• In this study, ofCS was purified by affinity chromatography using rVAR2 and subjected to detailed structural analysis. (lu.se)
  • Li M, Petukh M, Alexov E, Panchenko A, Predicting the Impact of Missense Mutations on Protein-Protein Binding Affinity,J Chem Theory Comput:1770-1780. (lu.se)
  • Zhang C, Zheng W, Zhang Y, BindProfX: Assessing Mutation-Induced Binding Affinity Change by Protein Interface Profiles with Pseudo-Counts, J Mol Biol. (lu.se)
  • Huang X, Zheng W, Pearce R, Zhang Y, Huang X, Zheng W, Pearce R, Zhang Y, SSIPe: accurately estimating protein-protein binding affinity change upon mutations using evolutionary profiles in combination with an optimized physical energy function, Bioinformatics;36(8):2429-2437. (lu.se)
  • Wang M, Cang Z, Wei G, A topology-based network tree for the prediction of protein-protein binding affinity changes following mutation, Nat Mach Intell):116-123. (lu.se)
  • A superb gateway into the time-honored Fender® family, the Squier® Affinity Series® Jaguar® Bass H delivers legendary design and quintessential tone for today's aspiring bassist. (fender.com)
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  • It also elicits moderate affinity for serotonin receptors. (medscape.com)
  • This antibody was raised against rat somatostatin receptor-4 (SSTR4) and recognizes SSTR4 in rat. (atsbio.com)
  • DOTA antibody reporter 1 (DAbR1) comprises a single-chain fragment of the antilanthanoid-DOTA antibody 2D12.5/G54C fused to the human CD4-transmembrane domain and binds irreversibly to lanthanoid ( S )-2-(4-acrylamidobenzyl)-DOTA (AABD). (snmjournals.org)
  • Pires D, Ascher D, mCSM-AB: a web server for predicting antibody-antigen affinity changes upon mutation with graph-based signatures, Nucleic Acids Res. (lu.se)
  • Construction of Affinity Living Circle Square commenced in 2018 and was completed in 2021. (wikipedia.org)
  • Etrasimod is an oral sphingosine-1-phosphate (S1P) receptor that binds with high affinity to receptors 1, 4, and 5. (medscape.com)
  • Norrin binds with the receptor frizzled-4 (produced from the FZD4 gene), fitting together like a key in a lock. (medlineplus.gov)
  • The new 1.7 versions of both Affinity Photo and Affinity Designer are currently on sale in both the App Store and on Affinity's store, with a 20% discount ($39.99 for desktop, $15.99 for iPad) with no subscription fees. (appleinsider.com)
  • The developer has released Affinity Version 2 apps that not only include major new features (more on those shortly), but the first edition of Publisher for the iPad. (yahoo.com)
  • You now have all of the Affinity bundle on your tablet, and won't have to split your attention between your computer and iPad when it's time to design a page layout. (yahoo.com)
  • You can buy the individual Affinity Version 2 apps for $70 on the desktop ($41 on sale) and $20 (currently $12) on the iPad. (yahoo.com)
  • Streptococcus pneumoniae and Neisseria meningitidis have very similar mechanisms of resistance to penicillin G, which are mediated by the decreased affinity of penicillin-binding proteins (PBPs) ( 1 - 3 ). (cdc.gov)
  • Affinity Publisher 2 now helps you add academia-friendly footnotes, endnotes and sidenotes. (yahoo.com)
  • 125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor. (aspetjournals.org)
  • Somatostatin Receptor-4 is one of five receptor subtypes termed SSTR1-5. (atsbio.com)
  • The norrin protein and its receptor frizzled-4 participate in developmental processes that are believed to be crucial for normal development of the eye and other body systems. (medlineplus.gov)
  • Effect of explicit water molecules on ligand-binding affinities calculated with the MM/GBSA approach. (lu.se)
  • Looking to remove a background in Affinity Photo ? (digital-photography-school.com)
  • Affinity Photo will detect when your Brush is near an edge and adjust the selection automatically. (digital-photography-school.com)
  • Brushes in Affinity Photo go far beyond the standard circular brush most of us are probably familiar with. (digitalcameraworld.com)
  • Serif's Affinity Photo and Affinity Designer have received updates to version 1.7 today, receiving enhanced GPU compute acceleration, HDR monitor support, and a new memory management system. (appleinsider.com)
  • Using Affinity Photo with an HDR monitor offers a simply stunning experience," says Serif Managing Director Ashley Hewson. (appleinsider.com)
  • It's amazing the detail and dynamic range the latest SLR cameras capture when shooting in RAW, and Affinity Photo now offers the opportunity to actually see all that depth while editing on an HDR monitor. (appleinsider.com)
  • In this batch of updates, Affinity Photo has an improved RAW processing engine designed to load files faster, a rewritten brush engine and new brushes, a symmetry mode, and improved batch processing. (appleinsider.com)
  • Affinity Photo 2 now includes non-destructive RAW development, saved layer states, compound masks (that is, joining multiple masks together), live warping and live masks for elements like hue and luminosity ranges. (yahoo.com)
  • I recently updated Affinity Photo, and a few days after, Affinity Designer. (serif.com)
  • But thankfully, this hasn't stopped us working hard on our apps and bringing you another update-say hello to version 1.8.4. (affinityspotlight.com)
  • Affinity apps are now ready for the launch of Big Sur and iOS 14. (affinityspotlight.com)
  • Alternatively, the Affinity v1.8.4 apps are available to purchase for a one-off payment with no subscription. (affinityspotlight.com)
  • Serif Affinity Designer license key was built for today's fast computing hardware: live, responsive and fluid design make Affinity Designer an absolute joy to use. (textise.net)
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  • From branding, concept art, project printing icons user interface UX web mockups Affinity Designer will transform your work on macOS and Windows alike - regardless if its branding concept art project printing icons user interface UX web mockups etc… it has you covered from branding through to concept art project printing icons user interface UX and web mockups! (textise.net)
  • Created to meet specific workflow needs on both platforms in both environments its record structure delivers amazing results while creating seamless uninterrupted views - as long as your zoomed out 10,000,000 times before starting on either platform Affinity Designer will transform how you are involved! (textise.net)
  • Serif Affinity Designer Serial Key has transformed from an incredible, precise pen into an extremely smooth gradient tool the tools necessary for professional vector design application. (textise.net)
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  • A 60fps pan and 10,000,000% zoom allows you to keep an eye on all changes, impacts and brushes with an instant eye-blink display of continuous pixels for standard or retinal targets that shows real time continuous results and Affinity Designer delivers them for you - getting you closer than ever to creating perfect vector results! (textise.net)
  • Serif Affinity Designer is an unparalleled vector illustration program and professional graphic design application, boasting revolutionary new drawing tools, approaches, and features even before its predecessor - Adobe Illustrator or Serif Affinity Designer - had made available. (textise.net)
  • Serif Affinity Designer License Key provides users with everything they need to design stunning landscapes, quickly add animation, easily access watermarks and delete unneeded elements without much fuss - this software supports numerous languages worldwide and supports every design format including PSDs SVG EPS PDF PDF/X PDF/FH Drawing paragraph styles making this program truly amazing from every aspect. (textise.net)
  • Along with its excellent grids, Affinity Designer also has a powerful snapping management system. (tutsplus.com)
  • Affinity Designer 2, meanwhile, adds non-destructive vector warping, a 'knife' cutting tool, a shape builder and even tools for measuring lengths and areas. (yahoo.com)
  • NDP gene mutations that cause this condition affect the ability of the norrin protein to bind with frizzled-4, interfering with the specialization of retinal cells for their unique sensory function. (medlineplus.gov)
  • A Large-Scale Test of Free-Energy Simulation Estimates of Protein-Ligand Binding Affinities. (lu.se)
  • A semiempirical approach to ligand-binding affinities: Dependence on the Hamiltonian and corrections. (lu.se)
  • They have their own [link=https://affinity.serif.com/en-us/learn/]"Learn" pages[/link] with tutorials and if those aren't good enough then there are lots on YouTube as well. (ephotozine.com)
  • Thus, among children with high exposure, the can induce an increase in IgG and IgG4 antibodies with a odds of sensitisation to mite rather than cat was 4·0 decrease in IgE antibodies,16,17 and that expression of the (99% CI 1·49-10·00). (cdc.gov)
  • This model is specific to the mechanism of resistance to penicillin G common to S. pneumoniae and N. meningitidis and mediated by the decrease in affinity of their PBPs. (cdc.gov)
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  • N6-2-(4-Amino-3-[125I]iodophenyl)ethyladenosine, a high affinity A1AR agonist, has served as the only radioligand available for study of the A3AR. (aspetjournals.org)
  • This report characterizes 125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine (125I-AB-MECA), a high affinity radioligand for the A3AR, in two cell lines that express this AR subtype. (aspetjournals.org)
  • Affinity Living Circle Square is a 116 m (381 ft) tall, 36-storey residential high-rise building in Manchester, England. (wikipedia.org)
  • Recombinant subfragments of VAR2CSA (rVAR2) have also been shown to bind specifically and with high affinity to cancer cells and tissues, suggesting the presence of a shared type of oncofetal chondroitin sulfate (ofCS) in the placenta and in tumors. (lu.se)
  • We found high levels of N-acetylgalactosamine 4-O-sulfation (∼80-85%) in placenta- and tumor-derived ofCS. (lu.se)
  • With affinity mapping, you can organize ideas from a brainstorming session into groups based on which ideas are conceptually similar to each other, and then give each group a summary statement that describes its main idea. (gliffy.com)
  • With an affinity diagram, you can group like questions together to consolidate ideas and take next steps. (gliffy.com)
  • The King County Latinx Affinity Group (KCLx)'s mission is to build equitable community for King County Latinx employees and the Latinx community at large. (surveymonkey.com)
  • 4 . If you've participated in KCLx, what did you hope to gain by joining the affinity group? (surveymonkey.com)
  • Results: NGS detected 130 risk variants associated with DA (3.1 × 10-6 to 6.21 × 10-4), 129 of which were located in noncoding regions. (cdc.gov)
  • This level of 4-O-sulfation was also found in other tissues that do not support parasite sequestration, suggesting that VAR2CSA tropism is not exclusively determined by placenta- and tumor-specific sulfation. (lu.se)
  • However, this virus also has a greater affinity for infecting lower respiratory tract tissues than seasonal influenza viruses, resulting in many cases of viral pneumonia that are rapidly progressive, difficult to treat, and often fatal. (who.int)
  • Serif is determined to make its Affinity suite a more practical alternative for creatives who'd rather not pay for an Adobe subscription - or use a conventional PC, for that matter. (yahoo.com)
  • You can read our article about How to install Affinity updates if you need some help with installation. (affinityspotlight.com)
  • One of the best things about using brushes in Affinity is how the brush tip shows a preview of the stroke before you start painting - including any colour, opacity or blend settings applied - so you can see how each stroke will affect your image. (digitalcameraworld.com)
  • Image showing periodicity of electron affinity for 6s, 6p, and 6d chemical elements. (webelements.com)
  • Removes the Negative Affinity effects from gameplay. (nexusmods.com)
  • This theoretical work analyzes the practice developed by the Swiss doctor, searching for the affinities between symptoms in some psychopathological conditions that are difficult to understand. (bvsalud.org)
  • But any type of team can use an affinity diagram to organize research or feedback, not just product and UX. (gliffy.com)
  • We've opened our portrait, then grabbed the Selection Brush from the Affinity toolbar and paint over the subject to select her. (digitalcameraworld.com)
  • When creating an affinity diagram, you should not start with predetermined themes and come up with ideas that fit those themes. (gliffy.com)
  • Premium" is used for all things luxe, but that's just the start of the story for the new Affinity Cycles Premium Carbon Fiber Levers. (feedthehabit.com)
  • Affinity Living Circle Square includes a gym, private dining rooms, residents' lounges, co-working spaces, and rooftop terraces. (wikipedia.org)
  • You'd normally pay $170 for the entire Affinity suite across all platforms, but a launch sale drops that price to $100 . (yahoo.com)
  • With regular dosing, a steady state is reached within 4 days. (medscape.com)
  • There are many brainstorming techniques that produce a wide variety of ideas-ideas that affinity mapping can be helpful in organizing. (gliffy.com)
  • Just gone from an old Elements to Affinity software and I am very impressed with it. (ephotozine.com)
  • S. pneumoniae strains with decreased susceptibility have been found frequently over the last decade, and most of them now have a penicillin G MIC greater than 2 µg/mL ( 4 , 5 ). (cdc.gov)
  • Binding affinities in the SAMPL3 trypsin and host-guest blind tests estimated with the MM/PBSA and LIE methods. (lu.se)
  • The aim of the study was to determine the of the drug [4,5,7,9,11-13]. (who.int)