Albicans pathogenic. Medical search. Frequent questions

At Montana Western, Dr. Morrow and his undergraduate student researchers are studying some of the proteins that play roles in the early secretory pathway of the pathogenic yeast Candida albicans. (umwestern.edu)
The Sec61 protein plays a role in the translocation of secretory proteins across the endoplasmic reticulum membrane in the pathogenic yeast Candida albicans. (umwestern.edu)
Can the pathogenic yeast Candida albicans live without the SEC63 gene? (umwestern.edu)

To broaden our understanding on the population structure and genetic diversity of C. albicans strains in birds, we analysed 30 isolates recovered from animal and human hosts and investigated whether the genotype distribution related to their different source. (springer.com)
In vitro broth micro-dilution methods were used to evaluate activity against human pathogenic Gram (+) and Gram (-) bacterial strains and Candida albicans. (usda.gov)
Three C. albicans strains, two isolated from the oral cavities of HIV positive patients and an ATCC 90028 strain, were used in the study. (hindawi.com)
The use of denture is known to increase the carriage of Candida in healthy patients, and the proliferation of Candida albicans strains can be associated with denture-induced stomatitis. (scielo.br)
Individual Candida albicans yeast strains in the human gut are as different from each other as the humans who carry them, and some C. albicans strains may damage the gut of patients with inflammatory bowel disease (IBD), according to a new study from researchers at Weill Cornell Medicine. (scienceblog.com)
treating mice with the drug to suppress intestinal inflammation failed in the presence of high-damaging C. albicans strains. (scienceblog.com)
Our findings suggest that C. albicans strains do not cause spontaneous intestinal inflammation in a host with intact immunity," Iliev said. (scienceblog.com)
Our finding shows that a cell-damaging toxin candidalysin released by "high damaging" C. albicans strains during the yeast-hyphae morphogenesis triggers pathogenic immunological responses in the gut," said the first author Xin Li, who was a Charles H. Revson Postdoctoral Fellow in the Iliev laboratory at the time of the study. (scienceblog.com)
PT-1 strongly inhibits pathogenic microbial strains, including Candida albicans, Rhizoctonia solani, and Clavibacter michiganense subsp. (copewithcytokines.org)
A study from the lab of Teresa O'Meara, Ph.D. of the U-M Medical School Department of Microbiology and Immunology finds that the colonizing strains are very similar to pathogenic strains. (umich.edu)
The new study has suggested one reason steroids, a commonly used treatment, may not work: Treating mice with the drug to suppress intestinal inflammation failed in the presence of "high-damaging" C. albicans strains. (medicalxpress.com)
In this study, three probiotic Lactobacilli strains ( Lactobacillus plantarum 8014, L. plantarum 14917, and Lactobacillus salivarius 11741) were tested on S. mutans and C. albicans clinical isolates using a multispecies biofilm model simulating clinical cariogenic conditions. (bvsalud.org)

The commensal yeast C. albicans is one of the main causes of nosocomial fungal infectious diseases, whereas the filamentous fungus A. fumigatus has become one of the most prevalent airborne fungal pathogens. (leibniz-hki.de)
The fungus Candida albicans, a type of yeast, lives in the gut microbiota and plays a role in health and gastrointestinal disease. (eurekalert.org)
Candida albicans is another common fungus that causes skin infections and it most commonly affects the vaginal and groin areas. (naturalnews.com)
Candida albicans is a fungus of great medical and veterinary importance to be pathogenic to humans and other warm-blooded animals, accounting for 80-90% of fungal infections. (usp.br)
Candida albicans is an opportunistic fungus, which requires some predisposing factors for the disease development, such as immunosuppressive agents, use of broad-spectrum antibiotics, xerostomia, prosthetic use and poor oral hygiene. (bvsalud.org)
[ 1 ] C albicans is a dimorphic fungus that can asymptomatically colonize the gastrointestinal and genitourinary tracts (and their associated mucosae) in healthy individuals. (medscape.com)
A unicellular budding fungus which is the principal pathogenic species causing CANDIDIASIS (moniliasis). (bvsalud.org)

Most of these commensal C. albicans cells proliferate as budding yeasts. (hindawi.com)
Potential anti-infective targets in pathogenic yeasts: Structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans. (mpg.de)
Clotrimazole is a broad-spectrum antifungal agent that inhibits the growth of pathogenic yeasts by altering the permeability of cell membranes. (nih.gov)
Potentially pathogenic fungi include yeasts (single-celled organisms, eg, Candida albicans ) and dermatophytes. (msdmanuals.com)
VVC usually is caused by Candida albicans but can occasionally be caused by other Candida species or yeasts. (cdc.gov)
Yeast culture, which can identify a broad group of pathogenic yeasts, remains the reference standard for diagnosis. (cdc.gov)

The most common pathogenic species are Aspergillus fumigatus and Aspergillus flavus. (wikipedia.org)
Certain species may become pathogenic, especially C. albicans, which causes thrush and other infections. (dictionary.com)
Candida albicans is one of the most formidable fungal species, causing infection in humans. (pasteur.fr)
Although the genus Candida consists of around 200 species, only 20 are reported as etiological agents of IC, being Candida albicans the most frequent causal agent. (intechopen.com)
Candida albicans is the most common species of yeast isolated from patients with oral candidiasis [ 2 ]. (hindawi.com)
Candida albicans was the species most often isolated. (who.int)
Infection of the skin or mucous membrane with any species of candida, usually Candida albicans . (diagnose-me.com)
Since pathogenic yeast species such as Candida albicans use a corresponding protein region to bind human endothelial and epithelial cells, the information provided by these findings could also be relevant for infection medicine," says Luca Jovine. (sciencedaily.com)
The action of clotrimazole is fungistatic at concentrations of drug up to 20 mcg/mL and may be fungicidal in vitro against Candida albicans and other species of the genus Candida at higher concentrations. (nih.gov)
On the negative side there are many fungal species that cause plant diseases and pose a high threat by crop loss, however some members of this fungal family also act as biocontrol agents in preventing the pathogenic members. (databasefootball.com)
Infection is caused by Candida species, primarily Candida albicans . (medscape.com)

The virulence factors of Candida albicans are germ tube and biofilm formation, adherence to host tissues, and production of hydrolytic enzymes. (hindawi.com)

Both fungi Candida albicans and Aspergillus fumigatus can cause a number of life-threatening systemic infections in humans. (leibniz-hki.de)
The pathogenic fungi Candida albicans and Candida glabrata are obligate human commensals that can cause disease when host immune systems are compromised. (findaphd.com)

Streptococcus mutans and Candida albicans are well-known emerging pathogenic bacteria / fungi for dental caries . (bvsalud.org)
we collected swabs of vaginal discharge for the detection of pathogenic bacteria. (bvsalud.org)

The opportunistic human fungal pathogen Candida albicans relies on cell morphological transitions to develop biofilm and invade the host. (lu.se)
C. albicans is an opportunistic pathogen in humans. (wikipedia.org)
Candida albicans, which is a normal inhabitant in the throat, mouth, genitourinary tract and intestine, is an opportunistic type of yeast. (naturalnews.com)
Candida albicans is an opportunistic fungal pathogen that is the principal cause of superficial and systemic candidiasis in human and animals. (scialert.net)
Opportunistic 'high-damaging' Candida albicans strain in the colon mucosa of IBD patient secretes the toxin candidalysin (red dots) during the transition from a benign commensal to a pathogenic state and aggravates intestinal inflammation. (medicalxpress.com)

Although fungi are eukaryotic, many pathogenic fungi are microorganisms. (wikipedia.org)
Other human pathogenic microorganisms were also inhibited within a moderate range (MIC = 125-1000 µg/mL). (usda.gov)
Probiotics interfere with pathogenic microorganisms or reinstate the natural microbiome . (bvsalud.org)

In this study, multilocus sequence typing was used to characterise the genetic diversity and population structure of 24 avian origin C. albicans isolates collected from different birds with candidiasis and compared to human isolates. (springer.com)
Primary infection with C. albicans occurs from acquisition of maternal flora in the perinatal period and is followed by a state of colonization, which evolves into a state of commensalism, except in rare cases of neonatal candidiasis ( 2 ). (rupress.org)
Mouse models of candidiasis, including models of OPC, vaginitis, and disseminated disease, have been invaluable in advancing our understanding of the immune response to C. albicans . (rupress.org)
C albicans is the predominant causal organism of most candidiasis. (medscape.com)

Pathogenic fungi are fungi that cause disease in humans or other organisms. (wikipedia.org)
however, the relationship between in vitro susceptibility of pathogenic fungi to clotrimazole and prophylaxis or cure of infections in humans has not been established. (nih.gov)
However, because the relationship between humans and C. albicans is unique, animal models do not fully recapitulate the human disease. (rupress.org)

Candida albicans can form biofilms that exhibit elevated intrinsic resistance to various antifungal agents, in particular azoles and polyenes. (who.int)

We observed that IAA also induced hyphal growth in the human pathogen Candida albicans and thus may function as a secondary metabolite signal that regulates virulence traits such as hyphal transition in pathogenic fungi. (nih.gov)

Important interpretation is provided about the hyphal form of C. albicans , which clarifies the germ tube's role in morphogenesis and, potentially, in disease. (cdc.gov)
Hyphal growth during infection is arguably a pathogenic factor since it thwarts phagocytosis. (cdc.gov)
These govern multiple functions, including hyphal development and the secretion of pathogenic factors. (cdc.gov)
The scanning electron micrograph shows the yeast in its pathogenic, hyphal form. (eurekalert.org)
The ability to switch between yeast and hyphal morphologies can play a role in the virulence of C. albicans [ 4 ]. (hindawi.com)

An agent that kills or inhibits fungi, or a compound that inhibits either a dermatomycosis like ringworm or athlete's foot, or one that inhibits Candida albicans either externally as a douche or internally as a systemic antifungal. (diagnose-me.com)

These results suggested that the resistance of C. albicans biofilms to azoles or polyenes was due not to the activation of specific mechanisms in response to exposure to these antifungals but rather to the intrinsic properties of the mature biofilms. (who.int)

Our study findings show a remarkable inhibitory effect of L. plantarum 14917 on S. mutans and C. albicans clinical isolates, resulting in significantly reduced growth of S. mutans and C. albicans, a compromised biofilm structure with a significantly smaller microbial and extracellular matrix and a less virulent microcolony structure. (bvsalud.org)

However, Saccharomyces boulardii is a wonderful yeast that helps control pathogenic yeast and promotes overall health. (red23.co.uk)

Due to elevated levels of blood sugar in diabetes, Candida albicans may shift from yeast to an invading mycelial fungal form. (naturalnews.com)
Biotin has also been shown to be able to prevent yeast, such as Candida albicans , from converting to the more pathogenic fungal form. (diagnose-me.com)

Animax is also indicated in the management of dermatologic disorders characterized by inflammation and dry or exudative dermatitis, particularly those caused, complicated, or threatened by bacterial or candidal (Candida albicans) infections. (medi-vet.com)

Nystatin is the first well-tolerated antifungal antibiotic of dependable efficacy for the treatment of cutaneous infections caused by Candida albicans (Monilia). (medi-vet.com)

To evaluate the effect of photodynamic therapy in the inactivation of Candida albicans planktonic cells, using methylene blue, 150 mg/mL, as a photosensitizer. (bvsalud.org)
Mature C. albicans biofilms grown under continuous flow were exposed for as long as 2 h to concentrations of fluconazole (FLU), amphotericin B (AMB), and caspofungin (CAS) that, while lethal for planktonic cells, were not lethal for biofilms. (who.int)
There was little overlap between AMB- or CAS-responsive genes in biofilms and those that have been identified as AMB, FLU, or CAS responsive in C. albicans planktonic cultures. (who.int)

Several molecular mechanisms with antifungal agents have been reported for C. albicans where insertions, deletions, and point mutations in genes codifying target proteins are frequently related to the antifungal drug resistance. (intechopen.com)
This chapter summarizes the main molecular mechanisms to C. albicans antifungal drug resistance, besides offering an overview of new antifungal agents and new antifungal targets to combat fungal infections. (intechopen.com)
We have used transcript profiling to explore the early transcriptional responses of mature C. albicans biofilms exposed to various antifungal agents. (who.int)

Certain conditions favor pathogenic overgrowth of Candida. (vin.com)

The mechanistic assessment indicated that L. plantarum 14917 had a positive inhibitory impact on the expression of S. mutans and C. albicans virulence genes and virulent structure, such as C. albicans hypha formation. (bvsalud.org)

The molecular genetics of morphogenesis in C. albicans follows. (cdc.gov)

Candida albicans is a kind of diploid yeast that commonly occurs among the human gut microflora. (wikipedia.org)
C. albicans is predominantly diploid and displays high degree of genetic diversity across isolates, notably variations in the distribution of heterozygous polymorphisms along the genome. (springer.com)

C. albicans cells bearing germ tubes are more adherent to buccal epithelial cells (BEC) than yeast forms of C. albicans [ 5 ] due to the antigens found on germ tubes [ 6 ]. (hindawi.com)

Candida albicans, C. tropicalis, C. glabrata, C. parapsilosis and C. guilhermondii were seeded into antibacterial (cefepime, meropenem, vancomycin, and piperacillin- tazobactam) gradient plates produced in Mueller-Hinton Agar. (bvsalud.org)

According to the World Health Organization (WHO) in 2022 pathogens of particular concern are: Critical priority Cryptococcus neoformans, Candida auris, Aspergillus fumigatus, Candida albicans. (wikipedia.org)
Identification of virulence determinants of the human pathogenic fungi Aspergillus fumigatus and Candida albicans by proteomics. (leibniz-hki.de)
Kniemeyer O, Schmidt AD, Vödisch M, Wartenberg D, Brakhage AA (2011) Identification of virulence determinants of the human pathogenic fungi Aspergillus fumigatus and Candida albicans by proteomics. (leibniz-hki.de)

Here, we review the recent proteome data generated for A. fumigatus and C. albicans that are related to factors required for pathogenicity. (leibniz-hki.de)

Human isolates were randomly selected and preliminary identified as C. albicans by Matrix-assisted laser desorption/ionization time of flight mass spectrometer at the University of Debrecen. (springer.com)
The aim of the study was to evaluate the protein similarity degree among 15 C. albicans isolates with different virulence obtained from healthy and infected human and animals. (scialert.net)
In this study, we described the use of SDS-PAGE, along with PAGE techniques, to analyze the similarity of the protein profiles of the cytoplasmic extracts and cell walls of different C. albicans isolates obtained from different host conditions (human against animal isolates and patient against healthy subject isolates) with various virulence degrees. (scialert.net)
Seventeen fresh C. albicans , originated from infected human (7 isolates) and animals (10 isolates), were obtained from Fungal Collection of Mycology Research Center, University of Tehran between April and November, 2007. (scialert.net)
Candida albicans is unique among major pathogenic fungi in that it is intimately associated with human hosts ( 1 ). (rupress.org)

The completion of both the A. fumigatus and C. albicans genome sequence provides the opportunity to improve diagnosis, to define new drug targets, to understand the functions of many uncharacterised proteins, and to study protein regulation on a global scale. (leibniz-hki.de)
With the application of proteomic tools, particularly two-dimensional gel electrophoresis and LC/MS-based methods, a comprehensive overview about the proteins of A. fumigatus and C. albicans present or induced during environmental changes and stress conditions has been obtained in the past 5 years. (leibniz-hki.de)
2011). The Candida albicans Kar2 protein is essential and functions during the translocation of proteins into the endoplasmic reticulum. (umwestern.edu)
2005). Different types of electrophoretic techniques have been used for the characterization or typing of C. albicans isolates including separation of chromosomes, DNA fragments, isoenzymes, cell wall glycoproteins and whole cell proteins (Asakura et al . (scialert.net)

A total of 30 C. albicans isolates (one isolate from each bird) were examined in this study. (springer.com)
Effect of Probiotic Lactobacillus plantarum on Streptococcus mutans and Candida albicans Clinical Isolates from Children with Early Childhood Caries. (bvsalud.org)
The ten pairs of clinical isolates of S. mutans and C. albicans were obtained from children with severe early childhood caries. (bvsalud.org)

Characterization of the Candida albicans Sec63 Protein. (umwestern.edu)

A further chapter discusses how surface membrane G-protein receptors in C. albicans and other fungi transmit external stimuli through 2 major protein kinase cascades. (cdc.gov)
The whole-cell protein profile obtained by these techniques could provide additional criteria for the serologic and immunologic studies of C. albicans . (scialert.net)

These compounds, benzyl α-l-fucopyranoside and benzyl β-d-xylopyranoside, inhibit the hyphae formation and adhesion of C. albicans to a polystyrene surface, resulting in a reduced biofilm formation. (lu.se)
angustifolia extract on the germ tube and biofilm formation of C. albicans . (hindawi.com)
DVA extract has ability to reduce virulence of C. albicans by inhibiting germ tube and biofilm formation through damage to the cell wall. (hindawi.com)
Pathogenic characteristics such as germ tube and biofilm formation and production of tissue damaging enzymes are possible targets of new drugs. (hindawi.com)
The present study investigated the effect of subinhibitory concentration of crude extract of DVA on the germ tube and biofilm formation by C. albicans . (hindawi.com)

Nystatin is fungistatic in vitro against a variety of yeast and yeast-like fungi including many fungi pathogenic to animals. (medi-vet.com)

The fungal cell cyle is considered with respect to the mechanism of sequential gene expression in Candida albicans, since little is known about the cell cycle in pathogenic molds. (cdc.gov)

For use when taking a pathogenic specific approach to disinfection. (britesources.com)

These facts determined the present study, which aimed to evaluate the effects of gamma radiation (60Co) in yeast and chlamydospores of C. albicans with 320 and 10240 Gy doses. (usp.br)

Because the microorganism remains the same, and the presence of C. albicans in tissues of immunocompetent individuals with intact mucosal surfaces and microbiota is not usually associated with inflammation or damage, the transition between commensalism and disease is almost certainly caused by the immune response. (rupress.org)

Another area of interest is the study of pathogenic mechanisms of Francisella tularensis , a potential bioweapon, with particular interest in determining how this bacterium evades killing within host macrophages. (utsa.edu)

In the current study, we developed new regulatory molecules, which inhibit the morphological transition of C. albicans from yeast-form cells to cells forming hyphae. (lu.se)

Photodynamic Therapy presented antifungal effect against Candida albicans and can be used as an adjunct to conventional treatment. (bvsalud.org)

A novel approach to therapy has been suggested by some researchers, where the virulence of C. albicans can be targeted instead of an antimicrobial property. (hindawi.com)
FurTre, plantaricin, an antimicrobial peptide produced by L. plantarum, inhibited the growth of S. mutans and C. albicans. (bvsalud.org)

Anatomy25

Organisms23

Diseases26

Chemicals and Drugs105

Analytical, Diagnostic and Therapeutic Techniques and Equipment27

Phenomena and Processes50

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture6

Information Science4

Health Care3

Yeast candida albicans3

Strains12

Fungus7

Yeasts6

Species11

Virulence Factors1

Fungi Candida albicans2

Bacteria2

Opportunistic5

Microorganisms3

Candidiasis4

Humans3

Form biofilms1

Pathogen1

Hyphal5

Inhibits1

Antifungals1

Microbial1

Saccharomyces1

Fungal form2

Bacterial1

Monilia1

Planktonic3

Antifungal agents3

Overgrowth1

Genes1

Morphogenesis1

Diploid2

Antigens1

Glabrata1

Aspergillus3

Pathogenicity1

Human5

Proteins4

Isolates3

Characterization1

Protein2

Biofilm formation5

Vitro1

Molds1

Disinfection1

Evaluate1

Tissues1

Mechanisms1

Transition1

Photodynamic1

Antimicrobial2