• See also Pediatric Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia (AML) . (medscape.com)
  • Myeloid leukemia (myelogenous leukemia) arises from the myeloid line of the white blood cells. (medicinenet.com)
  • Previously, we have developed a p210-breakpoint derived penta-peptide vaccine for controlling minimal residual disease in Chronic Myeloid Leukemia (CML) patients treated with imatinib [ 7 ]. (hindawi.com)
  • Until recently, acute myeloid leukemia (AML) patients used to have limited treatment options, depending solely on cytarabine + anthracycline (7 + 3) intensive chemotherapy and hypomethylating agents. (biomedcentral.com)
  • BCR-ABL1 ) quantitative testing is recommended for patients with either chronic myeloid leukemia (CML), a hematopoietic stem cell disease, or acute lymphoblastic leukemia (ALL), an aggressive type of leukemia of either B- or T-lineage immature lymphoid cells. (arupconsult.com)
  • Learn about remission from acute myeloid leukemia (AML). (medicalnewstoday.com)
  • The U.S. Food and Drug Administration today approved Iclusig (ponatinib) to treat adults with chronic myeloid leukemia and Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL), two rare blood and bone marrow diseases. (news-medical.net)
  • Similar to acute myeloid leukemia, acute lymphoblastic leukemia is caused by a series of acquired genetic aberrations. (msdmanuals.com)
  • This national multi-center study, led by Genomic Medicine Sweden, aims to evaluate whether combined application of WGS and WTS (WGTS) is technically feasible and can be implemented as an efficient diagnostic tool in patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). (lu.se)
  • Results from a large, prospective clinical trial add to mounting evidence that patients with acute lymphoblastic leukemia (ALL) who are adolescent and young adult (defined as ages 16 to 39 years) tend to fare better when treated with high-intensity pediatric protocols than previous patients who were treated with standard adult regimens. (oncologynurseadvisor.com)
  • All participants were treated by adult hematologists-oncologists with a pediatric protocol, including four intensive courses of chemotherapy. (oncologynurseadvisor.com)
  • We showed that adolescents and young adults could tolerate an intensive pediatric regimen. (oncologynurseadvisor.com)
  • The evidence for better results from higher-intensity therapy dates back to 2000, when Stock and pediatric oncologist James Nachman, MD, also from University of Chicago, examined ALL trials conducted over the last 10 years by two cancer cooperative groups: one pediatric and one adult. (oncologynurseadvisor.com)
  • Patients with ALL ages 16 to 21 years who enrolled in pediatric trials had a progression-free survival rate of 68%, whereas patients with ALL ages 16 to 21 years who enrolled in the adult trials had a progression-free survival rate of 34%, approximately the same as patients ages 22 to 39 years. (oncologynurseadvisor.com)
  • Acute lymphoblastic leukemia (ALL) typically responds better when treated with multiagent chemotherapy in the pediatric and young adolescent populations. (nih.gov)
  • In this systematic review, we discuss the efficacy and safety of CD19-specific CAR-T therapy in RR-B-cell ALL in the pediatric and young adult population. (nih.gov)
  • Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children, representing more than a quarter of all pediatric cancers. (medscape.com)
  • Immunoglobulin Heavy Chain High-Throughput Sequencing in Pediatric B-Precursor Acute Lymphoblastic Leukemia: Is the Clonality of the Disease at Diagnosis Related to Its Prognosis? (frontiersin.org)
  • B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common pediatric neoplasm ( 1 , 2 ). (frontiersin.org)
  • Acute lymphoblastic leukemia (ALL) is the most common leukemia in pediatric patients, accounting for up to 80% of cases in children and less frequently in adults. (ejournals.ca)
  • Since 1947, Dana-Farber's sole focus has been to provide expert cancer care and groundbreaking treatments for adult and pediatric patients. (dana-farber.org)
  • Search clinical trials for adult and pediatric cancers and blood disorders offered through Dana-Farber and our clinical partners. (dana-farber.org)
  • The Hematologic Malignancy Center at Dana-Farber/Boston Children's Cancer and Blood Disorders Center is one of the top pediatric leukemia and lymphoma treatment centers in the world. (dana-farber.org)
  • A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia. (cancercentrum.se)
  • Methods and Analysis: The study comprises four phases (i.e., retrospective, prospective, real-time validation, and follow-up) including approximately 700 adult and pediatric Swedish AML and ALL patients. (lu.se)
  • The image below shows pre-B-cell lymphoblastic leukemia/lymphoma (B-ALL). (medscape.com)
  • For the treatment of patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma whose disease has not responded to or has relapsed following treatment with at least 2 chemotherapy regimens. (drugs.com)
  • UAMS Health hematologists work in collaboration with teams of experts from every medical and surgical specialty for the care of patients with blood diseases, including various cancers of the blood and bone marrow, such as leukemia, lymphoma, myeloma, and related amyloid and myeloid diseases. (uamshealth.com)
  • Adult Hodgkin lymphoma treatment depends on the type (classical or nodular lymphocyte predominant) and includes chemotherapy and/or radiation therapy. (uamshealth.com)
  • N. Gilboa, G. M. Lum and R. E. Urizar, "Early Renal Involvement in Acute Lymphoblastic Leukemia and Non-Hodgkin's Lymphoma in Children," Journal of Urology, Vol. 129, No. 2, 1983, pp. 364-367. (scirp.org)
  • Sieniawski M, Bhartia S, Wilkinson J, Proctor S. Incidence and outcome of patients with diffuse large B cell lymphoma with marrow involvement and preliminary experience of an adult acute lymphoblastic leukemia protocol (NEALL VI) in cyclophosphamide, doxorubicin, vincristine, and prednisolone -Rituximab refractory patients . (ncl.ac.uk)
  • Leukemia and Lymphoma 2009, 50 (10), 1726-1730. (ncl.ac.uk)
  • however, because lymphoblastic lymphoma and acute lymphoblastic leukemia (ALL) are known to represent the same disease entity, the World Health Organization (WHO) classification has unified these entities as precursor B-cell and T-cell lymphoblastic leukemia/lymphoma. (medscape.com)
  • 20% lymphoblasts in marrow), a diagnosis of lymphoblastic lymphoma is made. (medscape.com)
  • Lymphoblastic lymphoma is associated with exposure to radiation or pesticides and congenital or acquired immunosuppression and is more common in children and young adults. (medscape.com)
  • Lymphoblastic lymphoma is aggressive and progresses rapidly, presenting as stage IV disease in more than 70% of patients (see Staging). (medscape.com)
  • Many investigators have suggested that both lymphoblastic lymphoma and acute lymphoblastic leukemia (ALL) may be part of one clinical spectrum of a single malignant lymphoproliferative disorder . (medscape.com)
  • Although several subtypes of T-cell lymphoblastic leukemia/lymphoma exist, early T-cell precursor lymphoblastic leukemia (ETP-ALL) is the only subtype recognized as an entity in the revised 2016 WHO tumor classification. (medscape.com)
  • [ 1 ] ETP-ALL frequently has mutations in RUNX1 and/or ETV6 in addition to genes that are more commonly associated with myeloid neoplasms and are otherwise rare in T-cell lymphoblastic leukemia/lymphoma (such as FLT3 , IDH1/2 , TET2 , and DNMT3A mutations). (medscape.com)
  • Non-ETP subtypes of T-cell lymphoblastic leukemia/lymphoma, in contrast, are associated with activating NOTCH1 mutations in over half of all patients and an additional 10% to 15% of cases have FBXW7 mutations, which also result in increased NOTCH signaling. (medscape.com)
  • In the United States, lymphoblastic lymphoma is relatively rare, comprising only 2% of all non-Hodgkin lymphomas (NHLs). (medscape.com)
  • T-lymphoblastic lymphoma (T-LBL) accounts for 25-30% of childhood NHL and is closely related to T-lymphoblastic leukemia (T-ALL). (medscape.com)
  • The estimated overall incidence of acute lymphoblastic leukaemia (ALL) and lymphoblastic lymphoma in Europe is 1.28 per 100 000 individuals annually, with significant age-related variations (0.53 at 45-54 years, ∼1.0 at 55-74 years and 1.45 at 75-99 years). (medscape.com)
  • Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL). (who.int)
  • DNA methylation and copy number variation profiling of T-cell lymphoblastic leukemia and lymphoma. (cancercentrum.se)
  • Acute lymphoblastic leukemia is typically treated initially with chemotherapy aimed at bringing about remission. (wikipedia.org)
  • Treatment usually also includes intrathecal chemotherapy since systemic chemotherapy can have limited penetration into the central nervous system and the central nervous system is a common site for relapse of acute lymphoblastic leukemia. (wikipedia.org)
  • The survival rate of acute lymphoblastic leukemia (ALL) depends on the age of the patient and the response to chemotherapy. (medicinenet.com)
  • Adult acute lymphoblastic leukemia (ALL) treatment options include chemotherapy, radiation therapy, stem cell transplant, and/or targeted therapy. (uamshealth.com)
  • Treatments for leukemia include chemotherapy, radiation therapy, and stem cell transplants. (medicalnewstoday.com)
  • Chemotherapy, radiation therapy, targeted therapy, and stem cell or bone marrow transplant are common treatment options for leukemia. (medicalnewstoday.com)
  • Chemotherapy for leukemia can cause various side effects, depending on the specific drugs, the dosage, and the person. (medicalnewstoday.com)
  • Only 20-30% of adults with ALL are cured with standard chemotherapy regimens. (medscape.com)
  • The use of consolidation chemotherapy in acute lymphoblastic leukemia (ALL) is supported by several studies. (medscape.com)
  • Treatment of ALL needs accurate diagnosis, risk of T-cell acute lymphoblastic leukaemia (T-ALL), no stratification, adapted regimens for chemotherapy, structured studies have been carried out to date ( 7 , 8 ). (who.int)
  • The intergroup trial, presented at the 56th annual meeting of the American Society of Hematology in San Francisco, California, enrolled 296 adolescent and young adult patients with ALL. (oncologynurseadvisor.com)
  • Our results are important because most adolescent and young adult patients with ALL are still treated with lower-intensity adult regimens and are not enrolled on clinical trials. (oncologynurseadvisor.com)
  • Two-year event-free survival for patients with a leukemia-specific molecular genetic profile indicating aggressive disease was 52% compared to 81% for those who lacked the genetic alteration. (oncologynurseadvisor.com)
  • This review discusses the incidence of asparaginase-related adverse events, compares available asparaginase formulations with respect to the emergence of certain toxicities, and considers management strategies for these toxicities in patients with acute lymphoblastic leukemia. (nih.gov)
  • Patients with leukemia may ultimately die due to multiple infections (bacterial, fungal, and viral), severe nutritional deficiencies, and failure of multiple organ systems. (medicinenet.com)
  • The Adult Leukemia Program team at Dana-Farber Brigham Cancer Center has extensive experience caring for patients with ALL and are world leaders in advancing the treatment of leukemia. (dana-farber.org)
  • While ALL is rare in adults, our Adult Leukemia Program cares for a high volume of patients with ALL and has experience caring for newly diagnosed and relapsed patients. (dana-farber.org)
  • This study was designed to describe the survival outcomes of adult patients with ALL seen in a Pakistani population. (aku.edu)
  • Profile of anemia in acute lymphoblastic leukemia patients on maintenance therapy and the effect of micronutrient supplementation. (ejournals.ca)
  • isolates during 2000-2007 in 2 US hospitals, B. breve was isolated from blood culture from 3 adult patients ( 5 ). (cdc.gov)
  • We identified 10,956 patients with de-novo/primary acute lymphoblastic leukemia (1ALL) and 772 with sALL. (elsevierpure.com)
  • Although age is one of the most important prognostic factors in ALL, the outcome was unsatisfactory even in younger adult patients using chemotherapeutic regimen employed in this study. (elsevierpure.com)
  • We performed a nationwide registry-based analysis to describe the clinical outcome of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who underwent an allogeneic hematopoietic stem cell transplantation (HSCT) after a tyrosine kinase inhibitor (TKI)-based treatment A total of 441 patients were included in the study. (uniba.it)
  • The clinical outcome of 21 adults with ALL1(MLL)/AF4 positive acute lymphoblastic leukemia enrolled in the GIMEMA LAL 2000 trial and of 25 patients entered into the previous 0496 study is reported. (unimore.it)
  • For adult patients living with ALL, there is a need for therapeutic options that provide long-term responses," said Bijal Shah, MD, ZUMA-3 investigator and medical oncologist, Moffitt Cancer Center, Tampa, Florida. (gilead.com)
  • The continued durable response and significant improvement in survival indicated by these new data can potentially establish a new standard of care for adult patients living with this aggressive form of leukemia. (gilead.com)
  • ZUMA-3 is an ongoing international multicenter (US, Canada, Europe), single arm, open label, registrational Phase 1/2 study of Tecartus in adult patients (≥18 years old) with ALL whose disease is refractory to or has relapsed following standard systemic therapy or hematopoietic stem cell transplantation. (gilead.com)
  • Acute lymphoblastic leukemia accounts for about 75 to 80 percent of childhood leukemias and 85 percent of newly diagnosed patients go on to become event-free survivors. (dana-farber.org)
  • Acute lymphoblastic leukemia (ALL) is best treated by physicians who have significant experience in the treatment of patients with acute leukemia. (medscape.com)
  • Patients admitted to hospitals that lack appropriate blood product support facilities, leukapheresis capabilities, or physicians and nurses familiar with the treatment of patients with leukemia should be transferred to an appropriate (generally, tertiary care) hospital. (medscape.com)
  • Polygenic risk score-analysis of thromboembolism in patients with acute lymphoblastic leukemia. (cancercentrum.se)
  • Citation: Ghazi B, Elghanmi A, Bouanani N, Maryame A, Nejjari C. Progress towards a cure for acute lymphoblastic leukaemia in Morocco. (who.int)
  • Acute lymphoblastic leukaemia (ALL) is the most unexplained, unless we consider low socioeconomic prevalent paediatric malignancy diagnosed worldwide, status as a key factor. (who.int)
  • TPMT polymorphisms and minimal residual disease after 6-mercaptopurine post-remission consolidation therapy of childhood acute lymphoblastic leukaemia. (cancercentrum.se)
  • The spectrum of acute central nervous system symptoms during the treatment of childhood acute lymphoblastic leukaemia. (cancercentrum.se)
  • Temporal changes of the incidence of childhood B-cell precursor acute lymphoblastic leukaemia in Germany during the COVID-19 pandemic. (who.int)
  • Refractory ALL is a type of leukemia characterized by the failure to achieve complete remission or the recurrence of the disease after initial treatment. (medicalnewstoday.com)
  • Refractory ALL is a more challenging form of leukemia because the cancer cells have become resistant to standard treatments. (medicalnewstoday.com)
  • Results from the analysis showed a median overall survival (OS) of 26 months and demonstrated that responses remained durable in adults with relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL) with a consistent safety profile observed since the two-year analysis. (gilead.com)
  • The European Commission approved Inotuzumab ozogamicin [14] as a monotherapy for the treatment of adults with relapsed or refractory CD22-positive B-cell precursor acute lymphoblastic leukemia (ALL) on June 30, 2017 under the trade name Besponsa® (Pfizer/Wyeth), [15] followed on August 17, 2017 by the FDA. (wikipedia.org)
  • High-throughput sequencing (HTS) of the immunoglobulin heavy chain ( IgH ) locus is a recent very efficient technique to monitor minimal residual disease of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). (frontiersin.org)
  • Multiple-gated acquisition (MUGA) scans or echocardiograms are needed when the diagnosis of ALL is confirmed, because almost all treatment regimens for acute leukemia include anthracyclines (eg, daunorubicin, doxorubicin), which are potentially cardiotoxic. (medscape.com)
  • See the Childhood Acute Lymphoblastic Leukemia: Diagnosis, Management, and Complications slideshow to help recognize and treat this disease and its associated complications. (medscape.com)
  • T-cell acute lymphoblastic leukemia (T-ALL) is an uncommon, aggressive malignancy that rarely presents in the skin and is generally not considered as part of the differential diagnosis by dermatologists and dermatopathologists. (karger.com)
  • Leukemic cell infiltration of the skin (i.e., leukemia cutis) typically occurs after the diagnosis of leukemia and may precede the appearance of leukemic blasts in the peripheral blood [ 2 ]. (karger.com)
  • Diagnosis is typically Acute lymphoblastic leukemia based on blood tests and bone marrow examination. (wikipedia.org)
  • We report a case of an adult woman with a diagnosis of ALL L2. (ejournals.ca)
  • Acute Leukemia: An Illustrated Guide to Diagnosis and Treatment. (ejournals.ca)
  • Chiaretti S, Zini G, Bassan R. Diagnosis and subclassification of acute lymphoblastic leukemia. (ejournals.ca)
  • There was voiced an early diagnosis - acute leukemia. (zp.ua)
  • Acute T cell Lymphoblastic Leukemia should also be kept in differential diagnosis of hematuria, acute renal failure and loss of vision. (scirp.org)
  • We conducted a surveillance epidemiology and end results (SEER)-based analysis to describe the incidence and characteristics of second primary acute lymphoblastic leukemia (sALL) among adults (≥18 years) with a history of primary malignancies (1M). (elsevierpure.com)
  • With these new insights, we can now focus future clinical trial research to build upon the C10403 regimen and evaluate new targeted agents to eradicate minimal residual disease in young adults with ALL and further improve their long-term survival," Stock said. (oncologynurseadvisor.com)
  • We carried out WGS and RNAseq on a cohort of 48 children and young adults with induction failure in T-cell Acute Lymphoblastic Leukemia (T-ALL) to identify genomic drivers of treatment resistance. (ega-archive.org)
  • and a "sporadic" variant, which most frequently occurs in young adults. (cancernetwork.com)
  • Leukemia is a term for cancers of the blood cells. (medlineplus.gov)
  • See Chronic Leukemias: 4 Cancers to Differentiate , a Critical Images slideshow, to help detect chronic leukemias and determine the specific type present. (medscape.com)
  • BACKGROUND: Adult survivors of childhood cancers such as acute lymphoblastic leukemia (ALL) have health problems that persist or develop years after cessation of therapy. (bugsigdb.org)
  • Ph+ acute lymphoblastic leukemia (Ph+ ALL) is a high-risk acute leukemia with poor prognosis, in which the specific t(9;22)(q34;q11) translocation results in a chimeric bcr-abl (e1a2 breakpoint) and in a 190 KD protein (p190) with constitutive tyrosine kinase activity. (hindawi.com)
  • abstract = "Background: Childhood acute lymphoblastic leukemia (ALL) is associated with cognitive impairment in adulthood. (lu.se)
  • Relapse risk following truncation of PEG-asparaginase in childhood acute lymphoblastic leukemia. (cancercentrum.se)
  • ÓG, Vaitkeviciene G, Lepik K, Forslund A, Heyman M, Harila-Saari A. Impact of body mass index on relapse in children with acute lymphoblastic leukemia treated according to Nordic treatment protocols. (cancercentrum.se)
  • As an acute leukemia, ALL progresses rapidly and is typically fatal within weeks or months if left untreated. (wikipedia.org)
  • Central nervous system (CNS) symptoms such as cranial neuropathies due to meningeal infiltration are identified in less than 10% of adults and less than 5% of children, particularly mature B-cell ALL (Burkitt leukemia) at presentation. (wikipedia.org)
  • There is an abnormally high production of white bloodless (cells that fight infection and provide immunity), which are unable to mature properly leading to the symptoms in leukemia. (medicinenet.com)
  • Загальні відомості про лейкоз Leukemia is a malignant condition involving the excess production of immature or abnormal leukocytes, which eventually suppresses the production of normal blood cells and results in symptoms. (msdmanuals.com)
  • This is in contrast to childhood ALL in which the complete remission rates and overall survival are about 80%.In adults poor outcome is associated with older age, high white cell count and Philadelphia chromosome positivity.3-7 There are a number of studies about the outcomes of adults diagnosed to have ALL in the literature. (aku.edu)
  • The Japan Adult Leukemia Study Group conducted the ALL-87 study to determine whether response-oriented induction therapy and intensive consolidation and maintenance/intensification therapies could increase complete remission (CR) rate and survival in adult acute lymphoblastic leukemia (ALL). (elsevierpure.com)
  • Fiere et al compared consolidation therapy with daunorubicin and cytosine arabinoside (Ara-C) versus no consolidation therapy in adults with ALL, demonstrating a 38% 3-year, leukemia-free survival rate for subjects receiving consolidation and maintenance therapy compared with 0% for those receiving maintenance therapy without consolidation. (medscape.com)
  • The last decade has witnessed great advances in our understanding of the genetic and biological basis of childhood acute lymphoblastic leukemia (ALL), the development of experimental models to probe mechanisms and evaluate new therapies, and the development of more efficacious treatment stratification. (haematologica.org)
  • Several lines of evidence indicate that there is a genetic predisposition to acute lymphoblastic leukemia (ALL), at least in a subset of cases. (haematologica.org)
  • Asparaginase therapy is an essential component of the treatment protocol for acute lymphoblastic leukemia. (nih.gov)
  • Specialized program with expertise in cutting-edge leukemia diagnostics, treatment planning, management of therapy and complications. (dana-farber.org)
  • Response-oriented induction therapy produced a high CR rate, but fairly intensive consolidation and maintenance/intensification chemotherapies resulted in only a marginal effect on DFS in adult ALL. (elsevierpure.com)
  • A study by the Cancer and Leukemia Group B (CALGB) did not show a benefit to consolidation therapy. (medscape.com)
  • Subjects with Philadelphia Chromosome positive acute lymphoblastic leukemia (Ph+ALL) subjects are eligible if they progressed, had stable disease or relapsed after two lines of therapy, including tyrosine kinase inhibitors (TKIs). (who.int)
  • Acute lymphoblastic leukemia and down syndrome: 6-mercaptopurine and methotrexate metabolites during maintenance therapy. (cancercentrum.se)
  • The American Cancer Society estimates that in the United States in 2022 there will be over 6600 new cases of acute lymphoblastic leukemia (ALL) and almost 1600 deaths will have occurred. (msdmanuals.com)
  • Philadelphia positive acute lymphoblastic leukemia (Ph+ ALL) is a high-risk, aggressive form of acute leukemia, affecting primarily adults and the elderly. (hindawi.com)
  • Acute lymphoblastic leukemia (ALL) in adults is a rare malignancy. (aku.edu)
  • Morocco because of the absence of electronic medical the Group for Research on Adult Acute Lymphoblastic records, and inaccurate and exhaustive collection and Leukemia protocols ( 2 , 3 ). (who.int)
  • Conclusion: Adult childhood ALL survivors demonstrated impaired behavioral performance but no altered fMRI activity when performing cognitive interference processing when compared with controls. (lu.se)
  • ALL is the most common type of cancer and leukemia in children in the United States. (medscape.com)
  • Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. (wikipedia.org)
  • Acute lymphoblastic leukemia is notable for being the first disseminated cancer to be cured. (wikipedia.org)
  • Children and teens with acute lymphoblastic leukemia are treated by our experts at Dana-Farber/Boston Children's Cancer and Blood Disorders Center through the Childhood Leukemia Program . (dana-farber.org)
  • Hospitalizations in long-term survivors of childhood AML treated with allogeneic HCT-An Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study. (cancercentrum.se)
  • Study protocol for the Fex-Can Childhood project: An observational study and a randomized controlled trial focusing on sexual dysfunction and fertility-related distress in young adult survivors of childhood cancer. (cancercentrum.se)
  • Chapter 35: Acute leukemias in Rodak's Hematology Clinical Principles and Applications, Keohane EM. (ejournals.ca)
  • It's FDA-approved to treat a certain type of acute lymphoblastic leukemia (ALL) in adults and in children. (medicalnewstoday.com)
  • It is mostly adults (rarely children) who are affected by CLL. (differencebetween.net)
  • While CLL is more common among adults, ALL is more common among children. (differencebetween.net)
  • While 80% of ALL occurs in children, it represents a devastating disease in adults. (gilead.com)
  • The vaccine has been shown to be safe and effective in healthy and immunocompromised children, and healthy adults. (cdc.gov)
  • This report provides technical guidance about common vaccination concerns for clinicians and other health-care providers who administer vaccines to infants, children, adolescents, and adults. (cdc.gov)
  • Any person or institution that provides vaccination services should adopt these standards to improve vaccination delivery and protect infants, children, adolescents, and adults from vaccine-preventable diseases. (cdc.gov)
  • CONCLUSIONS: Young adult survivors of childhood ALL, especially those treated with CRT, are at risk for obesity and dyslipidemia, insulin resistance, hypertension, and cardiovascular disease. (duke.edu)
  • Adult ALL is a heterogeneous disease significantly different from childhood ALL. (aku.edu)
  • Leukemia remission is when there is no evidence of the disease during treatment. (medicalnewstoday.com)
  • In other words, it is a period when leukemia is in a state of minimal or undetectable disease activity. (medicalnewstoday.com)
  • PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment. (bvsalud.org)
  • The therapeutic response and clinical outcome of adults with ALL1(MLL)/AF4 fusion positive acute lymphoblastic leukemia according to the GIMEMA experience. (unimore.it)
  • U. , D. Santhosh, S. Kumar, R. Singh and J. Prakash, "Adult Acute T Cell Leukemia Presenting as Acute Renal Failure, Parotid Swelling and Loss of Vision," International Journal of Clinical Medicine , Vol. 5 No. 1, 2014, pp. 32-35. (scirp.org)
  • H. H. Hsu, Y. L. Chan and C. C. Huang, "Acute Spontaneous Tumor Lysis Presenting with Hyperuricemic Acute Renal Failure: Clinical Features and Therapeutic Approach," Journal of Nephrology, Vol. 17, No. 1, 2004, pp. 50-56. (scirp.org)
  • For fit and motivated older adults with Ph-positive ALL, I will typically recommend they undergo a transplant in first remission. (onclive.com)
  • Acute lymphoblastic leukemia emerges when a single lymphoblast gains many mutations to genes that affect blood cell development and proliferation. (wikipedia.org)
  • K. P. Harris, J. M. Hattersley, J. Feehally and J. Walls, "Acute Renal Failure Associated with Haematological Malignancies: A Review of 10 Years Experience," European Journal of Haematology, Vol. 47, No. 2, 1991, pp. 119-122. (scirp.org)
  • You and your family have access to our full range of support services such as nutrition , social work , geriatrics , the Zakim Center for Integrative Therapies and Healthy Living , the Young Adult Program , and survivorship . (dana-farber.org)
  • Therapies for adults with newly diagnosed Ph+ ALL are limited and associated with poor outcomes. (confex.com)
  • O. M. Suriya and A. Aleem, "Frank Hematuria as the Presentation Feature of Acute Leukemia," Saudi Journal of Kidney Diseases and Transplantation, Vol. 21, No. 5, 2010, pp. 940-942. (scirp.org)
  • We describe a case of B. breve sepsis in a child with Philadelphia chromosome-positive acute B-cell lymphoblastic leukemia. (cdc.gov)
  • Lymphoblastic leukemias/lymphomas are neoplasms of precursor T cells and B cells or lymphoblasts. (medscape.com)
  • PURPOSE: To assess cardiovascular risk factors (CVRF) in young adult survivors of childhood acute lymphoblastic leukemia (ALL). (duke.edu)
  • RESULTS: We compared the anal microbiota composition of adult survivors of childhood ALL (N = 73) with healthy control subjects (N = 61). (bugsigdb.org)
  • 2013). Evaluation of memory impairment in aging adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiotherapy. (bvsalud.org)