Adiponectin. Medical search. Frequent questions

Previous studies revealed the potential significance of circulating adiponectin levels with respect to the diagnosis and prediction of metabolic syndrome, but uncertainty has been noted across different cohorts. (frontiersin.org)
This study aims to compare the differences in circulating adiponectin levels and their relationships to regional adiposity , insulin resistance , serum lipid , and inflammatory factors in young, healthy Japanese women with different physical activity statuses. (bvsalud.org)

Circulating adiponectin concentrations increase during caloric restriction in animals and humans, such as in patients with anorexia nervosa. (wikipedia.org)
M. Matsubara, S. Maruoka and S. Katayose, "Inverse Relationship between Plasma Adiponectin and Leptin Concentrations in Normal-Weight and Obese Women," European Journal of Endocrinology, Vol. 147, No. 2, 2002, pp. 173-180. (scirp.org)
Enhanced platelet aggregation and activation markers are found in the metabolic syndrome associated to low adiponectin concentrations. (cun.es)
There was no correlation between plasma adiponectin concentrations and 24-hour RQ, (r = 0.09, p = 0.36) before or after adjustment for PFAT (r = 0.001, p = 0.99, respectively, partial correlation), and no correlation was found between plasma adiponectin concentrations and 24-hour EE (r = -0.12, p = 0.27). (monash.edu)
Discussion: Our cross-sectional data do not suggest physiological concentrations of fasting plasma adiponectin play a role in the regulation of whole-body fat oxidation or energy expenditure in resting conditions. (monash.edu)
Clone 399R is used to detect plasma adiponectin concentrations. (ximbio.com)
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. (ximbio.com)
Adiponectin concentrations are gender specific, with higher levels in females [ 2 ] [ 3 ] . (encyclopedia.pub)
Our results also highlighted age, truncal adiposity and dietary glycemic index as other determinants of serum adiponectin, however the extent to which these factors influence adiponectin concentrations may vary across ethnicities. (edu.au)

Adiponectin (also referred to as GBP-28, apM1, AdipoQ and Acrp30) is a protein hormone and adipokine, which is involved in regulating glucose levels and fatty acid breakdown. (wikipedia.org)
Adiponectin is an abundant serum adipokine composing up to 0.05% of total circulating protein [ 7 ]. (hindawi.com)
Adiponectin in an adipokine that is inversely associated with the fat mass, and has been linked to cardiometabolic risk stratification in the general population. (bepress.com)
Adiponectin (Adpn), an adipokine which displays insulin-sensitive properties, is a very promising target to tackle the cardiometabolic complications associated with Type 2 Diabetes (T2D). (anr.fr)
Adiponectin is a fat tissue-derived adipokine with beneficial effects against diabetes, cardiovascular diseases, and cancer. (phoenixpeptide.com)
Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is an 244 aminoacid protein, which is physiologically active, specifically and highly expressed in adipose cells (adipokine). (bertin-bioreagent.com)
Adiponectin is the adipokine associated with insulin sensitization, reducing liver gluconeogenesis, and increasing fatty acid oxidation and glucose uptake. (encyclopedia.pub)
Conclusions: Our findings suggest that molybdenum was associated with favorable profiles of HMW-adiponectin, leptin, and sOB-R. Exposures to cadmium , cesium, and lead were associated with adverse adipokine profiles. (cdc.gov)

Circulating adiponectin was determined by ELISA. (frontiersin.org)
This Rat Adiponectin ELISA Kit from Innovative Research is intended for quantitative detection of rat Adiponectin in cell culture supernates, serum, plasma (heparin, EDTA)and urine. (innov-research.com)
This rat Adiponectin ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. (innov-research.com)
The Human Adiponectin Elisa Kit Manufactured By Otsuka Pharmaceutical And Distributed By As One International reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (aabioetica.org)
Adiponectin Elisa Laboratories manufactures the adiponectin elisa mediagnost reagents distributed by Genprice. (synoviocytes.com)
The Adiponectin Elisa Mediagnost reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (synoviocytes.com)

Adiponectin (ADPQ), which is encoded by the AdipoQ gene located on chromosome 3q27.3, is a 244-amino acid pleiotropic hormone with a molecular weight of approximately 30 kDa for its basic subunit. (frontiersin.org)
Nous avons génotypé les deux polymorphismes mononucléotidiques du gène ADIPOQ chez 140 patients atteints de DNID sans lien de parenté et 66 témoins non diabétiques en recourant à l'analyse du polymorphisme de longueur des fragments de restriction par réaction en chaîne de polymérase. (who.int)
Adiponectin/ADIPOQ tissue specificity: Synthesized exclusively by adipocytes and secreted into plasma. (innov-research.com)
Interestingly, muscle expression of proteasomal genes correlated positively with SAT expression of ECM genes but inversely with the expression of ADIPOQ in SAT and plasma adiponectin. (sdu.dk)
There are several factors regulating the expression of adiponectin gene ( AdipoQ ), such as: forkhead box O1 (FOXO1), peroxisome proliferator-activated receptor γ (PPAR-γ), CCAAAT-enhancer binding protein α, and sterol regulatory element binding protein 1c (SREBP-1c) [ 9 ] . (encyclopedia.pub)

Adiponectin binds to a number of receptors. (wikipedia.org)
So far, two receptors have been identified with homology to G protein-coupled receptors, and one receptor similar to the cadherin family: Adiponectin receptor 1 (AdipoR1) Adiponectin receptor 2 (AdipoR2) T-cadherin - CDH13 These have distinct tissue specificities within the body and have different affinities to the various forms of adiponectin. (wikipedia.org)
Adiponectin receptors were demonstrated by western blotting. (cun.es)
Platelets express the receptors for adiponectin. (cun.es)
The adiponectin receptors, AdipoR1 and AdipoR2, are thought to transmit the insulin-sensitizing, anti-inflammatory, and atheroprotective effects of adiponectin. (diabetesjournals.org)
Activation of adiponectin receptors (AdipoRs) by its natural ligand, adiponectin has been known to be involved in modulating critical metabolic processes such as glucose metabolism and fatty acid oxidation as demonstrated by a number of in vitro and in vivo studies over last two decades. (phoenixpeptide.com)
There are three known receptors for adiponectin: adiponectin receptor 1 (AdipoR1), adiponectin receptor 2 (AdipoR2), and T-cadherin. (encyclopedia.pub)

In the development and progression of lung cancer, a pathogenic role of adiponectin was defined by both in vivo and in vitro studies [ 15 , 16 ]. (hindawi.com)
TAN, P.H. Evolving role of adiponectin in cancer controversies and update. (scielo.br)
MANTZOROS, C.S. The role of adiponectin in cancer: a review of current evidence. (scielo.br)
Conclusion: These new mechanistic and pathophysiology studies provide evidence for an important role of adiponectin in colon cancer. (nuthealth.org)

To evaluate the association of adiponectin and sCD40L levels with platelet aggregation in the MS and the effects of adiponectin on platelet aggregation and activation. (cun.es)
Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice. (nuthealth.org)
No previous studies have directly investigated the mechanistic effects of adiponectin on colon cancer in the settings of obesity, a high-fat diet and/or adiponectin deficiency. (nuthealth.org)
Objective: To investigate the effects of adiponectin on the growth of colorectal cancer in adiponectin-deficient or wild-type-C57BL/6 mice fed a low-fat or high-fat diet. (nuthealth.org)

Many studies have found adiponectin to be inversely correlated with body mass index in patient populations. (wikipedia.org)
Interestingly, only in the active group adiponectin levels were inversely correlated with forced expiratory volume (FEV) 1% decrease/year and FEV1% decrease. (hindawi.com)
High molecular weight adiponectin levels are inversely associated with adiposity in pediatric brain tumor survivors. (bepress.com)
In conclusion, HMW adiponectin is inversely correlated with adiposity in SCBT. (bepress.com)
Higher platelet aggregation was found in the MS. Adiponectin inversely correlated with P-selectin (R:-0.35, p:0.009), sCD40L (R:-0.24, p:0.05) and epinephrine and collageninduced aggregation (r=-0.80, p=0.005 and r=-0.70, p=0.011). (cun.es)
Adiponectin plasma levels and adipose-tissue gene expression were significantly lower in obese subjects and inversely correlated with obesity-associated variables, including high-sensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6). (diabetesjournals.org)
Paradoxically, adipose tissue-expressed adiponectin levels are inversely related to the degree of adiposity. (bertin-bioreagent.com)

Moreover, adiponectin levels negatively correlated with lipid profiles. (hindawi.com)
Previous studies revealed that adiponectin played a causal role in maintaining energy homeostasis via regulation of glucose and lipid metabolism. (frontiersin.org)
Considering the inconsistency of the few previous reports, the present study aimed to determine the levels of vitamin D, adiponectin, oxidative stress, lipid profile and nutrient intakes in females with acne. (magiran.com)
Blood samples were taken to determine the levels of 25-hydroxyvitamin D, adiponectin, malondialdehyde, total antioxidant capacity, and lipid profile. (magiran.com)
Expression system for standard: Adiponectin(ADPN) is a hormone secreted by adipocytes that regulates energy homeostasis and glucose and lipid metabolism. (innov-research.com)
Since its discovery, adiponectin has been identified as one of the key regulators involved in glucose and lipid metabolism. (encyclopedia.pub)
1, 2, 3 Moreover, human clinical trials have further supported these findings by demonstrating that InnoSlim® may enhance the adiponectin and AMPK signaling pathway in tested subjects, leading to potential improvements in blood sugar and lipid levels. (nulivscience.com)
Adipokines ( adiponectin and leptin ), full serum lipid , and inflammatory factors [ white blood cell counts, C-reactive protein , tumor necrosis factor -α, tissue plasminogen activator inhibitor-1 ( PAI-1 )] were measured in 101 sedentary and 100 endurance-trained healthy Japanese women ( aged 18-23 years). (bvsalud.org)
Furthermore, LFM was associated with a favorable lipid profile against cardiovascular diseases (CVDs) in the whole study cohort, but this association became insignificant when adiponectin was taken into account. (bvsalud.org)
The associations among adiponectin , lipid , and inflammatory factors are likely different in women with different physical activity statuses. (bvsalud.org)
The correlation of LFM and a favorable lipid profile against CVD and adiponectin is likely involved in this association . (bvsalud.org)

In conclusion, PIO treatment in type 2 diabetes causes a 3-fold increase in plasma adiponectin concentration. (nih.gov)
The increase in plasma adiponectin is strongly associated with a decrease in hepatic fat content and improvements in hepatic and peripheral insulin sensitivity. (nih.gov)
The increase in plasma adiponectin concentration after thiazolidinedione therapy may play an important role in reversing the abnormality in hepatic fat mobilization and the hepatic/muscle insulin resistance in patients with type 2 diabetes. (nih.gov)

adiponectin oligomeric profiles were analysed by western blot. (hindawi.com)
In the circulation, Adiponectin is present as three different oligomeric complexes, including the high molecular weight (HMW), the middle molecular weight (MMW, also called hexamer) and low molecular weigh (MMW, also called trimer) forms 8. (prospecbio.com)
Different oligomeric complex of Adiponectin activates different signaling pathways and exerts distinct functions. (prospecbio.com)
Antibody recognizes both monomeric and trimeric adiponectin, oligomeric forms not tested. (medixbiochemica.com)
Oligomeric states of adiponectin appear to determine its biological activity. (phoenixpeptide.com)

After its secretion by adipocytes, adiponectin oligomerizes in three forms: trimers of low molecular weight (LMW), hexamers of medium molecular weight (MMW), and multimers of high molecular weight (HMW) [ 8 ]. (hindawi.com)

Adiponectin is a 244-amino-acid-long polypeptide (protein). (wikipedia.org)
Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation. (wikipedia.org)
Adiponectin is secreted into the bloodstream, where it accounts for about 0.01% of all plasma protein at around 5-10 μg/mL. (wikipedia.org)
These improvements in patients' conditions are associated with immunometabolic processes involving adiponectin, leptin, and C-reactive protein. (hindawi.com)
However, rosiglitazone significantly increased adiponectin protein expression in WAT, suggesting that WAT contributes to hyperadiponectinemia in this context. (frontiersin.org)
Adiponectin is an adipose tissue-secreted protein and is a multifunctional adipocytokine. (aspetjournals.org)
Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition. (ximbio.com)
The last few years have brought a rising body of evidence that adiponectin is a multipotential protein with anti-inflammatory, metabolic, anti-atherogenic, and reactive oxygen species (ROS) protective actions. (encyclopedia.pub)
Human adiponectin protein has 244 amino acids (30 kDa), as well as the complex primary structure of a signal peptide, a hyper-variable region, a collagenous domain of 22 G-X-Y repeats, and a globular domain. (encyclopedia.pub)
Adiponectin is an adipocyte-derived protein with anti-diabetic, anti-atherogenic and anti-inflammatory action, but there are few studies on its association with cardiovascular and metabolic risk factors in different ethnic groups in Australia. (edu.au)

Adiponectin in combination with leptin has been shown to completely reverse insulin resistance in mice. (wikipedia.org)
Heterogeneity analysis revealed that an increasing index of insulin resistance was independently associated with improving the performance of adiponectin upon metabolic syndrome diagnosis (ratio of diagnostic odds ratio = 3.89, 95% CI: 1.13-13.9). (frontiersin.org)
Low plasma levels of the anti-inflammatory factor adiponectin characterize obesity and insulin resistance. (diabetesjournals.org)
A reduction in adiponectin serum levels is accompanied by insulin resistance states, such as obesity and type II diabetes mellitus. (bertin-bioreagent.com)

High-molecular-weight adiponectin was further found to be associated with a lower risk of diabetes with similar magnitude of association as total adiponectin. (wikipedia.org)
However, coronary artery disease has been found to be positively associated with high molecular weight adiponectin, but not with low molecular weight adiponectin. (wikipedia.org)
We tested the hypothesis that high molecular weight (HMW) adiponectin levels, the more biologically active form of adiponectin, were associated with adiposity in SCBT similarly to non-cancer controls. (bepress.com)
Acute effects of acylated and unacylated ghrelin on total and high molecular weight adiponectin inmorbidly obese subjects. (ximbio.com)
The circulating concentration and ratio of total and high molecular weight adiponectin in post-menopausal women with and without osteoporosis and its association with body mass index and biochemical markers of bone metabolism. (ximbio.com)
Serum adipokines including high molecular weight (HMW)-adiponectin, leptin, and soluble leptin receptor (sOB-R) were measured at the follow-up visit (2002-2003). (cdc.gov)

Anti Mouse Adiponectin receptor 2 100 µl is available at Genprice in USA and Gentaur in Europe. (genprice.shop)

By increasing adiponectin levels and secretion in fat cells, InnoSlim® works to stimulate the phosphorylation and activation of AMPK in skeletal muscles. (nulivscience.com)

Objective: We investigated whether lifestyle intervention during pregnancy modifies pregnancy leptin and adiponectin levels, adipokines and their association with body mass index (BMI). (scirp.org)

0.05), whereas the inverse correlation between adiponectin plasma levels or adiponectin gene expression in adipose tissue with plasma IL-6 were largely dependent on the clustering of obesity-associated variables. (diabetesjournals.org)

Conclusions: Leptin and adiponectin are critical for glucose homeostasis and there are distinct genetic differences for these two hormones between diabetic and non-diabetic morbidly obese patients. (sages.org)
L. Hilakivi-Clarke, S. Assis, J. Raitanen and R. Luoto, "Effects of Dietary and Physical Activity Intervention during Pregnancy on Circulating Leptin and Adiponectin Levels," Food and Nutrition Sciences , Vol. 3 No. 4, 2012, pp. 556-567. (scirp.org)
BEVILACQUA, F. The potential role of leptin and adiponectin in obesity: a comparative review. (scielo.br)

However, the association of adiponectin with bladder contraction has not been investigated. (aspetjournals.org)

In non-obesity-related inflammatory disorders, adiponectin levels are increased [ 9 - 11 ]. (hindawi.com)
Adiponectin may serve as a biomarker of cardiometabolic risk and response to interventions to prevent and manage obesity and its comorbidities in SCBT. (bepress.com)
Low adiponectin levels may play an important role in the development of colon and other obesity-related malignancies. (nuthealth.org)
Adiponectin plays an important role in pathogenesis and amplification of insulin-resistant states in humans, where levels are reduced in patients with type-2 diabetes and obesity. (ximbio.com)

Hazell, M.J. (2009) Development and Clinical Applications of Immunoassays for Human Adiponectin. (ximbio.com)

In conclusion, individuals with Iranian or Indian ancestries may have lower adiponectin levels compared to Europeans. (edu.au)

Adiponectin is secreted from adipose tissue (and also from the placenta in pregnancy) into the bloodstream and is very abundant in plasma relative to many hormones. (wikipedia.org)

Systematic evaluation was performed for diagnostic accuracy and predictivity of adiponectin variation for metabolic syndrome in enrolled studies including 1,248 and 6,020 subjects, respectively. (frontiersin.org)
Adiponectin can identify metabolic syndrome with moderate accuracy (area under the curve = 0.81, 95% CI: 0.77-0.84). (frontiersin.org)
In addition, reductions in adiponectin were associated with increasing metabolic syndrome incidence in a linear dose-response manner. (frontiersin.org)
In conclusion, adiponectin measurement might have potential benefits in the detection of metabolic syndrome. (frontiersin.org)
In vitro, it was found that adiponectin directly controls malignant potential (cell proliferation, adhesion, invasion and colony formation) and regulates metabolic (AMPK/S6), inflammatory (STAT3/VEGF) and cell cycle (p21/p27/p53/cyclins) signalling pathways in both mouse MCA38 and human HT29, HCT116 and LoVo colon cancer cell lines in a LKB1-dependent way. (nuthealth.org)
ABSTRACT This study aimed to estimate the frequency of the SNPs (+45T>G and +276G>T) genotypes and investigate the association between the two SNPs and adiponectin concentration, metabolic parameters and risk of T2DM in the Bahraini population. (who.int)

Partial correlations and multivariable regression analyses assessed the relationship between HMW adiponectin and adiposity. (bepress.com)
Relationships of adiponectin to regional adiposity, insulin sensitivity, serum lipids, and inflammatory markers in sedentary and endurance-trained Japanese young women. (bvsalud.org)
These findings suggest that adiponectin is primarily associated with regional adiposity and HDL-C regardless of insulin sensitivity and physical activity status in young, healthy women . (bvsalud.org)

This study attempts to identify differences in gene expression in diabetic and non-diabetic patients undergoing bariatric surgery with regards to adiponectin and leptin. (sages.org)
To elucidate the relationship between plasma levels of adiponectin, adiponectin gene expression in adipose tissue, and markers of inflammation, we obtained blood samples, anthropometric measures, and subcutaneous adipose tissue samples from 65 postmenopausal healthy women. (diabetesjournals.org)
Similar to adiponectin, ADP-1 increased the expression of the adiponectin receptor 1 gene. (phoenixpeptide.com)

Adiponectin levels were significantly higher while leptin levels were lower in patients with CF than in healthy controls. (hindawi.com)
On the 60th day, serum adiponectin was significantly lower in cholesterol, Spirulina and cholesterol + Spirulina groups than in control and oil + cholesterol groups. (vin.com)
The feeding with cholesterol and/or Spirulina significantly lowered the serum adiponectin levels. (vin.com)

Adiponectin exerts some of its weight-reduction effects via the brain. (wikipedia.org)
Adipose tissue, through adiponectin and leptin, exerts several effects on energy metabolism and inflammatory processes. (hindawi.com)

HFC (magnetic resonance spectroscopy) and basal plasma adiponectin concentration were quantitated before and after PIO (45 mg/d) for 16 wk. (nih.gov)

Adiponectin is a hormone exclusively expressed from adipose tissue. (prospecbio.com)
Bone marrow adipose tissue (MAT) contributes to increased circulating adiponectin, an insulin-sensitizing hormone, during caloric restriction (CR), but whether this occurs in other contexts remains unknown. (frontiersin.org)
Whether administration of adiponectin to individuals with low levels of this hormone will increase their fat oxidation rates/energy expenditure remains to be established. (monash.edu)
One of the major ways is by secreting a hormone called Adiponectin. (fivejourneys.com)

Adiponectin functions by controlling the cellular energy metabolism through the regulation of the AMPK signaling pathway. (nulivscience.com)

In conclusion, adiponectin is associated with bladder smooth muscle contraction, which involves an increase in Ca 2+ dependency of contraction mediated by PKC α expression. (aspetjournals.org)
In conclusion, our data suggest a transcriptional mechanism leading to decreased adiponectin plasma levels in obese women and demonstrate that low levels of adiponectin are associated with higher levels of hs-CRP and IL-6, two inflammatory mediators and markers of increased cardiovascular risk. (diabetesjournals.org)

In addition, data from in vitro studies on lung cells were consistent with an anti-inflammatory function of adiponectin [ 11 , 12 ], and adiponectin-deficient mouse models develop lung function impairment and systemic inflammation [ 13 , 14 ]. (hindawi.com)
Many studies demonstrate that Adiponectin has direct anti-diabetic, anti-atherogenic and anti-inflammatory functions. (prospecbio.com)
Under normal circumstances adiponectin presents anti-inflammatory, pro-apoptotic and anti-proliferative effects (Booth et al . (scielo.br)

Transgenic mice with increased adiponectin show reduced adipocyte differentiation and increased energy expenditure associated with mitochondrial uncoupling. (wikipedia.org)

Objective: To test the hypothesis that low adiponectin is associated with low fat oxidation in humans. (monash.edu)

Initially, three adiponectin molecules bind together to form a homotrimer. (wikipedia.org)
Accordingly, adiponectin-mimetic molecules possess significant pharmacological potential. (phoenixpeptide.com)

Adiponectin has been shown to increase insulin sensitivity and decrease plasma glucose by increasing tissue fat oxidation. (bertin-bioreagent.com)
The cumulative loss of fat leads to a decrease in adipose-derived adiponectin and leptin. (medscape.com)

Plasma levels of adiponectin are lower in obese subjects than in lean subjects. (wikipedia.org)

Trimeric form of Adiponectin Human trimeric form was expressed in HEK293 cells. (prospecbio.com)

A monoclonal antibody from mouse specific for Adiponectin has been precoated onto 96-well plates. (innov-research.com)
Standards(E.coli, I19-N244) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for Adiponectin is added subsequently and then followed by washing with PBS or TBS buffer. (innov-research.com)

In view of the absence of reports regarding adiponectin levels in dogs and the occurrence of malignant neoplasms, the present study aimed to compare the serum levels of adiponectin in clinically normal bitches and in those with a diagnosis of mammary carcinoma. (scielo.br)

Patients with T2D were more insulin resistant and had lower plasma adiponectin than obese controls. (sdu.dk)

Decreased levels of adiponectin are linked to difficulties in regulating blood sugar and breaking down fatty acids. (nulivscience.com)
When adiponectin levels increase, there is a subsequent rise in AMPK phosphorylation, which promotes the breakdown of fatty acids. (nulivscience.com)

Adiponectin connects energy balance regulation in the central nervous system and peripheral tissues [ 10 ] . (encyclopedia.pub)

Potentially, pre- and post-operative changes in adiponectin and leptin expression are involved in this process. (sages.org)
The antidiabetic thiazolidinediones (TZDs) also promote MAT expansion and hyperadiponectinemia, even without increasing adiponectin expression in white adipose tissue (WAT). (frontiersin.org)
Notably, this was also the only group in which tibial adiponectin expression was lower than in WT mice, suggesting a close association between MAT adiponectin production and circulating adiponectin. (frontiersin.org)
Adiponectin treatment also suppressed angiogenesis assessed by CD31 staining and VEGFb and VEGFd mRNA expression in tumours obtained from mice fed a high-fat diet and from adiponectin-deficient mice. (nuthealth.org)
qRT-PCR confirmed most of these findings and showed lower expression of adiponectin in SAT and higher expression of myostatin in muscle in T2D. (sdu.dk)

Anatomy7

Organisms2

Diseases7

Chemicals and Drugs20

Analytical, Diagnostic and Therapeutic Techniques and Equipment10

Phenomena and Processes9

Health Care3

Circulating adiponectin levels2

Concentrations9

Adipokine8

ELISA6

AdipoQ5

Receptors7

Role of adiponectin4

Effects of adiponectin4

Inversely7

Lipid11

Increase in plasma adiponectin3

Oligomeric5

Adipocytes1

Protein10

Insulin resistance4

Molecular weight6

Anti-Mouse Adiponectin1

Secretion1

Adipokines1

0.051

Leptin and adiponectin3

Association of adiponectin1

Obesity4

Human adiponectin1

Lower adiponectin1

Secreted from adipose tissue1

Metabolic6

Adiposity3

Gene3

Significantly3

Exerts2

Concentration1

Hormone4

Energy metabolism1

Conclusion2

Inflammatory3

Adipocyte1

Test the hypothesis1

Molecules2

Decrease2

Obese subjects1

Trimeric1

Antibody2

Serum levels1

Plasma1

Fatty Acids2

Regulation1

Expression5