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Anatomy16

CHO Cells Cells, Cultured Cell Line Neurons Periaqueductal Gray Spinal Cord Brain Vas Deferens Nociceptors Ileum Muscle, Smooth Cell Membrane Nucleus Accumbens HEK293 Cells Locus Coeruleus Corpus Striatum

Organisms10

Rats, Sprague-Dawley Rats, Wistar Guinea Pigs Cricetinae Cricetulus Mice, Inbred C57BL Mice, Knockout Rats, Inbred Strains Mice, Inbred ICR Salvia

Diseases11

Opioid-Related Disorders Pain Substance Withdrawal Syndrome Morphine Dependence Chronic Pain Hyperalgesia Heroin Dependence Pain, Intractable Drug Overdose Disease Models, Animal Pain, Postoperative

Chemicals and Drugs175

Receptors, Opioid, mu Receptors, Opioid Analgesics, Opioid Receptors, Opioid, delta Receptors, Opioid, kappa Opioid Peptides Narcotic Antagonists Naloxone Naltrexone Enkephalin, Ala(2)-MePhe(4)-Gly(5)-Dopamine Agonists Enkephalins Enkephalin, D-Penicillamine (2,5)-Narcotics Morphine Dynorphins Endorphins Enkephalin, Leucine Buprenorphine GABA Agonists Enkephalin, Leucine-2-Alanine Benzeneacetamides Purinergic P1 Receptor Agonists Diprenorphine Muscarinic Agonists Morphinans Adrenergic alpha-2 Receptor Agonists Nicotinic Agonists Pyrrolidines Serotonin 5-HT2 Receptor Agonists beta-Endorphin Adrenergic Agonists Benzomorphans Fentanyl Serotonin 5-HT1 Receptor Agonists Histamine Agonists Analgesics Purinergic P2 Receptor Agonists Methadone Adrenergic alpha-Agonists Adrenergic beta-Agonists GABA-A Receptor Agonists Hydromorphone Ligands Adenosine A1 Receptor Agonists Cholinergic Agonists Piperidines Excitatory Amino Acid Agonists Oligopeptides Cannabinoid Receptor Agonists Guanosine 5'-O-(3-Thiotriphosphate)Adrenergic alpha-1 Receptor Agonists Benzylidene Compounds Diterpenes, Clerodane Ethylketocyclazocine Levorphanol Adrenergic beta-3 Receptor Agonists Heroin Cyclic AMP Adenosine A3 Receptor Agonists Butorphanol GABA-B Receptor Agonists Receptors, Dopamine D2 Serotonin 5-HT4 Receptor Agonists Cyclazocine Azocines Cannabinoids Morphine Derivatives Calcium Analgesics, Non-Narcotic Serotonin Antagonists GTP-Binding Proteins Adenosine Isoproterenol Carbachol Oxymorphone Nalbuphine Prescription Drugs Adenylate Cyclase Purinergic Agonists Receptors, Adrenergic, alpha-2 Receptors, Adrenergic, beta-2 Piperazines Adrenergic beta-1 Receptor Agonists 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine D-Ala(2),MePhe(4),Met(0)-ol-enkephalin Receptors, G-Protein-Coupled Benzazepines Calcium Channel Agonists Receptor, Cannabinoid, CB1 Receptors, Purinergic P1 Receptors, Dopamine D1 Phenethylamines Somatostatin Receptors, Adrenergic, beta Naphthalenes Tetrahydronaphthalenes Pertussis Toxin Baclofen Receptors, Muscarinic Clonidine Parasympathomimetics Dopamine Antagonists Serotonin Quinpirole Colforsin PPAR gamma Pentazocine Alfentanil Receptors, Nicotinic Acetylcholine Loperamide Receptor, Cannabinoid, CB2 Hydrocodone Gonadotropin-Releasing Hormone Norepinephrine Benzoxazines Quinoxalines Pyridines Ergolines RNA, Messenger Muscimol Receptors, Dopamine Receptors, Dopamine D3 Serotonin 5-HT3 Receptor Agonists Adrenergic alpha-Antagonists Tramadol Albuterol Dopamine Purinergic P2X Receptor Agonists Phenylephrine Thiazolidinediones Receptors, Metabotropic Glutamate gamma-Aminobutyric Acid Receptors, sigma Receptor, Adenosine A2A Methadyl Acetate Imidazoles Arrestins Virulence Factors, Bordetella Indoles Sufentanil Cocaine Substance P Codeine Adenosine-5'-(N-ethylcarboxamide)Bicyclo Compounds, Heterocyclic Receptors, Drug Benzamides Yohimbine Receptors, Adrenergic, alpha Apomorphine Capsaicin Receptors, GABA-A Receptors, Purinergic P2 Morpholines Terbutaline Opiate Alkaloids Dronabinol Adrenergic beta-2 Receptor Antagonists Oxotremorine Ethanolamines Clenbuterol GTP-Binding Protein alpha Subunits, Gi-Go Receptors, Neurokinin-1 Peptides Receptor, Serotonin, 5-HT2A Purinergic P2Y Receptor Agonists Propanolamines Histamine Fenoterol Excitatory Amino Acid Antagonists Medetomidine Peptide Fragments Dopamine Agents

Analytical, Diagnostic and Therapeutic Techniques and Equipment18

Pain Measurement Radioligand Assay Analgesia Binding, Competitive Opiate Substitution Treatment Prescription Drug Misuse Injections, Intraventricular Injections, Spinal Electric Stimulation Drug Overdose Microinjections Analysis of Variance Patch-Clamp Techniques Self Administration Transfection Disease Models, Animal Double-Blind Method Pain Management

Psychiatry and Psychology9

Opioid-Related Disorders Pain Substance Withdrawal Syndrome Morphine Dependence Behavior, Animal Heroin Dependence Pain Threshold Motor Activity Conditioning, Operant

Phenomena and Processes22

Dose-Response Relationship, Drug Pain Drug Tolerance Drug Interactions Binding, Competitive Signal Transduction Time Factors Pain Threshold Structure-Activity Relationship Kinetics Motor Activity Muscle Contraction Drug Inverse Agonism Amino Acid Sequence Stereoisomerism Protein Binding Binding Sites Transfection Membrane Potentials Drug Synergism Synaptic Transmission Gene Expression Regulation

Disciplines and Occupations1

Electrophysiology

Information Science2

Amino Acid Sequence Molecular Sequence Data

Health Care3

Analysis of Variance Double-Blind Method Pain Management

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Psychiatry and Psychology Phenomena and Processes Information Science Health Care

Receptors, Opioid, mu Receptors, Opioid Analgesics, Opioid Receptors, Opioid, delta Receptors, Opioid, kappa Opioid Peptides Narcotic Antagonists Naloxone Naltrexone Opioid-Related Disorders Enkephalin, Ala(2)-MePhe(4)-Gly(5)-Dopamine Agonists Enkephalins Enkephalin, D-Penicillamine (2,5)-Narcotics Morphine Dynorphins Endorphins Enkephalin, Leucine Buprenorphine GABA Agonists Dose-Response Relationship, Drug Enkephalin, Leucine-2-Alanine Benzeneacetamides Purinergic P1 Receptor Agonists Diprenorphine Pain Muscarinic Agonists Morphinans Adrenergic alpha-2 Receptor Agonists Nicotinic Agonists Rats, Sprague-Dawley Pyrrolidines Serotonin 5-HT2 Receptor Agonists beta-Endorphin Adrenergic Agonists Benzomorphans Fentanyl Serotonin 5-HT1 Receptor Agonists Pain Measurement Histamine Agonists Analgesics Radioligand Assay Purinergic P2 Receptor Agonists Methadone Adrenergic alpha-Agonists Adrenergic beta-Agonists Drug Tolerance GABA-A Receptor Agonists Hydromorphone Ligands Adenosine A1 Receptor Agonists Cholinergic Agonists Substance Withdrawal Syndrome Analgesia Piperidines Excitatory Amino Acid Agonists Oligopeptides Cannabinoid Receptor Agonists Guanosine 5'-O-(3-Thiotriphosphate)Adrenergic alpha-1 Receptor Agonists Benzylidene Compounds Drug Interactions Rats, Wistar Diterpenes, Clerodane Ethylketocyclazocine Levorphanol CHO Cells Adrenergic beta-3 Receptor Agonists Binding, Competitive Heroin Cyclic AMP Opiate Substitution Treatment Guinea Pigs Adenosine A3 Receptor Agonists Butorphanol Cricetinae Morphine Dependence Cells, Cultured Signal Transduction GABA-B Receptor Agonists Receptors, Dopamine D2 Chronic Pain Behavior, Animal Serotonin 5-HT4 Receptor Agonists Prescription Drug Misuse Cyclazocine Azocines Cannabinoids Morphine Derivatives Cell Line Time Factors Calcium Analgesics, Non-Narcotic Serotonin Antagonists GTP-Binding Proteins Adenosine Hyperalgesia Neurons Isoproterenol

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