• Functional Polymorphism in the ADRB3 Gene, Encoding the Beta-3 Adrenergic Receptor, and Response to Intra-Detrusor Injection of Botulinum Toxin-A in Women with Overactive Bladder. (urotoday.com)
  • There are reports suggesting an association between the rs4994 polymorphism in the ADRB3 gene encoding the beta-3 adrenergic receptor and OAB risk in females. (urotoday.com)
  • The beta-3 adrenergic receptor (β3-adrenoceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it. (wikipedia.org)
  • Beta-3-adrenergic receptor (ADRB3) as well as chondromodulin-1 (CHM1) are over-expressed in Ewing Sarcoma (ES) but not on T cells. (oncotarget.com)
  • It was determined that the alleged capacity of AOD 9604 to raise the synthesis of beta-3 adrenergic receptors (also known as ADRB3 in obese mice) may have been responsible for this finding. (asianage.com)
  • In order to investigate whether the variances in the candidate genes (Insulin receptor substrate IRS-1, beta3-adrenergic receptor ADRB3, 3 beta-hydro-xysteroid dehydrogenase HSD3B2, glucocorticoid receptor GRL and 21-hydroxylase CYP21) which affect the metabolism of adrenal steroids hormone and body composition, are associated with precocious puberty in Chinese girls. (nel.edu)
  • The fat-burning action of Fragment 176-191 peptide is brought about by increasing the production of beta-3 adrenergic receptors (3-AR or ADRB3). (phd10.com)
  • The aim of our study was to analyze the possible association between the ADRB3:rs4994 polymorphism and the patient-perceived response to a single intra-detrusor injection of botulinum toxin-A in Polish women with overactive bladder. (urotoday.com)
  • Our results do not support the hypothesis that ADRB3:rs4994 polymorphism is associated with the response to the intra-detrusor injection of botulinum toxin-A in Polish females with overactive bladder. (urotoday.com)
  • Objective: Determine the distribution of allelic and genotypic frequencies and the relation of the polymorphism rs4998 of the ADRB3 gene with the Body Mass Index in a population of teachers and administrators of an university institution in Colombia. (unab.edu.co)
  • Results: No significant differences between the players who entered the national team and the ones who did not were found in ACTN3 R577X ( p = 0.437) and ADRB3 ( p = 0.202) polymorphism distribution, while the differences existed in ACE ( p = 0.044). (balticsportscience.com)
  • Because thermogenesis in skeletal muscle and fat burning in adipose tissue are two effects of ADRB3 that have been well studied, there is a significant amount of scientific interest in determining whether or not Fragment 176-191 may give comparable properties in research models. (asianage.com)
  • The response to botulinum toxin-A was evaluated at three months after injection, as absolute or relative reductions in OAB symptoms or in scores from questionnaires ICIQ-OAB (parts A and B) and ICIQ-LUTS-QoL (parts A and B). ADRB3:rs4994 variants were identified by the sequencing of genomic DNA extracted from buccal swabs. (urotoday.com)
  • Introduction: This study investigated the differences in ACTN3, ACE and ADRB3 variants in top-level soccer players who entered the Croatian National Team and the ones who did not but played for two best Croatian teams. (balticsportscience.com)
  • As suggested by these results, a separate regulatory route for lipolysis may take precedence over the activity of ADRB3 when the animal's body weight sits closer to its normal range. (asianage.com)
  • A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ADRB3 (NP_000016.1). (prosci-inc.com)
  • The beta-3 adrenergic receptor (β3-adrenoceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it. (wikipedia.org)
  • Beta-3-adrenergic receptor (ADRB3) as well as chondromodulin-1 (CHM1) are over-expressed in Ewing Sarcoma (ES) but not on T cells. (oncotarget.com)
  • The β-2 and β-3 adrenergic receptors (ADRB2 and ADRB3) are thought to play a role in energy expenditure and lipolysis. (upm.es)
  • It is thought that this action is mediated through an increase in production of beta-3 adrenergic receptors (β3-AR or ADRB3). (humapeptide.com)
  • However, the effects of the ADRB2 glutamine (Gln) 27 glutamic acid (glutamate) (Glu) and ADRB3 tryptophan (Trp) 64 arginine (Arg) polymorphisms on weight loss remain controversial. (upm.es)
  • Variation in the ADRB3 gene (ADRB3) has been associated with obesity and the earlier onset of non-insulin-dependent diabetes mellitus in some ethnic groups, as well as some production traits of sheep, but to date variation of bovine ADRB3 has not been reported. (nih.gov)
  • Extensive diversity of the ADRB3 gene in Chinese sheep identified by PCR-SSCP. (nih.gov)
  • Extended haplotype analysis of ovine ADRB3 using polymerase chain reaction single strand conformational polymorphism on two regions of the gene. (nih.gov)
  • Current evidence supports the association between the ADRB3 gene and insulin resistance in schizophrenia. (psychiatrist.com)
  • Molecular variants of genes that influence obesity and insulin (androgen receptor gene (AR), vitamin D receptor gene(VDR), insulin receptor (ADRB3)) will be examined both independently and in conjunction with metabolic factors to determine differences in genetic susceptibility in the population. (grantome.com)
  • The β3-adrenergic receptor (ADRB3) is expressed predominantly in human visceral fat and is the principal mediator of catecholamine-stimulated thermogenesis and lipolysis. (psychiatrist.com)
  • These findings indicate that there are secondary regulatory pathways for lipolysis that override ADRB3 function when body weight is at or near ideal, opening up areas for additional research into energy homeostatsis. (humapeptide.com)
  • In this study, variation in the promoter region of bovine ADRB3 was investigated in 737 cattle by polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) analysis. (nih.gov)
  • There seems to be an individual effect of the ADRB3 polymorphism on fat mass (p = 0.004) and fat percentage (p = 0.036), in addition to an interaction with exercise for fat mass (p = 0.038). (upm.es)
  • The β(3)-adrenergic receptor (ADRB3) is predominantly expressed in white and brown adipose tissue and mediates the lipolytic and thermogenic effects of high catecholamine concentrations. (nih.gov)
  • Therefore, ADRB3 dysfunction leads to visceral obesity, correlated with insulin resistance through its effect on energy expenditure of fat tissue. (psychiatrist.com)
  • No article was found for Arteriosclerosis and meta-analysis and ADRB3[original query] . (cdc.gov)
  • Mice that have been genetically modified to produce no ADRB3 do not respond to the lipolytic effects of hGH or fragment 177-191. (humapeptide.com)
  • The variation identified here might have an impact on both the function and level of expression of bovine ADRB3. (nih.gov)