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  • embryonic stem
  • Because of their plasticity and potentially unlimited capacity for self-renewal, embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. (wikipedia.org)
  • genes
  • The aim was to compare genes expressed by highly and poorly chondrogenic clones to identify genes associated with those MSCs with an enhanced capacity for cartilage formation. (datamed.org)
  • We also show that one of the genes, ey / Pax6 , is expressed in OPC neuroblasts and controls migration of a subpopulation of cells in the optic lobe. (biologists.org)
  • generate
  • White and Kankel, 1978 ), generate the correct number of cells present in the adult optic lobe: the IPC gives rise to neurons of the lobula complex and proximal medulla (presumably cells from the medulla rim), while the OPC generates most medulla neurons (presumably cells from the medulla cortex) as well as cells that will generate the lamina ( Meinertzhagen and Hanson, 1993 ). (biologists.org)
  • while embryonic stem cells can generate all cell types in the body, adult stem cells are multipotent and can produce only a limited number of cell types. (wikipedia.org)
  • Mice
  • Mice cloned from a drop of blood. (wordpress.com)
  • The first one was a female named Cumulina from the cells that surround the developing ovarian follicle in mice. (wikipedia.org)
  • In July 1998 the Yanagimachi laboratory published work in Nature on cloning mice from adult cells. (wikipedia.org)
  • Mice cloned by the Honolulu technique were displayed at the Bishop Museum in Honolulu, Hawaiʻi, and the Museum of Science and Industry in Chicago, Illinois. (wikipedia.org)
  • 1999
  • Hwang's next claim came only two months later in April 1999, when he announced the cloning of a Korean cow, Jin-i, also without providing any scientifically verifiable data. (wikipedia.org)
  • single adult
  • MSC clones were prepared from a single adult human bone marrow sample and screened for their chondrogenic capacity using cartilage tissue engineering (measured by type II collagen content). (datamed.org)
  • humans
  • Even within humans and other mortal species, there are cells with the potential for immortality: cancer cells which have lost the ability to die when maintained in a cell culture such as the HeLa cell line, and specific stem cells such as germ cells (producing ova and spermatozoa). (wikipedia.org)
  • biologist
  • Stem cell biologist George Daley of the Harvard Stem Cell Institute called it "an incremental advance" and "not earth-shattering. (stabroeknews.com)
  • I am a retired cell biologist and alumnus of Ohio State University. (wordpress.com)
  • In 1963 the British biologist J. B. S. Haldane, in describing Gurdon's results, became one of the first to use the word clone in reference to animals. (blogspot.com)
  • surrogate
  • The hybrid cell is then stimulated to divide by an electric shock, and when it develops into a blastocyst it is implanted in a surrogate mother. (wikipedia.org)
  • experiments
  • First of all, most cloning experiments are highly inefficient, meaning that only a few percent of the attempts are ever successful. (wordpress.com)
  • Gurdon began cloning experiments using nonembryonic cells-specifically, cells from the intestinal lining of tadpoles. (blogspot.com)
  • He was a professor of theriogenology and biotechnology at Seoul National University (dismissed on March 20, 2006) who became infamous for fabricating a series of experiments, which appeared in high-profile journals, in the field of stem cell research. (wikipedia.org)
  • Shortly after that his human cloning experiments were revealed to be fraudulent. (wikipedia.org)
  • tissue
  • The 4 most highly chondrogenic and the 4 least chondrogenic MSC clones identified following screening by cartilage tissue engineering were selected for gene array comparison using Affymetrix microarrays. (datamed.org)
  • Tissue engineering - introducing living cells to grow on a framework or synthetic material to produce a tissue eg. (getrevising.co.uk)
  • The term is generally used to refer to artificial human cloning, which is the reproduction of human cells and tissue. (wikipedia.org)
  • According to a 2002 article in PNAS, "Human embryonic stem cells have the potential to differentiate into various cell types, and, thus, may be useful as a source of cells for transplantation or tissue engineering. (wikipedia.org)
  • For example, studies are underway to differentiate ES in to tissue specific CMs and to eradicate their immature properties that distinguish them from adult CMs. (wikipedia.org)
  • germ cells
  • The few that do succeed must actually be true germ cells that exist outside of the sex organs, much like apical meristem in plants. (wordpress.com)
  • Genetic Engineering
  • Nobel Prize-winning geneticist Joshua Lederberg advocated cloning and genetic engineering in an article in The American Naturalist in 1966 and again, the following year, in The Washington Post. (wikipedia.org)
  • eggs
  • He and his colleagues removed skin cells from a 9-year-old macaque and inserted them into eggs from which the original DNA had been removed. (nytimes.com)
  • Dr. Wood and a colleague donated skin cells, and DNA from those cells was transferred to human eggs. (wikipedia.org)
  • Hwang explained that his team used 242 eggs to create a single cell line. (wikipedia.org)
  • Dr. Wood and a colleague donated skin cells and the DNA from those cells was transferred into human eggs. (wikipedia.org)
  • notable
  • Stemagen is a corporation headed by Dr. Samuel Wood, notable for cloning adult skin cells. (wikipedia.org)
  • His alleged success was touted as the fifth instance in the world in cow cloning, with a notable caveat: Hwang failed to provide scientifically verifiable data for the research, giving only media sessions and photo-ops. (wikipedia.org)
  • make
  • The Yanagimachi laboratory and his former associates continue to make advances in cloning. (wikipedia.org)
  • The Eclipse Ti series of inverted microscopes, for example, allows the simultaneous mounting of confocal, TIRF module and multiple stacked epi-fluorescence filter turrets to make this microscope the ideal live cell imaging platform. (wikipedia.org)
  • HeLa
  • He and his colleagues discovered that HeLa cell primase in these cells is in a bound form and they determined the presence of multiple forms of polymerase α. (wikipedia.org)
  • theoretical
  • This classic biological idea has however been perturbed recently by the discovery that the bacterium E. coli may split into distinguishable daughter cells, which opens the theoretical possibility of "age classes" among bacteria. (wikipedia.org)
  • technique
  • In 2013, a calf was produced using the similar cloning technique but the clone survived only for three weeks after suffering from various ailments since its birth. (ibtimes.co.in)
  • Long term timelapse imaging of living cells is becoming an increasingly important technique - for which Nikon has developed the very latest in Cellogy and Cell Care - the BioStation series. (wikipedia.org)
  • Hwang
  • On May 12, 2006, Hwang was charged with embezzlement and bioethics law violations after it emerged much of his stem cell research had been faked. (wikipedia.org)
  • In February 2011, Hwang visited Libya as part of a $133 million project in the North African country to build a stem cell research center and transfer relevant technology. (wikipedia.org)
  • During that period, Hwang claimed to have created a BSE-resistant cow (which has not been verified) and also stated his intention to clone a Siberian tiger. (wikipedia.org)
  • bulls
  • The aim behind the buffalo cloning is to produce clone of offspring tested bulls and buffaloes yielding high lactation, said Srivastava while announcing the achievement. (ibtimes.co.in)
  • produce
  • This allows embryonic stem cells to be employed as useful tools for both research and regenerative medicine, because they can produce limitless numbers of themselves for continued research or clinical use. (wikipedia.org)
  • In contrast, many species can be considered immortal: for example, bacteria fission to produce daughter cells, strawberry plants grow runners to produce clones of themselves, and animals in the genus Hydra have a regenerative ability by which they avoid dying of old age. (wikipedia.org)
  • Korean
  • The Korea Times reported on June 10, 2007, that Seoul National University fired him, and the South Korean government canceled his financial support and barred him from engaging in stem cell research. (wikipedia.org)