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  • enzyme
  • It is a reduced nicotinamide-adenine dinucleotide phosphate ( NADPH )-dependent enzyme catalyzing the reduction of various aldehydes and ketones to the corresponding alcohol . (wikipedia.org)
  • Citrate is an uncompetitive inhibitor in the forward reaction with respect to aldehyde (reduction of aldehyde), while it is a competitive inhibitor with respect to alcohol in the backward reaction (oxidation of alcohol), indicating that it interacts with the enzyme-NADP(+)-product complex. (rcsb.org)
  • protein
  • These aldehydes are toxic, at least in part, due to their ability to react with cellular and tissue proteins leading to the formation of advanced lipoxidation end products (ALEs) which induce protein dysfunction and alter cellular responses. (arvojournals.org)
  • amino
  • AKR1B1 consists of 316 amino acid residues and weighs 35853Da. (wikipedia.org)
  • AKR1B1 Human Recombinant amino produced in E.Coli is a single, non-glycosylated polypeptide chain containing 316 amino acids having a molecular mass of 35.8 kDa.The AKR1B1 is purified by proprietary technologyary technonlogyary chromatographic techniques. (promab.com)
  • forms
  • These are hydrogenated forms of carbohydrate in which the carbonyl group (aldehyde or ketone, reducing sugar) has been reduced to a primary or secondary hydroxyl group. (hmdb.ca)