• Additionally, CGRP might be important in processes such as control of fetoplacental vascular tone, regulation of calcium metabolism and insulin secretion, acetylcholine receptor synthesis, peripheral nerve regeneration, and neurogenic inflammation. (bachem.com)
  • these, in turn, feed back to regulate aldosterone secretion by the zona glomerulosa of the adrenal cortex. (medscape.com)
  • The mechanisms regulating aldosterone secretion are complex, involving the zona glomerulosa of the adrenal glands, the juxtaglomerular apparatus in the kidneys, the cardiovascular system, the autonomic nervous system, the lungs, and the liver (see the image below). (medscape.com)
  • ACTH stimulates aldosterone secretion in an acute and transient fashion but does not appear to play a significant role in the long-term regulation of mineralocorticoid secretion. (medscape.com)
  • Although ANP levels are clearly increased in hyperaldosteronism, neither ANP nor dopamine has been implicated as a primary cause of clinically disordered aldosterone secretion. (medscape.com)
  • Metoclopramide has been shown to increase aldosterone secretion, suggesting that dopamine may tonically inhibit aldosterone release. (medscape.com)
  • The physiologic roles of adrenomedullin and vasoactive intestinal peptide (VIP) on aldosterone secretion remain to be clarified, although both of these neuropeptides are produced in rat zona glomerulosa. (medscape.com)
  • Angiotensin II is both a stimulator of aldosterone secretion and a potent vasopressor. (medscape.com)
  • Angiotensin II is metabolized to angiotensin III, a heptapeptide that is also a stimulator of aldosterone secretion. (medscape.com)
  • This review focuses on the knowledge related to the possible modulation of cortisol and aldosterone secretion under non-stress and stress conditions by antipsychotic drugs, which are being used in the treatment of several psychotic and affective disorders. (bvsalud.org)
  • Among the neuropeptides two groups of peptides can be discriminated: pro-inflammatory peptides like tumour necrosis factor alpha (TNFα), the interleukins IL-1β, IL-2, IL-6 and IL-12 and -on the other hand- anti-inflammatory peptides such as urocortin, adrenomedullin, vasoactive intestinal peptide VIP, and GHrelin. (biomedres.us)
  • The principal regulators of aldosterone synthesis and secretion are the renin-angiotensin system and the potassium ion concentration. (medscape.com)
  • The synthesis of prorenin, its conversion to renin, and its systemic secretion are stimulated by blood volume contraction detected by stretch receptors, beta-adrenergic stimulation of the sympathetic nervous system, and prostaglandins I 2 and E 2 . (medscape.com)
  • The synthesis and secretion of prostaglandins I 2 and E 2 and the normal function of the stretch receptors are dependent on the intracellular ionized calcium concentration. (medscape.com)
  • Minor regulators include adrenocorticotropic hormone (ACTH) from the pituitary, atrial natriuretic peptide from the heart, and local adrenal secretion of dopamine. (medscape.com)
  • The CALC1 gene belongs to a superfamily of related protein hormone precursors including islet amyloid precursor protein, calcitonin gene-related peptide, and the precursor of adrenomedullin. (wikipedia.org)
  • Secretion of calcitonin is stimulated by: an increase in serum [Ca2+] gastrin and pentagastrin. (wikipedia.org)
  • α-CGRP and β-CGRP, also known as CGRP I and II, respectively, belong to the calcitonin family of peptides comprising such members as calcitonin, amylin, calcitonin receptor-stimulating peptide, adrenomedullin 1, and intermedin. (bachem.com)
  • During middle to past due gestation, myometrial quiescence is certainly maintained by many contractile inhibitors, such as for example relaxin, adrenomedullin, nitric oxide, progesterone and prostacyclin [1,2]. (researchensemble.com)
  • Such agents include natriuretic peptides most notably B-type natriuretic peptide (nesiritide), neutral endopeptidase (NEP) inhibi- tors (thiorphan, phosphoramidon), mixed NEP and ACE inhibitors (omapatrilat), guanylin and uroguanylin, kinins, prostaglandins of the E series, adrenomedullin, relaxin. (best10forexbrokers.com)
  • Görgens SW, Raschke S, Holven KB, Jensen J, Eckardt K, Eckel J. Regulation of follistatin-like protein 1 expression and secretion in primary human skeletal muscle cells. (ac.ir)
  • From the conditioned reflex activity in gastric acid secretion discovered by Pavlov to the recognition of the role of CNS in stress-induced gastric ulcer and exacerbation of intestinal inflammation, all these facts confirm the significance of brain-gut axis. (cyberleninka.ru)
  • Furthermore, it influences feeding and digestion since it has been shown to decrease food intake, gastric secretion, and intestinal motility. (bachem.com)
  • Clinical studies performed in healthy subjects, patients with psychosis, and patients with bipolar disorder suggest that single and repeated antipsychotic treatments either reduce cortisol concentrations or do not affect its secretion. (bvsalud.org)
  • AIMS: Adrenomedullin (ADM) is a vasodilatory peptide. (phoenixpeptide.com)
  • Adrenomedullin (AM) is a 52-amino acid peptide with a pluripotentialactivity. (phoenixpeptide.com)
  • Adrenomedullin (AM), an ubiquitous regulatory peptide with different actions, is known to be elevated in different clinical situations, including diabetes mellitus (DM), but its potential role in the pathogenesis of diabetic vascular complications is not clear. (phoenixpeptide.com)
  • Indeed, MSCs ex vivo pre-conditioning by hypoxia, inflammatory stimulus, or other factors/conditions may stimulate their survival, proliferation, migration, exosome secretion, and pro-angiogenic and anti-inflammatory characteristics in vivo. (biomedcentral.com)
  • Mid-regional pro-adrenomedullin as a novel predictor of mortality in patients with chronic heart failure. (phoenixpeptide.com)
  • CONCLUSION: Mid-regional pro-adrenomedullin is an independent predictor of mortality in CHF patients, which adds prognostic information to NT-proBNP. (phoenixpeptide.com)
  • Levels of plasma total adrenomedullin are related with two acute phase inflammatory reactants (fibrinogen and sialic acid) but not with markers of endothelial dysfunction in Type 1 diabetes Adrenomedullin and vascular risk factors in Type 1 DM. (phoenixpeptide.com)
  • Inflammation is the first innate immune response to infection or irritation resulting from leukocyte ( neutrophils , mast cells , etc.) accumulation and their secretion of inflammatory, biogenic chemicals such as histamine , prostaglandin , and pro-inflammatory cytokines . (wikidoc.org)
  • In NYHA II- and III-patients urocortin, adrenomedullin and VIP were elevated, while Ghrelin, TNFα, IL-12 and IL-2 were unchanged. (biomedres.us)