AdiponectinReceptors, AdiponectinLeptinInsulin ResistanceResistinObesityAdipose TissueAdipokinesIntercellular Signaling Peptides and ProteinsAMP-Activated Protein KinasesAdenylate KinaseAdipocytesInsulinDiabetes Mellitus, Type 23T3-L1 CellsBody Mass IndexBlood GlucosePPAR gammaBiological MarkersMetabolic Syndrome XReceptors, Cell SurfaceRNA, MessengerPolymorphism, Single NucleotideAdiposityGene Expression RegulationCase-Control StudiesSignal TransductionThiazolidinedionesTriglyceridesIntra-Abdominal FatFatty LiverCells, CulturedReverse Transcriptase Polymerase Chain ReactionPPAR alphaBody WeightLipidsSubcutaneous FatC-Reactive ProteinMice, Inbred C57BLTumor Necrosis Factor-alphaReceptors, LeptinInflammationMuscle, SkeletalMice, ObeseAtherosclerosisGene ExpressionGreeceGlucoseBlotting, WesternProteinsGlucose IntoleranceRisk FactorsMice, KnockoutEuropean Continental Ancestry GroupHypoglycemic AgentsDietary FatsLinear ModelsEnzyme-Linked Immunosorbent AssayGlucose Tolerance TestPhosphorylationMolecular WeightBody CompositionGenetic Association Studies