Adult cells cloning and stem cell. Medical search. Frequent questions

This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)
In the current issue of the same journal [6], researchers compared the frequency and type of mutation induced in embryonic stem cells and embryonic somatic cells. (i-sis.org.uk)
So far the reprogramming of somatic cells shows very low rates of efficiency (~0.0006-1%) that have not improved in the last two decades of continuous research. (sibi.org)
In reality, gene somatic cells to a pluripotent cell state by a handful of transcrip- expression is graded, making the potential gene expression tion factors (Takahashi and Yamanaka, 2006). (lu.se)

Bovine fetal mesenchymal stem cells exert antiproliferative efect against mastitis causing pathogen Staphylococcus aureus. (sciendo.com)
Which Cosmetics Use Fetal Cells? (hli.org)
However, regardless of how strongly you support life, you may unknowingly be cooperating in aborted fetal cell research by purchasing products that use aborted fetuses either in the product itself or in its development. (hli.org)
Your children might enjoy using coffee creamers and eat soup with artificial flavor enhancers (Senomyx and Firmenich) tested on artificial taste buds engineered from aborted fetal cells. (hli.org)
To do this, they had to produce an army of never-tiring taste testers - that is, flavor receptors engineered from human embryonic kidney cells (HEK-293, a fetal kidney cell line popular in pharmaceutical research). (hli.org)
The merge does not seem to have stopped the use of aborted fetal cells in development. (hli.org)
The fetal skin cell line that PSPs are based on was taken from an electively aborted baby whose body was donated to the University. (hli.org)
The Vaccine Chart of the Sound Choice Pharmaceutical Institute (SCPI) lists dozens of vaccines and medical products that contain aborted fetal cell lines. (hli.org)
The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)
1983) and the multipotent progenitor cells from fetal disease (Bjorklund and Lindvall, 2000). (lu.se)
Upon differentiation, other ELLU clones shift from fetal to adult hemoglobin expression, giving rise to more mature cells. (lu.se)

National Institutes of Health (NIH) Frequently Asked Questions (FAQs) Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation: Questions and Answers about these Adult/NONembryonic Stem Cells Key Points Hematopoietic or blood-forming stem cells are. (physiciansforlife.org)
Some in vivo transplantation studies have reported robust (35-50%) levels of transdifferentiation, which makes it unlikely that the results are due to cell fusion events. (i-sis.org.uk)
Other uses of the CFU assay include studying the effects of stimulatory and inhibitory growth factors, screening novel compounds to predict potential toxicity to the hematopoietic system, and testing the effects of various in vitro manipulations (e.g. cell processing, cryopreservation, gene transduction, and transmission) on cellular products used in hematopoietic cell transplantation. (stemcell.com)
These epithelial organoid cultures are genetically and phenotypically extremely stable, allowing transplantation of the cultured offspring of a single stem cell, as well as disease modeling by growing organoids directly from diseased patient tissues (32, 47, 53). (hubrecht.eu)
Allogeneic hematopoietic stem cell transplantation is curative but it requires a histocompatible donor and is associated with significant morbidity and mortality, so it is reserved for severe cases of PNH with aplastic anemia or transformation to leukemia. (medscape.com)
Experimental treatment approaches include vaccines and nonmyeloablative allogeneic peripheral blood stem cell transplantation. (medscape.com)
Recent news of an impending clinical cell transplantation trial in Parkinson's disease using parthenogenetic stem cells as a source of donor tissue have raised hopes in the patient community and sparked discussion in the research community. (lu.se)
Based on discussions held by a global collaborative initiative on translation of stem cell therapy in Parkinson's disease, we have identified a set of key questions that we believe should be addressed ahead of every clinical stem cell-based transplantation trial in this disorder. (lu.se)

Scientists have found a way to possibly avoid using embryonic stem. (scitizen.com)
Scientists cloned another Jersey calf using the same "standard cell-culturing techniques as compared to the method most commonly u. (echeat.com)
A protein that is necessary for the formation of the vertebrate brain has been identified by researchers at the Harvard Stem Cell Institute (HSCI) and Boston Children's Hospital, in collaboration with scientists from Oxford and Rio de Janeiro. (scitechdaily.com)
The researchers say the finding, which has been successfully demonstrated in frog embryos, will help scientists control the differentiation of various cell types. (scitechdaily.com)
The induced pluripotent stem cell breakthrough continues to be useful in the very ways that "the scientists" once said only human cloning could provide. (cbc-network.org)
This is terrific but it won't stop "the scientists" from researching human cloning. (cbc-network.org)
Indeed, if every disease known to man were cured by IPSCs or adult stem cells, the scientists would shrug and keep on cloning. (cbc-network.org)
"PrimeGen , based in Irvine, California, says that its scientists have converted specialised adult human cells back to a seemingly embryonic state - using methods that are much less likely to trigger cancer than those deployed previously. (cbc-network.org)
The company also claims to be able to produce reprogrammed cells faster and much more efficiently than other scientists. (cbc-network.org)
Dolly, a Finn Dorset sheep, was introduced to the public in 1997 after scientists at the Roslin Institute at the University of Edinburgh in Scotland implanted the cell nucleus from a sheep into an egg that was subsequently fertilized to create a clone. (pewresearch.org)
1 No one has ever cloned a human being , though scientists have cloned animals other than Dolly , including dogs, pigs, cows, horses and cats. (pewresearch.org)
Now, for the first time, scientists have identified a specific molecular pathway within cells that becomes mutated by ultraviolet light exposure, thereby speeding up melanoma development. (scienceblog.com)
Scientists from the Monash Institute of Medical Research (MIMR) and colleagues from New South Wales will compare two different methods of creating patient-specific stem cells: somatic cell nuclear transfer (SCNT) and induced pluripotent stem cells (iPS). (medicalxpress.com)
Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
Example: In Japan, scientists have discovered the chemical that induces bone marrow to produce healing cells. (nationalrighttolifenews.org)
The chemical which summons stem cells from bone marrow to the site of a wound has been discovered by scientists in the UK and Japan. (nationalrighttolifenews.org)
Scientists at Osaka University and King's College London gave mice bone marrow cells that glow green - which can be tracked while moving round the body. (nationalrighttolifenews.org)
1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)
The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)

The resulting cells were pluripotent and could be differentiated into insulin-producing beta cells to restore the function of the pancreas in the donor. (news-medical.net)
Prior to SCNT, the somatic cell (differentiated) must be reprogramed to a similar state of a pluripotent embryonic cell (undifferentiated) before the nucleus is extracted and transferred. (sibi.org)
Right now, the hottest area in stem cell biology is that of induced pluripotent stem cells, or iPS cells, which have the ability to develop into several different tissue types. (cbc-network.org)
With the announcement last November that Ian Wilmut, who cloned Dolly the sheep, was ditching cloning in favor of the "amazingly efficient" method of induced pluripotent stem-cell research (iPS) - which reprograms adult stem cells into embryonic ones without using human embryos or eggs - pro-lifers had reason to celebrate. (crisismagazine.com)
His new method, known as induced pluripotent stem cells (IPS) , added chemicals to adult cells for about 50 days. (zmescience.com)
While human induced pluripotent stem cells (hiPSCs) provide novel prospects for disease-modeling, the high phenotypic variability seen across different lines demands usage of large hiPSC cohorts to decipher the impact of individual genetic variants. (frontiersin.org)
The advent of the human induced pluripotent stem cells (hiPSCs) technology offers unprecedented opportunities for disease modeling, personalized medicine, and the development of new therapeutic interventions. (frontiersin.org)
Meanwhile, on the IPSC [induced pluripotent stem cells] front, [Dr. Shinya] Yamanaka-who refused to use embryonic stem cells because he saw his own children in them-has increased the efficiency of a method of creating pluripotent stem cells that don't appear to cause tumors. (nationalrighttolifenews.org)
The proliferation and differentiation of pluripotent stem cells give rise to progeny that can populate the entire immunologic and hematopoietic systems through committed progenitors of both the lymphoid and myeloid lineages. (medscape.com)
Chad and I have both been principal investigators on the induced pluripotent stem cell (IPSC) grant. (medscape.com)
I fell in love with the idea of human pluripotent stem cells and started surveying the United States and even Europe for who was playing in that area. (medscape.com)

Pro-cloning forces have been working hard to convince state governments to pass constitutional amendments enshrining a "right" to clone and to destroy embryos for research. (flfamily.org)
The legislation, which bans reproductive cloning as well as embryonic stem cell research in which human life is destroyed, was amended in the House last week to outlaw the cloning process to create human embryos for research, but would allow importation of embryonic stem cell lines created outside the state for research. (lifenews.com)
Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)

But, although the mutation frequency of genes was much lower in ES cells, mutant ES cells accumulated with time in culture. (i-sis.org.uk)
Two separate research teams have figured out how to "reprogram" cells with just a handful of genes to give them the characteristics of embryonic stem cells. (nih.gov)
The egg then "reprograms" the adult nucleus so that the cell behaves like an embryo but has the genes of the adult cell. (nih.gov)
Amongst the intestinal Wnt target genes (13), we found the Gpr49/Lgr5 gene to be unique in that it marks small cycling cells at crypt bottoms. (hubrecht.eu)
Two other Wnt target genes, RNF43 and ZNRF3, encode stem cell-specific E3 ligases that downregulate Wnt receptors in a negative feedback loop (35). (hubrecht.eu)
The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
The precise pathophysiology of inherited single cell and multilineage cytopenias has not been elucidated despite the identification of many of the genes mutated in these disorders. (medscape.com)
Myelodysplastic syndromes are a group of clonal hematopoietic stem cell disorders unified by the presence of distinct mutations of hematopoietic stem cells, most frequently in genes involved in RNA splicing. (msdmanuals.com)
Genetic studies of the families at high risk for developing renal cancer led to the cloning of genes whose alteration results in tumor formation. (medscape.com)
explosion further, consider that a fictitious small genome with 2002) More recently and more dramatically, the potential for 260 genes would host the same number of combinations as cell state conversions is exemplified by the reprogramming of the number of atoms in the visible universe! (lu.se)

This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
Twenty years have passed since Dolly the sheep was born by cloning (somatic cell nuclear transfer, SCNT) but the results of non-human mammalian cloning are very poor, and cause animal diseases and huge biological losses. (sibi.org)
Researchers have been hoping to harness the therapeutic potential of cloning ever since the cloning of Dolly the sheep in 1997. (nih.gov)
When an embryo like this is implanted into a uterus, as with Dolly, the process is called reproductive cloning. (nih.gov)
Still, a majority of adults (60%) say cloning animals like Dolly is morally wrong, compared with 34% who say it's morally acceptable. (pewresearch.org)
Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
This led to the creation of Dolly the cloned sheep . (zmescience.com)

Paul Wagle, M.A., discusses his experience with a life-saving adult stem cell treatment, and the importance of promoting ethical approaches to medical research. (flfamily.org)
CLI's Vice President and Research Director, Dr. David Prentice, recently joined Molly Smith, host of From the Median, to explain the science, history, and politics of stem cells. (flfamily.org)
Often aborted babies are harvested for Stem Cell Research. (archdiocese-no.org)
The petition recognizes that many "Canadians suffer from debilitating illnesses and diseases" and that the petitioners "support ethical stem cell research that has already shown encouraging potential to provide cures and therapies for these illnesses and diseases. (lifesitenews.com)
In January 2006, Hwang's home research institution, Seoul National University, delivered a damning report about Hwang's work on cloned human embryos, concluding it was all based on fraudulent data. (nature.com)
A chronology of Woo Suk Hwang's stem-cell research. (nature.com)
8 Feb, 2008 06:09 pm Six years ago, biomedical engineer Michael King was exploring the strange rolling motion of white blood cells when his research took a radical turn. (scitizen.com)
27 Nov, 2007 10:41 am Tony Maciulis talks with Dr. Jon LaPook about a breakthrough in stem cell research. (scitizen.com)
21 Nov, 2007 10:54 am A huge advancement in stem cell research--and a stake in the heart of human cloning--was announced yesterday. (scitizen.com)
6 Sep, 2007 12:57 pm British authorities decided yesterday to permit research that uses animal eggs to create human stem cells because of the limited supply of human eggs. (scitizen.com)
25 Jun, 2007 04:43 pm On June 7, the House of Representatives voted 247-176 to pass a bill (S 5) that would allow federal funding for research using stem cells derived from. (scitizen.com)
Prior to September 11, the defining moment of the Bush presidency had been the president's decision to limit embryonic stem-cell research. (breakpoint.org)
Along the same lines, a writer in the Baltimore Chronicle accused "opponents of embryonic stem-cell research" of "prolonging the suffering of millions. (breakpoint.org)
He labeled the president, and other opponents of embryonic stem-cell research, as an "obstacle to hope for a scientific breakthrough, a miracle. (breakpoint.org)
Reeve, who was left paralyzed after being thrown from a horse a decade ago, was a tireless advocate of embryonic stem-cell research. (breakpoint.org)
Second, the policy applies only to research using federal money for embryonic stem-cell research. (breakpoint.org)
Federally funded research can be conducted using stem cell lines that were already available in August 2001. (breakpoint.org)
In other words, the author relates legislation that allows for human cloning to take place in a research realm, as long as no clon. (echeat.com)
For those trying to create neural cells, "Notum is a necessary ingredient and new tool in the kit box for researchers to instruct human progenitor cells to become neural tissues," said He, who is also an American Cancer Society research professor. (scitechdaily.com)
Britain s House of Lords final approval of therapeutic human cloning and embryonic stem cells research has intensified the battle for ascendancy between adult and embryonic stem cells. (i-sis.org.uk)
The scenario is an open public hearing of a research ethics committee, to decide on granting a licence for a clinical trial using human embryonic stem cells to treat spinal cord injuries. (eurostemcell.org)
Participants role play members of the committee and different stakeholders in the audience, and in doing so engage in debates on the scientific and social issues surrounding stem cell research. (eurostemcell.org)
to involve people in the debates on the scientific and social issues surrounding stem cell research. (eurostemcell.org)
After completing the role play, participants should have a better understanding of the basic scientific concepts underlying stem cell research. (eurostemcell.org)
However, the main objective of this resource is to be an exploration of the social issues around stem cell research. (eurostemcell.org)
Why use embryos for stem cell research? (eurostemcell.org)
May this type of research make human cloning more likely? (eurostemcell.org)
I would recommend this role play as it gave me an insight into the application for a clinical trial process and background into stem cell research. (eurostemcell.org)
In a meeting in Washington (3 December 2001) the researcher Tanja Dominko presented the results of monkey cloning (Macacus rhesus) when she worked at the Regional Center of Research in Primates of Beaverton, Oregon (USA). (sibi.org)
Remember, this is the research which takes and adult skin cell and then turns the stem cells back to an "embryonic" like state. (cbc-network.org)
Keep in mind, this is ethical adult stem cell research, which is in human clinical trials, helping patients NOW. (cbc-network.org)
Unlike *yawn* embryonic stem cell and cloning research which has produced zip to date. (cbc-network.org)
Current Research and Scholarly Interests Recent clinical studies, by us and others, have demonstrated that genetically engineered T cells can eradicate cancers resistant to all other therapies. (stanford.edu)
In a 2010 Pew Research Center survey , 48% of adults said that a human being would definitely or probably be cloned by 2050, compared with 49% who said such an event would not happen. (pewresearch.org)
In a 2013 Pew Research Center poll , half of all adults surveyed (50%) said that by 2050 researchers will be able to use cloning to bring back extinct species, with 48% predicting such a development won't occur. (pewresearch.org)
However, there is hope for the future as Governor Kathleen Blanco told pro-life advocates that she does not support embryonic stem cell research, and favors the wholesale cloning bans that pro-life organizations had backed. (lifenews.com)
Governor Blanco discussed the bills with the Louisiana Coalition for Ethical Stem Cell Research on the final day of the session, and said that bills banning reproductive cloning but allowing for destructive embryonic research, such as the one sponsored by Senate President Don Hines (D-Bunkie), would not receive her support. (lifenews.com)
The two other cloning bans, both wholesale bans that would have prohibited the destructive research, overcame many obstacles to come close to passage, and eventually garnered the support of a majority of the legislature. (lifenews.com)
Finally, the cloners see that there is no political stability for their clone and kill labs in Louisiana, meaning that effective adult stem cell research can continue to thrive in Louisiana," concluded Bordlee. (lifenews.com)
Rep. Beard had pointed out that a total human cloning ban does not impede research, as his opponents, including Senator Hines, have accused. (lifenews.com)
During debate on his bill, Beard stated that opponents of his bill place a 'false hope' in embryonic stem cell research. (lifenews.com)
As of yet no useful embryonic stem cell lines have been created, and all breakthroughs in stem cell research have been done with adult stem cells, which do not require the destruction of human life. (lifenews.com)
We want real cures now available from ethical adult stem cell research, not illusory promises from unproductive embryo research,' the Louisiana Coalition for Ethical Stem Cell Research said in a statement. (lifenews.com)
Victoria and New South Wales have put aside their competitive interstate rivalry to collaborate on a stem cell research project, as announced by Innovation Minister Gavin Jennings and NSW Minister for Science and Medical Research, Verity Firth, today. (medicalxpress.com)
Mr Jennings said changes to the Victorian Infertility Treatment Act and the NSW Human Cloning and Other Prohibited Practices Act have opened up new opportunities for stem cell research in Australia. (medicalxpress.com)
Australia is already a global leader in overall stem cell research and this new and clear regulatory framework gives us an opportunity to extend our leadership into SCNT which could transform how we treat diabetes, heart diseases and Parkinson's," Mr Jennings said. (medicalxpress.com)
Pro-lifers fumed during the 2004 presidential race when John Kerry attacked opponents of embryonic stem-cell (ESC) research as "anti-science" ideologues who sought to block life-saving cures "right at our fingertips. (crisismagazine.com)
In a 2012 letter to Children of God for Life, PepsiCo stated that "Senomyx does not use HEK cells or any other tissues or cell lines derived from human embryos or babies for research performed on behalf of PepsiCo. (hli.org)
No harm comes to the person whose stem cells are obtained for research in such a fashion. (all.org)
There are those in the government and scientific community who say more money must be spent on human embryonic stem cell research because it holds the most promise for helping people with conditions such as Alzheimer's disease. (all.org)
Alzheimer's researcher Ned Potter said, however, that human embryonic stem cell research would not help the Alzheimer's patient at all. (all.org)
Contrary to the impression many people have, research involving human embryonic stem cells is not new. (all.org)
Yet, human embryonic stem cell research has thus far been unsuccessful in the quest to develop any therapeutic treatments. (all.org)
Therefore, it is speculated that those who support human embryonic stem cell research are clamoring loudly for taxpayer dollars because private companies know human embryonic stem cell research is neither worth their time nor their money. (all.org)
On the other hand, research involving adult stem cells has not only been around for a long time, it has also been used successfully for decades! (all.org)
It is further speculated that those who support human embryonic stem cell research are also seeking human embryos for the purposes of human cloning. (all.org)
While stem cell research and human cloning are complex topics, the facts are readily available. (all.org)
On the issue of stem cell research, the gap between the scientific and religious cultures has never been wider. (prospect.org)
The potential of stem cell research to enhance human life is extraordinary. (prospect.org)
Should expensive therapies derived from stem cell research be covered universally by health insurance? (prospect.org)
He decreed that stem cell colonies produced before Aug. 9, 2001, could continue to receive federal funding for research purposes but no federal money could go to develop new stem cells from embryos. (prospect.org)
The life-enhancing promise of stem cell research is just too potent and the ethical questions too tricky to leave the issue in the hands either of private entrepreneurs or religious fundamentalists, much less both. (prospect.org)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
This paper outlines the debates prompted through a reproduction mechanism involv- by progress in cloning research, with special ing male and female germ cells. (who.int)
At International Society for Stem Cell Research-the big stem cell meeting-Yamanaka revealed one more factor. (medscape.com)

8 Jun, 2007 04:13 pm Stem cells provide the starting material for the development and repair of every organ and tissue in the body and they are present in all stages of life. (scitizen.com)
These findings could benefit stem cell researchers trying to create specific tissue types or organs in the lab. (scitechdaily.com)
Two reports appeared as advance online publications in the top British journal Nature , accompanied by a news report that begins, "The hyped ability of adult stem cells to sprout replacement tissue types is being called into question. (i-sis.org.uk)
What about tissue (adult) stem cells? (eurostemcell.org)
Equine mesenchymal stem cells from bonemarrow, adipose tissue and umbilical cord:immunophenotypic characterization anddifferentiation potential. (sciendo.com)
Osteogenic proliferation and differentiation of canine bone marrow and adipose tissue derived mesenchymal stromal cells and the influence of hypoxia. (sciendo.com)
Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stem Cells from Sheep: Culture Characteristics. (sciendo.com)
With the right mix of nutrients and a little bit of coaxing, human stem cells derived from skin can assemble spontaneously into brain-like chunks of tissue. (cbc-network.org)
The researchers found that tissue chunks cultured from stem cells derived from the skin of a single human with microcephaly did not grow as big as clumps grown from stem cells derived from a healthy person. (cbc-network.org)
They traced this effect to the premature differentiation of neural stem cells inside the microcephalic tissue chunks, depleting the population of progenitor cells that fuels normal brain growth. (cbc-network.org)
CD34 is a transmembrane phosphoglycoprotein that was first identified on HSPCs, but its expression is also present on other cell types, such as vascular tissue. (stemcell.com)
The accomplishment, known as hematopoietic transdifferentiation, may prove useful for tapping the potential for tissue repair using human adult stem cells. (scienceblog.com)
The Organoid group, previously Clevers group, studies the molecular mechanisms of tissue development and cancer of various organs using organoids made from adult Lgr5 stem cells. (hubrecht.eu)
These cells represent the epithelial stem cells of the small intestine and colon (23), the hair follicle (24), the stomach (28) and many other tissue stem cell types. (hubrecht.eu)
XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
Obtaining stem cells from fatty tissue, bone marrow, or the umbilical cord after the birth of a baby, on the other hand, may be done ethically. (all.org)
He explained that the early embryonic cells that his laboratory tries to turn into specialized tissue for therapeutic purposes hadn't even ''individuated'' yet. (prospect.org)
One of the greatest controversies triggered tissue, a stem cell encoding for heart tissue by the rapid pace of evolution in biology, will eventually develop into heart tissue particularly in genomics and biotechnology, and so on. (who.int)
The tissue of origin for renal cell carcinoma (RCC) is the proximal renal tubular epithelium. (medscape.com)

27 Jun, 2007 06:08 pm Stem cells have the potential to become all the cells and tissues in the human body. (scitizen.com)
Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
They may instead be fusing with existing cells, creating genetically mixed-up tissues with unknown health effects" [1]. (i-sis.org.uk)
Comparison of human mesenchymal stromal cells from four neonatal tissues: Amniotic membrane, chorionic membrane, placental decidua and umbilical cord. (sciendo.com)
But, he adds, the study also demonstrates the potential for using human-stem-cell-derived tissues to model other disorders, if cell growth can be controlled more reliably. (cbc-network.org)
In mammals, physiological Wnt signaling is intimately involved with the biology of adult stem cells and self-renewing tissues (18,19). (hubrecht.eu)
Moreover, the field is only inching forward scientifically as it is proving very hard to harness cells meant to create differentiated tissues in gestating embryos and fetuses. (nationalrighttolifenews.org)
Somatic base substitution mutation rates in intestinal epithelial cells were elevated 2 to 4-fold in all individuals, except for one showing a 31-fold increase, and were also increased in other tissues. (bvsalud.org)

Dolly's debut set off a firestorm about both the practical value and ethics of cloning, including the possibility of human cloning. (pewresearch.org)
I recently participated in a debate at the Harvard Medical School on the ethics of stem cell cloning. (prospect.org)

Somatic cell nuclear transfer (SCNT) is a type of cloning that has to be done in a lab. (bartleby.com)
In SCNT they take the nucleolus out of an egg cell, replace it with the nucleolus of a somatic cell (body cell with two complete sets of chromosomes), and make the egg cell divide into a blastocyst ("What Is Cloning? (bartleby.com)
One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
Using eggs from adult women who had previously donated for successful fertility treatments, the researchers used SCNT to transfer DNA into the egg cells. (the-scientist.com)
I believe that the reprogramming errors are not the only cause of these low rates of cloning: the mammalian SCNT fails with a very high frequency mainly due to the damage that the technique itself inflicts in the egg and the somatic nucleus, and the very few successful cases occur only when the damage is not significant. (sibi.org)
True cloning performed by nuclear transfer from an adult and differentiated somatic cell to a previously enucleated egg (somatic cell nuclear transfer, SCNT), gives rise to a new cell, the nuclovulo (nucleus+ovum), distinct from the zygote because the sperm is not involved in its creation, while both can develop as embryos and give rise to offspring. (sibi.org)
체세포 핵 치환 (Somatic-cell nuclear transfer, SCNT)은 난자 의 핵 을 제거한 후에, 체세포 의 핵을 이식하여 복제 를 하는 기술을 말한다. (wikipedia.org)
SCNT, or therapeutic cloning, is one method used to produce a source of individually-tailored stem cells. (medicalxpress.com)
One aspect to this project will be to source oocytes, or immature egg cells to generate SCNT embryos from which embryonic stem cells are harvested. (medicalxpress.com)
Unlike SCNT, iPS cells are derived from adult cells, such as skin, which are reprogrammed to behave like embryonic stem cells. (medicalxpress.com)
Once our team produces the iPS cells, we will compare the properties of iPS versus cells developed through SCNT. (medicalxpress.com)

By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)
genetically superior clone set. (echeat.com)
In another strategy, called therapeutic cloning, the embryo can instead be used to create stem cells that are genetically identical to a patient. (nih.gov)
Before this new study was published, Nature asked another group of researchers to confirm that the stem cells were genetically identical to the donor skin cells. (nih.gov)
Researchers in North Carolina have successfully demonstrated that genetically altered stem cells from one species can be turned into a different sort of cell in another. (scienceblog.com)
Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)
There are differences-so much so that despite the "exact copy" claim, the cloned organism is actually unique genetically. (all.org)

Kass calls it "cruel to suggest that stem-cell-based therapies are 'at our fingertips. (breakpoint.org)
These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)
We are identifying new targets for these therapeutics, exploring pathways of resistance to current cell therapies and creating next generation platforms to overcome therapeutic resistance. (stanford.edu)
At the same time, labs in a variety of countries have successfully cloned human embryos for the purpose of producing stem cells that can be used in medical therapies. (pewresearch.org)
Ex vivo manufactured red blood cells (RBC) generated from immortalized erythroid cell lines which can continuously grow are expected to become a significant alternative in future transfusion therapies. (lu.se)
Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016? (lu.se)
Stem cell-based therapies for Parkinson's dis- ogy company International Stem Cell Corporation ease (PD) are rapidly moving towards clinical trials. (lu.se)

Accelerated hematopoietic cell apoptosis has been demonstrated in virtually all IBMFS. (medscape.com)

2017). MMP-2 and MMP-14 Silencing Inhibits VEGFR2 Cleavage and Induces the Differentiation of Porcine Adipose-Derived Mesenchymal Stem Cells to Endothelial Cells. (sciendo.com)
The colony-forming unit (CFU) assay is a clonal, in vitro culture assay that measures the growth and frequency of functionally viable HSPCs by assessing the proliferation and differentiation of individual progenitor cells, resulting in the formation of discrete colonies in a semi-solid methylcellulose medium (such as MethoCult™ ) when supplemented with appropriate cytokines. (stemcell.com)
Cell markers, or surface antigens, are molecules located on a cell's membrane used to identify specific cell types, their lineage, and their stage in the differentiation process according to the presence or absence of the expression of defined markers. (stemcell.com)
To induce differentiation and maturation of the immortalized cell lines, terminating the HPV-E6/E7 expression through a gene induction system has been believed to be essential. (lu.se)
Here, we report that erythroid cell lines established from human bone marrow using simple expression of HPV-E6/E7 are capable of normal erythroid differentiation, without turning gene expression off. (lu.se)
Our findings propose that it is not necessary to employ gene induction systems to establish immortalized erythroid cell lines sustaining differentiation potential and describe novel cellular characteristics for desired functionally competent clones. (lu.se)
Various biological events associated with bone healing on implant surfaces can be investigated separately using appropriate cell cultures, such as cell adhesion, proliferation and differentiation, as well as the production and mineralization of extracellular matrix. (bvsalud.org)
Stem and progenitor cell populations are often heterogeneous, which may reflect stem cell subsets that express subtly different properties, including different propensities for lineage selection upon differentiation, yet remain able to interconvert. (lu.se)
A key challenge is to understand how state, but must also afford flexibility in cell-fate choice to permit the different cell-fate options confronting stem and progenitor cell-type diversification and differentiation in response to cells are selected and coordinated such that adoption of a given intrinsic cues or extrinsic signals. (lu.se)
Evidence the fate of stem cells has broad ramifications for biomedical suggests that during development or differentiation, cells make science from elucidating the causes of cancer to the use of very precise transitions between apparently stable ``network stem cells in regenerative medicine. (lu.se)

Elaboration of an international convention against reproductive cloning of human beings has been under consideration in the United Nations since December 2001 when the subject was included in the agenda of the fifty- sixth session as a supplementary agenda item at the request of France and Germany. (who.int)
2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)

General Assembly the following year,3 and the World Medical Association's Resolution on Cloning, endorsed in 1997, have confronted the issue but lack binding legal force. (who.int)
WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)

We have discovered novel insights into the biology of human T cell exhaustion and developed approaches to prevent and reverse this phenomenon. (stanford.edu)
Dr Paul Verma, Program Leader of MIMR's Stem Cell Biology Program and the Chief Investigator of the Victorian project team, will create the iPS cells for this project. (medicalxpress.com)
We were the first to link Wnt signaling with adult stem cell biology, when we showed that TCF4 gene disruption leads to the abolition of crypts of the small intestine (8), and that TCF1 gene knockout severely disables the stem cell compartment of the thymus (2). (hubrecht.eu)
Understanding cell-fate decisions in stem cell populations is a major goal of modern biology. (lu.se)

Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell (HSC) disease. (medscape.com)

18 Sep, 2007 12:13 pm Rice University researchers have engineered musculoskeletal cartilages with human embryonic stem cells, with the hope of eventually using the neotissue. (scitizen.com)
6 Jun, 2007 07:00 pm Researchers have reprogrammed skin cells into embryonic stem cells. (scitizen.com)
There is nothing in the policy that stops researchers from using stem cells obtained elsewhere, like adult stem cells. (breakpoint.org)
Researchers from the Harvard Stem Cell Institute have identified a vital protein that can help determine embryonic development. (scitechdaily.com)
In order to guide or direct stem cells to differentiate into a given cell type, such as neural cells or muscle cells, researchers continue to alter their experimental recipes, fine-tuning which molecules should be added to their dishes in what sequence and amount. (scitechdaily.com)
Additionally, the researchers were able to demonstrate how Notum deactivates Wnt, which is a family of proteins that direct stem cells to "self-renew," or make more stem cells, among other things. (scitechdaily.com)
A linkurl:report;http://stemcells.alphamedpress.org/cgi/reprint/2007-0252v1.pdf published online today that researchers have cloned human embryos is not that much of an advance, according to one stem cell expert, Douglas Melton, at Harvard University. (the-scientist.com)
In the first report [2], researchers from Edinburgh and Oxford took cells from the mouse brain marked with transgene 1, and cultured them together with ES cells marked with a second transgene, 2. (i-sis.org.uk)
These researchers pointed out that the spontaneous fusion rate (without interleukin-3) was extremely low, between 2-11 per million bone marrow cells, and is unlikely to account for all the findings with adult stem cells. (i-sis.org.uk)
Researchers reported in Nature on November 22, 2007, that they successfully isolated 2 embryonic stem cell lines from cloned embryos made using cells from the skin of an adult rhesus macaque. (nih.gov)
The stem cells, the researchers showed, could turn into heart or nerve cells in the laboratory, and had other characteristics of established embryonic stem cell lines. (nih.gov)
Specifically, the researchers converted adult liver stem cells cloned from a male rat into functional adult bone marrow cells in female mice. (scienceblog.com)
UK researchers have rejuvenated the skin cells of a 53-year-old woman so they are the equivalent of a 23-year-olds. (zmescience.com)
The technique used by Reik and his team comes from the 1990s when researchers from the Roslin Institute found a way to turn an adult mammary gland cell taken from a sheep into an embryo. (zmescience.com)

Haematopoietic stem cells or multipotent progenitors (HSC/MPPs) accumulated a mean of 17 mutations per year after birth and lost 30 base pairs per year of telomere length. (bvsalud.org)

The heated debate in our society over reproductive cloning, as well as therapeutic cloning to obtain embryonic stem cells, has been fueled by misconceptions and hyperbole on both sides. (flfamily.org)
These cells have been described as embryonic stem cells (ESCs) and. (scitizen.com)
The president's policy affects only embryonic stem cells. (breakpoint.org)
And the federal policy doesn't prohibit the use of all embryonic stem cells. (breakpoint.org)
Embryonic stem cells are immortal, and have the potential to develop into any type of adult cell, even after months growing in culture dishes. (news-medical.net)
They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
Dermal fibroblasts were taken from a 35-year old male and a 75-year-old male and used to create embryonic stem cells. (news-medical.net)
The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
Although attempts have not yet been made to create a therapeutic transplant from embryonic stem cells, the methods have been developed to allow the creation of functional, mature cells using human cell cloning technology. (news-medical.net)
of these embryonic stem cells left and the adult stem cells are just not as promising. (echeat.com)
This latest anti-publicity on adult stem cells comes on the heels of a paper announcing success in embryonic stem (ES) cell transplant in a Parkinson rat model published in the house journal of the United States National Academy of Sciences [5]. (i-sis.org.uk)
Since embryonic stem cells have the ability to form virtually any cell type in the body, those taken from a cloned embryo could potentially be used to treat many diseases. (nih.gov)
The team that isolated the embryonic stem cell lines was led by Dr. Shoukhrat Mitalipov at Oregon Health and Science University in Portland. (nih.gov)
On paper, iPS cells appear to be a preferable alternative to working with human embryonic stem cells, but it's too early to make this assumption. (medicalxpress.com)
If we can overcome this, they could certainly offer a great alternative to embryonic stem cells. (medicalxpress.com)
Professor Tuch's team will also use their proficiencies in characterising human embryonic stem cell lines and bioinformatics. (medicalxpress.com)
However, their real aim was to create so-called human embryonic stem cells to replace worn-out body parts. (zmescience.com)
They were surprised to find that the cells didn't turn into embryonic stem cells as in the previous study by Yamaka. (zmescience.com)
The injection or infusion of embryonic stem cells are not the ones needed. (all.org)
Dr. Shinya Yamanaka of Japan and others have turned adult skin cells into human embryonic stem cells, without using an embryo. (nationalrighttolifenews.org)
The days of embryonic stem cells as "the only hope" are long gone. (nationalrighttolifenews.org)
Regardless of how well read you are on the embryonic stem cell debate, I think you will find Brahm's treatment to be accessible and informative. (alexchediak.com)
2005). Notch1 and syndecan-1 potent human embryonic stem (ES) cells. (lu.se)
We discuss these properties with examples both from the hematopoietic and embryonic stem cell (ESC) systems. (lu.se)

They found that the spontaneous mutation frequency in ES cells is 100-fold lower than that in mouse embryonic fibroblasts (a somatic cell line), which is similar to adult cells in vivo . (i-sis.org.uk)
2018). Development of bovine embryos in vitro in coculture with murine mesenchymal stem clls and embryonic fibroblasts. (sciendo.com)
The microenvironment, consisting of lymphocytes, macrophages, fibroblasts, endothelial elements, and stroma in which hematopoietic cells reside, creates a regulatory niche that determines the local area network. (medscape.com)
Human CMV grows only in human cells and replicates best in human fibroblasts. (medscape.com)
2008). Historically, this concept is highlighted by the experi- factors are key intrinsic regulators of these fate decisions and mental phenomenon of lineage reprogramming, for example, that fate choice involves modulating networks of transcription by the conversion of fibroblasts to muscles cells following trans- factors. (lu.se)

There has been overwhelming opposition to human cloning since 2001. (pewresearch.org)

He added that treatments for dreaded diseases "could be right at our fingertips" if we lifted "the stem cell ban. (breakpoint.org)
However, the use of stem cells to treat diseases is still extremely limited in the present day. (zmescience.com)
There are more than 70 diseases or conditions-including leukemia, immune system and other blood disorders, cancers, and autoimmune diseases-that respond well when adult stem cell therapy is used. (all.org)
2. Omitting that the diseases everyone is talking about curing (diabetes, Parkinson's, paralysis) have already been treated with adult stem cells. (alexchediak.com)
Any person or institution that provides vaccination services should adopt these standards to improve vaccination delivery and protect infants, children, adolescents, and adults from vaccine-preventable diseases. (cdc.gov)

CD34 is the most commonly used cell surface marker to identify human HSPCs as it is expressed on HSCs, in addition to both multipotent and more differentiated progenitor cells of individual blood cell lineages. (stemcell.com)
Lgr6 marks multipotent skin stem cells (29). (hubrecht.eu)

Retrieved on December 04, 2023 from https://www.news-medical.net/life-sciences/Cloning-Human-Cells.aspx. (news-medical.net)

Neither report cited a paper published last year in the journal Blood [4], where a group from the Stem Cell Institute, Department of Medicine, and Cancer Center, University of Minnesota Medical School, Minneapolis, reported the most comprehensive experiments proving that a single adult stem cell can differentiate into all cell types in culture. (i-sis.org.uk)
The cells could be made to differentiate into bone forming cells, cartilage forming cells, fat cells, skeletal muscle cells and endothelial cells. (i-sis.org.uk)
The have been applied to both the plant and ani- stem cells possess pluripotential charac- mal kingdoms without even stirring a ripple teristics, and can differentiate into various of concern in international conscience [ 2 ]. (who.int)
Through simply changing cell culture conditions, a newly established cell line, Erythroid Line from Lund University (ELLU), is able to differentiate toward mature cells, including enucleated reticulocytes. (lu.se)
ELLU is heterogeneous and, unexpectedly, clones expressing adult hemoglobin rapidly differentiate and produce fragile cells. (lu.se)

The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)

The Ethical Debate Concerning Cloning In the year that has elapsed since the announcement of Dolly's birth, there has been much discussion of the ethical implications of cloning humans. (bartleby.com)
However, the idea of cloning humans is a highly charged topic. (bartleby.com)
3 Americans are divided as to whether humans will be cloned in the near future. (pewresearch.org)
5 Fewer Americans are concerned with cloning animals than with the prospect of cloning humans , according to the same 2016 Gallup survey . (pewresearch.org)
The intent of this legislation is to prevent the cloning of humans,' said Rep. Beard. (lifenews.com)
2002). In humans, SSEA4 is expressed by building the nervous system but also for their prospec- nonneural cells such as the erythrocytes (Kannagi et al. (lu.se)

Another argument in favor of animal cloning is that which relates to products. (echeat.com)
Common myths about immoral clones and a world full of exact duplicates are refuted in this paper, which argues in favor of continu. (echeat.com)

Within a few years, unless the religious right manages to stop it, specialized cells developed from either embryonic or adult cells will be used therapeutically to treat everything from Parkinson's, Alzheimer's, diabetes, spinal injuries, heriditary impairments, and even the regeneration of diseased organs. (prospect.org)
In this article, we first provide a short history of cell therapy in Parkinson's disease and briefly describe the current state-of-art regarding human stem cell-derived dopamine neurons for use in any patient trial. (lu.se)
With this background information as a foundation, we then discuss each of the key questions in relation to the upcoming therapeutic trial and critically assess if the time is ripe for clinical translation of parthenogenetic stem cell technology in Parkinson's disease. (lu.se)

Those were spindle removal, donor cell fusion, and cytoplast activation. (news-medical.net)
The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)

Cryopreserved allogeneic mesenchymal stem cells enhance wound repair in full thickness skin wound model and cattle clinical teat injuries. (sciendo.com)

We're thrilled to have Chad Cowan, an associate professor at Harvard University who is at the Harvard Stem Cell Institute. (medscape.com)

The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)
Cloning entails taking the nucleus - the compartment that contains the DNA - from an adult cell and putting it into an egg from which the original nucleus has been removed. (nih.gov)
The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)
When the nucleus of a stem cell has been the technique of cloning. (who.int)
The basic techniques of of the implanted nucleus, when it fully cloning have been known for some time, and develops. (who.int)

Several authors have attempted to outline some of the ethical objections to cloning while at the same time minimizing the role religion plays in this debate. (bartleby.com)
The finding that adult cells can fuse with ES cells is therefore irrelevant to the debate, and the fact that it was used in an attempt to discredit adult stem cells is itself revealing, particularly in view of other recent findings on ES cells. (i-sis.org.uk)
This cell then has therapeutic cloning: the global the capacity to divide and grow into an exact replica of the original from whom the debate somatic cell was taken. (who.int)

Reproductive cloning is performed with the express intent of creating another organism. (echeat.com)
… "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)
The science fiction definition of "clone" suggests that the cloned organism would be an exact genetic copy of another creature-human or beast-created in the laboratory by any of a number of means. (all.org)
A clone is an organism that is a genetic copy of an existing one. (who.int)

Cloning: Do we even need eggs? (nature.com)
Should women be paid to donate eggs or fertilized embryos to stem cell labs? (prospect.org)

Do our only cloned primates come from the lab of Woo Suk Hwang's colleague? (nature.com)
Their report, published in the same issue of the journal, confirms that therapeutic cloning has now been accomplished in primates for the first time. (nih.gov)
Although this study proves that the therapeutic cloning of primates is possible, there are still many hurdles to be overcome. (nih.gov)

A type of cloning that occurs naturally is when identical twins are born ("What Is Cloning? (bartleby.com)
it will naturally not be long before we actively clone people as complete entities. (echeat.com)

The Tcf4-driven target gene program in colorectal cancer cells is the malignant counterpart of a physiological gene program in selfrenewing crypts (13, 14). (hubrecht.eu)
The Wnt target gene encoding the transcription factor Achaete scute-like 2 controls intestinal stem cell state (26). (hubrecht.eu)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
The ectopic expression of human papilloma virus (HPV) E6/E7 gene has successfully been employed to establish these cell lines. (lu.se)
Similarly, GATA-1 has been shown to induce lineage switching expression values even if, for simplicity, we assume only ``on'' of committed cells in hematopoiesis, first in cell lines (Kulessa and ``off'' states for each gene. (lu.se)

Dr. Irving, whose Ph.D. included a doctoral concentration in secular bioethics at the world's foremost bioethics institute, noted that the bill was poorly prepared using faulty science and lacking basic definitions necessary to have the law actually ban cloning as it claims it does. (lifesitenews.com)

The potential of intra-articular injection of chondrogenic-induced bone marrow stem cells to retard the progression of osteoarthritis in a sheep model. (sciendo.com)
HSCs make up a very small population of the hematopoietic system, however, these cells are invaluable as they have the potential to give rise to all mature blood and immune cell types and sustain life-long blood production. (stemcell.com)
Currently, iPS cell lines show variability in their potential to produce mature cells. (medicalxpress.com)
Therapeutic cloning possesses enormous potential for revolutionizing medical and thera- peutic techniques. (who.int)
Cloning technology, however, is perceived as having the potential for reproductive cloning, which raises serious ethical and moral concerns. (who.int)
The biological properties and clinical potential of stem cells elicit that are generated must not be unduly sensitive to small fluctu- continued scientific, commercial, and public interest. (lu.se)

Cellular cloning refers to a process in which "copies of a cell ar. (echeat.com)
When investigating the causes of this failure via cellular and molecular analysis of 2-cell zygotes and the successive cell divisions (blastomeres), all kinds of abnormalities were found. (sibi.org)

Ethical Stem Cell Breakthrough! (scitizen.com)
Now, in what appears to be a very notable breakthrough, they have been used to make patient-specific, tailor made neural cells for study. (cbc-network.org)
The breakthrough may eventually put to rest the ethical controversy surrounding stem cells. (nih.gov)
His announcement a week earlier of a supposed breakthrough in human cloning nearly stampeded the Senate into banning cloning even for therapeutic purposes. (prospect.org)

Adipose stem cells in reparative goat mastitis mammary gland. (sciendo.com)

un tel dialogue prendra en considération non seulement les bienfaits scientifiques mais également les implications morales, éthiques et juridiques. (who.int)

The NSW project team, led by Professor Bernie Tuch, will investigate another method of obtaining oocytes - from consenting adult cancer patients who have had their ovaries removed. (medicalxpress.com)

The rapidly emerging "regenerative" field of medicine is relying heavily on the use of ethically obtained stem cells. (flfamily.org)
WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)

Anatomy27

Organisms5

Chemicals and Drugs15

Analytical, Diagnostic and Therapeutic Techniques and Equipment28

Phenomena and Processes24

Disciplines and Occupations4

Technology, Industry, Agriculture1

Information Science3

Named Groups1

Health Care1

Somatic cells4

Fetal11

Transplantation8

Scientists19

Pluripotent11

Embryos for research3

Genes10

Dolly8

Research65

Tissue19

Tissues8

Ethics2

SCNT15

Genetically8

Therapies7

Hematopoietic cell1

Differentiation10

Reproductive cloning of huma5

19972

Biology4

Clonal hematopoietic stem1

Researchers14

Accumulated a mean of1

Embryonic stem24

Fibroblasts5

20011

Diseases5

Multipotent2

20231

Differentiate5

Therapeutic potential1

Humans6

Favor2

Parkinson's3

Donor4

Mesenchymal stem1

Harvard Stem Cell Institute1

Nucleus5

Debate3

Organism4

Eggs2

Primates3

Naturally2

Gene5

Bioethics1

Potential6

Cellular2

Breakthrough4

Mammary gland1

Implications1

Oocytes1

Ethically2