• A wild type allele is an allele which is considered to be "normal" for the organism in question, as opposed to a mutant allele which is usually a relatively new modification. (bionity.com)
  • Absolute quantities of plasma EGFR mutant and wild-type alleles were measured by ddPCR. (mendeley.com)
  • The reason I'm focusing on alleles with selective value is that moments like the settlement of the Americas by a small group of Iberian men and the generation of a mestizo population within a century through hybridization are rare events. (gnxp.com)
  • When Richard Lewontin and J. Hubby published their groundbreaking results in 1966 which showed high levels of genetic variation in Drosophila via protein electrophoresis, the theoretical results from the infinite alleles model were used by Kimura and others to support the idea that this variation would have to be neutral (or result in excess segregational load). (wikipedia.org)
  • For example, allele frequency tables are often presented for genetic markers, such as the DYS markers. (bionity.com)
  • where p is the frequency of one allele and q is the frequency of the other allele. (bionity.com)
  • Natural selection can act on p and q in Equation 1, and obviously affect the frequency of alleles seen in Equation 2. (bionity.com)
  • For some genetic diseases, especially those that have low penetrance or are easily treatable, carrier screening may be of questionable value when pseudodeficiency alleles are present at high frequency. (wikipedia.org)
  • The ABO system in humans is controlled by three alleles, usually referred to as I A , I B , and I O (the "I" stands for isohaemagglutinin). (encyclopedia.com)
  • These results became important in the formation of the neutral theory, because neutral (or nearly neutral) alleles create no such segregational load, and allow for the accumulation of a great deal of polymorphism. (wikipedia.org)
  • List of alleles describe known sequence alternatives in a variable region. (cpan.org)
  • In addition describing the allele by its sequence , it possible to give describe repeat structure within the sequence. (cpan.org)
  • Allele objects that have zero length sequence string. (cpan.org)
  • Function: Sets and returns the sequence of the repeat_unit the allele is composed of. (cpan.org)
  • There can be several variations of this sequence, and each of these is called an allele. (dictionary.com)
  • A pseudodeficiency allele may indicate a deficiency of the enzyme assay method, or it may reflect incomplete understanding of the enzyme's activity. (wikipedia.org)
  • Also there are many different types of alleles. (bionity.com)
  • The archive will collect semen from 20 rams of each breed, with 400 semen doses representing each susceptible allele from 11 main breeds and 100 semen doses of each allele for every other breed. (fwi.co.uk)