• HG can be associated with poor maternal, fetal and child outcomes. (nature.com)
  • In the next decade, progress in these areas may improve maternal quality of life and limit the adverse outcomes associated with HG. (nature.com)
  • Although adult infections are typically mild, maternal infection can lead to adverse fetal outcomes. (bvsalud.org)
  • In women with high pre-gestational BMI and twin pregnancy, our aims were to explore the biochemical and hematological parameters and to study the rate of obstetric adverse outcomes. (mdpi.com)
  • The appearance of onfFN and other cellular FNs in cervico-vaginal secretions and maternal blood is associated with adverse pregnancy outcomes. (creative-biolabs.com)
  • Immunological maladaptation in the maternal-fetal interface has accounted for the pathogenesis of adverse pregnancy outcomes, including PE, intrauterine growth restrictions, spontaneous preterm births, and congenital infections [ 1 ]. (biomedcentral.com)
  • With support from the NIH/NHLBI TOPMed program and the PJP grant from the Preeclampsia Foundation, we have developed a large, diverse study population of pregnant individuals and their offspring in the Boston-Colombia Collaborative for Adverse Pregnancy Outcomes (BCC-PREG) cohort. (preeclampsia.org)
  • In recent years, results on the association between serum uric acid (UA) and pregnancy outcomes have been inconsistent, and the association between urea nitrogen (UN) and adverse pregnancy outcomes in normal pregnant women has not been reported. (biomedcentral.com)
  • Thus, we examined the association of UA and UN levels during gestation with the risk of adverse pregnancy outcomes in a relatively large population. (biomedcentral.com)
  • Higher UA and UN levels increased the risk of maternal and fetal outcomes. (biomedcentral.com)
  • Adverse pregnancy outcomes are important public health problems in terms of high mortality and long-term health effects of maternal and newborn babies. (biomedcentral.com)
  • This study assessed the association between serum urea acid and urea nitrogen levels during pregnancy and the risk of adverse pregnancy outcomes in Chinese women. (biomedcentral.com)
  • We found that elevated levels of uric acid and urea nitrogen increased the risk of maternal and infant outcomes. (biomedcentral.com)
  • Thus, accurate identification and management of risk factors for adverse pregnancy outcomes are highly desirable for optimizing care and interventions. (biomedcentral.com)
  • The occurrence and development of adverse pregnancy outcomes are closely related to the status of maternal health during pregnancy, such as levels of serum uric acid (UA) and urea nitrogen (UN). (biomedcentral.com)
  • iNOS plays an important role in poor fetoplacental vascular perfusion and adverse pregnancy outcomes. (medscimonit.com)
  • The authors offer guidance on how to optimize maternal and neonatal health outcomes for women with IBD. (contemporaryobgyn.net)
  • In this article, we will review the basics of IBD and steps to optimize maternal and neonatal outcomes for women with IBD, including preconception counseling, medication management during pregnancy in conjunction with a gastroenterologist, and postpartum care. (contemporaryobgyn.net)
  • Prenatal maternal stress life events are associated with adverse neurodevelopmental outcomes in offspring. (scienmag.com)
  • To identify predictors of adverse pregnancy outcomes (APOs) in patients with inactive or stable active SLE. (nih.gov)
  • The outcomes on the evaluation are provided CD171/L1CAM Proteins web inside the text.six have been also common (Figure 1(a)), primarily in deeper places of your decidua. (nrtisinhibitor.com)
  • Women with Budd Chiari Syndrome (BCS) and/or portal hypertension are at high risk of pregnancy complications and adverse outcomes. (isth.org)
  • Secondary outcomes included maternal, fetal and obstetrical complications. (isth.org)
  • Adverse pregnancy outcomes in women with BCS and portal hypertension are common. (isth.org)
  • Hamulyák EN, Wiegers HMG, van Duuren JR, Middeldorp S, Ganzevoort W. Pregnancy Outcomes in Women with Budd Chiari Syndrome or Portal Hypertension [abstract]. (isth.org)
  • Obesity imparts an ever-present risk for adverse health outcomes for the woman who becomes pregnant and is not of a normal body mass index. (bariatrictimes.com)
  • is strongly associated with preterm birth and adverse neonatal outcomes. (ed.ac.uk)
  • Although the presenting features overlap, they are associated with different maternal and fetal outcomes, biochemical markers, heritability, and clinical features. (yourvdesk.com)
  • There is a growing body of scientific evidence that suggests the potential implication of periodontitis in the causation and progression of various systemic disease and conditions, such as diabetes, cardiovascular disease, pulmonary disease, adverse pregnancy outcomes and cancer. (intechopen.com)
  • This chapter emphasis the relationship between periodontitis and adverse pregnancy outcomes and the underlying mechanisms that link peridontitis to oral carcinogenesis. (intechopen.com)
  • Maintaining maternal health optimizes the success for positive pregnancy outcomes. (apecguidelines.org)
  • Assessment of obstetric risk factors for adverse pregnancy outcomes including previous preterm birth, history of pre-eclampsia/eclampsia, history of gestational diabetes or macrosomic infant, previous C/S, history of IUGR infant. (apecguidelines.org)
  • Adverse perinatal outcomes for the fetus and newborn include intrauterine growth restriction, low birth weight, and stillbirth. (aafp.org)
  • The maternal outcome was studied in terms of type of labour, outcome of pregnancy, mode of delivery, indication of cesarean section, and maternal mortality. (hindawi.com)
  • The foetal complications and outcome parameters were birth weight, Apgar score at the time of birth and at five minutes, need of high dependency unit care, and perinatal mortality. (hindawi.com)
  • This multisystem disorder affects millions of women worldwide and is recognized as an important direct cause of maternal and foetal morbidity and mortality [ 2 ]. (hindawi.com)
  • pre-eclampsia is also associated with adverse fetal mortality and morbidity. (cdc.gov)
  • MgSO 4 reduces the incidence of eclampsia and lowers maternal mortality, and therefore should be considered for women with preeclampsia who are at risk of developing eclampsia. (avpt.it)
  • Since preeclampsia is a leading cause of maternal mortality and preterm birth worldwide, and increases women's future cardiometabolic disease risk 2-4-fold, improved understanding of preeclampsia mechanisms has great potential to positively impact public health. (preeclampsia.org)
  • Intrahepatic cholestasis of pregnancy (ICP) is a condition specific to pregnancy, leading to increased fetal morbidity and mortality. (medscimonit.com)
  • The primary outcome was maternal pregnancy-related mortality and birth of a living fetus. (isth.org)
  • However, in our small cohort, the chance of term live birth of 56% seems too high and maternal mortality too low to consider BCS or portal hypertension an absolute contra-indication. (isth.org)
  • Obesity places a pregnant patient at risk for many serious complications of pregnancy, including maternal and fetal mortality. (bariatrictimes.com)
  • Antenatal glucocorticoids accelerate fetal lung maturation and reduce mortality in preterm babies but can trigger adverse effects on the cardiovascular system. (researchgate.net)
  • Gestational hypoxia is a major contributor to fetal growth restriction (FGR) and perinatal morbidity and mortality and has been closely linked to the activation of the unfolded protein response (UPR) in the placenta. (researchgate.net)
  • It is the second leading cause of maternal mortality worldwide 7 , 8 and may also lead to other serious maternal complications, including stroke, eclampsia, and organ failure. (aafp.org)
  • The USPSTF found adequate evidence that the well-established treatments of preeclampsia result in a substantial benefit for the mother and infant by reducing maternal and perinatal morbidity and mortality. (aafp.org)
  • It's fascinating as a biologist to begin to uncover some of the biological clues to how neurodevelopment is affected during fetal development. (scienmag.com)
  • To investigate association between maternofoetal complications and the amount of proteinuria measured by spot urine protein creatinine ratio in patients with preeclampsia. (hindawi.com)
  • Preeclampsia is a major health problem in maternal health with the prevalence ranging from 1.8% to 16.7% in developing countries [ 1 ]. (hindawi.com)
  • This study was carried out in patients with preeclampsia to estimate the prevalence of maternal and foetal morbidity and to investigate the association between the amount of proteinuria measured by spot UPCR and maternofoetal outcome. (hindawi.com)
  • Preeclampsia is a serious pregnancy disorder marked by elevated blood pressure and the presence of proteins in urine. (cdc.gov)
  • The placental samples 1 cm × 1 cm in size were aseptically obtained from the fetal side and kept in a frozen state (− 70 °C). In all cases of preeclampsia in this study, the patients had blood pressures ≥ 140/90 mmHg, dipstick protein ≥ 1+/4+, or 24-h urine protein ≥ 300 mg/dl. (biomedcentral.com)
  • Previous research has found that these variants in the APOL1 gene increase the risk of developing preeclampsia when present in the fetus and also alter levels of certain proteins in cells when expressed. (preeclampsia.org)
  • A large genetic study of maternal and fetal determinants of preeclampsia, along with global profiling of associated gene transcripts, proteins, and metabolites, to identify the causal biologic pathways altered in pregnancy prior to clinically apparent preeclampsia. (preeclampsia.org)
  • In the coming year, additional molecular profiling (of metabolites and circulating microparticle transcripts and proteins in the maternal blood) will be performed in BCC-PREG to understand the biologic pathways altered prior to the development of preeclampsia. (preeclampsia.org)
  • In pregnancy, elevated maternal IP-10 has been implicated in miscarriage and preeclampsia, but the long-term infant effects of IP-10 exposure in the perinatal period are currently undefined. (globalhealthnewswire.com)
  • Characteristics of maternal vascular malperfusion (MVM) are frequently observed in placentas from pregnancies impacted by preeclampsia, intrauterine growth restriction, preterm labor, and intrauterine fetal demise. (mdpi.com)
  • Important clinical conditions associated with increased risk include a history of eclampsia or preeclampsia (particularly early-onset preeclampsia), previous adverse pregnancy outcome, maternal comorbid conditions (type 1 or 2 diabetes, gestational diabetes, chronic hypertension, renal disease, and autoimmune diseases), and multifetal gestation. (aafp.org)
  • Management strategies for diagnosed preeclampsia may include close fetal and maternal monitoring, antihypertension medications, and magnesium sulfate. (aafp.org)
  • 2 , 3 Although pregnant women can have other hypertensive conditions along with preeclampsia, preeclampsia is defined as new-onset hypertension (or, in patients with existing hypertension, worsening hypertension) occurring after 20 weeks of gestation, combined with either new-onset proteinuria (excess protein in the urine) or other signs or symptoms involving multiple organ systems. (aafp.org)
  • Birth size was strongly correlated with maternal consumption of micronutrient-rich food at all stages of gestation. (who.int)
  • Les mensurations du nouveau-né étaient étroitement corrélées à la consommation maternelle d'aliments riches en micronutriments à toutes les étapes de la gestation. (who.int)
  • METHODS: Fetal nuchal translucency thickness (fetal NT), maternal serum free beta-human chorionic gonadotrophin (free beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A) were measured at 11 weeks 0 days to 13 weeks 6 days of gestation in all women. (who.int)
  • Tumour the fetus via the maternal circulation utero, but when the reactive metab multiplicity rises to a maximum in must have crossed the placenta, and olites formed in maternal tissues are offspring exposed at approximate consequently are generally referred too unstable to circulate in the mater ly 21 days of gestation, a few days to as transplacental carcinogens. (who.int)
  • Factors that cause a low incidence of tumours in offspring after birth, compared contribute to fetal susceptibility to near the end of gestation, in offspring with the incidence and multiplicity of these agents include maternal, pla that were exposed trans placental y. the same types of tumours in their cental, and fetal metabolism, the im This pattern can be seen in the directly exposed mothers. (who.int)
  • 1993). In addition, maternal alcohol consumption during gestation is known to cause fetal growth retardation in humans and laboratory animals (Lin, 1991), an effect persisting for a long period affect parturition (Oyama et al . (scialert.net)
  • b-c) Quantification in the immunoreactivity (pixels/m2) for cytokeratin (CK) and CRIPTO-1 (CR-1) proteins in the maternal-fetal interface in placentas from healthy mothers (gestation week 36) and accreta placentas (b) and of healthy placentas (gestation week 38) and increta and percreta placentas (c). (nrtisinhibitor.com)
  • Although a person is at risk for During gestation, risk factors for obesity include maternal obesity throughout his life, we focus on specific develop- diet, overweight, and smoking. (cdc.gov)
  • Gestation during this period is extremely relevant due to its increasing incidence and maternal effects, such as social isolation and interruption of scholar education. (bvsalud.org)
  • However, the methods for screening the low risk population for other complications of pregnancy such as fetal growth restriction (FGR), pre-eclampsia and stillbirth have remained largely unchanged for the past 20-30 years. (wikipedia.org)
  • The indications for delivery in preterm birth group included preterm labor and preterm premature rupture of the membranes without other maternal or fetal indications. (biomedcentral.com)
  • These findings could provide new insights into how the fetal environment potentially influences not only neurodevelopment, but metabolism and immunologic functions as well. (scienmag.com)
  • Nutritions taken during pregnancy can have significant and lasting effects on maternal and newborn health. (beneficialplant.com)
  • Cannabis consumption by pregnant women continues to increase worldwide, raising concerns about adverse effects on fetal growth and deleterious impacts on the newborn, in connection with evidence of placental transfer of cannabis compound. (biomedcentral.com)
  • No vaccine-related maternal or fetal/newborn side effects have been observed with the vaccine, as per the FDA. (ijcp.in)
  • In this context, we aimed to determine whether cannabis exposure has the potential to directly impact the human fetal testis. (biomedcentral.com)
  • We determined the expression of components of the ECS in the human fetal testis from 6 to 17 developmental weeks and assessed the direct effects of phytocannabinoids Δ9-trans-tetrahydrocannabinol (THC) and cannabidiol (CBD) on the testis morphology and cell functions ex vivo. (biomedcentral.com)
  • We demonstrate the presence in the human fetal testis of two key endocannabinoids, 2-arachidonylglycerol (2-AG) and to a lower level anandamide (AEA), as well as a range of enzymes and receptors for the ECS. (biomedcentral.com)
  • Our study is the first to evidence the presence of the ECS in the human fetal testis and to highlight the potential adverse effect of cannabis consumption by pregnant women onto the development of the male gonad. (biomedcentral.com)
  • AU TGA pregnancy category D: Drugs which have caused, are suspected to have caused or may be expected to cause, an increased incidence of human fetal malformations or irreversible damage. (drugs.com)
  • I think it's a really interesting approach to look at DNA methylation," said Lydia Shook, an obstetrician-gynecologist at Massachusetts General Hospital who specializes in maternal-fetal medicine. (genomeweb.com)
  • Oncofetal fibronectin (onfFN) is an extracellular matrix (ECM) protein synthesized by tumours and fetal tissue including placenta. (creative-biolabs.com)
  • abilities are intensified to specific maternal and environ- mental exposures that can lead to obesity (2). (cdc.gov)
  • glucocorticoids, protein restrictions, and maternal diet and obesity. (cdc.gov)
  • For example, as cited by Flick and Artel,[11] traditional thought has been that even in the patient population with obesity, maternal weight gain should be "net positive" to reflect the weight of the products of conception and increased uterine size. (bariatrictimes.com)
  • The findings mean that even at the extremes of reproductive age (adolescent and advanced maternal age), the constitution of colostrum in casein and protein was constant, in contrast to previous data regarding other factors such as maternal diet, obesity, diabetes that influence colostrum composition. (bvsalud.org)
  • which may render the genetic mate doses of NDMA is the kidney, but a Transplacental carcinogenesis rial of fetal cells highly accessible to much lower incidence of tumours is stu dies with ENU in nonhuman pri carcinogens. (who.int)
  • Maternal Age Risk factors for complications during pregnancy include Preexisting maternal disorders Physical and social characteristics (eg, age) Problems in previous pregnancies (eg, a previous history. (msdmanuals.com)
  • By maintaining maternal euglycemia, such pregnancies were able to continue into term and resulted in a reduction in complications related to prematurity, including respiratory distress syndrome. (beneficialplant.com)
  • The quality of fetal diaphragm movements is affected in pregnancies complicated with GDM and PGDM. (biomedcentral.com)
  • Recent studies on adverse pregnancy conditions show differential adaptive responses in pregnancies carrying male or female fetuses. (researchgate.net)
  • ENU during the final week of gestat the rapidly changing patterns of gene In both the fetus and the pregnant ion is approximately 50 times that of expression in fetal target tissues, female rat, the target organ for single the mother. (who.int)
  • This study examined the quality of fetal diaphragmatic contractions in pregnant women complicated with GDM and PGDM. (biomedcentral.com)
  • Feeding low-protein diets to pregnant rats produces a increased more than in children not exposed to tobacco in broad spectrum of disorders in their offspring (7): hyper- utero. (cdc.gov)
  • Risk Summary: Based on findings in animal studies and the mechanism of action, this drug may cause fetal harm when administered to a pregnant woman. (drugs.com)
  • This study also importantly provides additional reasons to encourage pregnant women to pursue vaccination against COVID-19 to avoid any long-term adverse consequences for their infant. (globalhealthnewswire.com)
  • If associated with pathophysiological changes that occur during pregnancy , this may result in epigenetic changes with insufficient or excessive nutritional intake, short- and long-term adverse effects on the fetus. (beneficialplant.com)
  • In a cohort study involving approximately 250,000 women in China, maternal intake of 0.4 mg of folic acid was shown to reduce the risk of NTD in the fetus by 85% in high-prevalence regions and 40% in low-prevalence regions.The use of folic acid antagonist drugs, which cause inhibition of the dihydrofolate reductase enzyme, increases the frequency of CHD. (beneficialplant.com)
  • Maternal alcohol consumption affects different organs and systems of the developing fetus (Dencker and Eriksson, 1998). (scialert.net)
  • In cases of extreme fetal hydrops, the mother may be at risk for maternal mirror syndrome, which is when the mother's condition mimics that of the sick fetus. (ucsfbenioffchildrens.org)
  • Maternal PON1 status (PON1 activity levels, the most important measurement, and functional Q192R phenotype) modulates the detrimental effects of exposure to the OP chlorpyrifos oxon on fetal brain gene expression and biomarkers of exposure. (cdc.gov)
  • The points in the figures showing no-observed-adverse-effect levels (NOAELs) or lowest-observed-adverse-effect levels (LOAELs) reflect the actual doses (levels of exposure) used in the studies. (cdc.gov)
  • Public health officials and others concerned with appropriate actions to take at hazardous waste sites may want information on levels of exposure associated with more subtle effects in humans or animals (LOAELs) or exposure levels below which no adverse effects (NOAELs) have been observed. (cdc.gov)
  • An MRL is defined as an estimate of daily human exposure to a substance that is likely to be without an appreciable risk of adverse effects (noncarcinogenic) over a specified duration of exposure. (cdc.gov)
  • In the USA, while fetal exposure to tobacco decreases, cannabis use during pregnancy rises along with the enhanced perception that there are no risks with cannabis consumption during pregnancy [ 2 ]. (biomedcentral.com)
  • In humans, low protein intake by women in late but intrauterine exposure was (20). (cdc.gov)
  • Perinatal exposure to these cytokines has also been associated with altered fetal development. (globalhealthnewswire.com)
  • Over recent years, we have witnessed a great improvement in population-based screening methods for fetal abnormalities as a result of technological developments in ultrasound, biochemical screening and molecular genetics. (wikipedia.org)
  • Improved methods using mass spectrometry to monitor OP-adducted biomarker proteins are needed and will be extremely helpful in early life biomonitoring, while measurement of PON1 status as a biomarker of susceptibility will help identify mothers and children highly sensitive to OPs. (cdc.gov)
  • Recent advances in the genetic study of NVP and HG suggest a placental component to the aetiology by implicating common variants in genes encoding placental proteins (namely GDF15 and IGFBP7 ) and hormone receptors (namely GFRAL and PGR ). (nature.com)
  • Because DNA methylation signatures are heritable and exist in almost all cell types, they afford researchers "a better genome-wide assessment" compared with studying individual genes or proteins and the opportunity to be studied in easily obtained samples, he added, such as the cheek buccal cells used in this study. (genomeweb.com)
  • Transcriptomic analysis on 72 h-exposed fetal testis explants revealed 187 differentially expressed genes (DEGs), including genes involved in steroid synthesis and toxic substance response. (biomedcentral.com)
  • This drug was associated with decreased fetal weights, external malformations, and skeletal variations in animal studies. (drugs.com)
  • In animal reproduction studies, administration during organogenesis resulted in decreased fetal weight and congenital malformations at maternal exposures 12 times higher than recommended human dose. (drugs.com)
  • We found five specific locations of DNA methylation with three different maternal stressors during pregnancy," she says. (scienmag.com)
  • If maternal diabetes is longstanding or associated with known microvascular disease, obtain a baseline maternal electrocardiogram (ECG) and echocardiogram. (medscape.com)
  • We excluded patients with chronic hypertension, diabetes mellitus, preexisting renal disease, urinary tract infection, intrauterine foetal death, multiple-foetus gestations, premature rupture of membrane, and postterm pregnancy from our study. (hindawi.com)
  • The prolonged duration of diabetes may have additional adverse effects on diaphragm morphology and its function. (biomedcentral.com)
  • As shown in both animals and humans, insufficient maternal zinc intake leads to a decrease in circulating zinc levels, which can adversely affect fetal neural tube development. (beneficialplant.com)
  • The human leukocyte antigen (HLA) system is a major histocompatibility complex (MHC) protein in humans. (biomedcentral.com)
  • Ultrasonography to monitor fetal growth is done at 28 weeks and every 4 weeks thereafter. (msdmanuals.com)
  • Therefore, monitoring maternal uric acid and urea nitrogen biochemical parameters during pregnancy is necessary to optimize nursing and intervention. (biomedcentral.com)
  • Main outcome measures Nitric oxide, high-sensitive C reactive protein (hs-CRP), uric acid, blood lipids and protein levels were analysed in maternal and cord blood. (bmj.com)
  • Maternofoetal complications and outcome correlate with maternal spot UPCR. (hindawi.com)
  • MAIN OUTCOME MEASURES: Fetal NT, maternal serum free beta-hCG, PAPP-A and cotinine measurements. (who.int)
  • What you're seeing biologically at the beginning of fetal development you might not see the outcome of until later on during a child's development. (scienmag.com)
  • Our understanding of fetal cardiovascular physiology has markedly increased in the last 50 years, with the introduction of suitable animal models. (researchgate.net)
  • Estetrol is only 46% to 50% bound by plasma proteins, while drospirenone is 96% bound. (uspharmacist.com)
  • Because it is more than 84% bound to plasma proteins, the amount in milk is likely to be low. (drugs.com)
  • The thickness of fetal diaphragm (DT), diaphragmatic excursion (DE), diaphragm thickening fraction (DTF) and costodiaphragmatic angle (CDA) was measured and recorded by ultrasound and examined on the video frame during the inspiration and expiration phases of respiration. (biomedcentral.com)
  • The thickness of fetal diaphragm, movements and function were evaluated via using ultrasound. (biomedcentral.com)
  • c), J) Adverse manage on the immunohistochemistry reactions in which the respective key antibody has been omitted. (nrtisinhibitor.com)
  • Studies have demonstrated the appearance of "new" adverse reactions for many NMEs within several years of their first becoming available. (uspharmacist.com)
  • Some of these drugs may eventually acquire at least one black box warning for serious adverse drug reactions or be withdrawn from the market for safety reasons that were not recognized at the time of approval. (uspharmacist.com)
  • Available data also do not indicate whether Tdap-induced transplacental maternal antibodies provide early protection against pertussis to infants or interfere with an infant's immune responses to routinely administered pediatric vaccines. (cdc.gov)
  • The mother may develop symptoms similar to pre-eclampsia, such as vomiting, hypertension, swollen feet and hands, proteinuria (protein in the urine) and fluid in the lungs. (ucsfbenioffchildrens.org)
  • The USPSTF found adequate evidence that testing for protein in the urine with a dipstick test has low diagnostic accuracy for detecting proteinuria in pregnancy. (aafp.org)
  • Maternal serum level of Delta-like homolog 1 (DLK1), protein involved in the regulation of maternal metabolic state and fetal growth in mice, differentiates constitutionally small and pathologically small (or fetal growth restricted) human fetuses. (wikipedia.org)
  • Delayed growth is evaluated with multivessel Doppler testing by a maternal-fetal medicine specialist. (msdmanuals.com)
  • Zinc is essential for normal fetal growth and development and is a component of more than 200 enzymes involved in the formation and release of various proteins, hormones, and neuropeptides. (beneficialplant.com)
  • Which growth criteria better predict fetal programming? (bmj.com)
  • The authors suggest that combined with maternal biochemistry, these growth criteria can be used to screen for adverse fetal programming . (bmj.com)
  • In turn, chronic fetal hypoxaemia promotes oxidative stress, and maternal antioxidant therapy in animal models of hypoxic pregnancy has proven to be protective with regards to fetal growth and cardiovascula. (researchgate.net)
  • Epidemiologic studies suggest that children from mothers with lower PON1 status who were in contact with OPs during pregnancy tend to show smaller head circumference at birth and adverse effects in cognitive function during childhood. (cdc.gov)
  • Monitor patients periodically for signs of adverse effects on the nasal mucosa. (nih.gov)
  • The effects of gender and alcohol consumption on serum enzymes, protein and bilirubin in heavy, moderate and non-drinkers were investigated. (scialert.net)
  • Due to these adverse effects, some functional disorders of these organs occur frequently. (scialert.net)
  • The most commonly reported adverse effects in clinical trials have been local pain and redness at the site of injection. (ijcp.in)
  • These drugs may also have adverse pharmacological effects. (drugs.com)
  • Typically, there are low rates of viral transmission to an infant after a COVID-19 infection during pregnancy, and no other apparent adverse effects on the infant at birth. (globalhealthnewswire.com)
  • The results of this study indicate that there are unidentified effects of COVID-19 infection during pregnancy on infants, specifically the evidence of in-utero inflammation persisting weeks to months after initial maternal infection. (globalhealthnewswire.com)
  • These results will soon be submitted for publication and provide additional evidence that vaccination rather than COVID-19 infection during pregnancy provides protection for the infant against any adverse effects. (globalhealthnewswire.com)
  • However, SCTs that are made up of mostly solid tissue and have a lot of blood flow can have adverse effects. (ucsfbenioffchildrens.org)
  • Pre-eclampsia has an immense adverse impact on maternal and perinatal health, especially in the developing world. (avpt.it)
  • In this new study however, researchers discovered elevated levels of markers, interleukin (IL)-6 and interferon gamma-induced protein (IP)-10, well-characterized inflammatory mediators central in the COVID-19 cytokine response, in both mothers and infants who experienced a COVID-19 infection during pregnancy. (globalhealthnewswire.com)
  • Marker IL-8 was also uniquely elevated in infants following maternal COVID-19 infection. (globalhealthnewswire.com)
  • Chronic fetal hypoxaemia is a common pregnancy complication that increases the risk of infants experiencing respiratory complications at birth. (researchgate.net)
  • It impacts approximately 2% to 4% of expectant mothers worldwide, resulting in approximately 46,000 maternal fatalities and roughly 500,000 deaths of both fetuses and newborns annually. (cdc.gov)
  • Maternal weight and height, food frequency intake during pregnancy and haemoglobin levels were recorded for 594, 234 and 246 of the mothers respectively. (who.int)
  • Statistically significant negative correlations were found between maternal haemoglobin levels and birth size. (who.int)
  • Women were grouped according to smoking status, confirmed by maternal serum cotinine measurements, and analyte levels between groups were compared. (who.int)
  • RESULTS: Compared with nonsmoking women, fetal NT was significantly increased and free beta-hCG and PAPP-A levels were significantly decreased in both cigarette and sheesha smokers. (who.int)
  • High levels of protein in your urine. (avpt.it)
  • The study aims to design a special assay using these cell lines to measure changes in protein levels after treatment with different compounds. (preeclampsia.org)
  • Serum protein, albumin and bilirubin levels were significantly different in both male and female heavy and moderate drinkers. (scialert.net)
  • Serum protein, albumin and bilirubin levels were impaired by alcohol consumption in both males and females and may provide additional information in the diagnosis and management of alcoholism. (scialert.net)
  • Enzyme-linked immunosorbent assays were used to investigate maternal plasma iNOS levels. (medscimonit.com)
  • This was the first study to suggest that smoking tension and vascular defects (8,9), altered fetal pancreatic during pregnancy is linked to adverse changes in the lipo- development and structure (10), altered glucose tolerance protein levels of children (19). (cdc.gov)
  • In a study published in the Journal of Alzheimer's Disease , researchers revealed that Alzheimer's disease is caused by a decline in levels of a protein called amyloid-beta. (ijcp.in)
  • These levels decrease because the normal protein, under situations of biological, metabolic or infectious stress, transforms into abnormal amyloid plaques. (ijcp.in)
  • The child should undergo yearly blood tests for elevated alpha feto-protein (AFP) levels, and should be followed by an oncologist (cancer specialist) and pediatric surgeon in early childhood. (ucsfbenioffchildrens.org)
  • Maternal flares, higher disease activity, and smaller increases in C3 level later in pregnancy also predicted APOs. (nih.gov)
  • It shows that while maternal age consistently increases the risk of autism, the father's age only contributes an increased risk when the father is older and the mother is under 30 years old. (livescience.com)
  • This study in Egypt investigated the influence of selected maternal factors on neonatal birth size. (who.int)
  • A significant positive correlation between maternal anthropometric variables with neonatal birth dimensions was observed and the effect was more evident in girls than boys for BMI and head circumference. (who.int)
  • Surprisingly, many of the epigenetic shifts that were observed in the mother were also transmitted to the premature female babies," said Skinner, based on a comparison of maternal DMRs with 136 DMRs of female children. (genomeweb.com)
  • New research out of the University of Cincinnati examines the impact that maternal stress during pregnancy has on the neurodevelopment of babies. (scienmag.com)
  • These babies may be candidates for fetal intervention. (ucsfbenioffchildrens.org)
  • CONCLUSIONS: Cigarette and sheesha smoking significantly affect first-trimester markers of Down syndrome (fetal NT, free beta-hCG and PAPP-A). Correction for this effect in women who smoke might improve the effectiveness of first-trimester screening for Down syndrome in these women. (who.int)
  • Whole blood was taken via puncture of the cubical vein and serum protein, albumin, total and direct bilirubin concentrations were determined using Synchron CX 5 autoanalyzer. (scialert.net)
  • In this prospective cohort study, a maternal blood sample and an infant blood sample were collected from 31 COVID and 29 control dyads at the time of delivery and analyzed with a panel of 13 cytokines, which are soluble markers of immune responses. (globalhealthnewswire.com)
  • Fetuses with large tumors that have a great deal of blood flow must be followed closely to watch for the development of heart failure, which can lead to fetal death. (ucsfbenioffchildrens.org)
  • Severe zinc deficiency is embryotoxic and teratogenic and can cause fatal fetal developmental and structural anomalies. (beneficialplant.com)