Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous lowered white blood cell count (leukopenia, most commonly of neutrophils) and thus causing neutropenia in the circulating blood. (wikipedia.org)
To be precise, neutropenia is the term normally used to describe absolute neutrophil counts (ANCs) of less than 500 cells per microlitre, whereas agranulocytosis is reserved for cases with ANCs of less than 100 cells per microlitre. (wikipedia.org)
List medications that can cause neutropenia and thrombocytopenia, and state drugs that are useful for neutropenia. (ashp.org)
Approximately 1 month into his hospital stay, the patient developed severe isolated neutropenia. (journalmc.org)
Many medications have been implicated as causal agents of neutropenia, but only one case has been reported describing isolated neutropenia induced by amiodarone [ 18 ]. (journalmc.org)
Aplastic anemia2
To formally diagnose agranulocytosis, other pathologies with a similar presentation must be excluded, such as aplastic anemia, paroxysmal nocturnal hemoglobinuria, myelodysplasia and leukemias. (wikipedia.org)
This can be due to bone marrow failure associated with aplastic anemia, leukemia, or chemotherapeutic agents. (wikipedia.org)
Severe1
Agranulocytosis implies a more severe deficiency than granulocytopenia. (wikipedia.org)
Antithyroid drugs1
summarized the literature in 2002 and reported drug-induced neutropenia in a broad range of drug classes including antimicrobials, analgesics, antipsychotics and sedatives, anticonvulsants, antithyroid drugs, cardiovascular drugs, and antihistamines. (medscape.com)
Cases1
Cases with significant confounders and those in which authors provided minimal information about patients were also excluded. (medscape.com)