OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentDisciplines and OccupationsHealth Care
ChromoblastomycosisPhialophoraAscomycotaMitosporic FungiItraconazoleExophialaPotassium IodideAntifungal AgentsCarcinoma, Basal CellDermatologyCross-Sectional StudiesSkin NeoplasmsTattooingPhotosensitivity DisordersMeningitis, Aseptic
CausativeHistoplasmosisEtiologicalMelanized fungiCutaneousPedrosoiMycosesChromomycosisPhaeohyphomycosisFungal infectionCausalFonsecaeaSpeciesEtiologic agentLesionsClinicalCarrioniiInvasiveImplantationAntifungal agentBrazilDiseasesImidazoleDiseaseInhibitorsItraconazoleCasesCellsYearsPatientsHumanResearch
Causative6
  • The causative agents are mainly Fonsecaea spp. (cdc.gov)
  • The species belonging to the genus Fonsecaea are the main causative agents of chromoblastomycosis . (bvsalud.org)
  • to determine the demographic characteristics, clinical presentation of cases and identification of the causative agents of implantation mycosis and cutaneous nocardiosis from the records of the Mycology section of the Central Laboratory in the period 1997-2019. (bvsalud.org)
  • Dermatophytes of the genera Trichophyton and Microsporum are the most common causative agents. (wikipedia.org)
  • Microscopic tissue reactions may be primarily suppurative or granulomatous depending on the specific causative agent. (msdmanuals.com)
  • Causative agents can be identified presumptively by gross and microscopic examination of grains from exudates, which contain pathognomonic, irregularly shaped, variably colored, 0.5- to 2-mm granules. (msdmanuals.com)
Histoplasmosis2
  • The Expert Committee recommended the addition of itraconazole to the EML and the EMLc for treatment of chronic cavitary pulmonary aspergillosis, histoplasmosis, sporotrichosis, paracoccidioidomycosis, infections caused by Talaromyces marneffei and chromoblastomycosis, and for prophylaxis of histoplasmosis and infections caused by T. marneffei in AIDS patients. (essentialmeds.org)
  • Oral Nizoral (tablets) is used to treat South American blastomycosis, valley fever, chromoblastomycosis, histoplasmosis, blastomycetic dermatitis and other systemic fungal diseases in children older than 2 years and adults. (reliableonlinepharmacy.org)
Etiological3
  • A kalrae has been documented in onychomycosis and has been recovered from the skin, nails, and respiratory sites but has not been established as an etiological agent. (black-mold.com)
  • The genus Fonsecaea is one of the etiological agents of chromoblastomycosis (CBM), a chronic subcutaneous disease that is difficult to treat. (tudublin.ie)
  • Additionally, we identified a reduction of carbohydrate degrading enzymes, specifically many of the Glycosyl Hydrolase (GH) class, while most of the Pectin Lyase (PL) genes were lost in etiological agents of chromoblastomycosis and phaeohyphomycosis. (nau.edu)
Melanized fungi1
  • Chromoblastomycosis is a chronic, implantation, fungal disease caused by melanized fungi from a variety of genera of the order Chaetothyriales. (cdc.gov)
Cutaneous4
  • sporotrichosis, chromoblastomycosis and mousetomas (implantation mycosis) and cutaneous nocardiosis are mainly caused by traumatic inoculation of fungi and bacteria from the environment. (bvsalud.org)
  • 11 patients were found with sporotrichosis (Sporothrix schenkii complex), 21 with chromoblastomycosis (Fonsecae pedrosoi complex 47.6%, Phialophora verrucosa 4.7%), 4 mice (Scedosporium apiospermum, Acremonium kiliensi, Fusarium solani and Nocardia brasiliens) and 7 cutaneous nocardiosis (3 Nocardia brasiliensis, 2 Nocardia farcinica, 1 Nocardia transvalensis and 1 Nocardia sp. (bvsalud.org)
  • Has been used as a photosensitizer for photodynamic therapy † [off-label] (PDT) for topical treatment of dermatologic or mucocutaneous infections (e.g., herpes labialis, eczema herpeticum, oral candidiasis, cutaneous leishmaniasis, chromoblastomycosis) or chronic dermatologic or mucocutaneous conditions (e.g., plaque psoriasis, oral lichen planus). (drugs.com)
  • Partial improvement: cutaneous sporotricosis and chromoblastomycosis. (pharmacology2000.com)
Pedrosoi1
  • Chromoblastomycosis is a chronic fungal infection of the skin and the subcutaneous tissue caused by traumatic inoculation of a specific group of dematiaceous fungi (usually Fonsecaea pedrosoi, Phialophora verrucosa, Cladosporium carrionii, or Fonsecaea compacta ) through the skin. (medscape.com)
Mycoses1
  • As is the case for other implantation mycoses, chromoblastomycosis lesions are located mainly on the lower limbs, particularly on the dorsal face of the feet, ankles, and legs ( 1 , 4 - 6 ). (cdc.gov)
Chromomycosis1
Phaeohyphomycosis1
  • The order Chaetothyriales (Pezizomycotina, Ascomycetes) harbours obligatorily melanised fungi and includes numerous etiologic agents of chromoblastomycosis, phaeohyphomycosis and other diseases of vertebrate hosts. (nau.edu)
Fungal infection1
  • Chromoblastomycosis is an implantation fungal infection. (cdc.gov)
Causal3
  • Causal agents of chromoblastomycosis (chromomycetes). (wikipedia.org)
  • After 1 month of cotic mycetoma depending on the causal therapy and management of lesions for 2 agent. (who.int)
  • The Amazonian nucleus of the ICB found strong evidence of an as yet unknown species of a protozoon of the Leishmania genus, which could be a new causal agent of American tegumentary leishmaniasis (ATL), and infectious disease that every year attacks the mucous tissues of 28,000 Brazilians, from the north to the south of the country. (fapesp.br)
Fonsecaea2
Species6
  • [ 15 ] Rare cases of chromoblastomycosis caused by Rhinocladiella aquaspersa and Exophiala species have also been reported, allowing the inclusion of these species among those that cause the disease. (medscape.com)
  • Therefore, the present study aimed to propose new molecular tools to differentiate between sibling species causing chromoblastomycosis . (bvsalud.org)
  • The results showed that markers and probes could effectively discriminate the species in both clinical and environmental samples, enabling bioprospecting of agents of chromoblastomycosis , thereby elucidating the infection route of the disease . (bvsalud.org)
  • Molecular Epidemiology of Agents of Human Chromoblastomycosis in Brazil with the Description of Two Novel Species. (cdc.gov)
  • Local debridement should be performed and topical antifungal agents (e.g., natamycin and amphotericin B) considered if Fusarium species are identified. (ventsistema.net)
  • Identifying the specific pathogen is critical, because Fusarium species have variable susceptibilities to the antifungal agents that are currently used. (ventsistema.net)
Etiologic agent2
  • nov., the etiologic agent of lobomycosis. (atlasclinicalfungi.org)
  • However, unless special techniques such as immunofluorescence are used, or the infecting fungus possesses unique structures such as spherules, definitive identification of the etiologic agent by histopathology is difficult. (drfungus.org)
Lesions2
  • Chromoblastomycosis was 3 times more likely to consist of leg lesions (p = 0.003). (cdc.gov)
  • The clinical manifestation of chromoblastomycosis is polymorphous but is dominated by verrucous and tumoral lesions resembling cauliflower. (cdc.gov)
Clinical3
  • More recently, the advent of immunosuppressive therapies and diseases brought more confusion because of the identification of new agents and clinical settings. (medscape.com)
  • The features of chromoblastomycosis are distinctive enough to consider chromoblastomycosis an independent clinical entity. (medscape.com)
  • [ 10 ] mentioned that in Cuba in 1908 Guiteras had observed 10 cases of a disease known as chapa in which the clinical aspects resembled those of chromoblastomycosis. (medscape.com)
Carrionii1
Invasive1
  • Absidia cormbifera has been an invasive infection agent in AIDS and neutropenic patients, as well as, agents of bovine mycotic abortions, and feline subcutaneous abscesses. (black-mold.com)
Implantation1
Antifungal agent3
  • An imidazole antifungal agent that is used topically and by intravenous infusion. (lookformedical.com)
  • A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis. (lookformedical.com)
  • Nizoral is an antifungal agent used for the treatment of local and systemic fungal infections in children and adults. (reliableonlinepharmacy.org)
Brazil1
  • In the view of the ICB and Cepem specialists' views, identifying and treating the asymptomatic carriers of P. vixax is just as important for holding back malaria advance as putting into practice the traditional control measures for this endemic disease: combating the transmitting agent, the so-called vector (in Brazil, female Anopheles darlingi mosquitoes infected with the plasmodium) and to medicate as quickly as possible the symptomatic cases. (fapesp.br)
Diseases1
  • It is provided as an additional code where it is desired to identify the bacterial agent in diseases classified elsewhere. (cdc.gov)
Imidazole1
Disease2
  • [ 6 ] the International Society for Human and Animal Mycology (ISHAM) recommended that the best name to define the disease was chromoblastomycosis, which Terra et al coined in 1922. (medscape.com)
  • The Latin names are for the conditions (disease patterns), not the agents that cause them. (wikipedia.org)
Inhibitors2
  • This latter observation highlights components of these DDR paths as possible therapeutic targets for the development of small molecule inhibitors that could enhance the sensitivity of tumefaction cells to the cytotoxic ramifications of radio /chemo therapeutic agents. (hdacassay.com)
  • The notion of applying small molecule inhibitors to interrupt ATM function and sensitize tumefaction cells to radio /chemo therapeutic agents is not a novel concept. (hdacassay.com)
Itraconazole3
  • Flucytosine must not be used as a sole agent in life-threatening fungal infections due to relatively weak antifungal effects and fast development of resistance, but rather in combination with amphotericin B and/or azole antifungals such as fluconazole or itraconazole . (mdwiki.org)
  • The Committee considered that itraconazole could be interpreted to be an eligible alternative agent within the existing square box listing of fluconazole. (essentialmeds.org)
  • The Committee noted that itraconazole demonstrated similar efficacy to fluconazole for many indications but is inferior to other antifungal agents in other settings (e.g. induction and maintenance therapy for cryptococcal meningitis). (essentialmeds.org)
Cases1
Cells2
  • Muriform cells are specific to chromoblastomycosis and described as large brown, thick-walled, compartmented cells. (cdc.gov)
  • Studies of cells that are functionally mGluR defective in different components of the DDR pathways}, reduced ability to repair damaged DNA and a heightened sensitivity to IR and other DNA damaging agents. (hdacassay.com)
Years2
  • Patients with chromoblastomycosis were older (47.9 years) than those without (37.5 years) (p = 0.0005). (cdc.gov)
  • We highlight the persistence of a high level of chromoblastomycosis endemicity, which was even greater at some locations than 20 years ago. (cdc.gov)
Patients2
  • Chromoblastomycosis was diagnosed in 50 (33.8%) of 148 patients. (cdc.gov)
  • Despite the fact that long lasting remedy with TCZ is properly tolerated, it goes Chromoblastomycosis devoid of saying that it's advantageous not just for the patients but also for health-related economic climate. (cox-inhibitors.com)
Human1
  • The agents often gain entry into the human body by contact with wood splinters or thorns. (medscape.com)
Research1
  • During the existing research, we set out to uncover agents not known for targeting lung adenocarcinoma by an expression-based in silico screening. (thrombin-inhibitor.com)