Peptides with strong bioactivity potential from aldehyde dehydrogenase, lactoylglutathione lyase, SEC14-like protein 3 and others were identified. (bvsalud.org)
The systematic name of this enzyme class is (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase (pyruvate-forming). (wikipedia.org)
Previous studies have revealed the presence of eutBC genes encoding ethanolamine-ammonia lyase, a key enzyme that breaks ethanolamine into acetaldehyde and ammonia, in about 100 bacterial genomes including members of gamma-proteobacteria. (beds.ac.uk)
Functionally, mutant kind of S1P lyase deleted in C-terminal 21 amino acids showed decreased enzyme activities as well as significantly less inhibitory impact on release of the AEVs when compared with wild kind. (squalene-epoxidase.com)
TPP is required by this component of the peroxisomal enzyme complex involved in fatty acid catabolism.41 This enzyme catalyzes the TPP-dependent cleavage of 2-hydroxy fatty acids (e.g., 2-hydroxyoctadecanoic acid42) to yield formate and a 1C-shortened aldehyde. (ferienwohnung-gluecksburg.net)
Sphingosine phosphate lyase1
sphingosine phosphate lyase (Sgpl1), and paraoxonase 1 (Pon1). (nih.gov)
Aldolase1
Other names in common use include 2'-carboxybenzalpyruvate aldolase, (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate, 2-carboxybenzaldehyde-lyase, and (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase. (wikipedia.org)
Enzymes3
Au sein de celle-ci, les actions combinées de trois enzymes, lipase, lipoxygénase (LOX) et hydroperoxyde lyase (HPL), convertissent un substrat lipidique (acides C 18:2 et C 18:3 ) en molécules volatiles à courte chaine. (ac.be)
Combined actions of three enzymes: lipase, lipoxygenase (LOX) and hydroperoxide lyase (HPL) convert lipidic substrates such as C 18:2 and C 18:3 fatty acids into short chain volatiles. (ac.be)
ALDH is a family of detoxifying enzymes responsible for the oxidation of intracellular aldehydes whose activity was initially found to be increased in hematopoietic and neural stem and progenitor cells. (xcessbio.com)
This adaptation is validated by comparing PROPKA 2.0 predictions to experimental data for 26 protein-ligand complexes including trypsin, thrombin, three pepsins, HIV-1 protease, chymotrypsin, xylanase, hydroxynitrile lyase, and dihydrofolate reductase. (nih.gov)
Bhunya R, Mahapatra T, Nanda S. ( 2009 ) Prunus armeniaca hydroxynitrile lyase (ParsHNL)-catalyzed asymmetric synthesis of cyanohydrins from sterically demanding aromatic aldehydes Tetrahedron: Asymmetry . (academictree.org)
Fatty4
GLVs are metabolized from C 18 -polyunsaturated fatty acids (including linoleic and linolenic acids) producing C 6 - and C 9 -aldehydes (Matsui et al. (ac.be)
The cleavage of sphingoid base phosphates by sphingosine-1-phosphate (S1P) lyase to produce phosphoethanolamine and a fatty aldehyde is the final degradative step in the sphingolipid metabolic pathway. (nih.gov)
As is well-known, S1P is synthesized from sphingosine by sphingosine kinase 1/ 2-mediated phosphorylation and irreversibly degraded into fatty aldehydes and phosphoethanolamine by theIntroduction: The nanoparticles referred as exosomes play an active role in intercellular communication. (squalene-epoxidase.com)
There was evidence tiiat oxidative changes in polyunsaturated fatty acids in debris led to water-soluble toxic aldehydes tiiat were detectable in the viti:eous and toxic to lens ceUs and membranes. (nih.gov)
Sgpl11
Recently recessive mutations in sphingosine-1-phosphate lyase (SGPL1) have been published as a cause of syndromic congenital nephrotic syndrome with adrenal insufficiency. (nih.gov)
KETONES1
A molecule containing a hydroxyl group and a carbonyl group is cleaved at a C-C bond to produce two smaller molecules ( ALDEHYDES or KETONES ). (nih.gov)
Degradation5
Having said that, S1P lyase was not a direct target of caspases for the reason that mutations of Asp residues at C-terminal regions didn't block its degradation. (squalene-epoxidase.com)
Possibly, S1P lyase might be a substrate of calpain in that co-treatment of a calpain inhibitor, PD150606 with staurosporine inhibited the degradation of S1P lyase. (squalene-epoxidase.com)
In constant with this, knock-down of an endogenous inhibitor of calpain, calpastatin elevated the degradation of S1P lyase while knock-down of calpain smaller subunit, CAPNS1 decreased the degradation of S1P lyase. (squalene-epoxidase.com)
Summary/Conclusion: C-terminal degradation of S1P lyase for the duration of apoptotic processes contribute to enhancement of biogenesis of your AEVs, possibly by means of decreasing enzymatic activities of S1P lyase and subsequent increment of S1P in ER region. (squalene-epoxidase.com)
While degradation of S1P lyase is caspases-dependent, S1P just isn't a direct substrate of caspases. (squalene-epoxidase.com)
Aliphatic1
In this thesis, conventional and unconventional reaction media were used for the synthesis of symmetric, aliphatic, vicinal diols from biobased aldehydes. (rwth-aachen.de)
Acetaldehyde1
While ammonia serves as a cellular source of reduced nitrogen, the acetaldehyde is further converted to acetyl-CoA, by an aldehyde oxidoreductase encoded by eutE, and enters the carbon pool of the cell. (beds.ac.uk)
Over-expression of N-terminal 3X flag- and C-terminal HA-tagged S1P lyase turned out that C-terminal area of S1P lyase was degraded. (squalene-epoxidase.com)
These reactions, triggered by cell membrane disruptions, produce compounds known as Green Leaf Volatiles (GLVs) which are C 6 or C 9 -aldehydes and alcohols. (ac.be)
Final1
Final results: S1P lyase was degraded caspases-dependently in HeLa cells by apoptotic stimuli. (squalene-epoxidase.com)
Major1
This graph shows the total number of publications written about "Carboxy-Lyases" by people in this website by year, and whether "Carboxy-Lyases" was a major or minor topic of these publications. (uchicago.edu)
Note1
Ces réactions stimulées par l'endommagement des cellules membranaires produisent des composés communément appelés Molécules à Note Verte (MNV) dénominant des aldéhydes et des alcools en C 6 ou en C 9 . (ac.be)