There was an error running the query [insert into queries_english (query,last) values ('adenosine 5' n ethylcarboxamide',curdate()) on duplicate key update repetitions=repetitions+1, last=curdate() - You have an error in your SQL syntax; check the manual that corresponds to your MySQL server version for the right syntax to use near 'n ethylcarboxamide',curdate()) on duplicate key update repetitions=repetitions+1' at line 1]Adenosine 5' n ethylcarboxamide. Medical search. FAQ
Loading...
There was an error running the query [select categoryid from categories where title like 'adenosine 5' n ethylcarboxamide' limit 1 - You have an error in your SQL syntax; check the manual that corresponds to your MySQL server version for the right syntax to use near 'n ethylcarboxamide' limit 1' at line 1]
  • vasodilation
  • Although adenosine agonists were shown to attenuate pain behaviors in a variety of animal models, adenosine agonists are also implicated in the regulation of many physiologic processes, especially cardiovascular and neurologic, which either reduce the activity of excitable tissues ( e.g. , by slowing heart rate) or increase the delivery of metabolic substrates ( e.g. , inducing vasodilation). (asahq.org)
  • CGS21680
  • ASP5854 ameliorated A(2A) agonist 2-[p-(2-carboxyethyl) phenethylamino]-5'-N-ethylcarboxamidoadenosine (CGS21680)- and haloperidol-induced catalepsy in mice, with the minimum effective doses of 0.32 and 0.1 mg/kg, respectively, and it also improved haloperidol-induced catalepsy in rats at doses higher than 0.1 mg/kg. (curehunter.com)
  • calcium
  • The goal was to determine whether adenosine, by itself, directly regulates calcium signaling in human bronchial smooth muscle cells (HBSMC). (plu.mx)
  • Active
  • Generation of biologically active adenosine by TAM-like macrophages was measured in luciferase-based reporter assays. (springer.com)
  • Expression of ectonucleotidases also translated into increased levels of biologically active adenosine. (springer.com)
  • levels
  • In ovarian cancer, high levels of adenosine are due to tumor-specific expression of the ectonucleotidases CD39/ENTPD1 and CD73/ecto-5′-nucleotidase [ 7 ] which synergistically catalyze the degradation of extracellular immune-stimulatory ATP to immune-inhibitory adenosine. (springer.com)
  • Fibroblasts are activated by factors such as transforming growth factor β and inhibited by agents that elevate 3′,5′-cyclic adenosine monophosphate (cAMP) levels. (chapman.edu)
  • cells
  • Little, however, is known about the effect of adenosine on myeloid cells. (springer.com)
  • Considering that tumor associated macrophages (TAM) and myeloid-derived suppressor cells (MDSC) constitute up to 20 % of OvCA tissue, we investigated the effect of adenosine on myeloid cells and explored a possible contribution of myeloid cells to adenosine generation in vitro and ex vivo. (springer.com)
  • Adenosine generated by OvCA cells likely contributes to the recruitment of TAMs which further amplify adenosine-dependent immunosuppression via additional ectonucleotidase activity. (springer.com)
  • expression
  • Ovarian cancer (OvCA) tissues show abundant expression of the ectonucleotidases CD39 and CD73 which generate immunomodulatory adenosine, thereby inhibiting cytotoxic lymphocytes. (springer.com)