukin (IL)-5 and eotaxin in vivo 24 . (ersjournals.com)
Environmental exposure in sensitized individuals induces airway inflammation, a hallmark finding in the asthmatic lung . (medscape.com)
Several studies have demonstrated that IL-17F plays a pivotal role in allergic airway inflammation and induces several asthma-related molecules such as CCL20. (hindawi.com)

Lung function tests assess airflow (spirometry) and airway inflammation (exhaled nitric oxide). (springfieldclinic.com)
Background Fractional exhaled nitric oxide (FeNO) is a marker of type-2 inflammation used both to support diagnosis of asthma and follow up asthma patients. (uib.no)
An elevated measurement of exhaled nitric oxide (called eNO) can indicate lung inflammation. (healthywomen.org)

The group is focused on understanding the role of innate and adaptive immunity in allergic and infectious inflammation in the lung. (rbht.nhs.uk)
Prof. Boyton studies the interplay between pathogen, host microbiota and innate and adaptive immune mechanisms in the regulation of inflammation. (imperial.ac.uk)

Emergency responders may also use intravenous antihistamines or cortisone to decrease inflammation in the air passages. (healthline.com)
These triggers can cause airway obstruction or blockage where the lungs tighten, constricting the air passages and making breathing difficult. (healthywomen.org)

In humans with systemic inflammation, AMs and also circulating monocytes still displayed alterations consistent with reprogramming six months after resolution of inflammation. (nature.com)

These findings have significant implications with regard to current therapeutic goals in asthma and allergy and suggest that conversion of Th2-dominated allergic inflammatory responses into Th1-dominated responses may lead to further problems. (jci.org)

The metabolites produced by them not only modulate gastro-intestinal immunity, but also impact distal organs like lung and brain. (frontiersin.org)
Medicinal mushrooms are known to balance immunity, modulate inflammation, and provide numerous other beneficial effects. (mariasfarmcountrykitchen.com)

Allergic asthma, which is present in as many as 10% of individuals in industrialized nations, is characterized by chronic airway inflammation and hyperreactivity induced by allergen-specific Th2 cells secreting interleukin-4 (IL-4) and IL-5. (jci.org)
Risk factors for asthma include a family history of allergic disease, the presence of allergen-specific immunoglobulin E (IgE), viral respiratory illnesses , exposure to aeroallergens , cigarette smoke, obesity , and lower socioeconomic status. (medscape.com)

Mechanistic and therapeutic approaches to occupational exposure-associated allergic and non-allergic asthmatic disease. (cdc.gov)

She investigates allergic immunity in early life. (wikipedia.org)

Maternal phthalate exposure promotes allergic airway inflammation over two generations via epigenetic modifications. (ufz.de)

Invasive aspergillosis most commonly affects the lungs, but it can also spread to other parts of the body. (cdc.gov)

Occurs when a ball of Aspergillus grows in the lungs or sinuses, but usually does not spread to other parts of the body. (cdc.gov)

Galectin-3 is an inflammatory protein associated with cancer, heart disease, and other conditions related to inflammation and fibrosis. (mariasfarmcountrykitchen.com)

She was then awarded an MRC Clinician Scientist Fellowship to develop inducible, lung-targeted models of lung inflammation. (rbht.nhs.uk)

DEP enhance the antigen-specific immunoglobulin (Ig)E response 5 , 6 and aggravate airway inflammation induced by repetitive intratracheal instillation of antigen in vivo 7 - 10 . (ersjournals.com)

While surveillance, systems engineering, and exposure mitigation strategies are essential preventative considerations, no targeted medical therapies are currently available to ameliorate lung injury post-exposure and prevent chronic airway disease development. (cdc.gov)
Summary: The course of occupational lung disease that follows exposure is informed by individual predisposition, immunobiologic response, agent identity, overall environmental risk, and preventative workplace practices. (cdc.gov)
The aim of the present study was to elucidate the effects of NQ on airway inflammation, the local expression of cytokines such as IL-4 and IL-5 and chemokines such as eotaxin, macrophage chemoattractant protein (MCP)-1, and keratinocyte chemoattractant (KC) and Ig production related to antigen exposure. (ersjournals.com)
Compared with individual exposures, co-exposure aerosols produced greater acellular and cellular oxidants detected by electron paramagnetic resonance (EPR) spectroscopy, and in vivo immune-spin trapping (IST), as well as synergistically increased lavage neutrophils, lavage proteins and inflammation related gene/protein expression. (cdc.gov)

The results from these studies have the transformative potential to influence approaches to improve lung function and asthma-associated anxiety/depression. (centerwatch.com)

Allergen-induced respiratory inflammation facilitates and/or elicits the extravasation of proinflammatory leukocytes by well-understood mechanisms that mediate the movement of multiple cell types. (elsevierpure.com)
CX 3 CR 1 + Macrophage Facilitates the Resolution of Allergic Lung Inflammation via Interacting CCL26. (bvsalud.org)

Lung section stained with biotinylated control antibody plus Streptavidin-FITC. (jci.org)

Of particular importance is identifying allergic triggers. (springfieldclinic.com)

The herbs are known to decrease inflammation in the lungs and hence clearing out the air passage ways for better breathing. (planetayurveda.com)

IL-17F is expressed in activated CD4 + T cells, basophils, and mast cells, three important cell types involved in allergic airway inflammation [ 3 ]. (hindawi.com)

Dysbiosis within this homeostasis in the gut microbiota is associated with a multitude of health conditions affecting not only gut, but also distal organs like mouth, lung, brain, liver, vagina, etc. (frontiersin.org)

Additional mechanistic studies further suggested that the ability of circulating cancer cells to extravasate to surrounding lung tissues was linked to the activation of the vascular endothelium via one or more Gα i -coupled receptors. (elsevierpure.com)

Her research group, the Lloyd Lab, look at the interactions between lung cells and infiltrating inflammatory cells. (wikipedia.org)

Prenatal and postnatal environment exposures may disturb lung growth and delay immune system maturation, resulting in an increased susceptibility to asthma and wheezing disorders in childhood. (bvsalud.org)

You probably know someone who is severely allergic to something, like peanuts or bee stings. (healthline.com)
When the lungs react severely to a trigger, what's known as an 'asthma attack' may occur. (healthywomen.org)

Recent Findings: This article reviews contemporary understanding of allergic and non-allergic occupational asthma mechanisms. (cdc.gov)

Title : Surface area- and mass-based comparison of fine and ultrafine nickel oxide lung toxicity and augmentation of allergic response in an ovalbumin asthma model Personal Author(s) : Roach, Katherine A.;Anderson, Stacey E.;Stefaniak, Aleksandr B.;Shane, Hillary L.;Kodali, Vamsi;Kashon, Michael;Roberts, Jenny R. (cdc.gov)

Apart from intestinal disorders (diabetes, obesity, colon cancer, inflammatory bowel disease, etc.), changes in dietary patterns and their effects on gut microbiota are implicated in disorders of other organs like lung (asthma, COPD, etc. (frontiersin.org)
Dr. Ewbank and Dr. Smart specialize in all aspects of allergic disease and asthma. (springfieldclinic.com)

IL-17F-induced CCL20 may attract Th17 cells into the airway resulting in the recruitment of additional Th17 cells to enhance allergic airway inflammation. (hindawi.com)

Anatomy31

Organisms15

Diseases57

Chemicals and Drugs94

Analytical, Diagnostic and Therapeutic Techniques and Equipment29

Psychiatry and Psychology1

Phenomena and Processes29

Disciplines and Occupations1

Technology, Industry, Agriculture2

Health Care3

Pulmonary8

Reaction16

Immunology4

Airways8

Rhinitis6

Reactions8

Diseases9

Acute6

Severe3

Infection13

Sensitization1

Mice10

Murine1

Symptoms3

Reduce airway inflammation2

Mucus2

Asthma UK Centre3

Bronchial2

Induces3

Nitric oxide3

Innate and adaptive2

Passages2

Systemic1

Allergy1

Modulate2

Allergen-specific2

Asthmatic1

Immunity1

Promotes1

Commonly1

Sinuses1

Fibrosis1

Inducible1

Antigen-specific1

Exposure4

Approaches1

Facilitates2

Antibody1

Triggers1

Decrease1

Mast cells1

Liver1

Tissues1

Inflammatory cells1

Susceptibility1

Severely2

Occupational1

Ultrafine1

Disease2

Recruitment1