Administration of dexamethasone. Medical search. Frequent questions

In the double-blind, placebo-controlled TOURMALINE-MM2 trial, transplant-ineligible NDMM patients were randomized to ixazomib 4 mg (n = 351) or placebo (n = 354) plus Rd. After 18 cycles, dexamethasone was discontinued and treatment was continued using reduced-dose ixazomib (3 mg) and lenalidomide (10 mg) until progression/toxicity. (nih.gov)

Continuous lenalidomide-dexamethasone (Rd)-based regimens are among the standards of care in transplant-ineligible newly diagnosed multiple myeloma (NDMM) patients. (nih.gov)
On July 24, 2015, carfilzomib (Kyprolis) was approved for use in combination with lenalidomide (Revlimid) and dexamethasone in the treatment of patients with relapsed multiple myeloma who have received one to three prior lines of therapy. (ascopost.com)
The new approval was based on improved progression-free survival in a phase III open-label trial in which 792 patients with relapsed or refractory multiple myeloma after one to three lines of prior therapy were randomly assigned to receive lenalidomide plus low-dose dexamethasone with (n = 396) or without carfilzomib (n = 396) for 18 cycles. (ascopost.com)
3 Lenalidomide and dexamethasone were continued thereafter until disease progression. (ascopost.com)
Oral lenalidomide is given at 25 mg on days 1 to 21, and oral or intravenous dexamethasone at 40 mg on days 1, 8, 15, and 22 of each cycle. (ascopost.com)
Patients taking three drugs -- carfilzomib, lenalidomide and dexamethasone -- stayed free of disease progression for 26 months on average," he says. (sciencedaily.com)
Researchers found that adding carfilzomib to standard treatment (lenalidomide and dexamethasone) resulted in 8.7 months of longer remission, almost 50 percent longer than the standard two-drug combination (26.3 months versus 17.6 months). (sciencedaily.com)
Kyprolis, Lenalidomide, and Dexamethasone (KRd) or Kyprolis Monotherapy: 20/27 mg/m 2 twice weekly. (aetna.com)

Dexamethasone is given in usual doses of 0.5 to 10 mg daily, depending on the disease being treated. (medicines.org.uk)
CONCLUSIONS: Pharmacological doses of dexamethasone and isoflupredone have suppressive actions on the circulating levels of thyroid hormones in Holstein calves possibly via inhibition of TSH production at hypothalamic-pituitary-thyroid level. (ac.ir)
Patients should be premedicated with dexamethasone at the recommended dose prior to all cycle 1 doses and if infusion reactions occur or recur. (ascopost.com)
This study compared outcomes in 18 patients given placebo with outcomes in 20 patients given dexamethasone 3 mg/kg IV over 30 minutes followed by dexamethasone 1 mg/kg every 6 hours for 8 doses. (medscape.com)
A 1991 trial compared patients treated with 12 doses of dexamethasone 400 mg or 100 mg to a retrospective cohort in whom steroids were not administered. (medscape.com)
The test is given at low and high doses of Dexamethasone and the levels of cortisol are measured to obtain the results. (wikidoc.org)
they are seen only after administration of large therapeutic doses of the drug. (drugs.com)
The systemic availability, metabolism and elimination of prednisolone after administration of single weight-based doses (0.8 mg/ kg) of intravenous (IV) prednisolone and oral prednisone were reported in a small study of 19 young (23 to 34 years) and 12 elderly (65 to 89 years) subjects. (drugs.com)
However, the dose of 6 mg of dexamethasone is currently being reappraised and may miss important therapeutic potential or may prevent potential deleterious effects of higher doses of corticosteroids. (biomedcentral.com)
We aim to compare two different doses of dexamethasone in patients with moderate to severe ARDS undergoing mechanical ventilation regarding efficacy and safety. (biomedcentral.com)
Premedicate Kyprolis infusions with dexamethasone prior to all Cycle 1 doses and if infusion reaction symptoms develop or reappear. (aetna.com)
1 Compared to some of the older steroids, dexamethasone is significantly more effective as an anti-inflammatory drug and requires lower doses for treatment. (imprimedicine.com)
If your pet is on high doses of dexamethasone (20 or 40 mg per day for 4 days out of the month), and you forget to give your dog a dose, contact your veterinarian. (imprimedicine.com)

Topical corticosteroid eye drops, such as 0.1% dexamethasone and 1% prednisolone acetate, are commonly applied for two to four weeks until the intraocular inflammation subsided clinically. (springer.com)
Dexamethasone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands. (medlineplus.gov)
Dexamethasone phosphate (DP) is a synthetic corticosteroid that is commonly administered to premature infants for the prevention or treatment of bronchopulmonary dysplasia (BPD). (bmj.com)
Dexamethasone is a powerful, synthetic corticosteroid which has anti-inflammatory and immunosuppressive properties. (imprimedicine.com)
patients who are receiving dexamethasone or another corticosteroid for other indications should continue therapy for their underlying conditions as directed by their healthcare providers. (cdc.gov)

We conducted a single-blind, placebo-controlled study in 20 men randomized to receive dexamethasone (8 mg/d) or placebo for 1 wk. (qxmd.com)
We evaluate whether a single dose of oral dexamethasone plus 4 days of placebo is not inferior to 5 days of oral prednisone in treatment of adults with mild to moderate asthma exacerbations to prevent relapse defined as an unscheduled return visit for additional treatment for persistent or worsening asthma within 14 days. (nih.gov)
Adult emergency department patients (aged 18 to 55 years) were randomized to receive either a single dose of 12 mg of oral dexamethasone with 4 days of placebo or a 5-day course of oral prednisone 60 mg a day. (nih.gov)
The fatality rate in the dexamethasone arm was 10% versus 55.6% in the placebo arm ( P =.003). (medscape.com)
The second ATorvastatin On Chronic subdural Hematoma (ATOCH-II) study is a multi-center, randomized, placebo-controlled, double blind trial which aims to enroll 240 adult patients with a conservative therapeutic indication for CSDH, randomly allocated to standard treatment with atorvastatin 20 mg combined with low-dose dexamethasone (or matching placebos) daily for 28 days, and with 152 days of follow-up. (researchsquare.com)
The patients were carefully allocated and divided into 2 groups: Group 1 (dexamethasone and placebo) and group 2 (dexamethasone and nimesulide). (bvsalud.org)

In addition to dexamethasone, the president is being treated with remdesivir, an experimental anti-viral drug made by Gilead Sciences . (npr.org)
Racial and ethnic differences were smaller for inpatient administration of remdesivir and dexamethasone. (cdc.gov)
Dexamethasone, a commonly used steroid, and remdesivir, an antiviral drug that received EUA from FDA in May 2020, are used in inpatient settings and help prevent COVID-19 progression § ( 2 ). (cdc.gov)
Relative disparities in mAb** treatment among all patients †† (805,276) with a positive SARS-CoV-2 test result and in dexamethasone and remdesivir treatment among inpatients §§ (120,204) with a positive SARS-CoV-2 test result were calculated. (cdc.gov)
Among inpatients, disparities were different and of lesser magnitude: Hispanic inpatients received dexamethasone 6% less often than did non-Hispanic inpatients, and Black inpatients received remdesivir 9% more often than did White inpatients. (cdc.gov)
Health officials do not approve therapeutics other than remdesivir and dexamethasone. (bcg.com)
These include remdesivir and dexamethasone for children in certain age groups. (news-medical.net)
Remdesivir is the only antiviral drug currently approved by the U.S. Food and Drug Administration (FDA) for treatment of people ages 12 and older hospitalized with COVID-19 who have risk factors for severe disease and the need for supplemental oxygen, and it is most effective when given as soon as possible after symptoms began. (news-medical.net)
d Administration of remdesivir requires 3 consecutive days of IV infusion. (cdc.gov)

Dexamethasone has anti-inflammatory and immunosuppressant effects. (wikipedia.org)
Dexamethasone Injection is indicated for the treatment of primary bovine ketosis and as an anti-inflammatory agent in cattle and horses. (valleyvet.com)
As supportive therapy, dexamethasone may be used in the management of various rheumatic, allergic, dermatologic, and other diseases known to be responsive to anti-inflammatory corticosteroids. (valleyvet.com)
However, while the anti-inflammatory effects of dexamethasone treatment were due to the reduced activation of NF- κ B and AP-1, the ellagic acid treatment led to reduced BALF levels of IL-6 and increased levels of IL-10. (hindawi.com)
As an anti-inflammatory medication, dexamethasone is particularly helpful in reducing swelling and redness from allergic reactions as well as pain from conditions such as arthritis. (imprimedicine.com)

[2] A normal result is decrease in cortisol levels upon administration of low-dose dexamethasone. (wikidoc.org)
Results indicative of Cushing's disease involve no change in cortisol on low-dose dexamethasone, but inhibition of cortisol on high-dose dexamethasone. (wikidoc.org)
If the cortisol levels are unchanged by low and high-dose dexamethasone then a cortisol secreting adrenocortical tumor is suspected or an ectopic ACTH syndrome. (wikidoc.org)
Dexamethasone suppressed the plasma and urine levels of cortisol and irEDLS. (lu.se)
Other protocols suggest starting dexamethasone 0.5 mg orally every 6 hours starting at noon for 48 hours and checking cortisol level 2 hours (8 am) after the last dose. (medscape.com)

Data from CDC (1, 2) (highlighted in a February 13, 2021 CDC/ external icon Infectious Diseases Society of America COVID-19 Clinical Call) and the Food and Drug Administration (3) suggest that there has been increasing use of systemic corticosteroids and antibiotics to treat outpatients with COVID-19. (cdc.gov)

Carfilzomib is a proteasome inhibitor approved for use in 2012 by the U.S. Food and Drug Administration (FDA) for patients with advanced, end-stage multiple myeloma. (sciencedaily.com)
Dexamethasone is used to treat a variety of cancers such as leukemia, lymphoma, and multiple myeloma, and prevents swelling associated with tumors of the spine and brain. (imprimedicine.com)

In conclusion, we found no statistically significant difference between subtenon 20-mg triamcinolone injection and 0.1% dexamethasone eye drop to control inflammation postoperatively. (springer.com)
Dexamethasone is indicated for the treatment of acute musculoskeletal inflammation in horses. (valleyvet.com)
Here, we used the nonlethal acid-initiated experimental model of ALI to determine whether preventive or therapeutic administration of ellagic acid could interfere with the development and establishment of ALI-associated inflammation. (hindawi.com)
This multi-centre clinical trial aims to provide high-quality evidence on the efficacy and safety of the combined treatment of atorvastatin and low-dose dexamethasone to reduce inflammation and enhance angiogenesis in CSDH. (researchsquare.com)

Oral dexamethasone demonstrates bioavailability similar to that of oral prednisone but has a longer half-life. (nih.gov)
A single dose of oral dexamethasone did not demonstrate noninferiority to prednisone for 5 days by a very small margin for treatment of adults with mild to moderate asthma exacerbations. (nih.gov)
PREZCOBIX tablets are for oral administration. (rxlist.com)
Prednisolone is rapidly and well absorbed from the gastrointestinal tract following oral administration. (drugs.com)
Overnight suppression test: Administer 1 mg oral dexamethasone between 11 pm and midnight. (medscape.com)
Standard 2-day dexamethasone suppression test: Administer 0.5 mg oral dexamethasone every 6 hours for 48 hours (9 am, 3 pm, 9 pm, and 3 am). (medscape.com)

Dexamethasone 0.1 mg kg -1 , mannitol infusion 0.5 mg kg -1 and furosemid 0.1 mg kg -1 IV were administered to the patient to decrease brain edema and ICP. (ispub.com)
Dexamethasone sodium phosphate solution for injection 4 mg/mL or 10 mg/mL may be added to 5% Dextrose injection or 0.9% Sodium Chloride injection, USP and given by IV infusion. (pdr.net)

Dexamethasone is indicated in the treatment of coronavirus disease 2019 (COVID-19) in adult and adolescent patients (aged 12 years and older with body weight at least 40 kg) who require supplemental oxygen therapy. (medicines.org.uk)
All patients should receive hydration prior to administration and, as needed, following administration. (ascopost.com)
Seventy patients received subtenon 20-mg triamcinolone injection (TA group), whereas the other 70 patients received 0.1% dexamethasone eye drops (Dexa group) after the uneventful surgeries. (springer.com)
Prompt administration of high-dose dexamethasone reduces mortality in patients with severe typhoid fever without increasing incidence of complications, carrier states, or relapse among survivors. (medscape.com)
We wish to extend this evidence in a study that aims to determine the efficacy and safety of atorvastatin combined with low-dose dexamethasone in patients with CSDH. (researchsquare.com)
19-22 We therefore initiated the second Atorvastatin combined with dexamethasone in Chronic subdural Haematoma (ATOCH-II) trial to determine the efficacy and safety of dexamethasone combined with low-dose atorvastatin in patients with CSDH. (researchsquare.com)
The primary aim of ATOCH-II is to determine whether the combination of low-dose atorvastatin and low-dose dexamethasone is superior to low-dose atorvastatin alone on the composite outcome of haematoma volume, transition to surgery, and death at 28 days in patients with CSDH. (researchsquare.com)
In patients with COVID-19 pneumonia in need of oxygen therapy or mechanical ventilation, dexamethasone 6 mg per day is currently recommended. (biomedcentral.com)
REMED is a prospective, open-label, randomised controlled trial testing the superiority of dexamethasone 20 mg (dexamethasone 20 mg on days 1-5, followed by dexamethasone 10 mg on days 6-10) vs 6 mg administered once daily intravenously for 10 days in adult patients with moderate or severe ARDS due to confirmed COVID-19. (biomedcentral.com)
There are several case reports of patients developing prolonged hiccups after chemotherapy administration, including dexamethasone. (lww.com)

In another study, eight healthy subjects were given dexamethasone 1 mg orally and tetracosactide [an adrenocorticotropic hormone (ACTH) analogue] 0.25 mg i.v., on separate occasions. (lu.se)

Only clinicians familiar with these methods of administration and with management of potential complications should administer dexamethasone by these routes. (pdr.net)

It is unclear whether dexamethasone in this condition is significantly better than other glucocorticoids. (wikipedia.org)
OBJECTIVES: The present experimental study was designed to clarify the effects of dexamethasone (DEXA) and isoflupredone (ISO), as the most common glucocorticoids in large animal medicine, on bovine thyroid hormones. (ac.ir)

Dexamethasone is a steroid drug. (sciencedaily.com)

Dexamethasone is a glucocorticoid medication used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), and along with antibiotics in tuberculosis. (wikipedia.org)
Dexamethasone is an effective glucocorticoid, a hormone related to cortisone. (petcarerx.com)

Dexamethasone may decrease the likelihood of mortality in severe typhoid fever cases complicated by delirium, obtundation, stupor, coma, or shock if bacterial meningitis has been definitively ruled out by cerebrospinal fluid studies. (medscape.com)
The steroid dexamethasone was found to reduce mortality, according to a study in the United Kingdom. (npr.org)

Each ml of Dexamethasone Injection contains 2 mg dexamethasone. (valleyvet.com)
Dexamethasone Injection is recommended for IM or IV administration. (valleyvet.com)
Dexamethasone sodium phosphate solution for injection 4 mg/mL or 10 mg/mL may be given directly from the vial. (pdr.net)
Dexamethasone sodium phosphate solution for injection 4 mg/mL may be administered into joints, soft tissues, or lesions, but administration of dexamethasone via these routes requires specialized techniques. (pdr.net)
Dexamethasone sodium phosphate injection is particularly recommended for use in conjunction with one of the less soluble, longer-acting steroids for intra-articular and soft tissue injection. (pdr.net)

medical citation needed] Dexamethasone is commonly given as a treatment for croup in children, as a single dose can reduce the swelling of the airway to improve breathing and reduce discomfort. (wikipedia.org)
In addition, dexamethasone treatment reduced IL-1 β . (hindawi.com)
Steroids are the standard first line treatment, with either 6‐week courses of tapering prednisone or repeated courses of high dose dexamethasone providing equivalent efficacy. (mja.com.au)
Dexamethasone is used in the treatment of myositis, arthritis, dermatitis, allergies and supportive therapy in all animals. (petcarerx.com)
Dexamethasone treatment has its downsides. (npr.org)
The resotration by dexamethasone treatment of the PNMT activity in medullas of hypophysectomized animals is blocked by concurrent administration of actinomycin D or puromycin. (aspetjournals.org)

Our objective was to investigate whether steroid administration could decrease the circulating levels of muscle proteins and modify myoelectric indexes of sarcolemmal excitability and fatigability. (qxmd.com)

Magnetic resonance imaging (MRI) of the pituitary, the corticotropin-releasing hormone (CRH) test and the high-dose dexamethasone suppression test are the main tests for the differential diagnosis of ACTH-dependent Cushing's syndrome. (scielo.br)
Dexamethasone is an exogenous steroid that provides negative feedback to the pituitary to suppress the secretion of ACTH . (wikidoc.org)
however, polysome patterns revert to normal if animals are treated with ACTH or dexamethasone. (aspetjournals.org)

Each tablet contains 4 mg dexamethasone. (medicines.org.uk)
Dexamethasone comes as a tablet and a solution to take by mouth. (medlineplus.gov)

RESULTS: Levels of T3 and T4 were decreased significantly after both drugs administrations. (ac.ir)
There were no significant changes in serum fT3 and fT4 levels following drugs administrations. (ac.ir)
tell your doctor and pharmacist if you are allergic to dexamethasone, aspirin, tartrazine (a yellow dye in some processed foods and drugs), or any other drugs. (medlineplus.gov)

Monoclonal antibody (mAb) therapies against SARS-CoV-2, the virus that causes COVID-19, initially received Emergency Use Authorization (EUA) from the Food and Drug Administration (FDA) in November 2020. (cdc.gov)

The co-administration of dexamethasone and nimesulide reduces pain, edema and trismus in third molar removal surgeries. (bvsalud.org)

Dexamethasone can increase the antiemetic effect of 5-HT3 receptor antagonists, such as ondansetron. (wikipedia.org)

People with cancer undergoing chemotherapy are often given dexamethasone to counteract certain side effects of their antitumor treatments. (wikipedia.org)
Cancer can be counted as one of the most severe diseases that is causing a large population of pets to suffer all over the world and the compound Dexamethasone can be used to relieve some of its symptoms. (petcarerx.com)
Dexamethasone is also used to treat certain types of cancer. (npr.org)

The data are sparse, but the authors of this article agree with the WHO that dexamethasone should be used in cases of severe typhoid fever. (medscape.com)
Dexamethasone, which has been shown to reduce risk of death in adults with COVID-19, is suggested for children with more severe disease who require breathing support. (news-medical.net)

One hundred seventy-three dexamethasone and 203 prednisone subjects completed the study regimen and telephone follow-up. (nih.gov)

Edema and trismus presented lower values during the administration of the two treatments. (bvsalud.org)

needs update] Dexamethasone has also been used with antibiotics to treat acute endophthalmitis. (wikipedia.org)

In explaining the decision to give the president dexamethasone, Conley said he was concerned by the two occasions when tests indicated the president's lungs weren't providing sufficient oxygen to his bloodstream. (npr.org)

Dexamethasone intravitreal steroid implants have been approved by the US Food and Drug Administration (FDA) to treat ocular conditions such as diabetic macular edema, central retinal vein occlusion, and uveitis. (wikipedia.org)
In brain tumors (primary or metastatic), dexamethasone is used to counteract the development of edema, which could eventually compress other brain structures. (wikipedia.org)
Dexamethasone does not reduce pain when administered alone, but acts in edema and postoperative trismus reduction. (bvsalud.org)

The effects of dexamethasone are frequently seen within a day and last for about three days. (wikipedia.org)
13 Dexamethasone had shown some effect on CSDH, but it is also complicated by adverse effects, particularly at high dose. (researchsquare.com)
Dexamethasone makes your stomach and intestines more susceptible to the irritating effects of alcohol, aspirin, and certain arthritis medications: this effect increases your risk of ulcers. (medlineplus.gov)
Dexamethasone may cause side effects. (medlineplus.gov)
Because of the potential clinical implications of these observations, studies are needed to determine the effects of dexamethasone on haematopoiesis in preterm infants. (bmj.com)

Dexamethasone (1 mg/kg) and isoflupredone (1 mg/kg) were administered intramuscularly in DEXA and ISO groups, respectively, for two consecutive days. (ac.ir)

Dexamethasone is made by a group of highly reputable and experienced scientists. (petcarerx.com)

Of these medications, dexamethasone has been reported most frequent as a causative agent in persistent/intractable hiccups. (lww.com)

For ophthalmic suspensions, shake well prior to each administration. (pdr.net)
For administration by the physician at the end of the ophthalmic surgical procedure. (pdr.net)

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