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  • Differentiation
  • Adipose stem cells (ASCs) share many characteristics with BM-MSCs, including extensive proliferation and the ability to undergo multilineage differentiation [ 6 ] (like bone marrow MSCs, they can differentiate in vitro into adipogenic, osteogenic, chondrogenic, and myogenic cells when cultured in specific lineage-inducing culture media and into endothelial cells), and they display a noticeable plasticity both in vitro and in vivo . (hindawi.com)
  • The proliferation and differentiation of adipose stem cells can be regulated biochemically, as well as through the physical properties of microenvironments, such as the topography of the scaffolds, the "stiffness," and mechanical forces. (hindawi.com)
  • first reported the spontaneous differentiation of murine adipose-derived cells into cardiomyocytes in 2004 [ 1 ]. (hindawi.com)
  • In spite of its rather low rate (0.02% to 0.07%), the cardiomyogenic differentiation suggested that adipose tissue may provide a new source for cardiac progenitor/stem cells. (hindawi.com)
  • further demonstrated that the cardiac differentiation was far more efficient in brown adipose-derived cells ( 20%) than that described by Planat-Bénard [ 1 , 12 ]. (hindawi.com)
  • Stem
  • This second edition volume expands on the previous edition with a comprehensive update on recent developments in the Adipose Stromal/Stem Cells (ASC) field and the use of stroma vascular fraction (SVF) as a potential therapeutic strategy. (springer.com)
  • Cutting-edge and thorough, Adipose-Derived Stem Cells: Methods and Protocols, Second Edition is a valuable resource for anyone interested in learning more about the scientific advances in the field of ASC biology and application. (springer.com)
  • When compared to bone marrow mesenchymal stem cells (BM-MSCs), adipose tissue represents an ideal source for multipotent progenitors in adults [ 5 ]. (hindawi.com)
  • It is with honour that we acknowledge the participation of international investigators that have submitted original research and review articles to contribute to the evolving research field of adipose stem cell-biomaterial interactions and the development of clinically effective tissue engineering strategies. (hindawi.com)
  • The researchers used the new lab-on-a-chip to study how adult stem cells in adipose tissue develop into mature fat cells, conducting their investigations outside the body. (medindia.net)
  • Factors such as insulin and blood sugar levels influence whether or not adult stem cells in adipose tissue will develop into mature adipose cell. (medindia.net)
  • This enabled adipose-derived adult stem cells to be successfully converted into mature fat cells within the experiments, and the corresponding signalling pathway mTORC1 was also decoded. (medindia.net)
  • Stem cell researchers led by Dr Adam Reid, present a review of the current literature on the suitability of adipose-derived stem cells in peripheral nerve repair. (medindia.net)
  • Brown adipose was recently found to be a new source of cardiac stem cells, instrumental to myocardial regeneration. (hindawi.com)
  • In our study we have developed a new method for the efficient isolation of cardiac stem cells from brown adipose by combining different enzymes. (hindawi.com)
  • humans
  • In humans, adipose tissue is located: beneath the skin ( subcutaneous fat ), around internal organs ( visceral fat ), in bone marrow ( yellow bone marrow ), intermuscular ( Muscular system ) and in the breast tissue. (wikipedia.org)
  • A gene that is responsible for the development of harmful adipose tissue in humans, thereby raising the risk of insulin resistance and type 2 diabetes, has been identified. (medindia.net)
  • lipid
  • However, its main function is to be a reserve of lipids, which can be oxidised to meet the energy needs of the body and to protect it from excess glucose by storing triglycerides produced by the liver from sugars, although some evidence suggests that most lipid synthesis from carbohydrates occurs in the adipose tissue itself. (wikipedia.org)
  • The products can comprise a decellularized adipose extracellular tissue matrix and a reduced lipid content. (google.ca)
  • cells
  • The fat present in the cells of adipose tissue, composed mainly of varying mixtures of tripalmitin, tristearin, and triolein. (everything2.com)
  • In addition, it is now accepted that adipose cells present a broad plasticity that allows them to differentiate towards various mesodermal phenotypes. (hindawi.com)
  • Therefore, adipose-derived cells were also extensively investigated as candidates for the myocardial regeneration by many groups [ 16 , 17 ]. (hindawi.com)
  • adipose tissue Body fat-the cells that synthesize and store fat , releasing it for metabolism in fasting . (encyclopedia.com)
  • adipose tissue A body tissue comprising cells containing fat and oil. (encyclopedia.com)
  • Endocrinology
  • Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk," Journal of Clinical Endocrinology and Metabolism , vol. 88, no. 11, pp. 5163-5168, 2003. (hindawi.com)
  • marrow
  • Despite association with low bone density and skeletal fractures, marrow adipose tissue (MAT) remains poorly understood. (frontiersin.org)
  • Increased marrow adipose tissue (MAT) is associated with states of impaired bone formation ( 1 , 2 ) and dysfunctional hematopoiesis ( 3 - 5 ), although its physiological role remains unclear. (frontiersin.org)
  • Mice
  • To address this hypothesis, mice with specific deletion of adipose ABCA1 (ABCA1 −A/−A ) were generated, and significant reductions in plasma HDL-C (−15%) and apoA-I (−13%) levels were observed. (ahajournals.org)
  • functions
  • Although knowledge is still limited, current available literature suggests that the endocrine functions of adipose tissue might play an adaptive role during critical illness. (springer.com)
  • body
  • While many people have negative associations with deposits of adipose tissue on the body, people cannot thrive without it, although unusually high levels of this type of tissue have been linked with health problems. (wisegeek.com)
  • Although adipose tumors are common in most parts of the body, (1) they are extremely rare in the nasal cavity and paranasal sinuses. (thefreedictionary.com)