• However, the mitochondrial oxidative phosphorylation (OXPHOS) pathway in tumor cells has also been implicated in lung cancer metabolism. (spandidos-publications.com)
  • The study of the supramolecular organization of the mitochondrial oxidative phosphorylation system (OXPHOS) in various eukaryotes has led to the accumulation of a considerable amount of data on the composition, stoichiometry, and architecture of its constituent superstructures. (bvsalud.org)
  • Oxidative phosphorylation or electron transport-linked phosphorylation is the metabolic pathway in which cells use enzymes to oxidize nutrients, thereby releasing the chemical energy of molecular oxygen, which is used to produce adenosine triphosphate (ATP). (udemy.com)
  • MTT analysis, PI/Annexin V staining, transwell and metabolic flux assays were performed to examine the effects of C1QBP on proliferation, apoptosis, migration, invasion, and oxidative phosphorylation of HCC cells. (jcancer.org)
  • While there are compelling observational data confirming that individuals who exercise are healthier, the efficacy of aerobic exercise interventions to reduce metabolic risk and improve insulin sensitivity in older people has not been fully elucidated. (biomedcentral.com)
  • Our primary objective is to assess the efficacy of a fully supervised twelve week aerobic exercise intervention in reducing clustered metabolic risk in healthy older adults. (biomedcentral.com)
  • It has been reported that lung cancer cells exhibit upregulated expression of all key glycolytic enzymes [hexokinase 2 (HK2), phosphofructokinase and pyruvate kinase (PK)] ( 13 ), suggesting that the essential enzymes of the aerobic glycolytic pathway have a critical role in the development of lung carcinoma. (spandidos-publications.com)
  • These questions will give you basic idea for Examination Preparation and/or interview on Oxidative Phosphorylation and Nitrogen Metabolism. (udemy.com)
  • CO directly impairs aerobic metabolism in tissues by poisoning the mitochondrial electron-transport chain. (medscape.com)
  • What that means is that bromethalin makes it impossible to maintain aerobic metabolism in the brain. (vin.com)
  • In July 2020, marine biologists reported that aerobic microorganisms (mainly), in "quasi-suspended animation", were found in organically poor sediments, up to 101.5 million years old, 250 feet below the seafloor in the South Pacific Gyre (SPG) ("the deadest spot in the ocean"), and could be the longest-living life forms ever found. (wikipedia.org)
  • Aerobic digestion Anaerobic digestion Fermentation (biochemistry) Aerobic vaginitis Oxygenation (environmental) "aerobe" at Dorland's Medical Dictionary Kroneck PM, Sosa Torres ME, eds. (wikipedia.org)
  • However, facultative anaerobes can live in both aerobic and anaerobic condition. (kenyon.edu)
  • Cellular senescence is controlled by various factors such as cell type and physiological conditions, such as oxidative stress. (dojindo.com)
  • Given the pivotal role played by mitochondria in supplying most energy for physiological activity via oxidative phosphorylation and the environment, herein we sequenced the complete mitogenome of Desis jiaxiangi to investigate the adaptive evolution of the aquatic spider mitogenomes and the evolution of spiders. (biomedcentral.com)
  • Furthermore, PT is necessary to maintain aerobic conditioning of the cardiovascular system. (medscape.com)
  • Mitochondrial DNA plays a vital role in regulating oxidative stress and energy production, and hence may be an important target of selection for flight performance. (nature.com)
  • Tissue hypoxia and oxidative stress account for most of the pernicious effects of CO in the body. (medscape.com)
  • The results showed that although the sulfluramid may cause the production of ROS, its slow action in the organism does not lead to oxidative stress. (springer.com)
  • There is a rise in oxidative stress in workers of leafcutter ants treated with fipronil because SOD significantly increased when compared to the control group. (springer.com)
  • Subsequent studies have revealed that cellular senescence is caused not only by telomere length reduction, but also by external factors such as oncogene activation, oxidative stress, and DNA damage. (dojindo.com)
  • Thus metronidazole does not show any radiosensitizing ability when tested under aerobic conditions [5,9,12,13]. (who.int)
  • While such encouragement seems reasonable given our current knowledge of the benefits of physical activity from observational studies, the evidence base for aerobic exercise interventions in healthy older people ought to be more robust. (biomedcentral.com)
  • Finally, oxidative phosphorylation is a good candidate to play a dual role by decreasing or increasing the risk of lung cancer and glioblastoma in Alzheimer's disease. (nature.com)
  • Given the extensive phenotypic characterization, this study will provide valuable insights into the mechanisms underlying the beneficial effects of aerobic exercise as well as the efficacy, feasibility and safety of such interventions in this age group. (biomedcentral.com)
  • Many previous studies that have assessed aerobic exercise interventions have yielded physiologically informative data but have inherent methodological limitations in terms of assessing the efficacy of these interventions per se. (biomedcentral.com)
  • An aerobic organism or aerobe is an organism that can survive and grow in an oxygenated environment. (wikipedia.org)
  • The attained results, pharmacologically inhibiting either PKA or sAC, indicated that the reversible phosphorylation of the respiratory chain complexes/supercomplexes influenced their assembly state in response to the membrane potential. (bvsalud.org)
  • In particular, strong evidence that aerobic exercise interventions are beneficial in healthy older people is lacking. (biomedcentral.com)
  • The types of exercise incorporated into PT programs for patients with HSP may include strengthening, stretching, and aerobic exercises. (medscape.com)