Allosteric RegulationAllosteric SiteCrystallography, X-RayModels, MolecularReceptors, Metabotropic GlutamateGlutamatesBinding SitesProtein ConformationProtein Structure, TertiaryMolecular Sequence DataProtein BindingAmino Acid SequenceGlutamic AcidReceptor, Metabotropic Glutamate 5CrystallizationReceptors, GlutamateProtein Structure, SecondaryAlcuroniumLigandsGABA ModulatorsStructure-Activity RelationshipGlutamate DehydrogenaseDimerizationPhthalimidesCrystallographyProtein Structure, QuaternaryCatalytic DomainMolecular StructureKineticsSequence Homology, Amino Acidalpha7 Nicotinic Acetylcholine ReceptorDose-Response Relationship, DrugRadioligand AssayReceptors, GABA-AHydrogen BondingGallamine TriethiodideN-MethylscopolamineMutagenesis, Site-DirectedExcitatory Amino Acid AgonistsRecombinant ProteinsGABA-A Receptor AgonistsIsoxazolesReceptors, NicotinicRats, Sprague-DawleyMutationCHO CellsSequence AlignmentNicotinic AgonistsReceptors, Calcium-SensingHEK293 CellsCricetinaeMolecular ConformationBenzothiadiazinesEscherichia coliReceptors, AMPACell LineBacterial ProteinsExcitatory Amino Acid AntagonistsCholinergic AgentsStructural Homology, ProteinSubstrate SpecificityCricetulusReceptor, Muscarinic M1GABA AgonistsProtein SubunitsReceptor, Muscarinic M4Binding, CompetitiveProtein MultimerizationMSH Release-Inhibiting HormoneCatalysisBenzodiazepinesCalciumDrug DesignBicyclo CompoundsModels, ChemicalXenopus laevisSodium GlutamateGABA-B Receptor AgonistsMuscarinic AgonistsAmino Acid Transport System X-AGPyridinesExcitatory Amino Acid AgentsAmino Acid SubstitutionBase SequencePregnanoloneNeuronsReceptors, N-Methyl-D-AspartateReceptor, Muscarinic M2Nootropic AgentsGlutamate SynthaseCells, CulturedPatch-Clamp TechniquesSignal TransductionAspartic AcidProtein FoldingStatic ElectricityCyclohexylaminesDopamine AgonistsPiperidinesPhenylurea Compounds