Loading...
  • glands
  • Primary pigmented nodular adrenocortical disease (PPNAD) is a pituitary-independent, primary adrenal form of hypercortisolism characterized by (a) resistance to suppression by dexamethasone and abolition of the normal diurnal rhythm of cortisol secretion, and (b) distinctive, bilateral, histopathologic changes of the adrenal glands, such as the formation of variably sized, pigmented nodular adenomas, loss of normal zonation and atrophy of the extranodular cortex. (clinicaltrials.gov)
  • Symptoms primarily result from lack of mineralocorticoids and/or glucocorticoids and this condition may be triggered by lesions of the adrenal glands themselves or by pathologies of superior regulatory centers. (symptoma.com)
  • Adopting the adrenal fatigue diet, adrenal fatigue natural supplements, and adrenal fatigue lifestyle including positive thoughts can help heal your adrenal glands. (symptoma.com)
  • Phase
  • To this end the trial compares the two most promising drug combinations investigated in phase II trials, considered by the 'International Consensus Conference on Adrenal Cancer' (Ann Arbor/USA, 2003) as valuable first line treatments for advanced ACC. (clinicaltrials.gov)
  • insufficiency
  • Symptoms Adrenal insufficiency can present either as an acute crisis with vascular collapse or as a chronic insufficiency, which has much more obscure symptomology. (symptoma.com)
  • patients
  • Patients may present with rather non-specific symptoms or be admitted for emergency care because of an adrenal crisis . (symptoma.com)
  • Condition
  • The adrenal or Addisonian crisis is a life-threatening condition most commonly observed in individuals affected by primary AI. (symptoma.com)
  • malignancy
  • Objective: Here we developed a novel steroid metabolomic approach, mass spectrometry-based steroid profiling followed by machine learning analysis, and examined its diagnostic value for the detection of adrenal malignancy. (uni-wuerzburg.de)
  • treatment
  • Andrew Arnold The past several years have been a time of intense excitement and have brought major advances in the understanding and treatment of endocrine neoplasms. (springer.com)