When compared to conventional clear cell renal cell carcinoma (RCC), the prognosis of non-metastatic PRCC is more favorable, whereas a relatively worse outcome was reported in patients with metastatic disease. (wikipedia.org)
The efficacy of anti-angiogenic treatment by targeting VEGF/VEGF receptors in metastatic clear cell renal cell carcinoma (ccRCC) varies from patient to patient. (bvsalud.org)
Cell carcinomas4
Biopsies, however, are also unreliable because oncocytoma-like areas can be found in chromophobe renal cell carcinomas. (pediagenosis.com)
The presence of fat, however, is not pathognomonic for AML, since certain primary renal sarcomas (such as liposarcoma) and rare renal cell carcinomas may also contain fat. (pediagenosis.com)
The classification of epithelial tumors of the kidney has in particular undergone substantial progress in the last two decades with major contributions from genetic typing of renal cell carcinomas (RCCs). (abdominalkey.com)
Determination of subtypes of cystic renal cell carcinomas by imaging is still challenging due to overlap of common imaging features. (radiologykey.com)
Tubular4
Papillary renal cell carcinoma (PRCC) is a malignant, heterogeneous tumor originating from renal tubular epithelial cells of the kidney, which comprises approximately 10-15% of all kidney neoplasms. (wikipedia.org)
Mucinous tubular and spindle cell carcinoma of the kidney is a rare and a distinctive renal tumor with a relatively indolent behavior. (journalmc.org)
Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare variant of renal cell carcinoma, which has recently been described in case reports or small series [ 1 ]. (journalmc.org)
Renal cell carcinoma (RCC), the most common kidney neoplasm, originates in renal tubular epithelial cells and accounts for 85-90% of adult renal malignancies [ 1 ]. (biomedcentral.com)
Tumors10
There are several different kinds of benign renal tumors, which may originate from a wide range of cell types. (pediagenosis.com)
Solid renal tumors, however, are generally malignant, with the probability of malignancy strongly correlating with tumor size. (pediagenosis.com)
Some of the more common and well-documented benign renal tumors are presented here. (pediagenosis.com)
Oncocytomas account for approxmately 5% of renal tumors in adults. (pediagenosis.com)
Like other renal tumors, AMLs are often discovered as incidental findings on axial imaging. (pediagenosis.com)
Fat-poor tumors that cannot be confidently distinguished from renal cell carcinoma should also be removed. (pediagenosis.com)
The role of genotyping and ancillary tools, in particular immunohistochemistry, in correctly classifying these tumors is highlighted in the section on Renal Cell Carcinoma. (abdominalkey.com)
More than 80% of renal tumors of childhood are Wilms tumor (nephroblastoma) ( 1 , 2 ). (abdominalkey.com)
Grossly, tumors presented as well-circumscribed solid masses, contained in the renal capsule in all cases. (journalmc.org)
Cystic renal tumors, overall, have excellent prognosis and less aggressive metastatic behavior compared with solid renal tumors. (radiologykey.com)
Malignant3
Bosniak classification is based on findings on contrast-enhanced CT scans, dividing renal cysts into 4 broad categories (I-IV) proposed to distinguish malignant from benign cystic lesions. (radiologykey.com)
The prognosis of renal cell carcinoma (RCC) malignant neoplasms deeply relies on an accurate determination of the histological subtype, which currently involves the light microscopy visual analysis of histological slides, considering notably tumor architecture and cytology. (bvsalud.org)
Chromophobe1
In this study, we investigate the automatic RCC subtyping classification of 91 patients, diagnosed with clear cell RCC, papillary RCC, chromophobe RCC, or renal oncocytoma, through deep learning based methodologies. (bvsalud.org)
Papillary3
Type 1 PRCC, also known as a renal tumor caused by a genetic predisposition of hereditary papillary renal cancer syndrome, compromises approximately 25% of all PRCCs. (wikipedia.org)
Its large spherical nuclei on papillary cores are arranged in a pseudo-stratified manner. (wikipedia.org)
Regarding hereditary conditions, patients with hereditary papillary renal cancer syndrome showed a greater risk of type 1 PRCC, whereas those with hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome have an increased risk of type 2 PRCC. (wikipedia.org)
Kidney1
standard diet [Term] id: XCO:0000017 name: nephrectomy def: "Surgical removal of kidney. (mcw.edu)
Tumor3
In 2014, PRCC was first acknowledged as a renal tumor subtype by the World Health Organization (WHO) considering its distinct genetic, molecular and histologic characteristics. (wikipedia.org)
Commonly encountered cysts on ultrasound (US) and cross-sectional imaging (CT and MR imaging) mostly are benign simple cortical renal cysts. (radiologykey.com)
Complex cysts, on imaging, may be seen as part of benign cysts, renal infection, and cystic neoplasms, including cystic renal cell carcinoma (RCC), which can be distinctly identified due to characteristic imaging features. (radiologykey.com)
Imaging plays a critical role in management, differentiating benign cysts, which do not require treatment, from cystic neoplasms, which may benefit from partial or radical nephrectomy, or percutaneous ablation under imaging guidance. (radiologykey.com)
AIMS: Onychomatricoma (OM), an uncommon benign fibroepithelial neoplasm of the nail unit, is sometimes diagnostically challenging for clinicians and pathologists. (bvsalud.org)
Cystic1
Contrast-enhanced ultrasound evaluation is a safe alternative imaging modality for the assessment of complex cystic renal masses in patients with renal impairment. (radiologykey.com)
Mesenchymal1
This is followed by coverage of neoplasms in the more traditional categories of epithelial, mesenchymal, and other categories. (abdominalkey.com)
Diagnosis4
Thus even a suspected oncocytoma is generally treated like a renal cell carcinoma, with the definitive diagnosis established only after surgical resection of the entire mass. (pediagenosis.com)
Histological slides were reviewed and diagnosis of renal MTSCC was based on the criteria established by the WHO classification system [ 2 , 3 ]. (journalmc.org)
RCC subtyping is therefore a time-consuming and tedious process, sometimes requiring expert review, with great impact on diagnosis, prognosis and treatment of RCC neoplasms. (bvsalud.org)
Through a multi modal approach, Radiologists will familiarize with these conditions and guarantee a correct diagnosis not only in paediatric patients but also in the adult population. (esur2023.com)
Cysts2
Renal cysts are common incidental findings on imaging studies performed for nonurologic indications. (radiologykey.com)
Since its introduction in 1986, Bosniak classification for renal cysts has been used by radiologists and urologists as a method to stratify patients to plan treatment. (radiologykey.com)
Histological1
The post operative histological evaluation revealed unsuspected squamous cell carcinoma of renal pelvis with concomitant xanthogranulomatous pyelonephritis. (shengsci.com)
Partial3
Nephrectomy or partial nephrectomy is usually recommended for PRCC treatment, often accompanied with several targeted molecular therapies to inhibit metastatic spread. (wikipedia.org)
All patients were treated by nephrectomy (radical in 2 cases and partial in 2 cases). (journalmc.org)
It is more frequently reported in urinary bladder and male urethra than renal pelvis. (shengsci.com)
Squamous cell carcinoma of renal pelvis is usually associated with nephrolithiasis. (shengsci.com)
The ureteric bud divides and branches forming the collecting system (renal pelvis, infundibulae, calyces, and tubules) for urine drainage. (esur2023.com)
Undergone1
We report two such cases detected incidentally in patients who have undergone nephrectomy for hydronephrosis. (shengsci.com)
Vein1
There was no invasion in the surrounding perinephric fat or in the renal vein in the hilum. (journalmc.org)
Ultrasonography1
Imaging exploration (ultrasonography and computed tomography scan) showed a well-circumscribed renal mass ( Fig. 1 ) in all the cases (3 left-sided and 1 right-sided mass). (journalmc.org)
Masses1
AMLs can often be distinguished from other renal masses using computed tomography (CT) because their fat content causes them to appear as hypoattenuating lesions (less than 20 Hounsfield units). (pediagenosis.com)
Surgical2
A high index of suspicion should be maintained with an aim of surgical treatment for selected patients with large and symptomatic adrenal lipomatous lesions. (bmj.com)
surgical removal created_by: mshimoyama creation_date: 2011-11-02T02:06:00Z [Term] id: XCO:0000018 name: bilateral nephrectomy def: "Surgical removal of both kidneys. (mcw.edu)
Commonly1
Accounting for 25% of PRCCs, type 2 PRCC is the pathological subtype that is most commonly associated with hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome. (wikipedia.org)
Patients4
70% to 80% of patients with tuberous sclerosis develop renal AMLs, typically in their fourth decade. (pediagenosis.com)
All patients were female without history of genitourinary or renal malignancy. (journalmc.org)
These patients require several follow-up examinations for longitudinal evaluation, allowing the natural course of growth to reveal a neoplasm warranting intervention. (radiologykey.com)
However, local recurrence or distant metastasis still occur in some patients even after radical nephrectomy. (biomedcentral.com)
Genetic1
Possible risk factors have been identified that contribute to PRCC development, which include genetic mutations, hereditary syndrome, renal injuries, and lifestyle factors. (wikipedia.org)
Cases1
As with other types of renal cell cancer, most cases of PRCC are discovered incidentally without showing specific signs or symptoms of cancer. (wikipedia.org)
Smooth1
Sagittal and transverse B-mode US images show left renal cyst with thin smooth internal septations ( A ), which does not show internal vascularity on color doppler image ( B ). Coronal T2W images ( C ) show left renal cyst with smooth thin wall and septations. (radiologykey.com)
Broad1
Herein, we present a case of unusually large broad ligament ependymoma in a 32-year-old female with pain and lump in the lower abdomen. (shengsci.com)