Adjuvant chemoradiotherapy versus with radiotherapy radiotherapy or concurrent chemoradiotherapy. Medical search. Frequent questions

Accelerated partial breast irradiation using intensity-modulated radiotherapy versus whole breast irradiation: 5-year survival analysis of a phase 3 randomised controlled trial. (srobf.cz)
2021 ). Cisplatin-based chemotherapy with intensity-modulated radiotherapy (IMRT) is the standard care for NPC patients in recent years. (researchsquare.com)
Intensity Modulated Radiotherapy (IMRT)for Whole Pelvic Radiation Therapy (WPRT) is considered superior to 3D conformal radiotherapy in dose distribution to targets and to spare normal tissue as (BM) supported by many dosimetric studies [ 7 ]. (oncologyradiotherapy.com)
At a time when modern radiation treatment like intensity-modulated radiotherapy (IMRT) are accomplishing great good local control, distant metastases are getting to be the transcendent design of treatment failure, particularly in patients with locally progressed illness. (intechopen.com)

For advanced diseases, CRT shows a better prognosis than RT alone, especially sequential CRT and concurrent chemoradiotherapy (CCRT) [ 5 - 7 ]. (e-crt.org)
The efficacy and safety of nimotuzumab (NTZ) added to concurrent chemoradiotherapy (CCRT) was investigated in patients with stage III-IVa nasopharyngeal carcinoma (NPC). (researchsquare.com)
Compared with NPC patients receiving CCRT alone, patients who received NTZ plus CCRT treatment had significantly better OS (5-year OS, 76.1% vs. 72.3%, P = 0.004), PFS (5-year PFS, 73.2% vs. 69.0%, P = 0.002), and LRFS (5-year LRFS, 73.2% vs. 69.0%, P = 0.028). (researchsquare.com)
According to the 2021 Chinese Society of Clinical Oncology and American Society of Clinical Oncology guidelines for nasopharyngeal carcinoma, concurrent chemoradiotherapy (CCRT) is still recommended as the standard treatment for stage II-IVa NPC patients (Yu-Pei Chen et al. (researchsquare.com)
Nasopharyngeal carcinoma (NPC) patients with N2-3 diseases are prone to develop distant metastasis even treated with standard concurrent chemoradiotherapy (CCRT). (oncotarget.com)
They were all treated with Intensity-modulated radiation therapy (IMRT) combined with systemic treatments, including radiotherapy alone (RT alone), neoadjuvant chemotherapy followed by radiotherapy (NACT+RT), CCRT, NACT+CCRT, NACT followed by radiotherapy and adjuvant chemotherapy (NACT+RT+AC), CCRT+AC and NACT+CCRT+AC. (oncotarget.com)
To compare patient survival outcomes between completion hysterectomy and conventional surveillance in locally advanced adenocarcinoma of the cervix after concurrent chemoradiotherapy (CCRT). (koreamed.org)

However, two patients treated with IMRT and neoadjuvant but without concurrent and adjuvant chemotherapy died of treatment related complications. (biomedcentral.com)
The rationale of concurrent chemotherapy with IMRT in the management of NPC was largely derived from experience with conventional radiotherapy. (biomedcentral.com)
The aim of this report is to address the treatment outcome and to elucidate the efficacy of concurrent chemotherapy in NPC treated with IMRT by analyzing the outcome of a relatively large group of patients with locoregionally advanced NPC treated uniformly with IMRT following neoadjuvant chemotherapy, with or without concurrent chemotherapy. (biomedcentral.com)
Aim: The main objective of this study was evaluation of bone marrow sparing IMRT versus standard IMRT as a planning limitation in cervical cancer therapy receiving concurrent chemo radiotherapy for evaluation of the response of treatment,toxicity profile and quality of life of both radiotherapy treatment modalities. (oncologyradiotherapy.com)
Evaluation of bone marrow sparing IMRT versus standard IMRT as a planning limitation in cervical cancer therapy cases receiving concurrent chemo radiotherapy. (oncologyradiotherapy.com)

Adjuvant chemotherapy for rectal cancer patients treated with preoperative (chemo)radiotherapy and total mesorectal excision: a Dutch Colorectal Cancer Group (DCCG) randomized phase III trial. (srobf.cz)
In 2004, a randomized trial from Germany was published establishing a regimen of preoperative chemoradiotherapy and surgery followed by additional cycles of chemotherapy alone as the standard of care for clinical stages T3 or T4, or for node-positive rectal cancer [ 3 ]. (biomedcentral.com)
Other clinical studies from the United States, Europe, and Asia have also influenced the treatment strategies for operable rectal cancer, as various approaches using preoperative or postoperative radiotherapy, with or without chemotherapy, have been examined. (biomedcentral.com)
This study was designed to explore whether an intensified chemoradiotherapy (CRT) led to a better clinical outcome in locally advanced rectal cancer. (biomedcentral.com)
He leads on the radiotherapy quality assurance programme for the UK rectal cancer trials. (cardiff.ac.uk)

Concurrent chemo-radiation with or without induction gemcitabine, Carboplatin, and Paclitaxel: a randomized, phase 2/3 trial in locally advanced nasopharyngeal carcinoma. (srobf.cz)
What is happening for at least N2 IIIa disease right now is a very important trial that accepts concomitant chemo-radiotherapy - that's the SWOG regimen, platinum, etoposide, radiation - and then asks, "Do these patients really need surgery? (cancerstreatment.com)
Do they benefit from that or is chemo-radiotherapy just as good? (cancerstreatment.com)
So they randomized on the standard arm to receive 45 gray of radiation with two cycles of platinum, etoposide and then surgery versus that same initial chemo-radiotherapy and then a chemo-radiotherapy boost. (cancerstreatment.com)
You would look at surgery and radiation, in some cases surgery alone, versus surgery, radiation and chemo. (cancerstreatment.com)
Concurrent chemo-radiotherapy is the usual treatment for locally advanced cervical cancer. (oncologyradiotherapy.com)
UK Cancer Centre experience of hysterectomy post chemo-radiotherapy treatment for cervical cancer. (koreamed.org)

A concomitant boost to oxalipatin-combined preoperative chemoradiotherapy demonstrated a slightly higher pCR rate but delayed incision healing after surgery. (biomedcentral.com)

A final analysis of data from the NRG258 trial, with a median follow-up of 112 months for overall survival, showed no significant difference between the two arms: the stratified ratio for death comparing chemoradiation therapy vs chemotherapy alone was 1.05 (log-rank two-sided P = .72). (medscape.com)
That study showed improved progression-free and overall survival in the chemoradiotherapy arm. (medscape.com)
For this study, Matei and colleagues hypothesized that systemic chemotherapy and tumor volume-directed radiotherapy would improve recurrence-free survival and overall survival in comparison with systemic chemotherapy alone for patients with surgically staged III/IVA uterine cancer. (medscape.com)
The number of patients getting radiation on the surgical arm is much higher and paradoxically we now think that adjuvant radiation for at least some of these patients actually decreases their chances of survival or cure rather than increasing it. (cancerstreatment.com)
The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction - a phase III trial of the German AIO/CAO-V/CAOGI. (helsedirektoratet.no)
Of the 10-20% of patients who present with resectable tumors, the 5-year surviva rate is still only about 20%, with a median survival of around 23-43 months with adjuvant therapy ( 2 - 4 ). (iiarjournals.org)
Furthermore, several randomised trials have shown that the addition of alkylating chemotherapy, either temozolomide or nitrosourea-based regimens, to radiotherapy results in prolonged survival. (smw.ch)
To evaluate the effect of timing of radiotherapy (RT) on survival in patients with newly diagnosed primary glioblastoma (GBM) treated with the same therapeutical protocol. (springer.com)
3,4 The investigators found a 3-year event-free survival of 86.1% among patients who received sintilimab vs 76.0% among patients who received standard of care (HR = 0.59). (ascopost.com)
A phase II study showed that patients with resected local-regionally advanced head and neck squamous cell carcinoma (HNSCC) had improved survival when pembrolizumab was added to adjuvant RT (NCT02641093). (nature.com)
However, the median survival time of GBM patients is still less than 15 months even after treatment with surgical resection, concurrent chemoradiotherapy, and adjuvant chemotherapy with TMZ (Ostrom et al. (excli.de)
We compared the progression-free survival (PFS) and overall survival (OS) between the patients with or without adjuvant hysterectomy. (koreamed.org)
Palliative Radiotherapy for Non-metastatic Non-small-cell Lung Cancer: Impact of Blood Test Results on Survival. (cdc.gov)

however, definitive radiation therapy, concurrent chemoradiation alone or after surgery, and induction therapy followed by concurrent chemoradation are alternative options for patients who are not candidates for surgery alone. (medscape.com)
Duration of androgen suppression before radiotherapy for localized prostate cancer: radiation therapy oncology group randomized clinical trial 9910. (srobf.cz)
Hyperfractionated accelerated radiation therapy (HART) of 70.6 Gy with concurrent 5-FU/Mitomycin C is superior to HART of 77.6 Gy alone in locally advanced head and neck cancer: long-term results of the ARO 95-06 randomized phase III trial. (srobf.cz)
The chemoradiotherapy regimen consisted of cisplatin (50 mg/m 2 ) on days 1 and 29 concurrent with volume-directed external-beam radiation therapy, followed by carboplatin given at a dose to achieve an area under the concentration-time curve (AUC) of 5-6 plus paclitaxel (175 mg/m 2 every 21 days for four cycles). (medscape.com)
A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer. (helsedirektoratet.no)
Numerous studies have demonstrated that chemotherapy concurrent to radiation therapy provides better tumor control and more favorable outcomes (M. X. Zhang et al. (researchsquare.com)
However, surgery is increasingly incorporated in a multimodality approach that includes neoadjuvant and adjuvant chemotherapy and/or radiation therapy. (medscape.com)
Planning Considerations for the Primary Lung Tumor Stereotactic Body Radiation Therapy Followed by Concurrent Mediastinal Radiotherapy for Locally-Advanced Non-Small Cell Lung Cancer. (medline.ch)
Daily Adaptive vs. Non-Adaptive External Beam Radiation Therapy with Concurrent Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer (NSCLC): A Prospective Randomized Trial of an Individualized Approach for Toxicity Reduction (ARTIA-Lung). (medline.ch)

The standard of care for patients with newly diagnosed GBM comprises maximum safe resection of the tumor followed by radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) chemotherapy [ 3 , 4 ]. (springer.com)
The typical clinical management strategy for patients with GBM is a multimodal approach that includes maximal safe resection, radiotherapy, and temozolomide (TMZ) therapy. (excli.de)

The purpose of this study is to evaluate the efficacy and safety of pembrolizumab plus concurrent chemoradiotherapy compared to placebo plus concurrent chemoradiotherapy in participants with locally advanced cervical cancer. (msdoncologyclinicaltrials.com)
The current global, randomised, double-blind, phase 3 LEAP-002 trial ( NCT03713593 ), presented by Prof. Richard Finn (David Geffen School of Medicine, CA, USA) evaluated the efficacy of lenvatinib plus pembrolizumab versus lenvatinib plus placebo as first-line therapy for advanced HCC [3]. (medicom-publishers.com)
At 24 months, 16.7% of participants treated with lenvatinib plus pembrolizumab were progression-free versus 9.3% of patients treated with lenvatinib plus placebo. (medicom-publishers.com)
The disease control rate was 81.3% in the lenvatinib plus pembrolizumab arm (26.1% objective response rate [ORR]) versus 78.4% (17.5% ORR) in the lenvatinib plus placebo arm. (medicom-publishers.com)
Primary results from the phase III LEAP-002 study: Lenvatinib plus pembrolizumab versus lenvatinib as first-line (1L) therapy for advanced hepatocellular carcinoma (aHCC). (medicom-publishers.com)
Prediction of Response to Neoadjuvant Chemoradiotherapy Combined with Pembrolizumab in Esophageal Squamous Cell Carcinoma with CT/FDG PET Radiomic Signatures Based on Machine Learning Classification. (medline.ch)

The current standard of care for locally advanced nasopharyngeal carcinoma of gemcitabine/cisplatin induction followed by concurrent chemoradiotherapy was established by Zhang et al in 2019. (ascopost.com)
Platinum-based concurrent chemoradiotherapy represents the gold standard in the treatment of locally advanced nasopharyngeal carcinoma (NPC) [ 1 , 2 ] in the era of 2D radiotherapy. (oncotarget.com)

Cancer cell lines were selected from lung and cervical cancer cell line that are commonly used for stereotactic body radiotherapy and effective with methotrexate. (frontiersin.org)
1. Kokka F, Bryant A, Brockbank E, Powell M, Oram D. Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer. (koreamed.org)
5. Platt SL, Patel A, Humphrey PJ, Al-Booz H, Bailey J. Completion surgery after chemoradiotherapy for cervical cancer - is there a role? (koreamed.org)
Results of surgery after concurrent chemoradiotherapy in advanced cervical cancer: comparison of extended hysterectomy and extrafascial hysterectomy. (koreamed.org)

Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study. (srobf.cz)

The CONTINUUM trial randomly assigned 425 patients in China with stage III/IV nasophargyneal carcinoma to receive gemcitabine/cisplatin induction followed by concurrent chemoradiotherapy with or without sintilimab, a novel PD-1 antibody with a higher affinity for PD-1 than other immune checkpoint inhibitors. (ascopost.com)

Therefore, we designed this randomized trial to explore whether a combined regimen of oxaliplatin-added chemoradiotherapy and a concomitant boost to the primary tumor would further lead to a better clinical outcome. (biomedcentral.com)

Historically, after surgical resection adjuvant therapy would be delivered if high-risk features were discovered upon pathologic examination of the surgical specimen. (biomedcentral.com)
Patients and Methods: We conducted a retrospective study of 63 patients diagnosed from 2004-2013 with histopathologically-confirmed stage I/II pancreatic cancer treated with a surgical resection followed by adjuvant concurrent chemoradiation to at least 45 Gy using 3D planning and capecitabine at 1,600 mg/m 2 /day (Monday-Friday) for 6 weeks. (iiarjournals.org)
With regards to treatment, the role of surgical resection, radiotherapy, chemotherapy, and tumor-treating fields will be presented. (cancernetwork.com)

This has been piloted in 94 patients with an objective response rate of the chemotherapy of 54%, which is not bad, and based on this the phase III trial has been activated where patients received either surgery or induction, not adjuvant, carbo and paclitaxel for three cycles. (cancerstreatment.com)
1 - 3 In patients with node-negative small tumors, chemotherapy burden can be de-escalated by administering weekly paclitaxel for 3 months and concurrent trastuzumab for 1 year. (jnccn.org)
2023. Efficacy of early PET-CT directed switch to carboplatin and paclitaxel based definitive chemoradiotherapy in patients with oesophageal cancer who have a poor early response to induction cisplatin and capecitabine in the UK: a multi-centre randomised controlled phase II trial . (cardiff.ac.uk)
Chemoradiotherapy Combined with Nab-Paclitaxel plus Cisplatin in Patients with Locally Advanced Borderline Resectable or Unresectable Esophageal Squamous Cell Carcinoma: A Phase I/II Study. (medline.ch)

The primary treatment regimen for NPCs is radiotherapy (RT) coupled with or without chemotherapy. (e-crt.org)

Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial. (helsedirektoratet.no)
Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial. (helsedirektoratet.no)
Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): a phase 3 open-label, randomised controlled trial. (helsedirektoratet.no)
We aimed to evaluate the safety and efficacy of adding capecitabine (a known radiosensitizer by direct and abscopal effects) to concurrent radiation in the adjuvant setting after resection of pancreatic adenocarcinoma. (iiarjournals.org)
Conclusion: Concurrent chemoradiation using capecitabine as a radiosensitizer in the adjuvant setting for pancreatic cancer was completed by the vast majority of patients in this series. (iiarjournals.org)
The most commonly reported grade 3-4 AEs with capecitabine versus observation included HFS (9% versus 0), neutropaenia (4% versus 3%), and leukopenia (3% each arm). (ogkologos.com)
The investigators wrote that, to their knowledge, this is the first randomised phase III study to assess the efficacy and safety of adding metronomic capecitabine as an adjuvant therapy to chemoradiotherapy in patients with high-risk locoregionally advanced NPC. (ogkologos.com)

Use of thoracic radiotherapy for extensive stage small-cell lung cancer: a phase 3 randomised controlled trial. (srobf.cz)
Long-Term Results of a Phase II Study of Accelerated Hyperfractionated Thoracic Radiotherapy with Dose Escalation to 54 Gy for Limited-Stage Small-Cell Lung Cancer. (medline.ch)

Concurrent chemoradiation therapy is the current standard of care for patients with locally advanced squamous cell carcinoma of the head and neck. (medscape.com)
The decision to treat the patient with concurrent chemoradiation therapy rather than surgery, radiation, or chemotherapy individually should be made by a multidisciplinary tumor board (including a medical oncologist, a radiation therapist, and an ENT surgeon). (medscape.com)
For locoregionally-advanced diseases, concurrent chemoradiation therapy is considered the standard of treatment. (biomedcentral.com)

Local and distant recurrence rates after non-total mesorectal excision (TME) surgery alone are as high as 40%-60% [ 2 ], thus warranting adjuvant therapy to improve local/regional control. (biomedcentral.com)

Great EGFR appearance was connected with radiotherapy and chemotherapy level of resistance, and increased dangers of locoregional recurrence, faraway metastasis, and poor prognosis [7, 8]. (healthy-nutrition-plan.com)
The study investigators noted that disease recurrence is common in patients with loco-regional advanced NPC achieving remission following first-line treatment with the standard of care, concurrent cisplatin-radiotherapy with or without induction chemotherapy. (ogkologos.com)
Hysterectomy was associated with a lower rate of locoregional recurrence but did not reach statistical significance (5.13% vs. 13.5%, p=0.067). (koreamed.org)
Adjuvant radiation following clear margin resection of high T-stage cutaneous squamous cell carcinoma halves the risk of local and locoregional recurrence: A dual-center retrospective study. (dana-farber.org)

Updated results from the Quarterback trial, presented at ASCO 2023, showed that response to induction chemotherapy may be a reasonable way to select patients for dose-reduced chemoradiotherapy, but further randomized studies are needed to evaluate this approach. (ascopost.com)
Over the decades Dr. Morrison has been involved in trials of fractionation, radiation protectors, induction and concurrent chemotherapy, and proton beam therapy. (mdanderson.org)

On the basis of this background, we retrospectively explored the possible treatment option and hypothesized that patients with bulky lymph nodes would benefit from additional chemotherapy other than the concurrent modality. (oncotarget.com)

Background: This phase 2 prospective randomized double-arm study carried out at Clinical Oncology Department Tanta University, Radiotherapy Department, NCI, Cairo University and Gharbia cancer society through the period from May 2018 to December 2019 and enrolled 60 patients with cervical carcinoma. (oncologyradiotherapy.com)

However, there are limited effective non-invasive image modalities for the early prediction of tumor response to chemoradiotherapy (CRT). (e-crt.org)
Newer treatment modalities, including different sequences and combos of chemoradiotherapy are explored. (healthy-nutrition-plan.com)
According to the systemic treatment modalities delivered, we classified all 547 patients into non-adjuvant chemotherapy (non-AC) group (341 patients) and adjuvant chemotherapy (AC) group (206 patients). (oncotarget.com)

We examined expression levels of organic anion-transporting polypeptide (OATP)1B1, OATP1B3, OATP1B7, and organic anion transporter (OAT)1 as solute carrier transporters and multidrug resistance-associated protein (MRP)1 and MRP2 as ATP-binding cassette transporters, using real-time polymerase chain reaction and accumulation of 3 H-MTX in cancer cells after 10-Gy irradiation, assuming stereotactic body radiotherapy. (frontiersin.org)

The addition of adjuvant chemotherapy seemed to provide benefits to patients with N3 stage NPC and the current study may indicate the need for further randomized investigation. (oncotarget.com)

Randomized trial comparing surgery and adjuvant radiotherapy versus concurrent chemoradiotherapy in patients with advanced, nonmetastatic squamous cell carcinoma of thehead and neck: 10-year update and subset analysis. (srobf.cz)

He is chair of the National Cancer Research Institute CTRad WS2 (UK radiotherapy research) subgroup and the Clinical Expert Review Panel for CRUK. (cardiff.ac.uk)

Alcohol and tobacco were significant risk factors (p: 0.002 vs. p: 0.002 respectively). (bvsalud.org)

One of these is the PORTEC-3 trial, which investigated adjuvant chemoradiotherapy vs pelvic radiotherapy alone for women with high-risk endometrial cancer. (medscape.com)
In pelvic malignancy treated with CHTRT, bone marrow sparing radiotherapy is an option to minimize toxicity [ 6 ]. (oncologyradiotherapy.com)

2022. Spend less to achieve more: Economic analysis of intermittent versus continuous cetuximab in KRAS wild-type patients with metastatic colorectal cancer . (cardiff.ac.uk)

To conclude, concurrent administration of chemoradiation and nimotuzumab was well-tolerated with great compliance. (healthy-nutrition-plan.com)

High-grade glioma (HGG) are optimally treated with maximum safe surgery, followed by radiotherapy (RT) and/or systemic chemotherapy (CT). (surgicalneurologyint.com)

Preliminary scientific outcome data show up encouraging with advantageous normal tissues toxicity results evaluating with traditional data of concurrent chemoradiation plus cetuximab. (healthy-nutrition-plan.com)

Clinical use of a combination of radiotherapy and chemotherapy continues to increase, while the development of immunotherapy, such as checkpoint inhibitors, offers hope in improving treatment outcome. (hkmj.org)
Nevertheless, the occurrence of acne-like allergy and radiotherapy-related severe pores and skin and mucosal harmful effects was considerably increased, therefore its clinical software was significantly limited. (healthy-nutrition-plan.com)
There are limited data of randomized clinical trials with adjuvant chemotherapy to support evidence-based decision-making [ 6 - 8 ]. (oncotarget.com)
Pinna R, Campus G, Cumbo E, Mura I, Milia E. Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage. (ac.ir)
HR of completion surgery vs. surveillance for PFS and OS in specified clinical features. (koreamed.org)
Characterization of clinical outcomes after shorter course hypofractionated and standard-course radiotherapy for stage I-III curatively-treated Merkel cell carcinoma. (dana-farber.org)

At 60 months, the percentage of patients alive and relapse free was 59% in the chemoradiotherapy group and 58% in the chemotherapy-only group (hazard ratio [HR], 0.90). (medscape.com)

More than half of Korean lung cancer patients undergo chemotherapy, including adjuvant therapy. (bvsalud.org)
The National Comprehensive Cancer Network (NCCN) guidelines have been updated recently for targeted therapy of multiple gene mutations, and targeted therapy is used not only for chemotherapy but also for adjuvant therapy. (bvsalud.org)

It is characterized by a relatively high sensitivity to radiotherapy and chemotherapy (Y. Zhang et al. (researchsquare.com)

As one of the four major means of cancer treatment including surgery, radiotherapy (RT), chemotherapy, immunotherapy, RT can be applied to various cancers as both a radical cancer treatment and an adjuvant treatment before or after surgery. (nature.com)
Radiotherapy Dose in Patients Receiving Immunotherapy. (dana-farber.org)

High-dose radiotherapy with short-term or long-term androgen deprivation in localised prostate cancer (DART01/05 GICOR): a randomised, controlled, phase 3 trial. (srobf.cz)
Stereotactic body radiotherapy (SBRT) is a single high-dose radiotherapy used to treat a variety of cancers. (frontiersin.org)

Ninety-five percent patients completed a full-dose chemoradiotherapy as planning. (biomedcentral.com)
Among the other studies chosen to be highlighted at the scientific session on breast cancer was a phase Ib trial to assess safety and toxicity and establish the maximum tolerated dose of concurrent cisplatin with adjuvant radiotherapy for women with stage II and II triple-negative breast cancer. (ascopost.com)

No Increased Risk of Second Cancer After Radiotherapy in Patients Treated for Rectal or Endometrial Cancer in the Randomized TME, PORTEC-1, and PORTEC-2 Trials. (srobf.cz)

The UK HeartSpare Study (Stage IB): Randomised comparison of a voluntary breath-hold technique and prone radiotherapy after breast conserving surgery. (srobf.cz)
Randomized phase III study of whole-brain radiotherapy for primary CNS lymphoma. (srobf.cz)
Acupuncture-Like Transcutaneous Electrical Nerve Stimulation Versus Pilocarpine in Treating Radiation-Induced Xerostomia: Results of RTOG 0537 Phase 3 Study. (srobf.cz)
However, the comparator was external-beam radiotherapy, and the study reaffirmed the role of chemotherapy for treating high risk endometrial cancer," she said. (medscape.com)
This was a prospective study carried out on people newly diagnosed with HNC requiring curative radiotherapy of more than 60 Gy. (ac.ir)
Radical Chemoradiotherapy vs. Radical Surgery plus Adjuvant Chemotherapy or Chemoradiotherapy in Locally Advanced Primary Small Cell Carcinoma of the Esophagus: A Multicenter Retrospective Study in China. (medline.ch)

Eligible patients had no loco-regional disease or distant metastasis after definitive chemoradiotherapy. (ogkologos.com)

Conventional fractionation for concurrent chemoradiation is up to 72 Gy (2.0 Gy/fraction). (medscape.com)

RTOG 9804: A Prospective Randomized Trial for Good-Risk Ductal Carcinoma In Situ Comparing Radiotherapy With Observation. (srobf.cz)

Anatomy3

Diseases41

Chemicals and Drugs28

Analytical, Diagnostic and Therapeutic Techniques and Equipment59

Phenomena and Processes4

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Humanities1

Information Science5

Health Care20

Intensity-modulated radiotherapy4

CCRT7

IMRT5

Rectal cancer5

Chemo7

Preoperative chemoradiotherapy1

Survival13

Radiation therapy9

Temozolomide2

Pembrolizumab6

Nasopharyngeal2

Cervical cancer4

Conformal radiotherapy1

Gemcitabine1

Concomitant1

Surgical3

Paclitaxel4

Regimen1

Capecitabine7

Thoracic radiotherapy2

Chemoradiation therapy3

Total mesorect1

Recurrence4

Induction2

Modality1

20181

Modalities3

Irradiation1

Further randomized1

Squamous cell carc1

Subgroup1

0.0021

Pelvic2

20221

Nimotuzumab1

Systemic chemotherapy1

Cetuximab1

Clinical6

Hazard ratio1

Therapy2

Zhang1

Immunotherapy2

High-dose2

Dose2

Trials1

Study6

Definitive1

Fractionation1

Observation1