• Because ES cells are cultured from the embryoblast 4-5 days after fertilization, harvesting them is most often done from donated embryos from in vitro fertilization (IVF) clinics. (wikipedia.org)
  • Belgium bans reproductive cloning but allows therapeutic cloning of embryos. (wikipedia.org)
  • France prohibits reproductive cloning and embryo creation for research purposes, but enacted laws (with a sunset provision expiring in 2009) to allow scientists to conduct stem cell research on imported a large amount of embryos from in vitro fertilization treatments. (wikipedia.org)
  • Italy has a 2004 law that forbids all sperm or egg donations and the freezing of embryos, but allows, in effect, using existing stem cell lines that have been imported. (wikipedia.org)
  • In 2003, Spain's laws state that embryos left over from IVF and donated by the couple that created them can be used in research, including ES cell research, if they have been frozen for more than five years. (wikipedia.org)
  • Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)
  • To create embryos with the intention of destroying them, even with the intention of helping the sick, is completely incompatible with human dignity, because it makes the existence of a human being at the embryonic stage nothing more than a means to be used and destroyed. (archdiocese-no.org)
  • The problem is that stem cells are currently sourced from human embryos, either from aborted fetuses (as in this case), or from blastocysts created by artificial insemination and grown in vitro specifically for the purpose. (blogspot.com)
  • But stem cells from embryos/blastocycts either aborted or cultured are IMO unethical to use. (blogspot.com)
  • Depending on the source, stem cells can be classified into two broad categories i.e. embryonic stem cells that are derived from embryos and non-embryonic stem cells that are derived from adult and fetal tissues. (benthamscience.com)
  • Under such circumstances, the idea of "therapeutic cloning" was proposed, indicating the generation of ESCs from SCNT embryos for therapeutic purpose. (benthamscience.com)
  • However, the derivation of human NT-ESCs goes with the destruction of clone embryos, leading to fierce ethical disputes. (benthamscience.com)
  • In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
  • They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
  • Moreover, the field is only inching forward scientifically as it is proving very hard to harness cells meant to create differentiated tissues in gestating embryos and fetuses. (nationalrighttolifenews.org)
  • These scientists destroyed the embryos and derived stem cell lines. (nationalrighttolifenews.org)
  • Most embryos…formed one or two pronuclei at the time of removal from TSA, whereas a slightly higher portion of embryos cleaved…suggesting that some SCNT embryos did not exhibit visible pronuclei at the time of examination… Most cleaved embryos developed to the eight-cell stage…but few progressed to compact morula…and blastocyst. (nationalrighttolifenews.org)
  • Activation of embryonic genes and transcription from the transplanted somatic cell nucleus are required for development of SCNT embryos beyond the eight-cell stage…Therefore, these results are consistent with the premise that our modified SCNT protocol supports reprogramming of human somatic cells to the embryonic state. (nationalrighttolifenews.org)
  • A story in News.Com.Au-which runs stories from several Australian newspapers celebrates the cloning breakthrough because it means no embryos are used in the process! (nationalrighttolifenews.org)
  • But it is an important step in research because it doesn't require the use of embryos in creating the type of stem cell capable of transforming into any other type of cell in the body. (nationalrighttolifenews.org)
  • The Los Angeles Times has waded in to the junk biology game, assuring us that no embryos are threatened in human cloning-WHEN THE WHOLE POINT OF HUMAN CLONING IS TO CREATE AN EMBRYO! (nationalrighttolifenews.org)
  • The hybrid cells carrying four sets of chromosomes (instead of the usual two) behaved as stem cells when injected into mouse embryos. (i-sis.org.uk)
  • Three days ago the science journal Nature reported that mouse tissue cells in the US and Japan were turned into embryonic-type stem cells without the use of eggs or embryos. (freerepublic.com)
  • Despite the many advances in adult stem cell research, the federal and Victorian parliaments have already passed bad legislation legitimising the destruction of human embryos. (freerepublic.com)
  • Some also hide behind the fallacious argument that dissecting human embryos must not be seen as a loss of embryonic life. (catholicphilly.com)
  • Moreover, because embryonic stem cells can be rejected as foreign tissue by patients' bodies, are very unstable and are difficult to develop into just one cell type at a time, great numbers of viable human embryos with different genetic profiles may be needed to continue this line of research. (catholicphilly.com)
  • The mass production of human embryos also poses important ethical challenges, including the cloning of human embryos in laboratories for research purposes and the probable exploitation of women to obtain the eggs needed for such production. (catholicphilly.com)
  • Citizens disagree about whether we should destroy human embryos for their stem cells-and if so, which embryos, with whose money, under what regulatory guidelines. (eppc.org)
  • The holy grail of regenerative medicine-whatever one's ethical beliefs about destroying embryos-is to "reprogram" regular cells from one's own body so that individuals can be the source of their own rejection-proof therapies. (eppc.org)
  • That is to say, we risk turning developed cells into developing embryos, and thus risk engaging in the very activities of embryo destruction and human cloning that we seek to avoid. (eppc.org)
  • But we need to proceed carefully, recognizing that we are gaining new powers over human origins even when we do not use human embryos, and recognizing the danger of blurring the line between cellular parts and embryonic wholes. (eppc.org)
  • Far more controversial-and for good reason-are stem cells derived from destroyed human embryos. (eppc.org)
  • Researchers there are working on technology that induces human skin cells to change into the kind of stem cells that have been created by embryos. (cbc.ca)
  • Some argue that the possibility of mimicking stem cells without acquiring them from embryos, side-steps that moral dilemma. (cbc.ca)
  • Embryonic stem cells come from embryos, embryonic germ cells from testes, and adult stem cells can come from bone marrow. (cbc.ca)
  • This new method of generating stem cells does not require embryos as starting points and could be used to generate cells from many adult tissues, such as a patient's own skin cells,' said principal author Andras Nagy, senior investigator at Mount Sinai's Samuel Lunenfeld Research Institute. (cbc.ca)
  • President Bush, saying he wanted to "proceed with great care," announced in a national address on August 9 that he would allow federal funding of an existing 60 stem-cell lines but would not permit tax dollars to pay for the destruction of any additional human embryos. (christianitytoday.com)
  • The rule circumvented a 1995 congressional ban on using federal money for biomedical research on embryos outside the womb by allowing researchers to use stem cells extracted by a third party. (christianitytoday.com)
  • The groups argue that rather than waste embryos that will be destroyed along with their stem cells, researchers should use them to help save those whose lives are being cut short by disease. (christianitytoday.com)
  • Indeed, some observers believe the demand for stem cells is dangerously close to spawning a huge commercial industry around the sale of and experimentation on human embryos. (christianitytoday.com)
  • Already, news that Advanced Cell Technology-a Massachusetts-based, privately held biotech company-and Virginia Medical School's Jones Institute had created or planned to create human embryos for the sole purpose of extracting their stem cells has troubled those on both sides of the debate. (christianitytoday.com)
  • A year ago, we showed that you could do it with cells from embryos," says Wilmut. (newscientist.com)
  • Particularly valuable animals could be cloned from adult cells without the uncertainties of crossing them with other animals or tinkering with embryos. (newscientist.com)
  • More importantly, biotechnologists will for the first time be able to manipulate the genes of cells from farm animals directly before growing them into embryos. (newscientist.com)
  • But scientists have not managed to isolate such cells from farm animals, and must rely instead on injecting genes randomly into early embryos. (newscientist.com)
  • Among the real and knotty ethical questions are these: Should human embryos be created expressly to be used for stem cell extraction? (prospect.org)
  • Should women be paid to donate eggs or fertilized embryos to stem cell labs? (prospect.org)
  • He decreed that stem cell colonies produced before Aug. 9, 2001, could continue to receive federal funding for research purposes but no federal money could go to develop new stem cells from embryos. (prospect.org)
  • Embryonic stem cell research "uses special cells found in three-to-five day old human embryos to seek cures for a host of chronic disease" (PRC). (ipl.org)
  • Leeb, M. & Wutz, A. Derivation of haploid embryonic stem cells from mouse embryos. (nature.com)
  • Scientists have applied somatic cell nuclear transfer to clone human and mammalian embryos as a means to produce stem cells for laboratory and medical use. (asu.edu)
  • Embryonic stem cells are a particular type of stem cell derived from embryos. (asu.edu)
  • First, while stem-cell experimentation could involve the creation of embryos with the express purpose of destroying them, this is not the only means available for obtaining embryos. (jewishvaluesonline.org)
  • Thus, there is broad halakhic (Jewish legal) agreement that stem cell research is permitted on "excess" embryos. (jewishvaluesonline.org)
  • Most (but not all) authorities would forbid the creation of embryos with the express purpose of killing them in the pursuit of stem cell research. (jewishvaluesonline.org)
  • The controversy over stem cell research is focused specifically on the use of stem cells taken from embryos. (jewishvaluesonline.org)
  • The environmental group argued that Brüstle's work was "contrary to public order" because embryos were destroyed to gather the stem cells used. (ox.ac.uk)
  • The judgment effectively supports the Greenpeace view and imposes a ban on patenting work that uses embryonic stem cells on the grounds that it represents an immoral "industrial" use of human embryos. (ox.ac.uk)
  • Stem cells from embryos may provide the holy grail of medicine. (ox.ac.uk)
  • Stem cells from embryos are very special building blocks. (ox.ac.uk)
  • Instead of becoming "biowaste" these embryos could be used to produce embryonic stem cells. (ox.ac.uk)
  • It would require that 25 percent of these funds be diverted for research on stem cells that are not derived from embryos or unborn fetuses. (mbcpathway.com)
  • We hope we can encourage ethical stem cell research," said Bartle, noting that many popular proposals involve the use of embryonic stem cells, a human cloning technique that destroys human embryos. (mbcpathway.com)
  • In a 2012 letter to Children of God for Life, PepsiCo stated that "Senomyx does not use HEK cells or any other tissues or cell lines derived from human embryos or babies for research performed on behalf of PepsiCo. (hli.org)
  • The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)
  • Unicellular for those cells that are derived from human organisms are primed to replicate (clone) pre-embryos, which seem to have a high themselves by nature. (who.int)
  • Sweden forbids reproductive cloning, but allows therapeutic cloning and authorized a stem cell bank. (wikipedia.org)
  • From the ethical point of view, so-called therapeutic cloning is even more serious. (archdiocese-no.org)
  • Therapeutic Use of Cloning: Osmangazi Tu. (yildiz.edu.tr)
  • There are important problems in the therapeutic use of cloning which increase with the more advanced differentiation of somatic cells. (yildiz.edu.tr)
  • Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
  • What's the difference between therapeutic cloning and reproductive cloning? (wisdomanswer.com)
  • Therapeutic cloning produces embryonic stem cells for experiments aimed at creating tissues to replace injured or diseased tissues. (wisdomanswer.com)
  • Gene cloning, also known as DNA cloning, is a very different process from reproductive and therapeutic cloning. (wisdomanswer.com)
  • Kuldip S. Sidhu , " Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside ", Bentham Science Publishers (2012). (benthamscience.com)
  • Embryonic stem cells (ESCs) can grow infinitely and give rise to all types of cells in human body, thus of tremendous therapeutic potentials for a variety of diseases, such as Parkinson's disease, spinal cord injury, and diabetes. (benthamscience.com)
  • The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)
  • Although attempts have not yet been made to create a therapeutic transplant from embryonic stem cells, the methods have been developed to allow the creation of functional, mature cells using human cell cloning technology. (news-medical.net)
  • Britain s House of Lords final approval of therapeutic human cloning and embryonic stem cells research has intensified the battle for ascendancy between adult and embryonic stem cells. (i-sis.org.uk)
  • There is also peer-reviewed evidence of the therapeutic benefit to patients who have received an adult stem cell treatment for 72 disease and conditions. (freerepublic.com)
  • In particular, scientific developments in areas such as iPS cells open new possibilities of research and, at mid term, of therapeutic applications, but they also bring new ethical challenges and problems requiring further reflection and debate. (lifeissues.net)
  • Therapeutic cloning uses has some deficiency regarding the use of stem cells? (curtisrobertmacdonald.com)
  • But adult stem cells also raise some interesting ethical dilemmas alongside their great therapeutic promise. (eppc.org)
  • His announcement a week earlier of a supposed breakthrough in human cloning nearly stampeded the Senate into banning cloning even for therapeutic purposes. (prospect.org)
  • He explained that the early embryonic cells that his laboratory tries to turn into specialized tissue for therapeutic purposes hadn't even ''individuated'' yet. (prospect.org)
  • At the same time, there are indeed myriad ethical questions raised by the effort to develop therapeutic applications of stem cell cloning. (prospect.org)
  • However, there are a number of factors limiting the procurement of organs and accordingly, therapeutic cloning that perhaps can yield still better results needs to be considered as an alternative. (scialert.net)
  • Embryonic cell lines and autologous embryonic stem cells generated through therapeutic cloning have also been proposed as promising candidates for future therapies. (techxplore.com)
  • Altogether, our results demonstrate the protective role of SOD1 against oxidative stress and DNA damage in PPM1D-mutant leukemia cells and highlight a new potential therapeutic strategy against PPM1D-mutant cancers. (bvsalud.org)
  • 5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
  • Therapeutic cloning possesses enormous potential for revolutionizing medical and thera- peutic techniques. (who.int)
  • This is therapeutic cloning. (who.int)
  • This cell then has therapeutic cloning: the global the capacity to divide and grow into an exact replica of the original from whom the debate somatic cell was taken. (who.int)
  • The primary legislation in South Africa that deals with embryo research is the Human Tissue Act, which is set to be replaced by Chapter 8 of the National Health Act. (wikipedia.org)
  • It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
  • But it is perhaps not auspicious to quote him for purposes of the scientific debates on human cloning, because Ramsey agreed with and supported the scientific myth of the "pre-embryo" 47 made famous by Jesuit Richard McCormick and frog embryologist Clifford Grobstein. (lifeissues.net)
  • Perhaps Ramsey would give other extraordinarily powerful arguments as to why human cloning is unethical, but he obviously would not be able to base it on his unscientific "pre-embryo" position. (lifeissues.net)
  • Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
  • Dr. Shinya Yamanaka of Japan and others have turned adult skin cells into human embryonic stem cells, without using an embryo. (nationalrighttolifenews.org)
  • creates a cloned embryo. (nationalrighttolifenews.org)
  • A cloned embryo-like a natural embryo-is an individual organism, a member of its (in this case, human) species. (nationalrighttolifenews.org)
  • After that, the question becomes not whether to clone, but what to do with the embryo that was created through the cloning process. (nationalrighttolifenews.org)
  • increased public sensitivity and awareness together with the development of national regulations of governance of human cloning and embryo research in general. (lifeissues.net)
  • 3. National regulations of governance of human cloning and embryo research in general adopted so far confirm the convergence of views of the refusal to adopt legislation or guidelines permitting reproductive cloning , while they still show variations on the legitimacy of human cloning carried out as part of research agendas. (lifeissues.net)
  • Embryonic stem cell research, however, poses serious ethical concerns because it requires destroying an embryo in order to obtain the cells. (catholicphilly.com)
  • … "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)
  • … "human clone" means an embryo that, as a result of the manipulation of human reproductive material or an in vitro embryo, contains a diploid set of chromosomes obtained from a single - living or deceased - human being, fetus, or embryo. (hinxtongroup.org)
  • Researchers create embryonic stem cells without embryo. (curtisrobertmacdonald.com)
  • Research advocates attack President Bush for "banning stem cell research," while pro-life advocates lament a Republican administration and Congress that have banned nothing-not embryo destruction, not human cloning, not fetal farming, not genetic engineering. (eppc.org)
  • Before leaving office, President Clinton sought to get around the existing law without actually changing it, by funding research on embryonic stem cells so long as the actual embryo destruction was paid for with private dollars. (eppc.org)
  • Bush promised in January to review a Clinton administration rule that allowed federal funding for researchers experimenting on embryo cells from fertility clinics. (christianitytoday.com)
  • Under the rule, a third party could destroy the embryo by taking it apart and preserving the remaining living stem cells for research. (christianitytoday.com)
  • They produced idential lambs called Megan and Morag, which originated from different cells of the same embryo. (newscientist.com)
  • The latest experiments have also produced three lambs from the cells of a sheep fetus aborted after 26 days, and four from a nine-day-old embryo. (newscientist.com)
  • After growing and dividing for a week or so in a laboratory culture dish, the fused cell forms an early embryo called a blastocyst, which Wilmut's team implants into a surrogate mother. (newscientist.com)
  • In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. (techxplore.com)
  • In fact to get a embryonic stem cell a human embryo has to be disassembled. (ipl.org)
  • People who believe that an embryo should not be destroyed tend to say that embryonic stem cell research should not be conducted. (ipl.org)
  • As an embryo develops, a single fertilized cell progresses through multiple rounds of cell division. (asu.edu)
  • Eventually, the clump of cells goes through a stage called gastrulation, during which the embryo reorganizes itself into the three germ layers: endoderm, ectoderm, and mesoderm. (asu.edu)
  • Between fertilization and the eighth week of gestation, the embryo undergoes multiple cell divisions. (asu.edu)
  • If implantation of the embryo is not contemplated, embryonic human life is static. (jewishvaluesonline.org)
  • In the first 4 - 5 days after fertilization, the early-stage embryo (or blastocyst) is comprised of about 150 cells, within which there is a region called the Inner Cell Mass containing the stem cells. (jewishvaluesonline.org)
  • The controversy arises for some people because, in the course of harvesting these cells, the embryo is destroyed. (jewishvaluesonline.org)
  • The problem is that these cells are made by destroying an unwanted embryo. (ox.ac.uk)
  • Is it right that an embryo dies so that children and adults may live? (ox.ac.uk)
  • Surely then we can use cells from a embryo which will otherwise be flushed down the sink. (ox.ac.uk)
  • The technique used by Reik and his team comes from the 1990s when researchers from the Roslin Institute found a way to turn an adult mammary gland cell taken from a sheep into an embryo. (zmescience.com)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
  • Stem cells are not specialized and the process of their specialization is called differentiation. (benthamscience.com)
  • The learning resource provides an overview of stem cells, explains differentiation, embryonic, adult and induced pluripotent stem cells, theraputic stem cell cloning and stem cells as potential treatment for heart disease and nerve damage. (schoolscience.co.uk)
  • CD24 is involved in regulating B cell apoptosis and in preventing terminal differentiation of B cells into antibody-secreting plasmablasts and plasma cells. (stemcell.com)
  • There is an immense functional heterogeneity among stem cell within a population, considering proliferative capacity and differentiation potential. (uni-heidelberg.de)
  • Derivation and differentiation of haploid human embryonic stem cells. (nature.com)
  • Some of these agents target the embryonic period's "window of susceptibility," three to eight weeks after a pregnant woman's last menstruation, when the highest degree of sensitivity to embryonic cell differentiation and organ formation occurs. (asu.edu)
  • Somatic cells are cells that have gone through the differentiation process and are not germ cells. (asu.edu)
  • Aim: To detect the expression of molecules associated with Notch signaling pathway in stem cells from human exfoliated deciduous teeth (SHED) cultured in specific differentiation medium, namely, keratinocyte growth medium (KGM). (bvsalud.org)
  • Notch-1, Jagged-1, Jagged-2, and stem cell marker Nanog are expressed in SHED cultured in KGM which may be involved in the differentiation into epithelial-like cells in human dental pulp tissues. (bvsalud.org)
  • Since the Notch signaling pathway molecules play an important role in differentiation of epithelial cells, it is important to identify the presence of notch signaling molecules in SHED during the process of cell differentiation. (bvsalud.org)
  • The Notch signaling pathway provides important intercellular signaling mechanisms essential for cell fate specification and it regulates differentiation and proliferation of stem or progenitor cells by para-inducing effects 3-4 . (bvsalud.org)
  • Notch signaling pathway is also involved in the regulation of epithelial cell differentiation in various tissues 5-6 . (bvsalud.org)
  • Stem and progenitor cell populations are often heterogeneous, which may reflect stem cell subsets that express subtly different properties, including different propensities for lineage selection upon differentiation, yet remain able to interconvert. (lu.se)
  • A key challenge is to understand how state, but must also afford flexibility in cell-fate choice to permit the different cell-fate options confronting stem and progenitor cell-type diversification and differentiation in response to cells are selected and coordinated such that adoption of a given intrinsic cues or extrinsic signals. (lu.se)
  • Evidence the fate of stem cells has broad ramifications for biomedical suggests that during development or differentiation, cells make science from elucidating the causes of cancer to the use of very precise transitions between apparently stable ``network stem cells in regenerative medicine. (lu.se)
  • This Study presents the first use in somatic cell nuclear transfer (SCNT) of tooth Pulp cells containing progenitor cells that resemble the nonaging embryonic connective tissue in adults. (yildiz.edu.tr)
  • In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin or intestinal tissues. (techxplore.com)
  • 1983) and the multipotent progenitor cells from fetal disease (Bjorklund and Lindvall, 2000). (lu.se)
  • To varying degrees, these fates also extend to the Such state stability is required in stem and progenitor cells to immediate progeny of stem cells, known as progenitor or support self-renewal and maintenance of the uncommitted transit-amplifying cells. (lu.se)
  • Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
  • The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
  • This was believed to be due to an inability to activate certain embryonic genes. (news-medical.net)
  • But, although the mutation frequency of genes was much lower in ES cells, mutant ES cells accumulated with time in culture. (i-sis.org.uk)
  • But previous approaches required the use of viruses to deliver the four genes needed to activate the cell and accomplish that task. (cbc.ca)
  • Both methods have contributed extensively to our current knowledge on the lineage relation of differentiated cells during embryogenesis, the potential of stem cell populations to generate or re-generate missing cell types, and the cell autonomous or non cell autonomous effects of many genes during development and disease. (uni-heidelberg.de)
  • Mesodermal lineage induction of PLA cells and clones resulted in the expression of multiple lineage-specific genes and proteins. (livingroom.health)
  • hPSC-enriched essential genes mainly encode transcription factors and proteins related to cell-cycle and DNA-repair, revealing that a quarter of the nuclear factors are essential for normal growth. (nature.com)
  • Fig. 2: Analysis of cell-essential genes. (nature.com)
  • explosion further, consider that a fictitious small genome with 2002) More recently and more dramatically, the potential for 260 genes would host the same number of combinations as cell state conversions is exemplified by the reprogramming of the number of atoms in the visible universe! (lu.se)
  • Using tooth Pulp Cells ill SCNT increased the first cleavage rates compared with adult somatic Cells, leading to a higher rate of DNA reprogramming and increased production of an identical embryonic stem cells (ESCs) line. (yildiz.edu.tr)
  • These cells were named Osmangazi Turk Identical ESCs since this was the first use in SCNT of tooth pulp cells to demonstrate a decrease in glucose levels following administration of these cells. (yildiz.edu.tr)
  • One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
  • SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
  • This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
  • But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
  • Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
  • Successful somatic-cell nuclear transfer (SCNT) depends on the quality, availability and maturation of the animal's unfertilized oocytes. (nature.com)
  • For SCNT, the chromosomes of the unfertilized canine oocytes were removed by micromanipulation, and a single donor cell was transferred into each enucleated oocyte. (nature.com)
  • Once the SCNT is done, the cloning is over. (nationalrighttolifenews.org)
  • The cloning is completed when the SCNT is accomplished. (nationalrighttolifenews.org)
  • In January 2007, researchers at Wake Forest University reported that "stem cells drawn from amniotic fluid donated by pregnant women hold much of the same promise as embryonic stem cells. (wikipedia.org)
  • According to modern stem cell researchers, Spain is one of the leaders in stem cell research and currently has one of the most progressive legislations worldwide with respect to human embryonic stem cell (hESC) research. (wikipedia.org)
  • But their chief objection - that obtaining stem cells requires killing a human being - is about to become moot, as researchers have discovered that human adult stem cells can be differentiated into neural tissue in chicken eggs . (blogspot.com)
  • And the researchers have already accomplished the first step, creating embryonic stem-like cells from the tissue of an endangered adult snow leopard ( Panthera uncia ). (scientificamerican.com)
  • The researchers stopped well short of creating a human clone. (nationalrighttolifenews.org)
  • US researchers have reported a breakthrough in stem cell research, describing how they have turned human skin cells into embryonic stem cells for the first time. (nationalrighttolifenews.org)
  • In the first report [2], researchers from Edinburgh and Oxford took cells from the mouse brain marked with transgene 1, and cultured them together with ES cells marked with a second transgene, 2. (i-sis.org.uk)
  • These researchers pointed out that the spontaneous fusion rate (without interleukin-3) was extremely low, between 2-11 per million bone marrow cells, and is unlikely to account for all the findings with adult stem cells. (i-sis.org.uk)
  • In the current issue of the same journal [6], researchers compared the frequency and type of mutation induced in embryonic stem cells and embryonic somatic cells. (i-sis.org.uk)
  • After more than 25 years of experiments with embryonic stem cells in animal models, researchers have yet to develop one successful treatment in mice for any disease that could be used as a model to undertake the first steps for a clinical trial with human patients. (freerepublic.com)
  • Researchers create embryonic stem cells mature cells turn off some of the epigenetic controls that Stem Cell Science Frequently Asked Questions. (curtisrobertmacdonald.com)
  • However, researchers at the Harvard Stem Cell Institute say reprogrammed cells won't eliminate the need or value of studying embryonic stem cells. (cbc.ca)
  • Researchers value the cells for their ability to replicate quickly and turn into any kind of human tissue. (christianitytoday.com)
  • The prolife lobby also received help from Do No Harm, a coalition of researchers, bioethicists, and doctors who spearheaded a nationwide petition urging Bush to oppose destructive human embryonic stem-cell research. (christianitytoday.com)
  • The researchers wanted to see whether "mature" cells that have differentiated to fulfil a specialised role (such as that of an udder cell or a fetal cell) could be returned to a primitive state from which they could grow into entire organisms. (newscientist.com)
  • For each clone, the Roslin researchers combine material from two sources. (newscientist.com)
  • Next, the researchers take cells containing donor genetic material. (newscientist.com)
  • 18 Sep, 2007 12:13 pm Rice University researchers have engineered musculoskeletal cartilages with human embryonic stem cells, with the hope of eventually using the neotissue. (scitizen.com)
  • 6 Jun, 2007 07:00 pm Researchers have reprogrammed skin cells into embryonic stem cells. (scitizen.com)
  • UK researchers have rejuvenated the skin cells of a 53-year-old woman so they are the equivalent of a 23-year-olds. (zmescience.com)
  • These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)
  • Biotech products include protein drugs made by genetically-engineered cell cultures, monoclonal antibodies (laboratory-made copies of a single human antibody, often for use in cancer treatment ) and, most recently, human cell-based therapies. (eurostemcell.org)
  • Cell therapies are treatments that use human cells, including stem cells, with the aim of restoring, maintaining, or improving the functioning of human tissues or organs. (eurostemcell.org)
  • There are currently around 50 firms developing cell therapies within Europe. (eurostemcell.org)
  • Companies face a choice between a range of human cell types to work with when developing new therapies. (eurostemcell.org)
  • The REMEDiE project identified some 65 cell therapies under development in the European commercial sector. (eurostemcell.org)
  • There are more cell therapies than firms because several firms have more than one product in development. (eurostemcell.org)
  • European cell therapy firms are split almost equally between therapies based on stem cells and therapies based on somatic cells. (eurostemcell.org)
  • In May 2007, Ontario and California announced a $30-million stem cell research deal aimed at finding new therapies for those diseases. (cbc.ca)
  • Biotechnology companies specializing in stem-cell research stand to reap huge financial windfalls from successful therapies developed via this science," said the CPI report. (christianitytoday.com)
  • Should expensive therapies derived from stem cell research be covered universally by health insurance? (prospect.org)
  • Highly plastic adult stem cells from a variety of sources, including umbilical cord blood and bone marrow, are routinely used in medical therapies. (techxplore.com)
  • Because the early stem cells have the ability to become any one of the hundreds of different kinds of human cells, scientists are working on research using these cells with the aim of creating therapies to treat a variety of diseases. (jewishvaluesonline.org)
  • For instance, it may be possible one day to produce cardiac tissue to repair a heart damaged in a heart attack, nerve tissue to repair spinal cord injuries and cell therapies to treat people suffering from Alzheimer's or ALS. (jewishvaluesonline.org)
  • Example: In Japan, scientists have discovered the chemical that induces bone marrow to produce healing cells. (nationalrighttolifenews.org)
  • The chemical which summons stem cells from bone marrow to the site of a wound has been discovered by scientists in the UK and Japan. (nationalrighttolifenews.org)
  • Scientists at Osaka University and King's College London gave mice bone marrow cells that glow green - which can be tracked while moving round the body. (nationalrighttolifenews.org)
  • Scientists have used cloning technology to transform human skin cells into embryonic stem cells, an experiment that may revive the controversy over human cloning. (nationalrighttolifenews.org)
  • The method described on Wednesday by Oregon State University scientists in the journal Cell, would not likely be able to create human clones, said Shoukhrat Mitalipov, senior scientist at the Oregon National Primate Research Center. (nationalrighttolifenews.org)
  • Professor Alan Mackay Sim's Queensland team of scientists working on nasal stem cell research for spinal cord injuries and Professor Pritinder Kaur's team at Peter MacCallum Cancer Centre working on using adult stem cells for burns victims are both supported by grants from the Sydney archdiocese. (freerepublic.com)
  • Some of the most serious A significant hurdle to this use and most uses of stem cells is that scientists do not yet it may become possible to generate healthy What specific types of conditions can stem cell therapy help treat? (curtisrobertmacdonald.com)
  • Long before the controversy emerged over human embryonic stem cells, scientists and doctors began using first-generation stem cells from adult bone marrow. (eppc.org)
  • But they are also less equipped to produce every cell type of the body and less able to reproduce themselves indefinitely, which makes them less appealing to scientists interested in basic research. (eppc.org)
  • In July 2005, for example, scientists announced that they had engineered adult mouse stem cells into usable mouse eggs, a technique that might one day allow for the creation of human eggs from ordinary human cells. (eppc.org)
  • Umbilical Cord Blood Storage Company Sees Growth Umbilical Cord Stem Cell Storage Resources Arkansas House Votes to Create Umbilical Cord Stem Cell Bank Scientists Claim They Discovered Molecule That Might Help Embryonic Stem Cells Grow US Senate Vote for. (physiciansforlife.org)
  • Scientists have been all abuzz in the last few years over stem cells - cellular magicians that promise to dazzle and amaze. (cbc.ca)
  • Scientists say embryonic stem cells are the most useful type because they have the potential to become any type of cell within the body. (cbc.ca)
  • Scientists are fascinated by the ability of stem cells to become any type of cell. (cbc.ca)
  • "PrimeGen , based in Irvine, California, says that its scientists have converted specialised adult human cells back to a seemingly embryonic state - using methods that are much less likely to trigger cancer than those deployed previously. (cbc-network.org)
  • The company also claims to be able to produce reprogrammed cells faster and much more efficiently than other scientists. (cbc-network.org)
  • Research in the stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s. (techxplore.com)
  • Scientists have found a way to possibly avoid using embryonic stem. (scitizen.com)
  • In the second half of the twentieth century, scientists learned how to clone organisms in some species of mammals. (asu.edu)
  • 1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)
  • The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)
  • In biology , cloning is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria , insects or plants reproduce asexually . (wikiquote.org)
  • The junk biology is flying in the media's descriptions of the now accomplished human cloning. (nationalrighttolifenews.org)
  • One of the greatest controversies triggered tissue, a stem cell encoding for heart tissue by the rapid pace of evolution in biology, will eventually develop into heart tissue particularly in genomics and biotechnology, and so on. (who.int)
  • Understanding cell-fate decisions in stem cell populations is a major goal of modern biology. (lu.se)
  • Human cloning is intrinsically illicit in that, by taking the ethical negativity of techniques of artificial fertilization to their extreme, it seeks to give rise to a new human being without a connection to the act of reciprocal self-giving between the spouses and, more radically, without any link to sexuality. (archdiocese-no.org)
  • We now have the right mechanism for sourcing cells without ethical quibbles,' said Peter Mountford, head of the Melbourne- and London-based Stem Cell Sciences. (freerepublic.com)
  • Stem cell research and ethical dilemmas How far have we. (curtisrobertmacdonald.com)
  • Stem cell research and ethical dilemmas: How far have The two possible suggestions to counteract this slope is to either Stem cell uses have advanced, Some unipotent stem cells, such as mesenchymal stem cells. (curtisrobertmacdonald.com)
  • Keep in mind, this is ethical adult stem cell research, which is in human clinical trials, helping patients NOW. (cbc-network.org)
  • The life-enhancing promise of stem cell research is just too potent and the ethical questions too tricky to leave the issue in the hands either of private entrepreneurs or religious fundamentalists, much less both. (prospect.org)
  • Ethical Stem Cell Breakthrough! (scitizen.com)
  • Embryonic stem cell transplants have been an ethical, social, and legal controversy since the first successful transplant of human stem cells in 1998. (ipl.org)
  • Cloning technology, however, is perceived as having the potential for reproductive cloning, which raises serious ethical and moral concerns. (who.int)
  • Stem cells come in three forms: embryonic stem cells, embryonic germ cells and adult stem cells. (cbc.ca)
  • However, GCTs, including seminomas, can occur in extragonadal sites along the midline of the body, following the embryologic migration route of its precursor cells -- the primordial germ cells. (medscape.com)
  • This paper outlines the debates prompted through a reproduction mechanism involv- by progress in cloning research, with special ing male and female germ cells. (who.int)
  • Mouse nuclear transfer embryonic stem cells (NT-ESCs) were first established in 2000, and then proved to be able to differentiate either in vivo or in vitro, and give rise to individual tissues through germ line transmission or tetraploid complementation. (benthamscience.com)
  • The power of stem cells is that they can differentiate into all the cell types in the body," Verma said in a prepared release . (scientificamerican.com)
  • Neither report cited a paper published last year in the journal Blood [4], where a group from the Stem Cell Institute, Department of Medicine, and Cancer Center, University of Minnesota Medical School, Minneapolis, reported the most comprehensive experiments proving that a single adult stem cell can differentiate into all cell types in culture. (i-sis.org.uk)
  • The cells could be made to differentiate into bone forming cells, cartilage forming cells, fat cells, skeletal muscle cells and endothelial cells. (i-sis.org.uk)
  • cells that behave very like embryonic stem cells and can differentiate into all the different types of cells in the body. (eurostemcell.org)
  • Undifferentiated cells, found in a differentiated tissue, that can renew themselves and - with certain limitations - differentiate to yield all the specialized cell types of the tissue from which they originated. (michaeljfox.org)
  • The have been applied to both the plant and ani- stem cells possess pluripotential charac- mal kingdoms without even stirring a ripple teristics, and can differentiate into various of concern in international conscience [ 2 ]. (who.int)
  • SHED was able to differentiate into epithelial like cells when cultured in keratinocyte growth medium (KGM) 2 . (bvsalud.org)
  • Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)
  • Stem cells are cells found in most, if not all, multi-cellular organisms. (wikipedia.org)
  • The term applies not only to entire organisms but also to copies of molecules (such as DNA) and cells. (who.int)
  • Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
  • However, regardless of how strongly you support life, you may unknowingly be cooperating in aborted fetal cell research by purchasing products that use aborted fetuses either in the product itself or in its development. (hli.org)
  • However, tissue rejection following ESCs derivatives transplantation greatly hinders its application. (benthamscience.com)
  • Some in vivo transplantation studies have reported robust (35-50%) levels of transdifferentiation, which makes it unlikely that the results are due to cell fusion events. (i-sis.org.uk)
  • 1999). Majority of the organs for transplantation are donated from patients in whom brain-stem death has been diagnosed and who are then ventilated to maintain adequate oxygenation and circulation-the so called non-heart-beating donors (NHBDs) (D Allessandro et al . (scialert.net)
  • Historically, lineage analysis in vertebrates was performed on entire populations of cells using either transplantation approaches or genetic tools like Cre/LoxP mediated recombination. (uni-heidelberg.de)
  • Most importantly, embryonic stem cells may allow transplantation to be used to treat common diseases like heart attack, Alzheimer's Disease, diabetes, Parkinson's Disease and stroke. (ox.ac.uk)
  • as well as diagnostic techniques, drug development and tissue transplantation. (who.int)
  • Elaboration of an international convention against reproductive cloning of human beings has been under consideration in the United Nations since December 2001 when the subject was included in the agenda of the fifty- sixth session as a supplementary agenda item at the request of France and Germany. (who.int)
  • 2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
  • 3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
  • 7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
  • 3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
  • Dermal fibroblasts were taken from a 35-year old male and a 75-year-old male and used to create embryonic stem cells. (news-medical.net)
  • Donor fibroblasts were obtained from an ear-skin biopsy of a male Afghan hound and cultured for two to five passages (in which fully grown cells are transferred to a new culture dish). (nature.com)
  • They found that the spontaneous mutation frequency in ES cells is 100-fold lower than that in mouse embryonic fibroblasts (a somatic cell line), which is similar to adult cells in vivo . (i-sis.org.uk)
  • Human CMV grows only in human cells and replicates best in human fibroblasts. (medscape.com)
  • 2008). Historically, this concept is highlighted by the experi- factors are key intrinsic regulators of these fate decisions and mental phenomenon of lineage reprogramming, for example, that fate choice involves modulating networks of transcription by the conversion of fibroblasts to muscles cells following trans- factors. (lu.se)
  • 7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)
  • Wilmut and his colleagues fuse the empty oocyte with the donor cell by bringing them together and subjecting them to an electric current. (newscientist.com)
  • Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells. (nature.com)
  • Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
  • This latest anti-publicity on adult stem cells comes on the heels of a paper announcing success in embryonic stem (ES) cell transplant in a Parkinson rat model published in the house journal of the United States National Academy of Sciences [5]. (i-sis.org.uk)
  • Neither the title of the paper, nor the abstract mentioned that in the experiment, five out of 25 rats receiving the transplant died with "teratoma-like tumors" in their brains, a well-known hazard of ES cells. (i-sis.org.uk)
  • Mammary glands are rich in these cells, which are more adaptable than other tissue. (newscientist.com)
  • Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)
  • Stem cell laws are the law rules, and policy governance concerning the sources, research, and uses in treatment of stem cells in humans. (wikipedia.org)
  • Embryonic stem cells were isolated in mice in 1981, and in humans in 1998. (wikipedia.org)
  • Help us to be faithful to this sacred trust so that we may protect and promote the dignity of every human life from the very moment of conception, particularly the tiniest humans in the embryonic stage of human development who are so often forgotten by society & used by modern science. (archdiocese-no.org)
  • If the same could be achieved in humans, it would mean that each of us could have clones of ourselves made from our own tissue. (newscientist.com)
  • But if, as seems likely, the Roslin team has succeeded in making an entire animal from adult tissue, it might be possible to do the same for humans. (newscientist.com)
  • My lab is interested in understanding stem cells, a fascinating type of cell that can self-renew and is responsible to generate once and again the cells that we humans (and most other animals) lose on daily basis - skin cells, blood cells, intestine cells. (uni-heidelberg.de)
  • It weighs more than one kilogram in adult humans, and it covers a surface area of 4000 to 7000 square meters. (asu.edu)
  • 2002). In humans, SSEA4 is expressed by building the nervous system but also for their prospec- nonneural cells such as the erythrocytes (Kannagi et al. (lu.se)
  • Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
  • Verma said these cells can be used either for cloning or to grow eggs or sperm in a lab. (scientificamerican.com)
  • The cells could also be stored in cryopreservation for future use when eggs and sperm are too difficult to collect or freeze. (scientificamerican.com)
  • 6 Sep, 2007 12:57 pm British authorities decided yesterday to permit research that uses animal eggs to create human stem cells because of the limited supply of human eggs. (scitizen.com)
  • We discuss these properties with examples both from the hematopoietic and embryonic stem cell (ESC) systems. (lu.se)
  • But recent evidence suggests it may be possible to reprogram adult stems to repair tissues. (cbc.ca)
  • Additionally, the so touted "potential benefits" are in this case more than questionable, given the great unresolved medical problems - including their propensity to create tumors - that embryonic stem cells pose. (catholicphilly.com)
  • Adult stem cells are easier to control than embryonic stem cells and thus less likely to form tumors. (eppc.org)
  • The risk is increased 1000-fold for squamous cell carcinoma, basal cell carcinoma, malignant melanoma, and fibrosarcoma and is increased 10-fold to 20-fold for other tumors. (medscape.com)
  • information on stem cells, cloning and What diseases and conditions can be treated with stem cells? (curtisrobertmacdonald.com)
  • Potential benefits of stem of stem cells and the realization of these uses, Some of the potential uses of stem cells are to study the way cells function and hopefully that will lead to cures for various diseases like cancer. (curtisrobertmacdonald.com)
  • Already, non-embryonic stem cells are being used to treat a variety of diseases-most notably certain cancers of the blood. (eppc.org)
  • Since then, there has been a flurry of announcements about developments in stem cell research and hints of promising treatments for diseases such as Alzheimer's, Parkinson's and cancer. (cbc.ca)
  • This makes them perfect for a wide range of medical uses, from repairing tissue to treating diseases such as Parkinson's and Alzheimer's. (cbc.ca)
  • The cells carry the potential to cure neurological diseases, diabetes, and many other illnesses. (christianitytoday.com)
  • While at the hospital she was unaware that the doctors there were experimenting on her taking cell samples from her body, to help find a resolution to multiple diseases. (ipl.org)
  • All of this debate raises an important question, Should embryonic stem cell research be conducted for treatment of present and future diseases? (ipl.org)
  • On the other hand, people who believe that embryonic stem cell research creates means of curing diseases reply that the research should be conducted. (ipl.org)
  • This could also be done with other tissues in the body to develop treatments for age-related diseases such as diabetes, they argue. (zmescience.com)
  • However, the use of stem cells to treat diseases is still extremely limited in the present day. (zmescience.com)
  • In English, this means no need for abortions or embryonic cloning, as the cells can be sourced from the patient's own bone marrow (eliminating rejection problems into the bargain). (blogspot.com)
  • In the second report [3], mouse bone marrow cells marked with green fluorescent protein were found to fuse with ES cells in culture in the presence of the cytokine, interleukin-3, which is known to encourage cell fusion. (i-sis.org.uk)
  • Much of the work conducted on adult stem cells has focused on mesenchymal stem cells (MSCs) found within the bone marrow stroma. (livingroom.health)
  • Adipose tissue, like bone marrow, is derived from the embryonic mesenchyme and contains a stroma that is easily isolated. (livingroom.health)
  • The report notes that the AAR, which bills itself as the leading citizen advocacy organization for improving the health of older Americans, "also happens to receive funding from private-sector biotechnology companies that have a financial stake in the outcome of the stem-cell debate, including Geron," the for-profit corporation that isolated embryonic stem cells in 1998. (christianitytoday.com)
  • In this article R. Alta Charo states that we have a right to use fetal tissue for research and therapy (Fetal Tissue, 1) The article goes into how a lot of people find this to be a moral issue and a matter of the conscience and explains how the antiabortion activist that don't agree with the research are actually benefitting from the fetal tissue. (ipl.org)
  • ESCs derived from tooth Pulp cells using this method were observed to transfer into pancreatic beta Cells using transmission electron microscopy. (yildiz.edu.tr)
  • What is more, by deriving NT-ESCs from patient cells, the problem of immune rejection may be avoided. (benthamscience.com)
  • These cells have been described as embryonic stem cells (ESCs) and. (scitizen.com)
  • We are tackling functional heterogeneities on somatic stem cells by combining metabolic reporters in vivo with lineage progression. (uni-heidelberg.de)
  • Egg harvesting and Embryonic Stem-cell Research Pose Serious Threat to Women's Health A congressional hearing last Thursday raised awareness on the risks to women's health and fertility by in vitro fertilization (IVF), human cloning, embryonic stem-cell. (physiciansforlife.org)
  • As a consequence, clones created from a cell taken from an adult might have chromosomes that are already shorter than normal, which may condemn the clones' cells to a shorter life span. (wisdomanswer.com)
  • This was confirmed by examining the cells chromosomes and identifying the distinctive chromosomes from both mouse lines. (i-sis.org.uk)
  • The fused cells were found to have 4 to six sets of chromosomes by DNA analysis, and they behaved as ES cells when tested. (i-sis.org.uk)
  • They then remove the original chromosomes from these to leave DNA-free cells. (newscientist.com)
  • Ectoderm is one of three germ layers--groups of cells that coalesce early during the embryonic life of all animals except maybe sponges, and from which organs and tissues form. (asu.edu)
  • In the normal course of gestation, these cells will divide and split off from one another to become every cell in the human body, forming the various organs and tissues. (jewishvaluesonline.org)
  • The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)
  • However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
  • Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
  • The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)
  • The team at OHSU [Oregon Health and Science University], which disclosed its work in a paper published online by Cell, created embryonic stem cells by replacing the nucleus in an unfertilized human egg with the nucleus from a skin cell, then harvesting the resulting stem cells. (nationalrighttolifenews.org)
  • When the nucleus of a stem cell has been the technique of cloning. (who.int)
  • The basic techniques of of the implanted nucleus, when it fully cloning have been known for some time, and develops. (who.int)
  • Finally, PLA cells exhibited unique characteristics distinct from those seen in MSCs, including differences in CD marker profile and gene expression. (livingroom.health)
  • Similarly, GATA-1 has been shown to induce lineage switching expression values even if, for simplicity, we assume only ``on'' of committed cells in hematopoiesis, first in cell lines (Kulessa and ``off'' states for each gene. (lu.se)
  • This long-sought technique may eventually let doctors create replacement cells for a wide variety of tissues from bits of a patient's own skin. (nationalrighttolifenews.org)
  • Since its discovery, NGF has been found to act in a variety of tissues throughout development and adulthood. (asu.edu)
  • With an eye on the potential economic benefits of being a biotechnology-friendly state, the same bill authorized the creation of an adult stem cell center. (sagepub.com)
  • Also stem cells from umbilicus cord blood. (blogspot.com)
  • These include 'adult' differentiated cells of the body (known as somatic cells, e.g. skin cells) and stem cells from a range of sources - embryonic, foetal, cord blood, and mature tissues. (eurostemcell.org)
  • Blood Stem Cells Clinical Trials Cord Blood Eye Disease. (curtisrobertmacdonald.com)
  • Today, we can derive stem cells from a range of adult and newborn tissues: liver cells, kidney cells, brain cells, fat cells, and umbilical cord blood. (eppc.org)
  • Last May, the House of Representatives passed a bill to create a cord blood stem cell bank, legislation that is likely to become law with virtually unanimous support. (eppc.org)
  • General Assembly the following year,3 and the World Medical Association's Resolution on Cloning, endorsed in 1997, have confronted the issue but lack binding legal force. (who.int)
  • According to the National Conference of State Legislatures, one of the top ten issues that will come before state legislatures this year (2006) relates to rights of conscience in the biomedical field - stem cell experimentation and research. (consciencelaws.org)
  • A few years ago, in an article in the The Times of London newspaper, the author, Michael Gove, made the following statement: "Embryonic stem-cell experimentation involves not just the destruction of human life but the creation of life with the specific intent to destroy it. (jewishvaluesonline.org)
  • Second, Michael Gove holds that embryonic experimentation represents the destruction of human life. (jewishvaluesonline.org)
  • Stem cell treatments are a type of cell therapy that introduce new cells into adult bodies for possible treatment of cancer, somatic cell nuclear transfer, diabetes, and other medical conditions. (wikipedia.org)
  • Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
  • More than 100 nuclear transfer procedures could be required to produce one viable clone. (wikiquote.org)
  • Here we describe the cloning of two Afghan hounds by nuclear transfer from adult skin cells into oocytes that had matured in vivo . (nature.com)
  • Figure 1: Dog cloned by somatic-cell nuclear transfer. (nature.com)
  • Stem cells can now be grown and transformed into specialized cells with characteristics consistent with cells of various tissues such as muscles or nerves through cell culture. (techxplore.com)
  • Cloning or clone reproduction is an in vitro process of obtaining multiple copies of the same organism using molecular biological and genetic engineering techniques. (wisdomanswer.com)
  • Why is tissue culture asexual reproduction? (wisdomanswer.com)
  • Plant cloning, such as the use of plant tissue culture techniques, is an asexual reproduction of plants to produce duplicates from one plant specimen. (wisdomanswer.com)
  • Is cloning asexual reproduction? (wisdomanswer.com)
  • Clones are cells that have come from asexual reproduction or a parent cell. (wisdomanswer.com)
  • What's the difference between Clone reproduction and asexual reproduction? (wisdomanswer.com)
  • The key difference between asexual reproduction and clone reproduction is the setting of the process. (wisdomanswer.com)
  • While other countries are publishing important studies showing tremendous progress in clinical trials for organ and tissue repair using adult stem cells, our country continues to be obsessed with embryonic stem cell research to our own detriment. (catholicphilly.com)
  • They are still developing and they have the potential to become any of the major specialized cell types within that organ. (cbc.ca)
  • 8 Jun, 2007 04:13 pm Stem cells provide the starting material for the development and repair of every organ and tissue in the body and they are present in all stages of life. (scitizen.com)
  • In collaboration with mathematicians, we focus on how many stem cells and stem cell types are required to setting up a functional organ during embryogenesis and in an already developed organism. (uni-heidelberg.de)
  • We have generated several transgenic lines to explore how neuromasts are created after embryonic development (Development 144, 687-697), which are their cells of origin and which and how they integrate the signals from the environment to trigger organ formation. (uni-heidelberg.de)
  • The embryonic period or critical period is when most organ systems form, whereas the fetal period, week eight to birth, involves the growth and modeling of the organ systems. (asu.edu)
  • Is it permissible to directly kill human beings to make them the object of scientific research or to save other adult human beings? (catholicphilly.com)
  • WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)