• Go to Obstructive Sleep Apnea (OSA) , Childhood Sleep Apnea , Surgical Approach to Snoring and Obstructive Sleep Apnea , Obstructive Sleep Apnea and Home Sleep Monitoring , Oral Appliances in Snoring and Obstructive Sleep Apnea , Upper Airway Evaluation in Snoring and Obstructive Sleep Apnea , and Sleep-Disordered Breathing and CPAP for more information of these topics. (medscape.com)
  • Nevertheless, the poor tolerance and long-term adherence to Continuous Positive Airway Pressure (CPAP) treatment in OSA ( Weaver and Grunstein, 2008 ), make discovery of such therapeutic alternatives clinically relevant and important. (frontiersin.org)
  • The vast majority of diagnosed patients are prescribed positive air pressure therapy devices such as continuous positive airway pressure, or CPAP, but many patients are dissatisfied with these mechanical nighttime devices and fewer than half are compliant long term, leaving a significant population untreated, undertreated and at risk. (biospace.com)
  • The current treatment of OSA is the continuous positive airway pressure (CPAP) device, a simple yet very efficient modality, but unfortunately also uncomfortable, resulting in poor adherence. (ersjournals.com)
  • However, 0.5-1% of men and 0.1-0.2% of women are candidates for treatment with nasal continuous positive airways pressure (CPAP) to splint open the upper airway during sleep. (nursingjobsexam.com)
  • It will be the first clinically proven medical device approved by the U.S. Food and Drug Administration for use when a CPAP (continuous positive airway pressure) machine would not be prescribed. (bcbusiness.ca)
  • Continuous positive airway pressure (CPAP) is the standard treatment for moderate to severe OSAS.8 Continuous positive pressure acts as a pneumatic splint that prevents the upper airway to collapse. (docksci.com)
  • Obtaining a thorough history and physical examination helps to determine a presumptive diagnosis of OSA, and polysomnography can confirm the diagnosis and severity of OSA and can determine the need for and level of continuous positive airway pressure (CPAP). (clinicalgate.com)
  • It consists of two components - an optogenetic component that makes the upper airway muscles sensitive to light, and a smart oral appliance that senses respiration and delivers light stimuli to activate the upper airway dilator muscles and maintain upper airway patency during sleep. (edu.au)
  • Upper airways patency decreases during sleep due to loss of dilator muscle activity in the pharynx. (nursingjobsexam.com)
  • Obstruction results from high negative pressure generated by the inspiratory effort and failure of the dilating upper airway muscles to maintain airway patency. (medscape.com)
  • violation of patency of the upper respiratory tract due to collapse of the pharyngeal wall due to a decrease in the tone of the pharyngeal muscles - dilators of the pharynx, abductors of the tongue, pharynx. (iliveok.com)
  • The genioglossus (GG) muscle, which is the main tongue protrusor, has been shown to reduce pharyngeal resistance and collapsibility by far more than other upper airway dilator muscles [ 4 , 5 ], and has become, therefore, the main target for functional stimulation for therapeutic purposes [ 2 , 3 ]. (ersjournals.com)
  • Activation of pharyngeal dilator muscles-the tensor veli palatini, the genioglossus, and the muscles of the hyoid bones (geniohyoid, sternohyoid, and thyrohyoid)-during inspiration counteracts the narrowing effects of reduced intraluminal pressure associated with inspiration. (clinicalgate.com)
  • Serotonin reuptake inhibitors, the mainstay of treatment for depression, may have a slight negative effect on the airway dilator muscles that are responsible for keeping the airway open while we sleep. (tmjsleepsolutions.com)
  • When the pharyngeal muscles, responsible for keeping the airway open, are toned and strengthened through exercises, the likelihood of them becoming lax or collapsing during sleep diminishes. (sleepingbetter.co)
  • The other ventilatory muscles compensate for the increased resistance, and so the airflow decreases much less than the increase in resistance. (wikipedia.org)
  • Pulmonary arterial systolic and diastolic pressure and PAD increase by 4-5mm in NREM sleep Induced transient arousal from NREM sleep cause the following: Increase EMG activity of the diaphragm 150%, increased activity of upper airway dilating muscles 250%, increased airflow and tidal volume 160% and decreased upper airway resistance. (wikipedia.org)
  • Arousals cause return of airway resistance and airflow to near awake values. (wikipedia.org)
  • The passage of airflow through these airways should satisfy the equation of Bernoulli and the law of Poiseuille [1] but it moderately assures these laws, because of its particular anatomical and functional features. (scirp.org)
  • In normal individuals upper airway narrowing increases the resistance to airflow at sleep onset. (scirp.org)
  • 3) The mention of such airway hyperactivity immediately focuses on the asthmatic with intermittent bouts of severe airflow obstruction. (isanagpur.org)
  • Furthermore, if pharyngeal dilators cannot keep the airway open in response to the negative intraluminal pressure induced by inspiration, the upper airway narrows, increasing local airflow velocity (for a given inspiratory volume). (msdmanuals.com)
  • Upper airway resistance syndrome is a condition characterized by increased resistance to airflow during sleep. (sleepingexpert.info)
  • These dilators are inserted into the nostrils to expand the nasal passages, allowing for improved airflow. (generazionetq.org)
  • The primary cause of snoring is the vibration of relaxed and sagging throat tissues, which occurs when there's turbulent airflow due to a partial obstruction in the airway. (sleepingbetter.co)
  • Medication like pain killers, sleeping pills, muscle relaxers, and antihistamines can relax muscles and restrict airflow. (detoxgeek.com)
  • Positional and REM-related OSA patients have lower severity of sleep apnea, suggesting the possibility of lower collapsibility of the upper airway. (researchsquare.com)
  • Obstruction occurs at the level of the root of the tongue, since in this part of the pharynx, its lumen is supported not by bony and cartilaginous formations, but only by the optimal tone of the pharyngeal dilator muscles, mainly the chin-lingual muscle, which prevents the tongue from sinking to the posterior wall of the pharynx. (iliveok.com)
  • It is assumed that there is a defect in controlling the tone of the pharyngeal muscles by specialized structures of the brainstem. (iliveok.com)
  • Apnimed's lead development program targets the neurologic control of upper airway muscles to maintain an open airway during sleep. (biospace.com)
  • The thyrotropin-releasing hormone (TRH) analog taltirelin is of high pre-clinical interest given its neuronal-stimulant properties, minimal endocrine activity, tongue muscle activation following microperfusion into the hypoglossal motor nucleus (HMN) or systemic delivery, and high TRH receptor expression at the HMN compared to rest of the brain. (nature.com)
  • And a research suggested that there were no significant post-volumetric changes of upper airway including tongue volume in 6 months post-surgery, [ 13 ] but it is also not clear if fat content influence surgery outcomes. (biomedcentral.com)
  • Sleep sideways: Sleeping on the back relaxes the muscles and makes the tongue move to the throat, which blocks the passage. (asonor.com)
  • The tongue is the primaty dilator of airway muscles and must be positoned on the roof of the mouth in order to nose breathe. (auroraperiodontal.com)
  • Zennea uses neuro-stimulation technology that externally activates cranial nerves to contract the main dilator muscles of the tongue and reduce upper airway restrictions. (bcbusiness.ca)
  • Your tongue is a muscle, a pretty powerful one at that. (drwiggy.com)
  • Additionally, if you don't have a well-toned tongue posture it could cause hyper-laxative throat dilator muscles . (drwiggy.com)
  • During sleep, there comes a decrease in the tone of the muscles of the tongue and the oropharynx, which causes obstruction of the airways. (iliveok.com)
  • Mouthpieces, also known as mandibular advancement devices, reposition the jaw and tongue to prevent airway collapse. (generazionetq.org)
  • This is the most common cause of snoring and is caused when your tongue relaxes and obstructs your airways while you sleep, causing the air to have to pass through a narrower tunnel. (smartnora.com)
  • Upper airway resistance is expected to be highest during REM sleep because of atonia of the pharyngeal dilator muscles and partial airway collapse. (wikipedia.org)
  • Obstructive Sleep Apnea (OSA) refers to a common sleep disorder that results in hypopnea and hypoxemia caused by repeated collapse of the upper airway during sleep [ 1 ]. (biomedcentral.com)
  • In severe OSA, repetitive upper airways collapse (± hypoxaemia), and subsequent arousal, to reactivate pharyngeal dilator muscles, may occur every minute throughout the night. (nursingjobsexam.com)
  • AD109 has the potential to be the first oral pharmacologic that both treats the underlying cause of OSA, airway obstruction at night, and improves daytime consequences of OSA, such as fatigue. (biospace.com)
  • Apnimed's AD109 has the potential to be the first oral pharmacologic that treats OSA airway obstruction at night. (businesswire.com)
  • In patients with OSA, a reduction in neuromuscular control of the upper airway during sleep leads to a corresponding relaxation of the upper airway dilator muscles. (biospace.com)
  • The action of the Theophylline is guided by the relaxation of the muscles that surround the airways of the pets and clears out the mucus that gets built up inside them. (petcarerx.com)
  • β 2 -AR agonists prevent bronchial airway smooth muscle (ASM) constriction increasing the production of cyclic AMP, the primary mediator of relaxation in the ASM cell [ 5 , 6 ]. (ersjournals.com)
  • This muscle relaxation is increased by neuromuscular diseases (e.g. stroke, dystrophies), age, and muscle relaxants (e.g. sedatives, alcohol). (nursingjobsexam.com)
  • This increased resistance is due to upper airway dilator muscle relaxation and airway narrowing, causing inspiratory flow limitation, snoring, hypoventilation, and ultimately complete obstruction, that is, apnea. (enetmd.com)
  • The relaxation of muscles during sleep can cause the airways to narrow, leading to snoring. (sleepingexpert.info)
  • Sleeping on your side instead of your back can prevent the relaxation of throat muscles and reduce the likelihood of snoring. (generazionetq.org)
  • The spectrum itself (in order of increasing significance) includes primary snoring, upper airway resistance syndrome (UARS), and obstructive sleep apnea hypopnea syndrome (OSAH). (medscape.com)
  • The patients with snoring should be evaluated for nasal airway obstruction. (scirp.org)
  • The differences in neck circumference (NC), linear distance between mandibular plane and hyoid bone (Mp-H), upper airway length (UAL), the maximum thickness of the soft palate (SP max), soft palate length (PNS-U), linear distance between anterior and posterior nasal spine (ANS-PNS), retroglosal width (RS), retroplatal width (RP) between the snoring and non-snoring groups were compared statistically using independent sample t-test. (scirp.org)
  • Elevating the head of your bed by a few inches may help reduce snoring by keeping your airways open. (healthline.com)
  • Check out our review of the Mute Snoring device , a type of internal nasal dilator. (healthline.com)
  • Alcohol can relax the throat muscles, causing snoring. (healthline.com)
  • The snoring problem occurs due to the obstruction in the airway passage inside the throat as it narrows down leading to vibration and sound. (asonor.com)
  • If overweight shed kilos: Once you reduce the tissues near the throat, the airway passage will not narrow helping the oxygen to pass freely in order to reduce the snoring problem. (asonor.com)
  • It helps in opening the airway and reduces snoring. (asonor.com)
  • Quit smoking and reduce alcohol before bedtime: Alcohol intake should be avoided few hours before bedtime as it relaxes the muscles causing loud snoring problem. (asonor.com)
  • another possible cause is enlarged tonsils or adenoids.These problems cause obstruction of the airway,and result in snoring. (enetmd.com)
  • Introduction Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive episodes of upper airway obstruction accompanied by arousal and/or oxygen desaturation.1 The main features of OSAS include loud snoring, excessive sleepiness and non-restorative sleep. (docksci.com)
  • The increased flow velocity promotes flutter directly and decreases intraluminal pressure, further enhancing airway closure and thus promoting flutter and snoring. (msdmanuals.com)
  • Fat deposits around the neck and throat can put pressure on the airway, causing it to narrow and leading to snoring. (generazionetq.org)
  • Oral appliances, also known as snoring mouthguards, are custom-fitted devices that help keep the airway open during sleep. (generazionetq.org)
  • In addition to the traditional nasal strips mentioned earlier, innovative nasal dilators are available that relieve snoring. (generazionetq.org)
  • By activating these muscles, the airway remains open, reducing the occurrence of snoring. (generazionetq.org)
  • It gently pushes the lower jaw out a few millimeters , which opens the airways and stops snoring. (sleepingbetter.co)
  • Exercising the muscles of the throat and airways can play a pivotal role in preventing snoring. (sleepingbetter.co)
  • Congestion causes nasal passages and airways to become constricted, which can block air and result in snoring. (detoxgeek.com)
  • One doctor suggests singing to treat snoring because of the way singing helps to strengthen the muscles in the throat and soft palate. (detoxgeek.com)
  • This can lead to airways which are constricted, and then comes the snoring. (detoxgeek.com)
  • You may wish to consider if nasal dilators may help reduce your snoring. (detoxgeek.com)
  • Try sleeping on your side to help keep your airways open and reduce the likelihood of snoring. (cellphoneforums.net)
  • Avoid alcohol and sedatives: Alcohol and certain medications can relax the throat muscles, potentially causing snoring. (cellphoneforums.net)
  • Consider anti-snoring devices: There are various anti-snoring devices available, such as nasal dilators, snore guards, or chin straps. (cellphoneforums.net)
  • These devices may help keep the airways open during sleep and reduce snoring. (cellphoneforums.net)
  • Snoring occurs when your airway is partially blocked and air can't flow freely. (smartnora.com)
  • The obvious need for new treatment modalities is directed towards two lines of approach: anatomic (such as surgical procedures) and functional, i.e. electrical stimulation of the upper airway dilator muscles [ 2 , 3 ]. (ersjournals.com)
  • Anatomic narrowing may occur at any site in the upper airway from the nasal cavity to the larynx, with many patients/clients affected by OSA having more than one site of obstruction. (cdho.org)
  • Contributing factors are degree of muscle atonia and various anatomic abnormalities that increase airway occlusion (eg, enlarged tonsils, macroglossia, even nasal congestion). (medscape.com)
  • The physiological importance of this normal resting tone is an airway size that provides balance between anatomic dead space and airway resistance to gain efficiency in both gas exchange and work of breathing (Fig. 1). (isanagpur.org)
  • Relationship between anatomic airway dead space (Vd) and airway resistance (Raw) in the normal control state and after bronchodilation and bronchoconstriction. (isanagpur.org)
  • This decrease in intercostal muscle activity is primarily responsible for hypoventilation that occurs in patients with borderline pulmonary function. (wikipedia.org)
  • OSA is characterized by partial or complete upper airway closure that occurs during sleep, which can cause dramatic reductions in overnight oxygen saturation and often leads to poor sleep, and in the long term, has been shown to exacerbate hypertension, diabetes, cardiovascular disease, and stroke. (biospace.com)
  • Anesthesiologist has to be selective regarding the choice of anesthesia technique and the use of drugs in these patients to avoid the provocation of bronchospasm and other airway related complications and if it occurs should recognize and manage appropriately. (isanagpur.org)
  • However, it is important to emphasize that heightened airway reactivity also occurs in patients with chronic bronchitis and emphysema as well as allergic rhinitis and upper and lower respiratory tract infections. (isanagpur.org)
  • Instead, the major sympathetic influence on airway caliber occurs via circulating catecholamines that act primarily on the β2-receptors to produce bronchodilation. (isanagpur.org)
  • OSA occurs due to a loss of pharyngeal dilator muscle tone and increased extra luminal pressure during sleep, producing pharyngeal airway narrowing and occlusion that results in hypopnoeas and apnoeas in susceptible individuals [ 4 ]. (ersjournals.com)
  • Pharyngeal muscle activity and responsiveness are key pathophysiological traits in human obstructive sleep apnea (OSA) and strong contributors to improvements with pharmacotherapy. (nature.com)
  • In central sleep apnea, breathing stops because the chest muscles and diaphragm muscle temporarily cease to work, probably due to a disturbance in the brain's control of breathing. (enetmd.com)
  • Obstructive sleep apnea/hypopnea syndrome (OSAHS) is a common disorder, in which upper airway resistance increases during sleep. (enetmd.com)
  • Nasal symptoms in patients with obstructive sleep apnea and their impact on therapeutic compliance with continuous positive airway pressure. (docksci.com)
  • Obstructive sleep apnea (OSA) is a common medical condition characterized by repetitive occlusions of the upper airway during sleep. (researchsquare.com)
  • Upper airway muscle activation which is reduced during REM sleep rather than during non-rapid eye movement (NREM) sleep, resulting in increased apnea and consequent hypoxemia. (researchsquare.com)
  • When that happens your throat muscles don't have enough strength to keep your airways open all the way which can impede your ability to breathe throughout the night and induce the onset of sleep apnea (a condition where a person will stop breathing through the night for seconds to minutes at a time). (drwiggy.com)
  • There is also the assumption that a decrease in the tone of the pharynx muscles during sleep causes the development of obstructive sleep apnea only if there is a narrowing of the lumen of the upper respiratory tract (the causes of narrowing are indicated below). (iliveok.com)
  • Obstructive Sleep Apnea (OSA) Obstructive sleep apnea (OSA) consists of multiple episodes of partial or complete closure of the upper airway that occur during sleep and lead to breathing cessation (defined as a period of. (msdmanuals.com)
  • This is because it can cause your throat muscles to relax, making you more susceptible to airway obstruction. (healthline.com)
  • Like alcohol, sedatives can also cause muscles such as your throat muscles to relax. (healthline.com)
  • WHEN paramedics or emergency personnel discover a patient who has suffered massive facial or airway trauma, often in situations like a car crash, they may have to perform a cricothyrotomy, which involves stabbing a tube into the patient's throat so they can breath. (theleadsouthaustralia.com.au)
  • When you sing, you are strengthening the throat muscles. (detoxgeek.com)
  • This sounds very odd when you first hear it, but it makes more sense once you learn that it makes your face and throat muscles stronger. (detoxgeek.com)
  • A soft pillow can cause the muscles in your throat to relax too much and make your throat and nose pathways narrower. (detoxgeek.com)
  • Smoking causes your throat to swell, which narrows the airway. (detoxgeek.com)
  • In this position, the throat muscles and other tissues relax, and are more likely to block airways. (detoxgeek.com)
  • Airway resistance increases by about 230% during NREM sleep. (wikipedia.org)
  • It also increases the movement of cilia in the airway, which helps clear out mucus. (petcarerx.com)
  • Rib cage contribution to ventilation increases during NREM sleep, mostly by lateral movement, and is detected by an increase in EMG amplitude during breathing.Diaphragm activity is little increased or unchanged and abdominal muscle activity is slightly increased during these sleep stages. (en-academic.com)
  • It increases the development of skeletal muscles, but you can reduce the training time. (usroidsgear.com)
  • In response to this obstruction, respiratory effort increases and pharyngeal dilator muscles are activated in order to defend the airway. (enetmd.com)
  • How lateral airway tissues affect upper airway dimensions with mandibular advancement in obstructive sleep apnoea. (ers-education.org)
  • Obstructive sleep apnoea is a common sleep disorder where the upper airway collapses repeatedly during sleep, interrupting breathing. (edu.au)
  • Sleep apnoea may be due to upper airways obstruction, described as obstructive sleep apnoea (OSA), or disturbances of control of breathing collectively termed central sleep apnoea (CSA). (nursingjobsexam.com)
  • 11 REM predominant OSA is well known as a result of muscle atonia, but the mechanism of NREM predominant OSA has not yet been fully elucidated. (researchsquare.com)
  • In addition, we expected contraction of this muscle in subjects with a relatively large protrusive part of the GG to have a larger dilatory effect on the pharynx. (ersjournals.com)
  • Oral appliances are a primary treatment option for OSA 4 , as well as an option for patients/clients unable or unwilling to use positive airway pressure approaches. (cdho.org)
  • However, REM-related OSA patients showed significantly larger inferior oral airway space and shorter perpendicular distance between mandibular plane and anterior hyoid bone and the distance between uvula and posterior nasal spine, and narrower maximum width of soft palate than not-REM-related OSA patients. (researchsquare.com)
  • Anesthetizing patients with "reactive airway" remains a challenge to the anesthesiologist. (isanagpur.org)
  • There is always a possibility of catastrophic bronchospasm and other respiratory complications associated with anesthesia in patients with reactive airways. (isanagpur.org)
  • Patients are usually labeled with "reactive airways" if they have a history of cough, sputum production, wheeze, or dyspnea. (isanagpur.org)
  • The exaggerated responses of patients with airway disease have been ascribed to numerous factors like reduced resting airway caliber, presence of mucosal edema and inflammation and the volume of airway secretions. (isanagpur.org)
  • Preoperative identification of patients with reactive airways is important in planning a rational approach for anesthetic care. (isanagpur.org)
  • The pharyngeal airway is further narrowed by obesity, myxoedema, tonsillar enlargement, craniofacial factors (e.g. micrognathia), and specific syndromes (e.g. (nursingjobsexam.com)
  • Development and validation of a computational finite element model of the rabbit upper airway: Simulations of mandibular advancement and tracheal displacement. (neurosleep.org.au)
  • AD109 targets key neurological pathways in OSA that activate upper airway dilator muscles to maintain an open airway during sleep. (biospace.com)
  • AD109 targets key neurological pathways in OSA that cause upper airway obstruction during sleep by activating the upper airway dilator muscles and maintaining an open airway during sleep. (businesswire.com)
  • This medication works to open and relax airways in a variety of ways. (petcarerx.com)
  • This function allows the airways to open. (usroidsgear.com)
  • Nasal dilators, on the other hand, are inserted into the nostrils to keep them open during sleep. (generazionetq.org)
  • Tonic activity of the pharyngeal dilator muscles of the upper airway decreases during the NREM sleep, contributing to the increased resistance, which is reflected in increased esophageal pressure swings during sleep. (wikipedia.org)
  • Intercostal muscle activity decreases in REM sleep and contribution of rib cage to respiration decreases during REM sleep. (wikipedia.org)
  • In addition to this inspiration-associated activation, tonic activity of these muscles during wakefulness helps to stabilize the pharyngeal walls. (clinicalgate.com)
  • A mild tonic constriction exists in all normal human airways. (isanagpur.org)
  • The turbulence leads to vibration of the soft tissues in the collapsible part of the upper airway. (scirp.org)
  • Increased inspiratory muscle strength reduced slope magnitude between Borg rating and peak inspiratory pressure (p = 0.003), but not when pressure was divided by PImax to reflect contraction intensity (p = 0.92). (bvsalud.org)
  • The upper airway dilator muscles are generally activated significantly earlier than the pump muscle in order to allow the airways to be dilated before any negative intrathoracic pressure is created. (ute.edu.ec)
  • You could also try an external nasal dilator, which is a stiffened adhesive strip that's applied on top of the nose across the nostrils. (healthline.com)
  • Internal nasal dilators, which you place inside of your nose, are also available. (healthline.com)
  • In one treatment, air from a compressor is forced into the airway via a mask worn over the nose. (enetmd.com)
  • The compressor of the nose is the transverse nasalis, whereas the dilators are the dilator naris anterior and posterior. (medscape.com)
  • Airway hyperreactivity is a specific term that means that the airways are hyperreactive to a variety of stimuli including methacholine, histamine, hypertonic saline, distilled water, exercise, or eucapnic hyperventilation. (isanagpur.org)
  • The active group trained the inspiratory muscles through progressive threshold loading. (bvsalud.org)
  • During expiratory phase II the inspiratory muscles are inactive allowing passive expiration. (ute.edu.ec)
  • AD109 has the potential to be the first oral pharmacologic that could both treat the underlying nighttime airway obstruction and hypoxia that characterize OSA, as well as improve the daytime consequences of OSA, such as fatigue. (kark.com)
  • Effects of sustained hypoxia on sternohyoid and diaphragm muscle during development. (rcsi.com)
  • Despite the clinical significance, the effects of sustained hypoxia on the form and function of respiratory muscle during development are relatively underexplored. (rcsi.com)
  • The role of reactive oxygen species in hypoxia-induced muscle remodelling was assessed. (rcsi.com)
  • Sustained hypoxia increased sternohyoid muscle force and fatigue in early but not late development, effects that persisted after return to normoxia. (rcsi.com)
  • Hypoxia-induced sternohyoid muscle fatigue was not attributable to fibre type transitions or to a decrease in oxidative capacity. (rcsi.com)
  • Chronic supplementation with the superoxide scavenger tempol did not prevent hypoxia-induced sternohyoid muscle fatigue, suggesting that mechanisms unrelated to oxidative stress underpin hypoxia-induced maladaptation in sternohyoid muscle. (rcsi.com)
  • Sustained hypoxia had no effect on diaphragm muscle fatigue. (rcsi.com)
  • We conclude that there are critical windows during development for hypoxia-induced airway dilator muscle maladaptation. (rcsi.com)
  • Sustained hypoxia-induced impairment of upper airway muscle endurance may persist into later life. (rcsi.com)
  • This study investigated whether respiratory muscle training also affected the respiratory sensations for load detection and magnitude perception. (bvsalud.org)