• Six diatom species displayed specific anti-inflammatory, anticancer (blocking human melanoma cell proliferation), and anti-biofilm (against the bacteria Staphylococcus epidermidis ) activities whereas, none of the other microalgae were bioactive against the conditions tested for. (frontiersin.org)
  • Testing the susceptibility of Staphylococcus aureus to antibiotics by the Kirby-Bauer disk diffusion method - antibiotics diffuse from antibiotic-containing disks and inhibit growth of S. aureus , resulting in a zone of inhibition. (wikipedia.org)
  • 2015. Nisin incorporated with 2,3-dihydroxybenzoic acid in nanofibers inhibits biofilm formation by a methicillin-resistant strain of Staphylococcus aureus . (sasm.org.za)
  • Treatment of established biofilm with NEBB resulted in biofilm-disruption, involving significant reductions in biofilm mass and metabolic activity for Candida and both Staphylococcus species. (jmb.or.kr)
  • Staphylococcus aureus merupakan salah satu bakteri yang dapat membentuk biofilm dan merupakan salah satu penyebab RSK. (ub.ac.id)
  • Pembentukan biofilm Staphylococcus aureus melalui 4 tahap yaitu tahap perlekatan, quorum sensing (QS), maturasi dan pelepasan, QS merupakan tahap paling penting pada proses pembentukan biofilm. (ub.ac.id)
  • Malang Indonesia sebagai QSI pada isolat biofilm Staphylococcus aureus dari RSK berdasarkan penurunan AIP, histidine kinase, ekspresi gen agr dan morfologi biofilm. (ub.ac.id)
  • Malang Indonesia sebagai QSI pada isolat biofilm Staphylococcus aureus dari RSK. (ub.ac.id)
  • Kultur Congo Red didapatkan biofilm Staphylococcus aureus berwarna hitam. (ub.ac.id)
  • The effects of these NPs on Acinetobacter baumannii , Staphylococcus aureus , and Escherichia coli biofilms were studied using quantitative biofilm inhibition and disruption assays, as well as using fluorescence, -scanning electron microscopy, and atomic force microscopy. (dovepress.com)
  • Bacteria have evolved multiple strategies for causing infections that include producing virulence factors, undertaking motility, developing biofilms and invading host cells. (nature.com)
  • Biofilms form when groups of bacteria cover themselves in a sticky mixture of sugars, protein, and DNA. (the-scientist.com)
  • Within the biofilm, bacteria take on different responsibilities. (the-scientist.com)
  • Biofilm is a complex matrix consisting of extracellular polysaccharides, DNA, and proteins that protect bacteria from a variety of physical, chemical, and biological stresses allowing them to survive in hostile environments. (intechopen.com)
  • Bacteria can be found in planktonic form or in specific conditions, as sessile aggregates on both biotic and abiotic surfaces originating complex structures known as biofilm. (intechopen.com)
  • The biofilm matrix consists of polysaccharides, proteins, and DNA and constitutes a stubborn source that protects bacteria from a variety of physical, chemical, and biological stresses. (intechopen.com)
  • [13] The biofilm bacteria can share nutrients and are sheltered from harmful factors in the environment, such as desiccation, antibiotics, and a host body's immune system. (wikipedia.org)
  • They can be found very early in Earth's fossil records (about 3.25 billion years ago) as both Archaea and Bacteria, and commonly protect prokaryotic cells by providing them with homeostasis, encouraging the development of complex interactions between the cells in the biofilm. (wikipedia.org)
  • [8] [5] The first colonist bacteria of a biofilm may adhere to the surface initially by the weak van der Waals forces and hydrophobic effects. (wikipedia.org)
  • The present authors hypothesised that bronchoscopy with protected specimen brush may sample biofilm-forming bacteria adherent to the airway wall, whereas traditional sputum collection may not. (ersjournals.com)
  • Retrieved bacteria were genotyped, and grown in planktonic cultures and as biofilms, and susceptibilities to individual antibiotics and to antibiotic combinations were determined. (ersjournals.com)
  • Susceptibility to single antibiotics and to antibiotic combinations were not different between planktonically or biofilm-grown bacteria derived from sputum, as compared to those obtained by bronchoalveolar lavage and protected brush. (ersjournals.com)
  • One problem with relying on sputum samples to guide therapy is that biofilm bacteria may not be adequately sampled via sputum, since sputum expectoration only samples P. aeruginosa that have detached and dispersed from the airway biofilm 5 , 6 . (ersjournals.com)
  • However, studies have not previously been done to determine whether bacteria retrieved from sputum are more susceptible to antibiotics compared to bacteria retrieved directly from the airway biofilm. (ersjournals.com)
  • Thus, it is possible that PSB may directly recover P. aeruginosa bacteria that have aggregated as biofilms and adhered to the surface of the airway. (ersjournals.com)
  • 1,2 The unique structure of biofilms protects bacteria from the surrounding environment, conferring a capacity for persistence against phagocytosis, oxidative stresses, nutrient/oxygen restriction, metabolic waste accumulation, interspecies competition, and conventional antimicrobial agents. (rsc.org)
  • 2,9-11 A comprehensive understanding of the interactions between bacteria and materials with different surface topographies may pave the way for more effective strategies to control biofilm growth. (rsc.org)
  • Bacteria often switch from a free-living lifestyle to a surface adapted, structured lifestyle known as a biofilm. (southampton.ac.uk)
  • We isolated and named this phage, showed that it becomes superinfective to its host during biofilm development, and found that it plays a role in phenotypic diversification of biofilm bacteria. (southampton.ac.uk)
  • [1] [2] They may either kill or inhibit the growth of bacteria. (wikipedia.org)
  • In current usage, the term "antibiotic" is applied to any medication that kills bacteria or inhibits their growth, regardless of whether that medication is produced by a microorganism or not. (wikipedia.org)
  • On the other hand, etrasimod was shown to inhibit quorum sensing (QS) signaling in Chromobacterium violaceum, suggesting that it may block the biofilm formation by targeting QS in certain Gram-negative bacteria. (helsinki.fi)
  • 2014. 2,3- dihydroxybenzoic acid electrospun into poly (D, L-lactide)(PDLLA)/poly (ethylene oxide)(PEO) nanofibers inhibited the growth of Gram-positive and Gram-negative bacteria . (sasm.org.za)
  • The scientists also cultivated biofilms with the bacteria strains, against which IDSK was tested. (food-safety.com)
  • At a concentration of 0.125 M, P. aeruginosa , E. coli and S. enterica exhibited 51 percent, 55 percent, and 66 percent inhibition of bacteria growth, respectively. (food-safety.com)
  • In this work, the antibiofilm effect of Ag nanoparticle (AgNP) combined with the quorum sensing inhibitor (QSI) 4-nitropyridine N-oxide (4NPO) on P. aeruginosa biofilms was investigated. (cheric.org)
  • A related strategy encompasses synthesis of compounds that inhibit the two P. aeruginosa quorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation. (justia.com)
  • The inhibition of quorum sensing, called quorum quenching, may disrupt oral biofilm formation, which is the main etiological factor of oral diseases, including periodontitis. (mdpi.com)
  • Quorum sensing Inhibitor (QSI) merupakan salah satu pendekatan strategis untuk pengembangan terapi baru pengobatan biofilm bakteri. (ub.ac.id)
  • Cells may also communicate via quorum sensing, which may in turn affect biofilm processes such as detachment. (cdc.gov)
  • In this section, we will focus on proteins involved in biofilm formation as useful targets for the development of new drugs that can effectively and specifically impair biofilm formation with slight effects on cell survival, thus avoiding the generation of drug-resistant strains. (intechopen.com)
  • Any drug impairing crucial processes for bacterial life will inevitably lead to the development of drug-resistant strains, whereas the inhibition of biofilm formation might prevent the onset of bacterial resistance. (intechopen.com)
  • A total of 10 patients (83%) had a single strain of P. aeruginosa found using sputum, bronchoalveolar lavage and protected brush techniques, and two patients (17%) had two strains recovered in sputum, but only one strain was recovered using bronchoscopic techniques. (ersjournals.com)
  • 7 Additionally, P. aeruginosa is intrinsically resistant to a variety of antibiotics and disinfectants and multi-drug resistant (MDR) strains have been identified. (rsc.org)
  • The strains were allowed to form biofilm in vitro. (jmb.or.kr)
  • After 20 hours of exposure to IDSK, all strains showed a total inhibition of planktonic cell growth up to 0.25 molal concentration (M), representing the lowest concentration of IDSK at which bacterial growth is completely inhibited. (food-safety.com)
  • Biofilm formation requires three different stages: cell attachment to a solid substrate, adhesion, and growth. (intechopen.com)
  • The formation of a biofilm begins with the attachment of free-floating microorganisms to a surface. (wikipedia.org)
  • The virulence factors of Candida albicans are germ tube and biofilm formation, adherence to host tissues, and production of hydrolytic enzymes. (hindawi.com)
  • angustifolia extract on the germ tube and biofilm formation of C. albicans . (hindawi.com)
  • SEM results showed concentration dependent reduction in biofilm and hyphae formation. (hindawi.com)
  • DVA extract has ability to reduce virulence of C. albicans by inhibiting germ tube and biofilm formation through damage to the cell wall. (hindawi.com)
  • Pathogenic characteristics such as germ tube and biofilm formation and production of tissue damaging enzymes are possible targets of new drugs. (hindawi.com)
  • The present study investigated the effect of subinhibitory concentration of crude extract of DVA on the germ tube and biofilm formation by C. albicans . (hindawi.com)
  • Therapeutic failures of antibiotics used to treat macrolide-susceptible Streptococcus pyogenes infections may be due to biofilm formation. (microbiologyresearch.org)
  • Fibrinogen induces biofilm formation by Streptococcus suis and enhances its antibiotic resistance. (microbiologyresearch.org)
  • Biofilm formation has been found in 95% of patients intubated with endo-tracheal tubes for more than 24h. (ibecbarcelona.eu)
  • It is also a relevant pathogen in chronic wounds infections and skin injuries , and in keratitis, a common corneal infection related with bacterial biofilm formation over contact lenses. (ibecbarcelona.eu)
  • 3,6 Biofilm formation by P. aeruginosa is responsible for antimicrobial tolerance and causes major problems for treatment of infections. (rsc.org)
  • An increase in bacterial mutation rate can promote biofilm formation. (southampton.ac.uk)
  • In this study, the biofilm formation of P. aeruginosa treated with varying concentrations of either 6-shogaol or 6-gingerol was determined through biofilm accumulation assay. (innspub.net)
  • Biofilm formation was inhibited when cells were exposed to nanofibers containing Ciprofloxacin. (sasm.org.za)
  • Identifying molecules able to interfere with biofilm formation is difficult, but further developing these molecules by rationally improving their activity is particularly challenging, as it requires knowledge of the specific protein target that is inhibited. (biosim.pt)
  • Two major thrusts in the last decade have dramatically impacted our understanding of biofilms: the utilization of the confocal laser scanning microscope to characterize biofilm ultrastructure, and an investigation of the genes involved in cell adhesion and biofilm formation. (cdc.gov)
  • Biofilms are notorious for their resistance to environmental stresses, including antimicrobial compounds. (southampton.ac.uk)
  • Treatment of biofilms with nitric oxide also reduced their resistance to antimicrobial compounds. (southampton.ac.uk)
  • Biofilm cultures were treated with NEBB containing enzymes targeted at lipids, proteins, and sugars, also containing the mucolytic compound N-acetyl cysteine, along with antimicrobial extracts from cranberry, berberine, rosemary, and peppermint. (jmb.or.kr)
  • A recent study has demonstrated the antimicrobial efficacy of a novel organic acid compound against common foodborne pathogens and biofilm. (food-safety.com)
  • These findings provide insights into the underlying mechanisms of action of a cerPAC to restrict the virulence of P. aeruginosa and can have implications in the development of alternative approaches to control infections. (nature.com)
  • IMPORTANCE Many infections are polymicrobial and biofilm-associated in nature. (biorxiv.org)
  • Understanding the biological characteristics of biofilms, the cause of most known bacterial infections, is the first step to fight against this silent pandemic and to find effective treatments. (ibecbarcelona.eu)
  • Bacterial infections are a public health problem affecting millions of people worldwid e, and about 80% of them are associated with biofilms , communities formed by different microorganism s' species which co-colonize human tissues and medical devices. (ibecbarcelona.eu)
  • Only with the continuous development and improvement of efficient antibiofilm strategies we can tackle the recurrence and chronicity caused by P. aeruginosa biofilm infections. (ibecbarcelona.eu)
  • P. aeruginosa interacts with many respiratory viruses in chronic infections, including SARS-CoV-2, the causal agent of the COVID-19 pandemic. (ibecbarcelona.eu)
  • Bacterial biofilms are formed by different species that colonize and grow together on human tissues, causing infections in the urinary tract, lung and kidney among others, and on surfaces of medical devices, as joint prostheses , heart valves and pacemakers, dental and breast implants, sutures and catheters. (ibecbarcelona.eu)
  • 3 Bacterial biofilms can cause persistent human infections and can foul the surface of medical devices. (rsc.org)
  • 3,8 Therefore, it is important to develop biomaterials that can control biofilm growth thereby reduce infections. (rsc.org)
  • The cells are often deeply imbedded in biofilms, which makes treatment of the infections extremely difficult. (sasm.org.za)
  • Biofilms have great importance for public health because of their role in certain infectious diseases and importance in a variety of device-related infections. (cdc.gov)
  • [2] [3] The cells within the biofilm produce the EPS components, which are typically a polymeric conglomeration of extracellular polysaccharides , proteins , lipids and DNA . (wikipedia.org)
  • Bacterial cells can colonize surfaces and form biofilms that consist of microbial cells embedded in extracellular polymeric substances (EPS). (rsc.org)
  • This can contribute to biofilm dispersal, and provides a mechanism for the release of extracellular DNA (eDNA) within biofilms. (southampton.ac.uk)
  • Biofilm-associated cells can be differentiated from their suspended counterparts by generation of an extracellular polymeric substance (EPS) matrix, reduced growth rates, and the up- and down- regulation of specific genes. (cdc.gov)
  • A biofilm is an assemblage of surface-associated microbial cells that is enclosed in an extracellular polymeric substance matrix. (cdc.gov)
  • Subpopulations of cells within the biofilm differentiate to perform various activities for motility, matrix production, and sporulation, supporting the overall success of the biofilm. (wikipedia.org)
  • A major cell-associated virulence factor, the Type IV pilus (T4P), is required for epithelial cell adherence and mediates a form of surface translocation termed twitching motility, which is necessary to establish a mature biofilm and actively expand these biofilms. (helmholtz-hzi.de)
  • P. aeruginosa twitching motility-mediated biofilm expansion is a coordinated, multicellular behaviour, allowing cells to rapidly colonize surfaces, including implanted medical devices. (helmholtz-hzi.de)
  • In the current study, we used a global genomics-based random-mutagenesis technique, transposon directed insertion-site sequencing (TraDIS), coupled with a physical segregation approach, to identify all genes implicated in twitching motility-mediated biofilm expansion in P. aeruginosa. (helmholtz-hzi.de)
  • A biofilm comprises any syntrophic consortium of microorganisms in which cells stick to each other and often also to a surface. (wikipedia.org)
  • Biofilms can attach to a surface such as a tooth or rock, and may include a single species or a diverse group of microorganisms. (wikipedia.org)
  • Microorganisms attach to surfaces and develop biofilms. (cdc.gov)
  • Rediscovery of a microbiologic phenomenon, first described by van Leeuwenhoek, that microorganisms attach to and grow universally on exposed surfaces led to studies that revealed surface-associated microorganisms (biofilms) exhibited a distinct phenotype with respect to gene transcription and growth rate. (cdc.gov)
  • These biofilm microorganisms have been shown to elicit specific mechanisms for initial attachment to a surface, development of a community structure and ecosystem, and detachment. (cdc.gov)
  • Van Leeuwenhoek, using his simple microscopes, first observed microorganisms on tooth surfaces and can be credited with the discovery of microbial biofilms. (cdc.gov)
  • 5 ) in 1978 put forth a theory of biofilms that explained the mechanisms whereby microorganisms adhere to living and nonliving materials and the benefits accrued by this ecologic niche. (cdc.gov)
  • Bacterial biofilms are a source of infectious human diseases and are heavily linked to antibiotic resistance. (biosim.pt)
  • Among them, etrasimod (APD334), an investigational drug for the treatment of ulcerative colitis, displayed the best inhibitory activity against S. aureus when growing as free-floating planktonic cells and within biofilms. (helsinki.fi)
  • By electrospinning Ciprofloxacin into a nanofiber scaffold consisting of poly(D,L-lactide) (PDLLA) and poly(ethylene oxide) (PEO), the antibiotic was released within 2 h, killing 99% of P. aeruginosa and 91% of a methicillin-resistant strain of S. aureus in a biofilm. (sasm.org.za)
  • Antibiotic-filled nanofibers may be the answer to the eradication of P. aeruginosa and S. aureus biofilms. (sasm.org.za)
  • Most of the antibiotic was released from the nanofibers within 2 h and almost all cells of P. aeruginosa and S. aureus were killed during this period. (sasm.org.za)
  • AuNPs also showed biofilm inhibition, with the highest of 98% in S. aureus . (dovepress.com)
  • The ability to degrade the biofilm of E. coli , S. aureus , S. enterica , E. faecalis , and P. aeruginosa was evaluated in response to treatment with IDSK. (food-safety.com)
  • Notably, IDSK at a concentration of 0.25 M completely suppresses the growth of P. aeruginosa , E. coli , S. enterica , S. aureus , and E. faecalis after 20 hours of exposure. (food-safety.com)
  • Moreover, approximately 40 percent degradation occurred by exposing the mature biofilm to IDSK at a concentration of 0.25 M. (food-safety.com)
  • Microbial biofilms are resilient, immune-evasive, often antibiotic-resistant health challenges, and increasingly the target for research into novel therapeutic strategies. (jmb.or.kr)
  • Microbial biofilms form on liquid/solid interfaces in nature, such as rocks and clay particles and decaying plant materials. (jmb.or.kr)
  • As the biofilm matures and the community needs change, an individual bacterium may take on new responsibilities. (the-scientist.com)
  • A biofilm usually begins to form when a free-swimming bacterium attaches to a surface. (wikipedia.org)
  • In particular, surface modifications that physically create rational surface topographies have attracted attention in recent years, and have shown to inhibit bacterial attachment and biofilm growth without the use of antimicrobials. (rsc.org)
  • Here we show that E. faecalis inhibits P. aeruginosa growth within biofilms when iron is restricted. (biorxiv.org)
  • We find that E. faecalis ldh1 mutant fails to inhibit P. aeruginosa growth. (biorxiv.org)
  • Together, our results suggest that E. faecalis synergistically inhibit P. aeruginosa growth by decreasing environmental pH and L-lactate-mediated iron chelation. (biorxiv.org)
  • Here, we explore the polymicrobial interactions between commonly co-isolated E. faecalis and P. aeruginosa within biofilms. (biorxiv.org)
  • We find that E. faecalis modulates the microenvironment by exporting lactic acid which further chelates already limited iron, and also lowers the environmental pH to antagonize P. aeruginosa growth in iron-restricted conditions. (biorxiv.org)
  • Conclusion: The antiseptic solutions included in this study had an antibacterial effect against S. mutans, E. faecalis, and P. aeruginosa. (bvsalud.org)
  • Metodologia: Cepas de S. mutans (ATCC 25175), E. faecalis (ATCC 29212) e P. aeruginosa (ATCC 27853) foram inoculadas em 7 mL de brain heart infusion (BHI) e incubadas a 37°C por 24 horas. (bvsalud.org)
  • The biofilm biomass of P. aeruginosa was considerably reduced by 1.56-50mg/L AgNP. (cheric.org)
  • Biofilms are increasingly recognised as the predominant mode of bacterial growth including within medical, engineered, and environmental contexts. (southampton.ac.uk)
  • In vitro studies have shown thatbiofilm-forming P. aeruginosa are significantly less susceptible to antibiotics compared to nonadherent forms 3 , 7 . (ersjournals.com)
  • In this study, the effect of manuka honey on S. pyogenes (M28) was investigated in vitro with planktonic and biofilm cultures using MIC, MBC, microscopy and aggregation efficiency. (microbiologyresearch.org)
  • The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single cells that may float or swim in a liquid medium. (wikipedia.org)
  • Microbes form a biofilm in response to a number of different factors, [9] which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics . (wikipedia.org)
  • In this review, researchers decipher the implication of P . aeruginosa in biofilms and pave the way to find solutions in a near future. (ibecbarcelona.eu)
  • cerPAC reduced the production of QS-regulated virulence determinants and protected D. melanogaster from fatal infection by P. aeruginosa PA14. (nature.com)
  • 4 found that P. aeruginosa PA14 tended to maximum their contact area with the surface, forming a spontaneous cell alignment between periodic nano-pillars with a post pitch of 2.2, 0.9 and 0.7 μm. (rsc.org)
  • Furthermore, monitoring QS signaling gene expression revealed that AHL synthases LasI/RhlI and QS transcriptional regulators LasR/RhlR genes were inhibited and antagonized, respectively, by cerPAC. (nature.com)
  • This tolerance often links biofilms with persistent and chronic infection, and provides ideal conditions for the acquisition or evolution of AMR. (southampton.ac.uk)
  • GAS) is always of clinical significance in wounds where it can initiate infection, destroy skin grafts and persist as a biofilm. (microbiologyresearch.org)
  • One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. (justia.com)
  • Cells in a biofilm are often exposed to sub-lethal concentrations of antibiotics and may develop resistance in a relatively short period. (sasm.org.za)
  • However, biocides commonly used to inhibit biofouling not only increase bacterial resistance, but also damage the chemical structure of the RO membrane due to oxidation. (korea.ac.kr)
  • Recent evidence suggests that P. aeruginosa may actually grow as dense communities of exopolysaccharide-encapsulated biofilms adherent to CF patients' airways 2 - 4 . (ersjournals.com)
  • A microbial biofilm is a community of adherent microbial cellular forms with properties that help protect the microbial community from disruption by physical, chemical, or immunological attack. (jmb.or.kr)
  • extracts inhibited the growth of C. albicans and C. krusei with MIC of 0.03 mg/mL. (bvsalud.org)
  • The biofilm lifestyle involves an increase in bacterial membrane saturated fatty acids. (innspub.net)
  • My research group aims to understand how biofilms develop and disperse and how they respond to environmental stresses including therapeutic compounds. (southampton.ac.uk)
  • Hence, we compared the biofilm reduction of these compounds and visualized their binding interactions to different pathways to hypothesize a possible mechanism of action associated with the biofilm reduction. (innspub.net)
  • The results suggest that targeted nutraceutical support may help disrupt biofilm communities, offering new facets for integrative combinational treatment strategies. (jmb.or.kr)
  • drugs which inhibit growth of fungi are called antifungal drugs . (wikipedia.org)
  • The post-treatment biofilm mass was evaluated by crystal-violet staining, and metabolic activity was measured using the MTT assay. (jmb.or.kr)
  • Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics. (the-scientist.com)
  • These biofilms of aggregating microbes are everywhere: on rocks, bathtubs, and medical devices. (the-scientist.com)
  • The slimy coating on unbrushed teeth is biofilm, and the beneficial microbes on your skin and gut often grow collectively. (the-scientist.com)
  • Biofilms may form on living (biotic) or non-living (abiotic) surfaces and can be prevalent in natural, industrial, and hospital settings. (wikipedia.org)
  • [10] [11] A cell that switches to the biofilm mode of growth undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated . (wikipedia.org)
  • For instance, the cells within a B. subtilis biofilm that are engaged in protease production are randomly determined. (the-scientist.com)
  • Biofilms are an ensemble of microbial cells irreversibly associated with a surface and enclosed in an essentially self-produced matrix. (intechopen.com)
  • Manuka honey permeated 24 h established biofilms of S. pyogenes, resulting in significant cell death and dissociation of cells from the biofilm. (microbiologyresearch.org)
  • An established biofilm structure comprises microbial cells and EPS, has a defined architecture, and provides an optimal environment for the exchange of genetic material between cells. (cdc.gov)
  • By using a specific polysaccharide-stain called Ruthenium red and coupling this with osmium tetroxide fixative, these researchers were also able to show that the matrix material surrounding and enclosing cells in these biofilms was polysaccharide. (cdc.gov)
  • Surface topography designed to achieve spatial segregation has shown promise in delaying bacterial attachment and biofilm growth. (rsc.org)
  • 20 generations, a few days of biofilm growth) within biofilms. (southampton.ac.uk)
  • [5] drugs which inhibit growth of viruses are termed antiviral drugs or antivirals rather than antibiotics. (wikipedia.org)
  • The purpose of the present study was to determine whether the PSB can sample directly from the airway biofilm and, thus, more accurately represent the state of P. aeruginosa in CF patients' lungs. (ersjournals.com)
  • Bactericidal effects were found in both planktonic cultures and biofilms, although higher concentrations of manuka honey were needed to inhibit biofilms. (microbiologyresearch.org)
  • Average biofilm mass and metabolic activity for NEBB-treated biofilms were compared to the average of untreated control cultures. (jmb.or.kr)
  • In this study, 21 diatoms, 7 dinoflagellates, and 4 flagellate species were grown in three different culturing conditions and the corresponding extracts were tested for possible antioxidant, anti-inflammatory, anticancer, anti-diabetes, antibacterial, and anti-biofilm activities. (frontiersin.org)
  • Microbial forms living in biofilms are morphologically and functionally distinct from those of free-floating (planktonic) forms of the same species. (jmb.or.kr)
  • Biofilms are thought to have arisen during primitive Earth as a defense mechanism for prokaryotes, as the conditions at that time were too harsh for their survival. (wikipedia.org)
  • Sublethal concentrations of manuka honey effectively prevented the binding of S. pyogenes to the human tissue protein fibronectin, but did not inhibit binding to fibrinogen. (microbiologyresearch.org)