Adjusted dose. Medical search. Frequent questions

However, fixed doses versus placebo are probably not inferior to weight-adjusted doses of BZN versus placebo in terms of parasitological efficacy and safety . (bvsalud.org)
The relative infant dose on a weight-adjusted maternal daily dose would be approximately 2. (angelfire.com)
One hundred three patients undergoing coronary intervention received abciximab (0.25 mg/kg bolus, 10 μg/min infusion for 12 hours) and aspirin and were randomized by a 2 x 2 factorial design to 1 of 2 weight-adjusted heparin doses and to 1 of 2 strategies for heparin discontinuation and vascular sheath removal. (houstonmethodist.org)
While most published studies have assessed the effectiveness of a prophylactic phenylephrine fixed dose infusion, few studies have assessed the effect of a prophylactic phenylephrine weight adjusted dose infusion on maintaining maternal hemodynamic stability following spinal anesthesia for a cesarean delivery. (aku.edu)
Objective: To compare the incidence of hypotension between women undergoing elective caesarean section under spinal anaesthesia, receiving prophylactic phenylephrine infusion at a fixed dose of 37.5 micrograms per minute versus a weight adjusted dose of 0.5 micrograms per kilogram per minute. (aku.edu)
There was a 35.2% incidence of hypotension in the fixed dose group and an 18.6% incidence of hypotension in the weight adjusted dose group. (aku.edu)
Conclusion: Among this population, the incidence of hypotension was significantly less in the weight adjusted dose group than in the fixed dose group. (aku.edu)
Administering prophylactic phenylephrine infusion at a weight adjusted dose of 0.5 micrograms per kilogram per minute results in a lower incidence of hypotension compared to its administration at a fixed dose of 37.5 micrograms per minute. (aku.edu)

No dose adjustment is necessary in infants with mild to moderate hepatic impairment. (who.int)
In the presence of mild to moderate renal or hepatic impairment, adjustment of dosing is not required for treatment of gout flare, prophylaxis of gout flare and FMF, but patients should be monitored closely ( 8.6 ). (nih.gov)

Now, we can further optimize glycemic control by using CGM trend arrows to fine-tune insulin doses," Dr Laffel told Medscape Medical News . (medscape.com)
However, they apply only to the Dexcom G5 system, which was approved in December 2016 by the US Food and Drug Administration for "nonadjunctive" insulin dosing, thereby eliminating the need for confirmatory finger-stick blood glucose testing in calculating insulin doses. (medscape.com)
Four previous papers have addressed the incorporation of CGM trend arrows in the calculation of insulin doses along with the actual current blood glucose level, anticipated carbohydrate consumption, exercise, and other factors. (medscape.com)
Diabetics may have to adjust insulin doses. (brighthub.com)

The weight-of evidence evaluations are qualitative in nature, although ATSDR recognizes that observations of toxicological interactions depend greatly on exposure doses and that some interactions appear to have thresholds. (cdc.gov)
for sustained parasitological clearance, it was 4.60 (95% CI 0.40-52.51), probably indicating at least non-inferior effect of fixed doses, with no statistically significant interactions by scheme for global and most subgroup estimations. (bvsalud.org)

If you take large doses for a long time, your doctor probably will decrease your dose gradually to allow your body to adjust before stopping the drug completely. (medlineplus.gov)
if you have a history of ulcers or take large doses of aspirin or other arthritis medication, limit your consumption of alcoholic beverages while taking this drug. (medlineplus.gov)
Medication such as large doses of salicylates, diuretics, anticonvulsants, and oral contraceptives affect the glucose tolerance test. (wikipedia.org)

In addition, one in five respondents takes higher doses or take several medications at the same time to relieve symptoms more quickly. (recipesandtips.com)
And while you may believe higher doses lead to better sleep, that's not exactly the case. (clevelandclinic.org)

Dose adjustment is required for diabetes patients with renal impairment taking combination products containing metformin. (mims.co.uk)
No dose adjustment is required for infants with creatinine clearance 20 ml/minute. (who.int)
in the 'low-dose heparin' group, an initial bolus of 70 U/kg was administered without adjustment for ACT. (houstonmethodist.org)
Reduction and weight adjustment of heparin dose and early sheath removal in the setting of platelet inhibition with abciximab during coronary intervention may be useful in diminishing the incidence of hemorrhagic complications without loss of clinical efficacy. (houstonmethodist.org)
See full prescribing information (FPI) for dose adjustment regarding patients with impaired renal function ( 2.5 ), impaired hepatic function ( 2.6 ), the patient's age ( 2.3 , 8.5 ) or use of coadministered drugs ( 2.4 ). (nih.gov)
In patients with severe renal impairment for prophylaxis of gout flares, the starting dose should be 0.3 mg/day for gout flares, no dose adjustment is required, but a treatment course should be repeated no more than once every two weeks. (nih.gov)
Newer oral anticoagulants have a slightly lower risk of intracranial hemorrhage compared with warfarin (Coumadin), but dose adjustment is required in patients with renal disease. (aafp.org)
However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for elderly patients receiving prednisone. (mayoclinic.org)

High-dose chemotherapy and autologous stem cell transplantation (HCT-ASCT) after high-dose methotrexate (MTX)-based immuno-chemotherapy has become an increasingly used treatment approach in eligible elderly PCNSL patients with promising feasibility and efficacy, but has not been compared with conventional chemotherapy approaches. (biomedcentral.com)
These results suggest that a third dose of BNT162b2 is safe, improves humoral immunity against SARS-CoV-2 and could be immunologically beneficial for patients with cancer on active chemotherapy. (nature.com)

CDC recommends that all persons aged 12 years receive a received a third dose in a primary series or a booster dose after booster dose of COVID-19 mRNA vaccine 5 months after a 2 dose primary series (including the reduced-dosage Moderna completion of a primary mRNA vaccination series and that booster). (cdc.gov)
This will include a review of the evidence to support that extended interval between a first and second mRNA COVID-19 vaccine doses. (cdc.gov)

18 years at various time points after receipt of a second or third ing the first 2 months following a third dose and decreased vaccine dose during two periods: Delta variant predominance to 78% 4 months after a third dose. (cdc.gov)
COVID-19 vaccine dose. (cdc.gov)
Health (Texas), Columbia University Irving Medical Center (New York), after receipt of the second dose for recipients of the Pfizer-BioNTech vaccine. (cdc.gov)

However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. (medlineplus.gov)
If your idling problems are the most confounding impasse I can timidly overtake for myself, so don't go riding just for your next dose, skip the accumulative dose and the moore of oral contraceptives and the moore of oral contraceptives and the joint pain? (angelfire.com)

These dose changes are based on the trend arrows according to the patient's insulin sensitivity. (medscape.com)
The dose can be adjusted according to the patient's response to the treatment, but should be kept within the range of 25 to 75 mg. (europa.eu)

In these patients, life-threatening and fatal colchicine toxicity has been reported with colchicine taken in therapeutic doses ( 7 ). (nih.gov)
A GLP test (Report No. DUPONT-20813, 2007) following OECD guideline 422 combined repeat dose toxicity study with the reproduction/development toxicity shows that exposure to the test substance did not result in adverse clinical signs or mortality. (europa.eu)
Daily doses of calcium folinate should be adjusted depending on the hematological toxicity of trimetrexate. (janusinfo.se)

myPTM allows you to self-administer bolus doses of morphine from your pump when needed and within limits set by your doctor. (medtronic.com)

Give total daily dose in one or two divided doses ( 2.2 ). (nih.gov)
Increase or decrease the dose as indicated and as tolerated in increments of 0.3 mg/day, not to exceed the maximum recommended daily dose ( 2.2 ). (nih.gov)
Calcium folinate can be administered either by the intravenous route at a dose of 20 mg/m2 for 5 to 10 minutes every 6 hours for a total daily dose of 80 mg/m2 or by oral route with four doses of 20 mg/m2 administered at equal time intervals. (janusinfo.se)

Neutralizing antibodies were detected in 67% of patients with cancer after the first immunization, followed by a threefold increase in median titers after the second dose. (nature.com)
Administer the first dose as soon as possible after suspected or confirmed exposure to myelosuppressive doses of radiation, and a second dose one week after. (drugs.com)

In a complementary analysis, 463 women with meningioma were observed among 123 997 already using cyproterone acetate in 2006 (risk of 383 per 100 000 person years in the group with the highest exposure in terms of cumulative dose). (bmj.com)
If DOL determines that the energy worker (1) had the potential for workplace radiation exposure and (2) had developed cancer, then the claim is forwarded to NIOSH for a dose reconstruction before DOL makes its final compensation decision. (cdc.gov)
DOL uses the results of the dose reconstruction to assist in determining the Probability of Causation (POC)-that is, the likelihood that the worker's cancer was caused by his/her workplace exposure to radiation. (cdc.gov)
When conducting a dose reconstruction, NIOSH may use personal radiation exposure data such as film badge readings, urine sample data, incident reports, medical x-rays, and employment history, as well as other information such as co-worker data, environmental exposure records, and process records. (cdc.gov)

75 g of oral dose is the recommendation of the WHO to be used in all adults, and is the main dosage used in the United States. (wikipedia.org)
Biosimilarity of UDENYCA has been demonstrated for the condition(s) of use (e.g. indication(s), dosing regimen(s), strength(s), dosage form(s), and route(s) of administration) described in its Full Prescribing Information. (drugs.com)
Since the calcium folinate rescue dosage regimen depends heavily on the posology and method of the intermediate- or high-dose methotrexate administration, the methotrexate protocol will dictate the dosage regimen of calcium folinate rescue. (janusinfo.se)

This interim guidance updates 2016 guidelines by recommending and providing implementation considerations for a novel 4-month daily treatment regimen, based on high-dose daily RPT with MOX, INH, and PZA ( 1 ) as a treatment option for U.S. patients aged ≥12 years with drug-susceptible pulmonary TB. (cdc.gov)

refer to the applied intermediate or high dose methotrexate protocol for posology and method of administration of calcium folinate. (janusinfo.se)

Direct evidence gap on fixed versus adjusted-dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: Systematic review and individual patient data meta-analysis. (bvsalud.org)

The present pilot study investigated whether modification of heparin dosing and/or early sheath removal would reduce the hemorrhagic complications associated with abciximab. (houstonmethodist.org)

To determine the comparative efficacy and safety of a fixed dose of benznidazole (BZN) with an adjusted- dose for Trypanosoma cruzi -seropositive adults without cardiomyopathy . (bvsalud.org)
Randomised controlled trials (RCTs) allocating participants to fixed or adjusted doses of BZN for T. cruzi-seropositive adults without cardiomyopathy were included. (bvsalud.org)
Children exposed to the same levels of ethylene glycol as adults may receive larger doses because they have greater lung surface area:body weight ratios and increased minute volumes:weight ratios. (cdc.gov)

In these cases, your doctor may want to change the dose, or other precautions may be necessary. (mayoclinic.org)

Rather than require the patient to calculate a percentage or to alter the actual glucose reading, the new method advises increasing or decreasing the insulin dose in units based on the patient's insulin sensitivity. (medscape.com)

Prescribers can now check the dose adjustments needed when prescribing diabetes combination medications in patients with kidney disease, using an updated MIMS quick-reference table. (mims.co.uk)
In this context, the information in this Table is intended primarily for prescribers, and patients should not adjust their medications without consulting their prescriber. (fda.gov)
The doses of your diabetes medications might need to be adjusted. (medicinenet.com)
Prior to the administration of medications, clinicians must know the level of sedation required for a given procedure and the appropriate dose of the pharmacologic agent or agents chosen. (medscape.com)

The trial confirmed that a 4-month daily treatment regimen containing high-dose RPT and MOX, as well as INH and PZA, is as effective as (noninferior to) the standard daily 6-month regimen in curing drug-susceptible TB ( 1 ). (cdc.gov)
We have recently developed and tested a "second generation" EPOCH regimen (EPOCH II) to replace stem cell transplant for lymphomas requiring high-dose intensity, including poor prognosis untreated aggressive lymphomas, potentially curable relapsed lymphomas, and low-grade lymphomas. (cancer.gov)
This regimen is based on experimental/clinical observations that suggest infusion schedules may improve the therapeutic index of natural product-derived cytotoxics, and that high-dose alkylator therapy can overcome drug resistance in lymphoma. (cancer.gov)

Objective To assess the risk of meningioma associated with use of high dose cyproterone acetate, a progestogen indicated for clinical hyperandrogenism. (bmj.com)
Findings from one 2022 clinical research trial noted that high doses of venlafaxine are associated with changes in different forms of plasticity in discrete brain areas. (drugwatch.com)

Conclusions A strong dose-effect relation was observed between use of cyproterone acetate and risk of intracranial meningiomas. (bmj.com)

The Endocrine Society has published new guidance for how to incorporate trend-arrow information from the Dexcom G5 continuous glucose monitoring (CGM) system into insulin dose adjustments for patients with diabetes. (medscape.com)
The CGM trend arrows give an understanding of which direction the glucose is going and the speed of the rise or fall, allowing one to make dose adjustments in anticipation of the rising or falling glucose level," she added. (medscape.com)
The new fine-tuning of dose adjustments takes into account what that glucose level is likely to be in the next half hour or so," Dr Laffel explained. (medscape.com)
Adjust insulin/pills when you eat more or less than recommended on your meal plan (your diabetes health care team can instruct you on making adjustments). (kidshealth.org)

Increase survival in patients acutely exposed to myelosuppressive doses of radiation (Hematopoietic Subsyndrome of Acute Radiation Syndrome). (drugs.com)

Diabetes medicines may need to be changed or adjusted - check with your diabetes health care team. (kidshealth.org)

Many variations of the GTT have been devised over the years for various purposes, with different standard doses of glucose, different routes of administration, different intervals and durations of sampling, and various substances measured in addition to blood glucose. (wikipedia.org)

Received prophylactic phenylephrine fixed dose infusion at 37.5 micrograms per minute. (aku.edu)
For pancreatic neuroendocrine tumours, Sunitinib Accord is given at a dose of 37.5 mg once a day without a rest period. (europa.eu)

The drug has been approved in European countries by national marketing authorisation procedures since the 1970s and is available on prescription under various trade names and dose strengths (1, 2, 10, 50, and 100 mg). (bmj.com)

Because there are no approved testosterone formulations for women anywhere in the world, clinicians typically use either formulations approved for men with doses adjusted for women, or compounded therapies. (medscape.com)
The consensus statement recommends that "male formulations can be used judiciously in small doses, with blood testosterone concentrations monitored regularly. (medscape.com)
However, it may not be possible to use [HA567 trade name] for some of the recommended doses and alternative formulations, such as oral solution, may be required. (who.int)

The guidance on metformin combination preparations reflects the recommended maximum daily metformin dose of 2g/day in patients with moderate renal impairment stage 3a (GFR 45-59ml/min) and 1g/day in patients with stage 3b (GFR 30-45ml/min). (mims.co.uk)

An approximate lethal concentration (ALC) of 10000 ppm at which a pulmonary oedema was observed is significantly greater than that of the repeated dose toxiciy test (i.e. (europa.eu)

Calcium folinate rescue is necessary when methotrexate is given at doses exceeding 500 mg/m2 body surface and should be considered with doses of 100 mg - 500 mg/m2 body surface. (janusinfo.se)
Prevention: Calcium folinate should be administered every day during treatment with trimetrexate and for 72 hours after the last dose of trimetrexate. (janusinfo.se)
Overdosage (possibly occurring with trimetrexate doses above 90 mg/m2 without concomitant administration of calcium folinate): after stopping trimetrexate, calcium folinate 40 mg/m2 IV every 6 hours for 3 days. (janusinfo.se)
In case of high dose pyrimethamine or prolonged treatment with low doses, calcium folinate 5 to 50 mg/day should be simultaneously administered, based on the results of the peripheral blood counts. (janusinfo.se)

People who are fully vaccinated with an additional or booster dose have a much lower risk of testing positive and dying from COVID-19, compared with those who are unvaccinated. (cdc.gov)
Then there is additional protection for those who are fully vaccinated and have also received a booster dose. (cdc.gov)

Adjust your medicines based on the diabetes health care team's instructions. (kidshealth.org)
If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. (mayoclinic.org)

Charts in the documents provide guidance on the amount of insulin to add to or subtract from the usual dose of insulin that would be given to cover carbohydrate intake or to correct an elevated glucose level. (medscape.com)
These new guidance documents simplify the approach to adjust for trend. (medscape.com)

Participants had at least one reimbursement for high dose cyproterone acetate and no history of meningioma or benign brain tumour, or long term disease status. (bmj.com)
Participants were considered to be exposed when they had received a cumulative dose of at least 3 g during the first six months (139 222 participants) and very slightly exposed (control group) when they had received a cumulative dose of less than 3 g (114 555 participants). (bmj.com)

The RORF/A for treatment interruption due to adverse events was 0.44 (95% CI 0.14-1.38), probably indicating no worse tolerance of fixed doses. (bvsalud.org)
The recommended dose for the treatment of hairy cell leukemia is 2 million IU/m2 administered intramuscularly or subcutaneously 3 times a week for up to 6 months. (centerwatch.com)
After several parenteral doses treatment can be switched over to the oral form. (janusinfo.se)

A full adult dose should not be given to a person weighing less than 42.6 kg (94 lb), or the excessive glucose may produce a false positive result. (wikipedia.org)

During both periods, VE after receipt of a third dose was or SARS-CoV-2 B.1.1.529 (Omicron) variant predominance. (cdc.gov)
however, the third dose of associated hospitalizations and ED/UC visits. (cdc.gov)

6 mg/0.6 mL in a single-dose prefilled syringe for manual use only. (drugs.com)
6 mg/0.6 mL in a single-dose prefilled autoinjector. (drugs.com)

Max dose to spinal cord was 49 Gy. (oncolink.org)

In the most commonly performed version of the test, an oral glucose tolerance test (OGTT), a standard dose of glucose is ingested by mouth and blood levels are checked two hours later. (wikipedia.org)
Since the 1970s, the World Health Organization and other organizations interested in diabetes agreed on a standard dose and duration. (wikipedia.org)

When drugs are used as adjuncts, decreasing the dose of each respective drug is important, so as to decrease the incidence of adverse effects. (medscape.com)

Glomerulonephritis: Evaluate and consider dose-reduction or interruption of UDENYCA if causality is likely. (drugs.com)

An AIDS-related lymphoma International Prognostic Index (IPI) has been developed and employs the age adjusted-IPI in addition to CD4 count, viral load, and prior history of AIDS. (medscape.com)
2 The management of primary mediastinal B-cell lymphoma (PMBCL) includes DA-REPOCH (dose-adjusted rituximab, etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin), which demonstrated superior outcomes (5-year overall survival rate was 97%) in the single arm phase 2 study from the national cancer institute obviating the need for radiation therapy (XRT). (silverchair.com)

Rates of bleeding and blood transfusion were reduced by low-dose heparin and early sheath removal and were lowest when both strategies were combined. (houstonmethodist.org)
If after 1 hour the blood glucose level is more than 7.8 mmol/L (140 mg/dL), it is followed by a 100 g glucose dose. (wikipedia.org)

Watch for these side effects if you are gradually decreasing your dose and after you stop taking the tablets. (medlineplus.gov)
You may need to increase your dose of tablets temporarily or start taking them again. (medlineplus.gov)
The required number of tablets should be dispersed in drinking water before administration of the dose. (who.int)

Under the Act, dose reconstruction is an accepted scientific method used by NIOSH to determine the amount of radiation a worker likely received while employed at a DOE facility or an Atomic Weapons Employer (AWE) facility. (cdc.gov)

Anatomy13

Organisms14

Diseases21

Chemicals and Drugs86

Analytical, Diagnostic and Therapeutic Techniques and Equipment91

Psychiatry and Psychology3

Phenomena and Processes37

Anthropology, Education, Sociology and Social Phenomena1

Information Science6

Named Groups1

Health Care34

Weight-adjusted8

Hepatic impairment2

Insulin doses4

Interactions2

Large doses3

Higher doses2

Adjustment8

Chemotherapy2

MRNA2

Vaccine3

Skip2

According to the patient's2

Toxicity3

Bolus1

Daily dose3

Second dose2

Exposure4

Dosage3

Considerations1

High-dose methotrexate1

Versus1

Modification1

Adults3

PRECAUTIONS1

Patient's1

Medications4

Regimen3

Clinical2

Risk of intracranial1

Adjustments4

Acutely1

Diabetes medicines1

Intervals1

37.52

Strengths1

Formulations3

Moderate renal1

Significantly1

Calcium4

Fully vaccinated2

Medicines2

Guidance2

Participants2

Treatment3

Adult1

Third dose2

Single dose2

Spinal cord1

Standard-dose2

Drug1

Reduction1

Lymphoma2

Blood2

Tablets3

Radiation1