Adherence resistance. Medical search. Frequent questions

Background: Antimicrobial resistance among pathogens, especially. (the-hospitalist.org)
Biofilms may also enhance the development of antimicrobial resistance - a gradual decrease in antimicrobial concentration means that some bacteria could be exposed to a mutant selection window. (vin.com)
Antimicrobial resistance (AMR) is the ability of miroorganisms (including bacteria, fungi, viruses, etc.) to nullify the effects of antimicrobial drugs, resulting in these drugs becoming ineffective. (bd.com)
Overall adherence to hand hygiene standards in the operating room sat at just 8.1 percent, according to a study recently published in Antimicrobial Resistance & Infection Control . (beckershospitalreview.com)
1 Antimicrobial resistance happens when bacteria or fungi develop the ability to defeat the drugs designed to kill them. (cdc.gov)
CDC works closely with partners from state and local health departments, academia, international organizations, and other federal agencies to address issues surrounding antimicrobial resistance. (cdc.gov)

To better understand the impact of reduced adherence and inform strategies for improving the effectiveness of primaquine radical cure regimens, an individual patient data pooled meta-analysis of prospective P. vivax clinical efficacy studies was undertaken to investigate the effect of reduced adherence on the risk of P. vivax recurrence between days 7 and 90 and the key patient factors that contribute to reduced adherence. (biomedcentral.com)
The only large randomised trial to date of second-line ART in African adults found that those receiving NRTI-based second-line regimens had equivalent virological suppression to those receiving regimens based on 2 new drug classes [ 7 ], suggesting that NRTI cross-resistance may have less relevance than feared. (prolekare.cz)
We therefore investigated virological outcomes and resistance in the ARROW randomised trial (ISRCTN24791884), which compared first-line ART regimens and CD4 monitoring strategies in children and adolescents in Uganda and Zimbabwe [ 8 ]. (prolekare.cz)
Researchers and pharmacists have helped by offering simplified treatment regimens that lead to better long term medication adherence, improve quality of life, avoid long term toxicities, and reduce risk of virologic failure. (theseoultimes.com)
Although all participants had used - and a majority had developed resistance to - at least two antiretroviral drug classes, they were able to construct viable regimens using a ritonavir-boosted protease inhibitor and an active third agent such as etravirine ( Intelence ), maraviroc ( Celsentri or Selzentry ) or a nucleoside/nucleotide reverse transcriptase inhibitor. (aidsmap.com)
Select and optimize HIV treatment regimens based on clinical safety and efficacy, propensity for resistance, and patient characteristics. (thedoctorschannel.com)
Consider patient preferences when selecting HIV treatment regimens to increase adherence and compliance to therapy. (thedoctorschannel.com)
Healthcare providers can help improve medication adherence by educating patients about their medications, simplifying medication regimens, and addressing any concerns or barriers to adherence that patients may have. (revenuexl.com)

Likewise non-adherence to antiretroviral therapy (ART) in treatment of HIV is common to all groups of individuals on treatment and is comparable to that in other chronic diseases like diabetes, hypertension and heart disease. (theseoultimes.com)
Association between adherence to antiretroviral therapy and human immunodeficiency virus drug resistance. (bvsalud.org)

Long-acting injectable antiretroviral treatment can improve medication adherence in patients who struggle with regularly taking daily pills, according to research presented at the Association of Nurses in AIDS Care 2023 Annual Meeting. (medscape.com)
Dr. Gibson Clinical question: Is there an association between chronic medication adherence and emergency department (ED) visits and hospitalizations? (the-hospitalist.org)
Background: Medication adherence for. (the-hospitalist.org)
At the recently concluded 6th National Conference of AIDS Society of India (ASICON 2013), Dr K Satish, a senior Pulmonologist from Bangalore, stressed upon the importance of adherence to both care and medication for the success of any treatment programme including HIV/AIDS. (theseoultimes.com)
What is Medication Adherence and Why is it Important? (revenuexl.com)
Why has Medication Adherence become important in recent times? (revenuexl.com)
According to the World Health Organization, medication adherence can have a more direct impact on patient outcomes than the specific treatment itself. (revenuexl.com)
Medication adherence can affect quality and length of life, health outcomes, and overall healthcare costs. (revenuexl.com)
The growing availability of technology solutions to improve medication adherence, including reminders, tracking tools, e-prescribing, and telemedicine, has made it easier to monitor and support patients in taking their medications as prescribed. (revenuexl.com)
These factors have combined to make medication adherence an increasingly important area of focus for healthcare providers, patients, payers, and policymakers. (revenuexl.com)
What is Medication Adherence? (revenuexl.com)
Medication adherence refers to the extent to which a patient takes their medications as prescribed by their healthcare provider. (revenuexl.com)
It is important for achieving the intended therapeutic benefit of the medication, as well as for avoiding potentially harmful side effects and minimizing the risk of drug resistance. (revenuexl.com)
Non-adherence to medication is a common problem and can lead to reduced treatment effectiveness, disease progression, and increased healthcare costs. (revenuexl.com)
There are many reasons why patients may struggle with medication adherence, including forgetfulness, difficulty with the medication regimen, side effects, and concerns about cost. (revenuexl.com)
These are some of the top challenges to ensuring medication adherence, but there can be many other factors that contribute to non-adherence, such as social and behavioral factors, environmental factors, and the complexity of the healthcare system. (revenuexl.com)
Medication adherence is important because it directly affects the effectiveness of a patient's treatment plan. (revenuexl.com)
Poor medication adherence can result in increased healthcare utilization and higher costs, as patients may require more frequent hospitalizations, emergency room visits, or other treatments. (revenuexl.com)

Clinicians should address modifiable barriers to adherence and engagement in care to help ensure optimal virologic suppression. (hivguidelines.org)
Two main barriers to treatment are resistance to the drug and adherence to a therapy schedule," notes Walmsley. (sciencedaily.com)

Our hypothesis is that increased nasal resistance due to nasal inflammation predisposes to OSA in this population. (cdc.gov)
Does increase in nasal resistance due to nasal inflammation play a role in the development of OSA in those responders who have chronic rhinosinusitis? (cdc.gov)

Resistance to both INH and RIF substantially increases the cost and duration of treatment, while decreasing the efficacy. (cdc.gov)
It also reviews the way drug resistance develops and spreads, methods used to assess the presence and level of drug resistance, and the extent to which chloroquine and sulfadoxine/pyrimethamine (SP)-the two most widely used antimalarial drugs in the world today-have now lost efficacy. (nationalacademies.org)
Continuous Positive Airway Pressure (CPAP) is the standard therapy for OSA but despite its efficacy has poor adherence. (cdc.gov)
Although management without VL monitoring has enabled ART rollout, children with virological failure risk developing resistance, which may reduce efficacy of second-line therapy. (prolekare.cz)
Lower efficacy for protease inhibitors was not due to lower adherence to treatment. (lu.se)
The sole approved drug in this class, raltegravir, has demonstrated long-term efficacy and minimal toxicity, though it has a relatively low barrier to resistance. (aidsmap.com)

These challenges can lead to poor adherence, increased viral loads, and drug resistance, they explain. (medscape.com)
Patients who are monitored at longer intervals should be carefully selected based on length of viral suppression, CD4 count, use of ART for transmission prevention, and adherence to medical care, including visit attendance and retention in care. (hivguidelines.org)
Causes of viral rebound can include drug resistance, poor adherence to an HIV treatment regimen or interrupting treatment. (aidsmap.com)

We report findings from an intervention study using telehealth modalities to determine whether provision of telehealth services can improve access to care and increase adherence to cognitive therapy in veterans with mild traumatic brain injury (TBI) while matching traditional care in terms of outcomes. (medscimonit.com)
Here we explored factors associated with adherence to exercise within the setting of a 24-week exercise intervention. (natap.org)
Sedentary adults (50-75 years) with or without HIV enrolled in a 24-week supervised endurance/resistance exercise intervention. (natap.org)
Adherence to the intervention was calculated as the number of attended exercise sessions divided by the number of expected exercise sessions. (natap.org)
Overall, 18 of the 42 trials reported that the studied intervention improved adherence to exercise or physical activity. (racgp.org.au)

Cite this: Long-Acting Antiretrovirals for HIV Improve Adherence - Medscape - Oct 30, 2023. (medscape.com)

Regimen simplification advances patient care by way of better adherence, lower resistance development, higher persistency leading to long term success, less hospitalization and lower cost of care. (theseoultimes.com)

In an analysis based on the ARROW trial, Alex Szubert and colleagues report on virological and drug resistance outcomes in children with HIV infection. (prolekare.cz)
But we need more than 90% adherence for successful outcomes of HIV treatment. (theseoultimes.com)
By improving adherence, healthcare providers can reduce the cost of care and improve patient outcomes. (revenuexl.com)
There has been a growing recognition of the negative impact of non-adherence to medications on patient outcomes, including increased hospitalizations, higher rates of morbidity and mortality, and higher healthcare costs. (revenuexl.com)
By improving adherence, healthcare providers can help ensure that patients receive the full benefit of their medications and achieve better health outcomes. (revenuexl.com)

Adherence to these recommendations will help prevent the occurrence of more cases of drug-resistant TB, reduce the occurrence of treatment failure, and reduce the transmission of TB in the United States. (cdc.gov)
However, they readily acquire multi-drug resistance (see below). (vin.com)
We also found that patients did not develop resistance to the drug, a major factor in HIV treatment. (sciencedaily.com)
If patients do not take their drugs right on schedule - for example, three pills three times a day every eight hours - the drug level could decrease, thereby allowing the virus to grow and resistance to the drug could occur. (sciencedaily.com)
In addition to greater potency, no patients with virologic failure on the lopinavir-ritonavir combination showed evidence of resistance to the drug compared to the nelfinavir group, in which 33 per cent of failing patients developed resistance. (sciencedaily.com)
Adherence lowers the risk for drug resistance. (treatmentactiongroup.org)
What is drug resistance? (treatmentactiongroup.org)
Some people have drug resistance even though they have never been on hepatitis C treatment-but many can be cured anyway. (treatmentactiongroup.org)
If drug levels get too low, a drug can stop working, putting people at risk for drug resistance or not being cured. (treatmentactiongroup.org)
Suboptimal adherence predisposes to drug resistance. (theseoultimes.com)
As a result of drug resistance, infections become harder to treat, increasing the risk of disease spread, severe illness and death. (bd.com)
An increase of transmitted drug resistance was observed in the InfCareHIV cohort. (lu.se)
The investigational HIV integrase inhibitor elvitegravir taken once daily continued to perform as well as twice-daily raltegravir ( Isentress ) at 96 weeks for treatment-experienced people with extensive drug resistance, according to data presented last week at the 19th International AIDS Conference in Washington, DC. (aidsmap.com)

No virulence factors were detected for any strain and only the non-transferable erm(49) gene, which confers resistance to erythromycin and clindamycin, was identified in the genome of B. longum KABP042. (frontiersin.org)
Some strains produce a protein that confers resistance to complement by interfering with the formation of the membrane attack complex. (medscape.com)

In the past decades, hospitals around the world have reported endoscopic transmission outbreaks of multidrug resistance and water-borne organisms [ 6 - 8 ]. (hindawi.com)

The chronic inflammation makes each bout of infection harder to treat and repeated antimicrobial use may select for resistance. (vin.com)
Our aim is to place the findings of recent Cochrane musculoskeletal reviews in a context immediately relevant to general practi-tioners (GPs) by summarising the findings of a review of interventions to improve adherence to exercise for adults with chronic musculoskeletal pain (CMP). (racgp.org.au)
This review assessed the effectiveness of different interventions to improve adherence to exercise therapy in people with chronic musculoskeletal pain. (racgp.org.au)
In WTC responders we hypothesized that chronic rhinosinusitis (CRS) would be associated with increased prevalence and severity of obstructive sleep apnea (OSA), mediated by elevated total nasal resistance (TNR). (cdc.gov)

3M™ EMI Shielding Tape 1181 has a deadsoft, copper foil backing with a pressure sensitive, electrically conductive, acrylic adhesive that ensures firm adherence. (3m.com)

He defined adherence as the patient s active participation in planning care and treatment and is based upon shared decision making between patient and provider. (theseoultimes.com)

DISCUSSION: This is the first multicenter trial designed to test the hypothesis that adherence to CPAP therapy relates to nasal resistance and CPAPFlex will improve adherence to CPAP in those subjects with high nasal resistance. (cdc.gov)
12,13 Therefore, interventions that improve adherence to exercise and physical activity are extremely important for optimising the clinical benefits of these interventions for people with CMP. (racgp.org.au)
This paper summarises the findings from a systematic review by Jordan et al 14 of randomised controlled trials (RCTs) or quasi-RCTs, which assessed the effectiveness of different interventions to improve adherence to exercise therapy in people with CMP. (racgp.org.au)
Interventions to improve adherence varied widely between trials, which differed in the types of exercise therapy, methods of delivery, exercise adherence-enhancing strategies, self-management programs and cognitive and/or behavioural therapy. (racgp.org.au)
Will CPAP adherence be affected by high nasal resistance in those with OSA and will reducing expiratory pressure using CPAP flex improve adherence? (cdc.gov)

When adherence was quantified by total mg/kg dose received among 3706 patients, 347 (9.4%) had poor adherence, 88 (2.4%) had moderate adherence, and 3271 (88.2%) had complete adherence to treatment. (biomedcentral.com)
In some cases, it may make sense for you to change your treatment to a treatment with a lower risk of resistance. (aidsmap.com)
This will lead to treatment failure and resistance. (vin.com)
The likely sensitivity of Malassezia and staphylococci can be predicted using knowledge of local resistance patterns and previous treatment. (vin.com)
The most important thing a person can do to be cured is not to miss taking doses of HCV treatment-called adherence . (treatmentactiongroup.org)
But resistance to other drugs can last for years and might prevent re-treatment from working. (treatmentactiongroup.org)
Antibiotic resistance in the body increases if the dose is arbitrarily reduced or stopped prior to treatment completion. (nursingcenter.com)
The present study contributes to understanding the relationship of nasal /upper airway mechanisms to the development of sleep apnea in this population and explores the possibility of improving comfort and adherence to CPAP treatment by modifying how CPAP is delivered. (cdc.gov)
Determining the comparative effectiveness of CPAP versus CPAPflex in those subjects with OSA who have high nasal resistance through increasing adherence to therapy, thus allowing the WTC Health Program to make appropriate treatment decision with regard to these responders. (cdc.gov)
Skipping doses or not taking medications for the full duration as prescribed can increase the risk of complications and lead to resistance to treatment. (revenuexl.com)

Addressing Antibiotic Resistance in Dentistry: "What can WE do? (cdc.gov)
Antibiotic resistance and antibiotic-associated adverse events are now some of our most serious global health threats (1). (cdc.gov)
Misuse and overuse of antibiotics have contributed to antibiotic resistance (1). (cdc.gov)
Combatting antibiotic resistance is not a one-time event. (cdc.gov)
Making health care safer: protect patients from antibiotic resistance. (ahrq.gov)

For adherence assessed by percentage of supervised primaquine, 2790 patients (40.3%) had poor adherence (≤ 50%) and 4127 (59.7%) had complete adherence. (biomedcentral.com)
8-11 However, poor adherence to exercise and physical activity has been shown to compromise their effectiveness in usual care. (racgp.org.au)
Dr Satish said that, Adherence is a complicated issue regardless of the nature of the disease and is equally problematic in resource- poor and rich settings. (theseoultimes.com)
Then again association between poor-adherence and ARV resistance is well documented. (theseoultimes.com)

Adherence to primaquine was inferred from i) the percentage of supervised doses and ii) the total mg/kg dose received compared to the target total mg/kg dose per protocol. (biomedcentral.com)
Medications that require multiple doses, frequent adjustments, or specialized administration can be difficult for patients to follow and can lead to confusion and non-adherence. (revenuexl.com)

The conductive particles in the adhesive offer low resistance between the substrate and the backing. (3m.com)

Imperfect adherence is a major barrier to effective primaquine radical cure of Plasmodium vivax . (biomedcentral.com)
The cost of medications can be a barrier to adherence, especially for patients who are uninsured or under-insured. (revenuexl.com)

Subjects with high nasal resistance may have greater difficulty in tolerating this therapy than those who do not have high nasal resistance. (cdc.gov)
In 400 subjects with OSA we will perform a randomized double blind cross-over study comparing CPAP to CPAPflex, and relate nasal resistance to adherence to CPAP therapy. (cdc.gov)
Increased nasal resistance is associated with decreased adherence to CPAP therapy. (cdc.gov)
2. Use of CPAPFlex improves adherence with CPAP therapy in subjects with high nasal resistance, but not in those with low nasal resistance. (cdc.gov)
3. The benefit of CPAPFlex on adherence is greatest when offered at CPAP therapy initiation rather than as a "rescue" therapy in subjects with high nasal resistance. (cdc.gov)
How does hostile resistance interfere with the benefits of cognitive-behavioral therapy for panic disorder? (bvsalud.org)

The results suggest that "long-acting injections are well tolerated and lead to improved adherence in patients facing challenges with oral medications," the authors presented. (medscape.com)
The cost of healthcare has risen dramatically in recent years, and non-adherence to medications is a significant contributor to the rising costs. (revenuexl.com)

Race/ethnicity, baseline physical function, quality of life by SF-36, depressive symptoms, HIV characteristics, comorbidity burden, or use of antidepressants or antihypertensives were not significantly associated with adherence. (natap.org)
Determining factors that are mainly responsible for this high risk for OSA including factors such as nasal symptoms, nasal inflammation and nasal resistance. (cdc.gov)

This study was conducted to investigate the prevalence of methicillin resistance Staphylococcus aureus among patients in two health facilities in Akwa Ibom State, Nigeria. (who.int)
The factors suggested for the rising incidence include (i) limited qualified personnel to implement the management guidelines, (ii) lack of appropriate audiological equipment for screening the patients on injectable second-line anti-TB drugs, (iii) health care personnel's negative attitude towards patients with hearing loss, and (iv) lack of adherence to the DR-TB guidelines/improper implementation of the guideline (Carroll et al. (researchsquare.com)
The findings indicate that there are various strategies that may be effective in increasing adherence to exercise and physical activity in patients suffering from CMP. (racgp.org.au)
ART has been found to fail in nearly half of the patients for whom it is prescribed mainly due to non-adherence. (theseoultimes.com)

Accuracy of exercise performance (ie the extent to which participants perform the exercises correctly) and adherence may be improved by refresher or follow-up sessions and supplementing face-to-face instruction with other material such as an audiotape or videotape of the exercises (low-level evidence, two studies). (racgp.org.au)

A deep understanding of the Nap structure and adhesion mechanism will facilitate the development of anti-adherence therapies. (nature.com)
Some strains of M catarrhalis have pili or fimbriae, which may facilitate adherence to the respiratory epithelium. (medscape.com)

Resistance to certain hepatitis C drugs can disappear within months. (treatmentactiongroup.org)

This study will determine the effects of yoga on the psychological wellbeing of people with mild-to-moderate PD and will compare these effects with those of stretching and resistance training exercises. (biomedcentral.com)
Moderate-level* evidence from 17 trials suggests exercise type (eg aerobic versus resistance exercise, water-based versus land-based exercise, back-specific stabilisation versus general exercise, high- versus low-intensity exercise) does not affect adherence. (racgp.org.au)
Supervised exercise was found to be more effective than unsupervised/home exercise at increasing exercise adherence (moderate-level evidence, two studies). (racgp.org.au)

Most people who are not cured have resistance to one or more of the HCV drugs they've taken. (treatmentactiongroup.org)

Resistance to most chemicals and alkali, even in high concentrations. (porcelanosa.com)
Occurrence of high level methicillin resistance staphylococcus aureus. (who.int)
Additional strategies are needed to better engage and promote adherence in other PWH that are at high risk of nonadherence but likely to benefit from regular exercise. (natap.org)
It has a high wear resistance, it's easy to apply and to clean with UV resistance. (bisazza.com)
Incidence of type 2 diabetes and insulin resistance was high in the ageing HIV population. (lu.se)

A striking problem was that some hospitals still had outbreaks despite strict adherence to endoscopic reprocessing guidelines [ 9 ]. (hindawi.com)
There is compelling evidence for low adherence to hand hygiene guidelines in the operating room and thus an urgent need for effective improvement strategies," the study authors concluded. (beckershospitalreview.com)

He further explained to Citizen News Service (CNS): "Understanding these factors can increase providers attention to adherence. (theseoultimes.com)

It has been shown that muscle protein synthetic rate (MPS) is elevated in humans by 50% at 4 hrs following a bout of heavy resistance training, and by 109% at 24 hrs following training. (researchgate.net)

For 8 weeks, the yoga group will receive a weekly 90-min session of yoga, and the control group will receive a weekly 60-min session of stretching and resistance exercises. (biomedcentral.com)
This study will be the first randomized trial to compare the effect of yoga versus stretching and resistance training exercises in a PD population. (biomedcentral.com)

Reduced adherence, including less supervision, increases the risk of vivax recurrence. (biomedcentral.com)
It is concluded that following a bout of heavy resistance training, MPS increases rapidly, is more than double at 24 hrs, and thereafter declines rapidly so that at 36 hrs it has almost returned to baseline. (researchgate.net)

In a systematic review of 30 studies from low-income settings in 2011 [ 5 ], 80% and 88% of children failing first-line ART had 1 or more International AIDS Society (IAS)-USA major nucleoside reverse transcriptase inhibitor (NRTI) and non-nucleoside reverse transcriptase inhibitor (NNRTI) resistance-associated mutations, respectively. (prolekare.cz)

This study investigated the effect of reduced adherence on the risk of P. vivax recurrence. (biomedcentral.com)
The effect of adherence to primaquine on the incidence of P. vivax recurrence between days 7 and 90 was investigated by Cox regression analysis. (biomedcentral.com)

The second was to characterise the patterns of long-term virological control and resistance in children receiving first-line ART in sub-Saharan Africa without frequent, regular real-time VL monitoring (reflecting the reality in most ART programmes) in an observational analysis without regard to the trial randomisations. (prolekare.cz)

A total of 126 subjects will be recruited and randomly divided into yoga ( n = 63) or stretching and resistance exercise ( n = 63) groups. (biomedcentral.com)
Moreover, it is widely established that 2 important factors mediate muscle mass and function, which includes the synergistic effects of strategic amino acid provision and resistance exercise ( 11,13 ). (lww.com)
Despite the known benefits of exercise, however, long-term adherence remains low. (natap.org)
following heavy resistance exercise. (researchgate.net)
Fifteen of the 17 trials that evaluated different types of exercise were unable to detect between-group differences in adherence. (racgp.org.au)

J Strength Cond Res 31(4): 869-881, 2017-Resistance training (RT) with nutritional strategies incorporating whey protein intake postexercise can stimulate muscle protein synthesis and elicit hypertrophy. (lww.com)

Excellent adherence and mechanical resistance. (porcelanosa.com)
The copper foil backing of the tape offers excellent resistance against oxidation and discoloration. (3m.com)

Therefore, a short-term period of DT can potentially retain lower-body strength in young resistance-trained men irrespective of supplementing with 25 g of whey protein postexercise. (lww.com)

Some bacteria can transfer their resistance to antibiotics to other bacteria, which can cause more problems. (bd.com)

Anatomy16

Organisms30

Diseases14

Chemicals and Drugs70

Analytical, Diagnostic and Therapeutic Techniques and Equipment48

Psychiatry and Psychology6

Phenomena and Processes74

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture1

Information Science7

Health Care22

Geographicals1

Antimicrobial Resistance6

Regimens8

Antiretroviral therapy2

Medication18

Barriers2

Nasal resistance due to nasal inflammation2

Efficacy6

Viral3

Intervention5

20231

Regimen1

Outcomes5

Drug13

Confers resistance2

Multidrug Resistance1

Chronic4

Acrylic1

Patient1

Improve5

Treatment10

Antibiotic resistance5

Poor4

Doses2

Adhesive1

Barrier2

Therapy6

Medications2

Symptoms2

Patients4

Participants1

Facilitate2

Hepatitis1

Moderate3

Drugs1

High5

Guidelines2

Increase1

Humans1

Exercises2

Increases2

AIDS1

Vivax2

Patterns1

Exercise5

Strategies1

Excellent2

Lower1

Bacteria1