• Sedative analgesics such as remifentanil and dexmedetomidine have been demonstrated in studies to improve the impact of local nerve block and extend the duration of analgesia and have therefore become important adjuvants during surgical anesthesia. (hindawi.com)
  • In comparison to general anesthesia, brachial plexus block is easier to administer, requires less anesthetic medication, has a minimal effect on the entire body, maintains stable circulation, and provides prolonged postoperative analgesia compared to local infiltration anesthesia, and the analgesic effect and intraoperative treatment are superior. (hindawi.com)
  • Local anesthetic is often combined with other drugs to potentiate or prolong the analgesia produced by the nerve block. (wikipedia.org)
  • Regional blocks can be used for procedural anesthesia, post-operative analgesia, and treatment of acute pain in the emergency room. (wikipedia.org)
  • The retro bulbar can provide adequate anesthesia, akinesia and control of intraocular pressure as well as postoperative analgesia [ 3 ]. (longdom.org)
  • Long-acting local anesthetics (e.g., bupivacaine, levobupivacaine, and ropivacaine) generally provide analgesia of similar duration for 24 hours or less (20-23). (edmariano.com)
  • Of the available adjuvants, clonidine has been demonstrated in clinical studies and systematic reviews to extend the duration of analgesia for intermediate-acting local anesthetics (e.g., mepivacaine) with few side effects in doses up to 150 mcg but probably do not extend long-acting local anesthetics (25,27). (edmariano.com)
  • In order to explore the reliable clinical anesthesia effect, this paper uses experimental investigation methods to study the effect of dexmedetomidine in clinical surgery of replantation of severed fingers. (hindawi.com)
  • Finally, this paper verifies the reliability of dexmedetomidine in replantation of severed finger through comparative analysis and verifies that the anesthesia method proposed in this paper has certain user satisfaction through parameter survey. (hindawi.com)
  • The conventional dose of remifentanil combined with dexmedetomidine anesthesia has a good anesthetic effect in clinical applications, but at the same time, drug-related side effects are strong, and even excessive sedation of patients occurs, which is not conducive to patient safety [ 4 ]. (hindawi.com)
  • Does Dexmedetomidine Have a Perineural Mechanism of Action When Used as an Adjuvant to Ropivacaine? (silverchair.com)
  • Dexmedetomidine, magnesium sulphateand rocuronium bromidehave been added to local anesthetics to achieve such goal. (longdom.org)
  • Adding Mg to local anesthetic mixture in peribulbar anesthesia resulted in a fast onset, long duration and better akinesia score while Dexmedetomidine supplementation offered more patient satisfaction. (longdom.org)
  • To maintain an effective, consistent, and continuous level of sedation, we compared dexmedetomidine and propofol infusion in patients requiring monitored anesthesia care (MAC) for chemoport insertion. (jicajournal.in)
  • General anesthetic, local infiltration anesthesia, and brachial plexus block are the most used anesthetic procedures for finger replantation at the moment. (hindawi.com)
  • Local infiltration anesthetic, on the other hand, is not suited for long-term hand surgery since it cannot break during the procedure and alleviate the tourniquet discomfort. (hindawi.com)
  • Wound infiltration with other long-acting local anaesthetics was permitted. (bvsalud.org)
  • It is done under local infiltration along with monitored anesthesia care with sedation. (jicajournal.in)
  • These adjuvants may include epinephrine (or more specific alpha-adrenergic agonists), corticosteroids, opioids, or ketamine. (wikipedia.org)
  • Epinephrine when added to local anesthetic solutions provides vasoconstriction to decrease uptake but has little or no clinical effect on the duration of longer-acting local anesthetics (24). (edmariano.com)
  • There has been increasing interest in dexamethasone as an adjuvant to local anesthetic solutions based on clinical reports of extended duration when added to intermediate-acting local anesthetics (28,29). (edmariano.com)
  • Intravenous (IV) anesthetics were first discovered for their clinical utility in 1656 by Sir Christopher Wren, an architect, physicist, and astronomer at the University of Oxford while using a goosequill to inject opium into a dog to produce sleep [1]. (cambridge.org)
  • Clinical Anesthesia , 8th ed. (cambridge.org)
  • Although endodontic treatment should be view from a surgical perspective, because local therapy must be firstly instituted, many clinical situations require the use of systemic drugs to act on problems coming from the treatment sequence, such as: inflammatory reaction, pain, and infection that provide more comfort and safety to patient 5 . (bvsalud.org)
  • There are few protocols for the use of 200 mg (200 mg/10 mL vial), diluted in 250 intravenous (IV) lidocaine as an adjuvant in ccs of 0.9 % saline solution to be given intra- the relief of neuropathic pain, such as the venously in one hour by continuous infusion pain guidelines of the Latin American Feder- pump by the attending physician. (bvsalud.org)
  • Brachial plexus block commonly used in finger replantation has the advantages of simple operation, small side effects, and stable circulation, but it has inherent problems such as imperfect block range, slow onset of anesthesia, and short maintenance time of anesthesia. (hindawi.com)
  • It does, however, have flaws such as a limited block range, a sluggish onset of anesthesia, and a short duration of anesthesia. (hindawi.com)
  • A wide variety of additives have been used in a mixture with local anesthetics in PBA to fasten the onset, increase the potency and prolong the duration of the block to cover the long viteroretinalsurgeries. (longdom.org)
  • Many believe that the peribulbar block is a safer technique however, it has the disadvantage of a slow onset of orbital akinesia and to produce it a larger volume or repeated injections of anesthetic solution is required due to limited diffusion of local anesthetics (LA) [ 5 ]. (longdom.org)
  • local anesthetic medication interrupts nerve transmission, so patients experience decreased sensation. (edmariano.com)
  • Local anesthetic nerve block (sometimes referred to as simply "nerve block") is a short-term block, usually lasting hours or days, involving the injection of an anesthetic, a corticosteroid, and other agents onto or near a nerve. (wikipedia.org)
  • Local anesthetic nerve block (local anesthetic regional nerve blockade, or often simply nerve block) is a short-term nerve block involving the injection of local anesthetic as close to the nerve as possible for pain relief. (wikipedia.org)
  • The local anesthetic bathes the nerve and numbs the area of the body that is supplied by that nerve. (wikipedia.org)
  • Local anesthetic nerve blocks are sterile procedures that are usually performed in an outpatient facility or hospital. (wikipedia.org)
  • Nerve blocks (also referred to as "regional anesthesia") offer patients many potential advantages in the immediate postoperative period such as decreased pain, nausea and vomiting, and time spent in the recovery room (1,2). (edmariano.com)
  • Continuous peripheral nerve block (CPNB) techniques (also known as perineural catheters) permit delivery of local anesthetic solutions to the site of a peripheral nerve on an ongoing basis (5). (edmariano.com)
  • Several different drugs have been investigated for their potential to extend single-injection peripheral nerve block duration when added to local anesthetic solutions. (edmariano.com)
  • General anesthesia can address the need for a longer operation duration for severed finger replantation while also providing a superior anesthetic effect. (hindawi.com)
  • As a result, developing a proper anesthetic strategy to increase the anesthetic effect is critical for the operation's successful completion. (hindawi.com)
  • At the completion of the local anesthetic infusion, perineural catheters must be removed. (edmariano.com)
  • There are, however, a variety of general anesthetic medicines that might produce hemodynamic abnormalities. (hindawi.com)
  • Furthermore, studies have shown that using general anesthesia for upper limb surgery increases the risk of deep vein thrombosis while simultaneously increasing the expense of general anesthesia. (hindawi.com)
  • As a result, in the replantation of severed fingers, basic general anesthesia is seldom employed. (hindawi.com)
  • Consequently they can be an alternative to general anesthesia as well as oral pain medications. (wikipedia.org)
  • Vitreoretinal surgery is a surgery involving the vitreous and retina, they are lengthy procedures and associated with significant pain [ 1 ], it has traditionally been performed under general anesthesia but local anesthesia has increased in popularity in recent years [ 2 ]. (longdom.org)
  • BACKGROUND: Cauda Equina Syndrome (CES) after Combined Spinal-Epidural Anesthesia (CSEA) is a rare disease that most of the time need surgery to relieve spinal cord compression. (bvsalud.org)
  • Anesthesia and surgery were uneventful. (bvsalud.org)
  • Portable infusion devices can deliver a solution of plain local anesthetic for days after surgery, often with the ability to titrate the dose up and down or even stop the infusion temporarily when patients feel too numb (6,7). (edmariano.com)
  • Key considerations for appropriate use of antibiotics in the ICU include patient factors, pathogen susceptibility, and local resistance patterns. (jicajournal.in)
  • Lower limb surgeries could be performed under local, neuroaxial and general anesthesia, but neuroaxial block is the preferred method. (medscape.com)
  • Consequently they can be an alternative to general anesthesia as well as oral pain medications. (wikipedia.org)
  • Advantages over general anesthesia include faster recovery and less need for monitoring. (wikipedia.org)
  • The SG group received SAPB on the operative side before general anesthesia, and the RSG group received RSGB+ SAPB on the operative side before general anesthesia. (bvsalud.org)
  • [ 4 ] Dexmedetomidine has been widely used for anesthesia and analgesic purposes. (medscape.com)
  • Objectives: To assess and compare the effects of dexmedetomidine and fentanyl as adjuvants to epi-dural bupivacaine in lower limb and lower abdominal surgeries Materials and Methods: This randomized prospective study was conducted in a referral teaching hospital in Kolar, Karnataka. (researcher.life)
  • With this background, in our study we have compared Dexmedetomidine with Buprenorphine as an adjuvant to 0.5% levobupivacaine in spinal anesthesia in patients undergoing infraumbilical surgeries. (anesthesiologypaper.com)
  • Dexmedetomidine as an adjuvant to 0.5% levobupivacaine in spinal anesthesia produces longer duration of sensory and motor block but takes slightly more time to attain complete motor block as compared to Buprenorphine. (anesthesiologypaper.com)
  • Conclusion: In our study we concluded that dexmedetomidine is better adjuvant as compared to fentanyl in combined spinal epidural anaesthesia with intrathecal bupivacaine. (easpublisher.com)
  • Adjuvants added to local anaesthetics improve the quality of epidural block and prolong block-ade. (researcher.life)
  • The present study was undertaken to assess the analgesic efficacy of butorphanol (2mg) and tramadol (100 mg) as an adjuvant to levobupivacaine in supraclavicular brachial plexus block during perioperative period. (ijrajournal.com)
  • 4] Bajwa SS, Kaur J. Clinical profile of levobupivacaine in regional anesthesia: A systematic review. (ijrajournal.com)
  • 7] Kumari A, Chhabra H, Gupta R, Kaur H. Comparative Study of Effectiveness of Tramadol and Butorphanol as Adjuvants to Levobupivacaine for Supraclavicular Brachial Plexus Block. (ijrajournal.com)
  • 8] Foster RH, Markham A. Levobupivacaine: A review of its pharmacology and use as a local anaesthetic Drugs. (ijrajournal.com)
  • Adjuvant Drugs for Peripheral Nerve Blocks: The Role of Alpha-2 Agonists, Dexamethasone, Midazolam, and Non-steroidal Anti-inflammatory Drugs. (ijrajournal.com)
  • 10] Desai N, Kirkham KR, Albrecht E. Local anaesthetic adjuncts for peripheral regional anaesthesia: A narrative review. (ijrajournal.com)
  • Review of adjuvants to local anesthetics in peripheral nerve blocks: Current and future trends. (ijrajournal.com)
  • Introduction: There are studies which infer that spinal anaesthesia can be prolonged after adding adjuvants to local anaesthetics or by oral premedication before the block is performed. (oaji.net)
  • Although endodontic treatment should be view from a surgical perspective, because local therapy must be firstly instituted, many clinical situations require the use of systemic drugs to act on problems coming from the treatment sequence, such as: inflammatory reaction, pain, and infection that provide more comfort and safety to patient 5 . (bvsalud.org)
  • Obezbolivanie pri khirurgicheskom lechenii gnoĭno-nekroticheskikh form «diabeticheskĭ stopy» [Anesthesia in surgical treatment of pyo-necrotic forms of diabetic foot]. (aaukr.org)
  • Local anesthesia for surgery on the foot: efficacy in the ischemic or diabetic extremity. (aaukr.org)
  • Its unique pharmacodynamics and pharmacokinetic properties allow the use of ketamine in various clinical settings including sedation, ambulatory anesthesia, and intensive care practices. (degruyter.com)
  • Given its respiratory and cardiovascular stability, ketamine is considered an ideal anesthetic drug, especially in prehospital and emergency department settings [ 1 ]. (degruyter.com)
  • Comparative analysis of the methods of anesthetic maintenance in patients with diabetes with the syndrome of diabetic foot requiring operative intervention. (aaukr.org)
  • Regional anesthesia and timely treatment for neuropathy in patients with pyonecrotic forms of the diabetic foot]. (aaukr.org)
  • Background: Regional anesthesia is defined as loss of sensation in a body produced by administration of anaesthetic agent to the nerves supplying that region. (easpublisher.com)
  • It has improved spinal anesthesia and reduced the anesthetic drug related side effects including pruritus, nausea and vomiting. (medscape.com)
  • Local anesthetic nerve block (sometimes referred to as simply "nerve block") is a short-term block, usually lasting hours or days, involving the injection of an anesthetic, a corticosteroid, and other agents onto or near a nerve. (wikipedia.org)
  • However, these adjuvants shorten the onset times of sensory and motor block to a similar extent. (ijrajournal.com)
  • Local anesthetic nerve blocks are sterile procedures that are usually performed in an outpatient facility or hospital. (wikipedia.org)